Christopher Mansell

Luca Lusnig, Asel Sagingalieva, Mikhail Surmach et al.

In the realm of liver transplantation, accurately determining hepatic steatosis levels is crucial. Recognizing the essential need for improved diagnostic precision, particularly for optimizing diagnosis time by swiftly handling easy-to-solve cases and allowing the expert time to focus on more complex cases, this study aims to develop cutting-edge algorithms that enhance the classification of liver biopsy images. Additionally, the challenge of maintaining data privacy arises when creating automated algorithmic solutions, as sharing patient data between hospitals is restricted, further complicating the development and validation process. This research tackles diagnostic accuracy by leveraging novel techniques from the rapidly evolving field of quantum machine learning, known for their superior generalization abilities. Concurrently, it addresses privacy concerns through the implementation of privacy-conscious collaborative machine learning with federated learning. We introduce a hybrid quantum neural network model that leverages real-world clinical data to assess non-alcoholic liver steatosis accurately. This model achieves an image classification accuracy of 97%, surpassing traditional methods by 1.8%. Moreover, by employing a federated learning approach that allows data from different clients to be shared while ensuring privacy, we maintain an accuracy rate exceeding 90%. This initiative marks a significant step towards a scalable, collaborative, efficient, and dependable computational framework that aids clinical pathologists in their daily diagnostic tasks.

Matvei Anoshin, Asel Sagingalieva, Christopher Mansell et al.

The drug design process currently requires considerable time and resources to develop each new compound that enters the market. This work develops an application of hybrid quantum generative models based on the integration of parametrized quantum circuits into known molecular generative adversarial networks, and proposes quantum cycle architectures that improve model performance and stability during training. Through extensive experimentation on benchmark drug design datasets, QM9 and PC9, the introduced models are shown to outperform the previously achieved scores. Most prominently, the new scores indicate an increase of up to 30% in the quantitative estimation of druglikeness. The new hybrid quantum machine learning algorithms, as well as the achieved scores of pharmacokinetic properties, contribute to the development of fast and accurate drug discovery processes.

Asel Sagingalieva, Stefan Komornyik, Arsenii Senokosov et al.

Accurate forecasting of photovoltaic power is essential for reliable grid integration, yet remains difficult due to highly variable irradiance, complex meteorological drivers, site geography, and device-specific behavior. Although contemporary machine learning has achieved successes, it is not clear that these approaches are optimal: new model classes may further enhance performance and data efficiency. We investigate hybrid quantum neural networks for time-series forecasting of photovoltaic power and introduce two architectures. The first, a Hybrid Quantum Long Short-Term Memory model, reduces mean absolute error and mean squared error by more than 40% relative to the strongest baselines evaluated. The second, a Hybrid Quantum Sequence-to-Sequence model, once trained, it predicts power for arbitrary forecast horizons without requiring prior meteorological inputs and achieves a 16% lower mean absolute error than the best baseline on this task. Both hybrid models maintain superior accuracy when training data are limited, indicating improved data efficiency. These results show that hybrid quantum models address key challenges in photovoltaic power forecasting and offer a practical route to more reliable, data-efficient energy predictions.