Yuci Liang

Jing Hao, Siyuan Dai, Yongxin Zhang et al.

Dental image analysis plays a pivotal role in supporting accurate diagnosis and treatment planning in oral healthcare. Although recent advances have produced dental AI models for specific tasks and individual imaging modalities, their isolated designs limit practical use in real-world clinical workflows. In this paper, we present OralAgent, the first dental-specialized AI agent that unifies multimodal reasoning, tool-based decision-making, and knowledge-grounded retrieval within an end-to-end automated framework. It integrates 22 visual analysis tools and 368 widely-used classical dental textbooks, enabling autonomous reasoning, planning, tool use, knowledge retrieval, and multi-step workflow execution. Furthermore, we introduce OralCorpus, a large-scale, high-quality bilingual textual resource containing 134.8M tokens curated for dental retrieval-augmented generation (RAG). To evaluate models' multidisciplinary dental knowledge, we construct OralQA-ZH, a Chinese multiple-choice question benchmark consisting of 798 items across eleven oral subspecialties. Extensive experiments demonstrate that OralAgent achieves state-of-the-art performance on the MMOral-Uni, MMOral-OPG, and OralQA-ZH benchmarks, highlighting its effectiveness, interpretability, and adaptability in real-world clinical settings. The code and models are publicly available at https://github.com/isjinghao/OralAgent.

Jinyue Li, Yuci Liang, Qiankun Li et al.

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking morphological evidence with formal diagnostic and grading criteria. Although multimodal large language models (MLLMs) demonstrate strong vision language reasoning capabilities, they lack explicit mechanisms for structured knowledge integration and interpretable memory control. As a result, existing models struggle to consistently incorporate pathology-specific diagnostic standards during reasoning. Inspired by the hierarchical memory process of human pathologists, we propose PathMem, a memory-centric multimodal framework for pathology MLLMs. PathMem organizes structured pathology knowledge as a long-term memory (LTM) and introduces a Memory Transformer that models the dynamic transition from LTM to working memory (WM) through multimodal memory activation and context-aware knowledge grounding, enabling context-aware memory refinement for downstream reasoning. PathMem achieves SOTA performance across benchmarks, improving WSI-Bench report generation (12.8% WSI-Precision, 10.1% WSI-Relevance) and open-ended diagnosis by 9.7% and 8.9% over prior WSI-based models.

Yuxuan Fan, Jing Hao, Hong Chen et al.

Panoramic dental radiographs require fine-grained spatial reasoning, bilateral symmetry understanding, and multi-step diagnostic verification, yet existing vision-language models operate under a static single-pass paradigm that limits their clinical reliability. In this paper, we introduce OralGPT-Plus, an agentic vision-language model designed to perform iterative and symmetry-aware diagnostic reasoning for panoramic dental radiograph analysis. To support this paradigm, we construct DentalProbe, a five-thousand-image dataset with expert-curated diagnostic trajectories that provide structured supervision for localized inspection and contralateral comparison. We further develop a Reinspection-driven reinforcement learning framework that encourages clinically meaningful re-examination and stabilizes long-horizon reasoning with rubric-based reward and conditioned diagnostic-driven reward. In parallel, we present MMOral-X, the first benchmark for holistic panoramic diagnosis, containing 300 open-ended questions and region-level annotations across multiple difficulty levels. OralGPT-Plus demonstrates consistent and reliable improvements over strong baselines on MMOral-X and established panoramic benchmarks, indicating the effectiveness of interactive and symmetry-informed reasoning. Our work highlights the value of agentic modeling for dental imaging and provides a foundation for future research in clinically aligned panoramic radiograph analysis.