IVApr 24
Generalizable CT-Free PET Attenuation and Scatter Correction for Pediatric PatientsJia-Mian Wu, Jun Liu, Siqi Li et al.
Computed tomography (CT)-based attenuation and scatter correction improves quantitative PET but adds radiation exposure that is particularly undesirable in pediatric imaging. Existing CT-free methods are commonly trained in homogeneous settings and often degrade under scanner or radiotracer shifts, which limits their clinical utility. We propose the Generalizable PET Correction Network (GPCN), a dual-domain network for domain-robust CT-free PET attenuation and scatter correction. GPCN combines a multi-band contextual refinement module, which models pediatric anatomical variability through wavelet-based multiscale decomposition and long-range spatial context modeling, with a frequency-aware spectral decoupling module, which performs coordinate-conditioned amplitude/phase refinement in the Fourier domain. By synergizing multi-band spatial contextual modeling with asymmetric frequency-spectrum decoupling, the network explicitly separates invariant topological structures from domain-specific noise, thereby achieving precise quantitative recovery of both anatomical organs and focal lesions. This design aims to separate anatomy-dominant structures from domain-sensitive spectral residuals and to improve robustness across heterogeneous imaging conditions. We train and evaluate the method on 1085 pediatric whole-body PET scans acquired with two scanners and five radiotracers. In both joint training and zero-shot cross-domain evaluation, GPCN outperforms representative baselines and maintains stable quantitative accuracy on unseen scanner-tracer combinations. The method is further supported by ablation, region-wise quantitative analysis, and downstream segmentation experiments. In our cohort, the CT component of the conventional protocol corresponded to an average effective dose of 10.8 mSv, indicating the potential clinical value of reliable CT-free correction for pediatric PET.
IRJun 10, 2024
Survey for Landing Generative AI in Social and E-commerce Recsys -- the Industry PerspectivesDa Xu, Danqing Zhang, Guangyu Yang et al.
Recently, generative AI (GAI), with their emerging capabilities, have presented unique opportunities for augmenting and revolutionizing industrial recommender systems (Recsys). Despite growing research efforts at the intersection of these fields, the integration of GAI into industrial Recsys remains in its infancy, largely due to the intricate nature of modern industrial Recsys infrastructure, operations, and product sophistication. Drawing upon our experiences in successfully integrating GAI into several major social and e-commerce platforms, this survey aims to comprehensively examine the underlying system and AI foundations, solution frameworks, connections to key research advancements, as well as summarize the practical insights and challenges encountered in the endeavor to integrate GAI into industrial Recsys. As pioneering work in this domain, we hope outline the representative developments of relevant fields, shed lights on practical GAI adoptions in the industry, and motivate future research.
DCJan 8, 2024
Why does Prediction Accuracy Decrease over Time? Uncertain Positive Learning for Cloud Failure PredictionHaozhe Li, Minghua Ma, Yudong Liu et al.
With the rapid growth of cloud computing, a variety of software services have been deployed in the cloud. To ensure the reliability of cloud services, prior studies focus on failure instance (disk, node, and switch, etc.) prediction. Once the output of prediction is positive, mitigation actions are taken to rapidly resolve the underlying failure. According to our real-world practice in Microsoft Azure, we find that the prediction accuracy may decrease by about 9% after retraining the models. Considering that the mitigation actions may result in uncertain positive instances since they cannot be verified after mitigation, which may introduce more noise while updating the prediction model. To the best of our knowledge, we are the first to identify this Uncertain Positive Learning (UPLearning) issue in the real-world cloud failure prediction scenario. To tackle this problem, we design an Uncertain Positive Learning Risk Estimator (Uptake) approach. Using two real-world datasets of disk failure prediction and conducting node prediction experiments in Microsoft Azure, which is a top-tier cloud provider that serves millions of users, we demonstrate Uptake can significantly improve the failure prediction accuracy by 5% on average.