Xiaotian Han

Jingfeng Yang, Hongye Jin, Ruixiang Tang et al. · amazon-science

This paper presents a comprehensive and practical guide for practitioners and end-users working with Large Language Models (LLMs) in their downstream natural language processing (NLP) tasks. We provide discussions and insights into the usage of LLMs from the perspectives of models, data, and downstream tasks. Firstly, we offer an introduction and brief summary of current GPT- and BERT-style LLMs. Then, we discuss the influence of pre-training data, training data, and test data. Most importantly, we provide a detailed discussion about the use and non-use cases of large language models for various natural language processing tasks, such as knowledge-intensive tasks, traditional natural language understanding tasks, natural language generation tasks, emergent abilities, and considerations for specific tasks.We present various use cases and non-use cases to illustrate the practical applications and limitations of LLMs in real-world scenarios. We also try to understand the importance of data and the specific challenges associated with each NLP task. Furthermore, we explore the impact of spurious biases on LLMs and delve into other essential considerations, such as efficiency, cost, and latency, to ensure a comprehensive understanding of deploying LLMs in practice. This comprehensive guide aims to provide researchers and practitioners with valuable insights and best practices for working with LLMs, thereby enabling the successful implementation of these models in a wide range of NLP tasks. A curated list of practical guide resources of LLMs, regularly updated, can be found at \url{https://github.com/Mooler0410/LLMsPracticalGuide}.

Ruixiang Tang, Xiaotian Han, Xiaoqian Jiang et al.

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay composition, and code generation. However, their effectiveness in the healthcare sector remains uncertain. In this study, we seek to investigate the potential of ChatGPT to aid in clinical text mining by examining its ability to extract structured information from unstructured healthcare texts, with a focus on biological named entity recognition and relation extraction. However, our preliminary results indicate that employing ChatGPT directly for these tasks resulted in poor performance and raised privacy concerns associated with uploading patients' information to the ChatGPT API. To overcome these limitations, we propose a new training paradigm that involves generating a vast quantity of high-quality synthetic data with labels utilizing ChatGPT and fine-tuning a local model for the downstream task. Our method has resulted in significant improvements in the performance of downstream tasks, improving the F1-score from 23.37% to 63.99% for the named entity recognition task and from 75.86% to 83.59% for the relation extraction task. Furthermore, generating data using ChatGPT can significantly reduce the time and effort required for data collection and labeling, as well as mitigate data privacy concerns. In summary, the proposed framework presents a promising solution to enhance the applicability of LLM models to clinical text mining.

Yicheng Wang, Xiaotian Han, Leisheng Yu et al.

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models currently have fairness issues regarding different ages of onset. These deep models perform well for the elderly group (age $>$ 55) but are less accurate for the young group (age $\leq$ 55). Through our investigation, the discrepancy between the elderly and the young arises due to 1) an imbalanced dataset and 2) the milder symptoms often seen in early-onset patients. However, traditional debiasing methods are impractical as they typically impair the prediction accuracy for the majority group while minimizing the discrepancy. To address this issue, we present a new debiasing method using GradCAM-based feature masking combined with ensemble models, ensuring that neither fairness nor accuracy is compromised. Specifically, the GradCAM-based feature masking selectively obscures age-related features in the input voice data while preserving essential information for PD detection. The ensemble models further improve the prediction accuracy for the minority (young group). Our approach effectively improves detection accuracy for early-onset patients without sacrificing performance for the elderly group. Additionally, we propose a two-step detection strategy for the young group, offering a practical risk assessment for potential early-onset PD patients.

Mohsen Hariri, Alan Luo, Weicong Chen et al.

Large Language Models (LLMs) suffer inference-time memory bottlenecks dominated by the attention Key-Value (KV) cache, which scales with model size and context length. While KV-cache quantization alleviates this cost, bit allocation between keys and values is often tuned heuristically, lacking theoretical grounding and generalizability. This paper proposes two theorems that anchor mixed-precision KV quantization in the intrinsic geometry of Transformer models. First, key projections systematically have larger spectral and Frobenius norms than value matrices, implying higher information density along the key path. Second, for any given memory budget, prioritizing precision for keys over values strictly reduces quantization error and better preserves accuracy. Empirical evaluations across various prominent LLMs and benchmarks show that key-favored allocations (e.g., 4-bit keys, 2-bit values) retain up to 98.3\% accuracy compared to uniform allocations (e.g., 4-bit for both), while conserving memory. These results transform bit allocation from ad hoc tuning into a theoretically grounded, geometry-driven design principle for efficient LLM inference. Source code is available at https://github.com/mohsenhariri/spectral-kv.

Wang Yang, Hongye Jin, Shaochen Zhong et al.

Long-context capability is considered one of the most important abilities of LLMs, as a truly long context-capable LLM enables users to effortlessly process many originally exhausting tasks -- e.g., digesting a long-form document to find answers vs. directly asking an LLM about it. However, existing real-task-based long-context evaluation benchmarks have two major shortcomings. First, benchmarks like LongBench often do not provide proper metrics to separate long-context performance from the model's baseline ability, making cross-model comparison unclear. Second, such benchmarks are usually constructed with fixed input lengths, which limits their applicability across different models and fails to reveal when a model begins to break down. To address these issues, we introduce a length-controllable long-context benchmark and a novel metric that disentangles baseline knowledge from true long-context capabilities. Experiments demonstrate the superiority of our approach in effectively evaluating LLMs.