Jun Xiao

Sijing Li, Zhongwei Qiu, Jiang Liu et al.

Accurate tumor analysis is central to clinical radiology and precision oncology, where early detection, reliable lesion characterization, and pathology-level risk assessment guide diagnosis and treatment planning. Chain-of-Thought (CoT) reasoning is particularly important in this setting because it enables step-by-step interpretation from imaging findings to clinical impressions and pathology conclusions, improving traceability and reducing diagnostic errors. Here, we target the clinical tumor analysis task and build a large-scale benchmark that operationalizes a multimodal reasoning pipeline, spanning findings, impressions, and pathology predictions. We curate TumorCoT, a large-scale dataset of 1.5M CoT-labeled VQA instructions paired with 3D CT scans, with step-aligned rationales and cross-modal alignments along the trajectory from findings to impression to pathology, enabling evaluation of both answer accuracy and reasoning consistency. We further propose TumorChain, a multimodal interleaved reasoning framework that tightly couples 3D imaging encoders, clinical text understanding, and organ-level vision-language alignment. Through cross-modal alignment and iterative interleaved causal reasoning, TumorChain grounds visual evidence, aggregates conclusions, and issues pathology predictions after multiple rounds of self-refinement, improving traceability and reducing hallucination risk. Experiments show consistent improvements over strong baselines in lesion detection, impression generation, and pathology classification, and demonstrate strong generalization on the DeepTumorVQA benchmark. These results highlight the potential of multimodal reasoning for reliable and interpretable tumor analysis in clinical practice. Detailed information about our project can be found on our project homepage at https://github.com/ZJU4HealthCare/TumorChain.

Zhen Wang, Youcan Xu, Jun Xiao et al.

Video motion transfer aims to generate a target video that inherits motion patterns from a source video while rendering new scenes. Existing training-free approaches focus on constructing motion guidance based on the intermediate outputs of pre-trained T2V models, which results in heavy computational overhead and limited flexibility. In this paper, we present FlowMotion, a novel training-free framework that enables efficient and flexible motion transfer by directly leveraging the predicted outputs of flow-based T2V models. Our key insight is that early latent predictions inherently encode rich temporal information. Motivated by this, we propose flow guidance, which extracts motion representations based on latent predictions to align motion patterns between source and generated videos. We further introduce a velocity regularization strategy to stabilize optimization and ensure smooth motion evolution. By operating purely on model predictions, FlowMotion achieves superior time and resource efficiency as well as competitive performance compared with state-of-the-art methods.