Xinyuan Li

Xinyuan Li, Yu Ji, Yanchen Liu et al.

Reconstructing and tracking deformable surface with little or no texture has posed long-standing challenges. Fundamentally, the challenges stem from textureless surfaces lacking features for establishing cross-image correspondences. In this work, we present a novel type of markers to proactively enrich the object's surface features, and thereby ease the 3D surface reconstruction and correspondence tracking. Our markers are made of fluorescent dyes, visible only under the ultraviolet (UV) light and invisible under regular lighting condition. Leveraging the markers, we design a multi-camera system that captures surface deformation under the UV light and the visible light in a time multiplexing fashion. Under the UV light, markers on the object emerge to enrich its surface texture, allowing high-quality 3D shape reconstruction and tracking. Under the visible light, markers become invisible, allowing us to capture the object's original untouched appearance. We perform experiments on various challenging scenes, including hand gestures, facial expressions, waving cloth, and hand-object interaction. In all these cases, we demonstrate that our system is able to produce robust, high-quality 3D reconstruction and tracking.

Yu-An Huang, Yue-Chao Li, Hai-Ru You et al.

The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however, lack spatial context and rely on incomplete datasets of ligand-receptor interactions (LRIs), limiting accurate cell type annotation and cell-cell communication (CCC) inference. This study addresses these challenges using a novel graph neural network (GNN) model that enhances cell type prediction and cell interaction analysis. Our study utilized a dataset consisting of 49,020 cells from 19 patients across three cancer types: Leukemia, Breast Invasive Carcinoma, and Colorectal Cancer. The proposed scGSL model demonstrated robust performance, achieving an average accuracy of 84.83%, precision of 86.23%, recall of 81.51%, and an F1 score of 80.92% across all datasets. These metrics represent a significant enhancement over existing methods, which typically exhibit lower performance metrics. Additionally, by reviewing existing literature on gene interactions within the TME, the scGSL model proves to robustly identify biologically meaningful gene interactions in an unsupervised manner, validated by significant expression differences in key gene pairs across various cancers. The source code and data used in this paper can be found in https://github.com/LiYuechao1998/scGSL.