Aymen Alsaadi

h-index38
2papers

2 Papers

75.7DCMay 4
AAFLOW: Scalable Patterns for Agentic AI Workflows

Arup Kumar Sarker, Mills Staylor, Aymen Alsaadi et al.

Agentic workflows in large language model systems integrate retrieval, reasoning, and memory, but existing frameworks suffer from scalability and reproducibility limitations due to fragmented data orchestration, serialization overhead, and non-deterministic execution. Although these frameworks increase flexibility, they don't have a formal execution model that adheres to the principles of high-performance computing. We introduce AAFLOW, a unified distributed runtime that creates communication-efficient execution plans by modeling agentic workflows as an operator abstraction. Using Apache Arrow and Cylon, AAFLOW creates a zero-copy data plane that allows direct interoperability between preprocessing, embedding, and vector retrieval without the need for serialization overhead. To lower coordination costs, it uses resource-deterministic scheduling and asynchronous batching. While retaining comparable LLM generation throughput, experimental results demonstrate up to 4.64 times pipeline speedup and 2.8 times gains in embedding and upsert phases. Rather than LLM inference acceleration, these advantages result from enhanced data flow, batching, and communication efficiency.

DCOct 7, 2025
Adaptive Protein Design Protocols and Middleware

Aymen Alsaadi, Jonathan Ash, Mikhail Titov et al.

Computational protein design is experiencing a transformation driven by AI/ML. However, the range of potential protein sequences and structures is astronomically vast, even for moderately sized proteins. Hence, achieving convergence between generated and predicted structures demands substantial computational resources for sampling. The Integrated Machine-learning for Protein Structures at Scale (IMPRESS) offers methods and advanced computing systems for coupling AI to high-performance computing tasks, enabling the ability to evaluate the effectiveness of protein designs as they are developed, as well as the models and simulations used to generate data and train models. This paper introduces IMPRESS and demonstrates the development and implementation of an adaptive protein design protocol and its supporting computing infrastructure. This leads to increased consistency in the quality of protein design and enhanced throughput of protein design due to dynamic resource allocation and asynchronous workload execution.