Guoan Wang

Guoan Wang, Shihao Yang, Jun-en Ding et al.

Electroencephalography (EEG) provides a non-invasive window into neural dynamics at high temporal resolution and plays a pivotal role in clinical neuroscience research. Despite this potential, prevailing computational approaches to EEG analysis remain largely confined to task-specific classification objectives or coarse-grained pattern recognition, offering limited support for clinically meaningful interpretation. To address these limitations, we introduce NeuroNarrator, the first generalist EEG-to-text foundation model designed to translate electrophysiological segments into precise clinical narratives. A cornerstone of this framework is the curation of NeuroCorpus-160K, the first harmonized large-scale resource pairing over 160,000 EEG segments with structured, clinically grounded natural-language descriptions. Our architecture first aligns temporal EEG waveforms with spatial topographic maps via a rigorous contrastive objective, establishing spectro-spatially grounded representations. Building on this grounding, we condition a Large Language Model through a state-space-inspired formulation that integrates historical temporal and spectral context to support coherent clinical narrative generation. This approach establishes a principled bridge between continuous signal dynamics and discrete clinical language, enabling interpretable narrative generation that facilitates expert interpretation and supports clinical reporting workflows. Extensive evaluations across diverse benchmarks and zero-shot transfer tasks highlight NeuroNarrator's capacity to integrate temporal, spectral, and spatial dynamics, positioning it as a foundational framework for time-frequency-aware, open-ended clinical interpretation of electrophysiological data.

Guoan Wang, Shihao Yang, Jun-En Ding et al.

Although foundation models have demonstrated remarkable success in general domains, the application of these models to electroencephalography (EEG) analysis is constrained by substantial data requirements and high parameterization. These factors incur prohibitive computational costs, thereby impeding deployment in resource-constrained clinical environments. Conversely, general-purpose automated machine learning frameworks are often ill-suited for this domain, as exploration within an unbounded programmatic space fails to incorporate essential neurophysiological priors and frequently yields solutions that lack scientific plausibility. To address these limitations, we propose NeuroWeaver, a unified autonomous evolutionary agent designed to generalize across diverse EEG datasets and tasks by reformulating pipeline engineering as a discrete constrained optimization problem. Specifically, we employ a Domain-Informed Subspace Initialization to confine the search to neuroscientifically plausible manifolds, coupled with a Multi-Objective Evolutionary Optimization that dynamically balances performance, novelty, and efficiency via self-reflective refinement. Empirical evaluations across five heterogeneous benchmarks demonstrate that NeuroWeaver synthesizes lightweight solutions that consistently outperform state-of-the-art task-specific methods and achieve performance comparable to large-scale foundation models, despite utilizing significantly fewer parameters.