Li Hao

CV
h-index39
7papers
43citations
Novelty50%
AI Score42

7 Papers

CHEM-PHFeb 6
LatentChem: From Textual CoT to Latent Thinking in Chemical Reasoning

Xinwu Ye, Yicheng Mao, Jia Zhang et al.

Chemical large language models (LLMs) predominantly rely on explicit Chain-of-Thought (CoT) in natural language to perform complex reasoning. However, chemical reasoning is inherently continuous and structural, and forcing it into discrete linguistic tokens introduces a fundamental representation mismatch that constrains both efficiency and performance. We introduce LatentChem, a latent reasoning interface that decouples chemical computation from textual generation, enabling models to perform multi-step reasoning directly in continuous latent space while emitting language only for final outputs. Remarkably, we observe a consistent emergent behavior: when optimized solely for task success, models spontaneously internalize reasoning, progressively abandoning verbose textual derivations in favor of implicit latent computation. This shift is not merely stylistic but computationally advantageous. Across diverse chemical reasoning benchmarks, LatentChem achieves a 59.88\% non-tie win rate over strong CoT-based baselines on ChemCoTBench, while delivering a 10.84$\times$ average inference speedup. Our results provide empirical evidence that chemical reasoning is more naturally and effectively realized as continuous latent dynamics rather than discretized linguistic trajectories.

LGFeb 27, 2024Code
TaxDiff: Taxonomic-Guided Diffusion Model for Protein Sequence Generation

Lin Zongying, Li Hao, Lv Liuzhenghao et al.

Designing protein sequences with specific biological functions and structural stability is crucial in biology and chemistry. Generative models already demonstrated their capabilities for reliable protein design. However, previous models are limited to the unconditional generation of protein sequences and lack the controllable generation ability that is vital to biological tasks. In this work, we propose TaxDiff, a taxonomic-guided diffusion model for controllable protein sequence generation that combines biological species information with the generative capabilities of diffusion models to generate structurally stable proteins within the sequence space. Specifically, taxonomic control information is inserted into each layer of the transformer block to achieve fine-grained control. The combination of global and local attention ensures the sequence consistency and structural foldability of taxonomic-specific proteins. Extensive experiments demonstrate that TaxDiff can consistently achieve better performance on multiple protein sequence generation benchmarks in both taxonomic-guided controllable generation and unconditional generation. Remarkably, the sequences generated by TaxDiff even surpass those produced by direct-structure-generation models in terms of confidence based on predicted structures and require only a quarter of the time of models based on the diffusion model. The code for generating proteins and training new versions of TaxDiff is available at:https://github.com/Linzy19/TaxDiff.

CVOct 8, 2021Code
2nd Place Solution to Google Landmark Retrieval 2021

Zhang Yuqi, Xu Xianzhe, Chen Weihua et al.

This paper presents the 2nd place solution to the Google Landmark Retrieval 2021 Competition on Kaggle. The solution is based on a baseline with training tricks from person re-identification, a continent-aware sampling strategy is presented to select training images according to their country tags and a Landmark-Country aware reranking is proposed for the retrieval task. With these contributions, we achieve 0.52995 mAP@100 on private leaderboard. Code available at https://github.com/WesleyZhang1991/Google_Landmark_Retrieval_2021_2nd_Place_Solution

CVNov 18, 2024
Stacking Brick by Brick: Aligned Feature Isolation for Incremental Face Forgery Detection

Jikang Cheng, Zhiyuan Yan, Ying Zhang et al.

The rapid advancement of face forgery techniques has introduced a growing variety of forgeries. Incremental Face Forgery Detection (IFFD), involving gradually adding new forgery data to fine-tune the previously trained model, has been introduced as a promising strategy to deal with evolving forgery methods. However, a naively trained IFFD model is prone to catastrophic forgetting when new forgeries are integrated, as treating all forgeries as a single ''Fake" class in the Real/Fake classification can cause different forgery types overriding one another, thereby resulting in the forgetting of unique characteristics from earlier tasks and limiting the model's effectiveness in learning forgery specificity and generality. In this paper, we propose to stack the latent feature distributions of previous and new tasks brick by brick, $\textit{i.e.}$, achieving $\textbf{aligned feature isolation}$. In this manner, we aim to preserve learned forgery information and accumulate new knowledge by minimizing distribution overriding, thereby mitigating catastrophic forgetting. To achieve this, we first introduce Sparse Uniform Replay (SUR) to obtain the representative subsets that could be treated as the uniformly sparse versions of the previous global distributions. We then propose a Latent-space Incremental Detector (LID) that leverages SUR data to isolate and align distributions. For evaluation, we construct a more advanced and comprehensive benchmark tailored for IFFD. The leading experimental results validate the superiority of our method.

