Luoxi Tang

Adarsh Pawar, Yuqiao Meng, Luoxi Tang et al.

The Fast Healthcare Interoperability Resources (FHIR) standard has emerged as a widely adopted specification for exchanging structured clinical data across healthcare systems. However, raw FHIR resources are often complex, verbose, and difficult for clinicians and analysts to interpret without specialized tooling. This paper presents a lightweight, browser-based system that improves the accessibility of FHIR data by automatically transforming raw JSON resources into human-readable PDF and Excel reports, along with interactive data visualizations. The system supports both remote retrieval of FHIR resources from server endpoints and the upload of local FHIR JSON files, enabling both online and offline analysis. Using a modular React architecture with jsPDF, xlsx, and Recharts, the tool parses, normalizes, visualizes, and exports FHIR data in an intuitive format. Evaluation results demonstrate that the system enhances interpretability and usability while preserving the semantic integrity of FHIR structures. Limitations and future extensions, including expanded FHIR profile support and clinical validation, are discussed.

Rafael Brens, Yuqiao Meng, Luoxi Tang et al.

Digital twins -- virtual replicas of physical entities -- are gaining traction in healthcare for personalized monitoring, predictive modeling, and clinical decision support. However, generating interoperable patient digital twins from unstructured electronic health records (EHRs) remains challenging due to variability in clinical documentation and lack of standardized mappings. This paper presents a semantic NLP-driven pipeline that transforms free-text EHR notes into FHIR-compliant digital twin representations. The pipeline leverages named entity recognition (NER) to extract clinical concepts, concept normalization to map entities to SNOMED-CT or ICD-10, and relation extraction to capture structured associations between conditions, medications, and observations. Evaluation on MIMIC-IV Clinical Database Demo with validation against MIMIC-IV-on-FHIR reference mappings demonstrates high F1-scores for entity and relation extraction, with improved schema completeness and interoperability compared to baseline methods.