Feng Gao

Feng Gao, Zheng Gong, Wenli Liu et al.

While Mamba models offer efficient sequence modeling, vanilla versions struggle with temporal correlations and boundary details in Arctic sea ice concentration (SIC) prediction. To address these limitations, we propose Frequency-enhanced Hilbert scanning Mamba Framework (FH-Mamba) for short-term Arctic SIC prediction. Specifically, we introduce a 3D Hilbert scan mechanism that traverses the 3D spatiotemporal grid along a locality-preserving path, ensuring that adjacent indices in the flattened sequence correspond to neighboring voxels in both spatial and temporal dimensions. Additionally, we incorporate wavelet transform to amplify high-frequency details and we also design a Hybrid Shuffle Attention module to adaptively aggregate sequence and frequency features. Experiments conducted on the OSI-450a1 and AMSR2 datasets demonstrate that our FH-Mamba achieves superior prediction performance compared with state-of-the-art baselines. The results confirm the effectiveness of Hilbert scanning and frequency-aware attention in improving both temporal consistency and edge reconstruction for Arctic SIC forecasting. Our codes are publicly available at https://github.com/oucailab/FH-Mamba.

Yu Cai, Cheng Jin, Jiabo Ma et al.

Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide images, limits clinical accessibility and scalability. Here, we present LitePath, a deployment-friendly foundational framework designed to mitigate model over-parameterization and patch level redundancy. LitePath integrates LiteFM, a compact model distilled from three large PFMs (Virchow2, H-Optimus-1 and UNI2) using 190 million patches, and the Adaptive Patch Selector (APS), a lightweight component for task-specific patch selection. The framework reduces model parameters by 28x and lowers FLOPs by 403.5x relative to Virchow2, enabling deployment on low-power edge hardware such as the NVIDIA Jetson Orin Nano Super. On this device, LitePath processes 208 slides per hour, 104.5x faster than Virchow2, and consumes 0.36 kWh per 3,000 slides, 171x lower than Virchow2 on an RTX3090 GPU. We validated accuracy using 37 cohorts across four organs and 26 tasks (26 internal, 9 external, and 2 prospective), comprising 15,672 slides from 9,808 patients disjoint from the pretraining data. LitePath ranks second among 19 evaluated models and outperforms larger models including H-Optimus-1, mSTAR, UNI2 and GPFM, while retaining 99.71% of the AUC of Virchow2 on average. To quantify the balance between accuracy and efficiency, we propose the Deployability Score (D-Score), defined as the weighted geometric mean of normalized AUC and normalized FLOP, where LitePath achieves the highest value, surpassing Virchow2 by 10.64%. These results demonstrate that LitePath enables rapid, cost-effective and energy-efficient pathology image analysis on accessible hardware while maintaining accuracy comparable to state-of-the-art PFMs and reducing the carbon footprint of AI deployment.