CVMay 26, 2025
Guard Me If You Know Me: Protecting Specific Face-Identity from Deepfakes

Kaiqing Lin, Zhiyuan Yan, Ke-Yue Zhang et al. · tencent-ai

Securing personal identity against deepfake attacks is increasingly critical in the digital age, especially for celebrities and political figures whose faces are easily accessible and frequently targeted. Most existing deepfake detection methods focus on general-purpose scenarios and often ignore the valuable prior knowledge of known facial identities, e.g., "VIP individuals" whose authentic facial data are already available. In this paper, we propose \textbf{VIPGuard}, a unified multimodal framework designed to capture fine-grained and comprehensive facial representations of a given identity, compare them against potentially fake or similar-looking faces, and reason over these comparisons to make accurate and explainable predictions. Specifically, our framework consists of three main stages. First, fine-tune a multimodal large language model (MLLM) to learn detailed and structural facial attributes. Second, we perform identity-level discriminative learning to enable the model to distinguish subtle differences between highly similar faces, including real and fake variations. Finally, we introduce user-specific customization, where we model the unique characteristics of the target face identity and perform semantic reasoning via MLLM to enable personalized and explainable deepfake detection. Our framework shows clear advantages over previous detection works, where traditional detectors mainly rely on low-level visual cues and provide no human-understandable explanations, while other MLLM-based models often lack a detailed understanding of specific face identities. To facilitate the evaluation of our method, we built a comprehensive identity-aware benchmark called \textbf{VIPBench} for personalized deepfake detection, involving the latest 7 face-swapping and 7 entire face synthesis techniques for generation.

LGOct 29, 2024
Enhance Hyperbolic Representation Learning via Second-order Pooling

Kun Song, Ruben Solozabal, Li hao et al.

Hyperbolic representation learning is well known for its ability to capture hierarchical information. However, the distance between samples from different levels of hierarchical classes can be required large. We reveal that the hyperbolic discriminant objective forces the backbone to capture this hierarchical information, which may inevitably increase the Lipschitz constant of the backbone. This can hinder the full utilization of the backbone's generalization ability. To address this issue, we introduce second-order pooling into hyperbolic representation learning, as it naturally increases the distance between samples without compromising the generalization ability of the input features. In this way, the Lipschitz constant of the backbone does not necessarily need to be large. However, current off-the-shelf low-dimensional bilinear pooling methods cannot be directly employed in hyperbolic representation learning because they inevitably reduce the distance expansion capability. To solve this problem, we propose a kernel approximation regularization, which enables the low-dimensional bilinear features to approximate the kernel function well in low-dimensional space. Finally, we conduct extensive experiments on graph-structured datasets to demonstrate the effectiveness of the proposed method.

HCApr 7, 2016
MPP3D: Multi-Precision Pointing using the 3rd Dimension

Yaohua Xie, Danli Wang, Li Hao

Distant pointing is still not efficient, accurate or flexible enough for many applications, although many researchers have focused on it. To improve upon distant pointing, we propose MPP3D, which is especially suitable for high-resolution displays. MPP3D uses two dimensions of hand positioning to move a pointer, and it also uses the third dimension to adjust the precision of the movement. Based on the idea of MPP3D, we propose four techniques which combine two ways of mapping and two techniques for precision adjustment. We further provide three types of mapping scheme and visual feedback for each technique. The potential of the proposed techniques was investigated through experimentation. The results show that these techniques were competent for usual computer operations with a cursor, and the adjustment for pointing precision was beneficial for both pointing efficiency and accuracy.