Yuli Wu

Long Chen, Weiwen Zhang, Yuli Wu et al.

To date, most instance segmentation approaches are based on supervised learning that requires a considerable amount of annotated object contours as training ground truth. Here, we propose a framework that searches for the target object based on a shape prior. The shape prior model is learned with a variational autoencoder that requires only a very limited amount of training data: In our experiments, a few dozens of object shape patches from the target dataset, as well as purely synthetic shapes, were sufficient to achieve results en par with supervised methods with full access to training data on two out of three cell segmentation datasets. Our method with a synthetic shape prior was superior to pre-trained supervised models with access to limited domain-specific training data on all three datasets. Since the learning of prior models requires shape patches, whether real or synthetic data, we call this framework semi-supervised learning.

Friedhelm Hamann, Emil Mededovic, Fabian Gülhan et al.

We present an overview of the Spatio-temporal Instance Segmentation (SIS) challenge held in conjunction with the CVPR 2025 Event-based Vision Workshop. The task is to predict accurate pixel-level segmentation masks of defined object classes from spatio-temporally aligned event camera and grayscale camera data. We provide an overview of the task, dataset, challenge details and results. Furthermore, we describe the methods used by the top-5 ranking teams in the challenge. More resources and code of the participants' methods are available here: https://github.com/tub-rip/MouseSIS/blob/main/docs/challenge_results.md

Yuli Wu, Fucheng Liu, Rüveyda Yilmaz et al.

Fréchet Inception Distance (FID), computed with an ImageNet pretrained Inception-v3 network, is widely used as a state-of-the-art evaluation metric for generative models. It assumes that feature vectors from Inception-v3 follow a multivariate Gaussian distribution and calculates the 2-Wasserstein distance based on their means and covariances. While FID effectively measures how closely synthetic data match real data in many image synthesis tasks, the primary goal in biomedical generative models is often to enrich training datasets ideally with corresponding annotations. For this purpose, the gold standard for evaluating generative models is to incorporate synthetic data into downstream task training, such as classification and segmentation, to pragmatically assess its performance. In this paper, we examine cases from retinal imaging modalities, including color fundus photography and optical coherence tomography, where FID and its related metrics misalign with task-specific evaluation goals in classification and segmentation. We highlight the limitations of using various metrics, represented by FID and its variants, as evaluation criteria for these applications and address their potential caveats in broader biomedical imaging modalities and downstream tasks.

Emil Mededovic, Valdy Laurentius, Yuli Wu et al.

We analyze the capabilities of foundation models addressing the tedious task of generating annotations for animal tracking. Annotating a large amount of data is vital and can be a make-or-break factor for the robustness of a tracking model. Robustness is particularly crucial in animal tracking, as accurate tracking over long time horizons is essential for capturing the behavior of animals. However, generating additional annotations using foundation models can be counterproductive, as the quality of the annotations is just as important. Poorly annotated data can introduce noise and inaccuracies, ultimately compromising the performance and accuracy of the trained model. Over-reliance on automated annotations without ensuring precision can lead to diminished results, making careful oversight and quality control essential in the annotation process. Ultimately, we demonstrate that a thoughtful combination of automated annotations and manually annotated data is a valuable strategy, yielding an IDF1 score of 80.8 against blind usage of SAM2 video with an IDF1 score of 65.6.

Rüveyda Yilmaz, Zhu Chen, Yuli Wu et al.

Cell microscopy data are abundant; however, corresponding segmentation annotations remain scarce. Moreover, variations in cell types, imaging devices, and staining techniques introduce significant domain gaps between datasets. As a result, even large, pretrained segmentation models trained on diverse datasets (source datasets) struggle to generalize to unseen datasets (target datasets). To overcome this generalization problem, we propose CellStyle, which improves the segmentation quality of such models without requiring labels for the target dataset, thereby enabling zero-shot adaptation. CellStyle transfers the attributes of an unannotated target dataset, such as texture, color, and noise, to the annotated source dataset. This transfer is performed while preserving the cell shapes of the source images, ensuring that the existing source annotations can still be used while maintaining the visual characteristics of the target dataset. The styled synthetic images with the existing annotations enable the finetuning of a generalist segmentation model for application to the unannotated target data. We demonstrate that CellStyle significantly improves zero-shot cell segmentation performance across diverse datasets by finetuning multiple segmentation models on the style-transferred data. The code will be made publicly available.

Yuli Wu, Yucheng Hu, Suting Miao

We present an object detection based approach to localize handwritten regions from documents, which initially aims to enhance the anonymization during the data transmission. The concatenated fusion of original and preprocessed images containing both printed texts and handwritten notes or signatures are fed into the convolutional neural network, where the bounding boxes are learned to detect the handwriting. Afterwards, the handwritten regions can be processed (e.g. replaced with redacted signatures) to conceal the personally identifiable information (PII). This processing pipeline based on the deep learning network Cascade R-CNN works at 10 fps on a GPU during the inference, which ensures the enhanced anonymization with minimal computational overheads. Furthermore, the impressive generalizability has been empirically showcased: the trained model based on the English-dominant dataset works well on the fictitious unseen invoices, even in Chinese. The proposed approach is also expected to facilitate other tasks such as handwriting recognition and signature verification.

Yuli Wu, Long Chen, Dorit Merhof

As a proposal-free approach, instance segmentation through pixel embedding learning and clustering is gaining more emphasis. Compared with bounding box refinement approaches, such as Mask R-CNN, it has potential advantages in handling complex shapes and dense objects. In this work, we propose a simple, yet highly effective, architecture for object-aware embedding learning. A distance regression module is incorporated into our architecture to generate seeds for fast clustering. At the same time, we show that the features learned by the distance regression module are able to promote the accuracy of learned object-aware embeddings significantly. By simply concatenating features of the distance regression module to the images as inputs of the embedding module, the mSBD scores on the CVPPP Leaf Segmentation Challenge can be further improved by more than 8% compared to the identical set-up without concatenation, yielding the best overall result amongst the leaderboard at CodaLab.