Shu Hu

Yan Ju, Shu Hu, Shan Jia et al.

Despite the development of effective deepfake detectors in recent years, recent studies have demonstrated that biases in the data used to train these detectors can lead to disparities in detection accuracy across different races and genders. This can result in different groups being unfairly targeted or excluded from detection, allowing undetected deepfakes to manipulate public opinion and erode trust in a deepfake detection model. While existing studies have focused on evaluating fairness of deepfake detectors, to the best of our knowledge, no method has been developed to encourage fairness in deepfake detection at the algorithm level. In this work, we make the first attempt to improve deepfake detection fairness by proposing novel loss functions that handle both the setting where demographic information (eg, annotations of race and gender) is available as well as the case where this information is absent. Fundamentally, both approaches can be used to convert many existing deepfake detectors into ones that encourages fairness. Extensive experiments on four deepfake datasets and five deepfake detectors demonstrate the effectiveness and flexibility of our approach in improving deepfake detection fairness. Our code is available at https://github.com/littlejuyan/DF_Fairness.

Shu Hu, Zhenhuan Yang, Xin Wang et al.

Supervised learning models are challenged by the intrinsic complexities of training data such as outliers and minority subpopulations and intentional attacks at inference time with adversarial samples. While traditional robust learning methods and the recent adversarial training approaches are designed to handle each of the two challenges, to date, no work has been done to develop models that are robust with regard to the low-quality training data and the potential adversarial attack at inference time simultaneously. It is for this reason that we introduce Outlier Robust Adversarial Training (ORAT) in this work. ORAT is based on a bi-level optimization formulation of adversarial training with a robust rank-based loss function. Theoretically, we show that the learning objective of ORAT satisfies the $\mathcal{H}$-consistency in binary classification, which establishes it as a proper surrogate to adversarial 0/1 loss. Furthermore, we analyze its generalization ability and provide uniform convergence rates in high probability. ORAT can be optimized with a simple algorithm. Experimental evaluations on three benchmark datasets demonstrate the effectiveness and robustness of ORAT in handling outliers and adversarial attacks. Our code is available at https://github.com/discovershu/ORAT.

Dongxin Ye, Fang Hu, Han Hu et al.

Nucleotide sequences constitute the fundamental genetic basis of biological systems, rendering viral genomic analysis critical for biomedical advancement. Despite progress in biological foundation models, specifically nucleotide foundation models (NFMs), the field lacks a unified standard for viral genomics to facilitate community development and enforce biosecurity constraints. To address this, we introduce ViroBench, the first comprehensive and large-scale benchmark specifically designed for NFMs in viral settings. ViroBench evaluates models across two critical dimensions: biological understanding and latent biosecurity risk, covering 18 diverse scenarios within 4 task types. Extensive evaluation of 66 NFMs across diverse architectures yields three critical conclusions. Firstly, NFMs exhibit a performance degradation in biological understanding under phylogenetic and temporal shifts, indicating weak extrapolation capabilities. Secondly, generation tasks reveal a decoupling between statistical likelihood and biological functional validity, posing latent biosecurity risks. Thirdly, controlled ablation studies reveal that taxonomic diversity in pretraining data outweighs parameter scale. Specifically, a lightweight baseline trained on diverse data achieves a 67.5% performance gain over its original model. Overall, ViroBench provides interpretable, diagnostic evaluations and a reproducible measurement framework for future research on viral nucleotide foundation models. The datasets and code are publicly available at https://github.com/QIANJINYDX/ViroBench.

Yanfei Xiang, Xin Wang, Shu Hu et al.

Reinforcement learning is applied to solve actual complex tasks from high-dimensional, sensory inputs. The last decade has developed a long list of reinforcement learning algorithms. Recent progress benefits from deep learning for raw sensory signal representation. One question naturally arises: how well do they perform concerning different robotic manipulation tasks? Benchmarks use objective performance metrics to offer a scientific way to compare algorithms. In this paper, we present RMBench, the first benchmark for robotic manipulations, which have high-dimensional continuous action and state spaces. We implement and evaluate reinforcement learning algorithms that directly use observed pixels as inputs. We report their average performance and learning curves to show their performance and stability of training. Our study concludes that none of the studied algorithms can handle all tasks well, soft Actor-Critic outperforms most algorithms in average reward and stability, and an algorithm combined with data augmentation may facilitate learning policies. Our code is publicly available at https://github.com/xiangyanfei212/RMBench-2022, including all benchmark tasks and studied algorithms.

Jing Hu, Ziwei Luo, Chengming Feng et al.

Most existing Image-to-Image Translation (I2IT) methods generate images in a single run of a deep learning (DL) model. However, designing such a single-step model is always challenging, requiring a huge number of parameters and easily falling into bad global minimums and overfitting. In this work, we reformulate I2IT as a step-wise decision-making problem via deep reinforcement learning (DRL) and propose a novel framework that performs RL-based I2IT (RL-I2IT). The key feature in the RL-I2IT framework is to decompose a monolithic learning process into small steps with a lightweight model to progressively transform a source image successively to a target image. Considering that it is challenging to handle high dimensional continuous state and action spaces in the conventional RL framework, we introduce meta policy with a new concept Plan to the standard Actor-Critic model, which is of a lower dimension than the original image and can facilitate the actor to generate a tractable high dimensional action. In the RL-I2IT framework, we also employ a task-specific auxiliary learning strategy to stabilize the training process and improve the performance of the corresponding task. Experiments on several I2IT tasks demonstrate the effectiveness and robustness of the proposed method when facing high-dimensional continuous action space problems. Our implementation of the RL-I2IT framework is available at https://github.com/Algolzw/SPAC-Deformable-Registration.

Shu Hu, George H. Chen

We propose a general approach for training survival analysis models that minimizes a worst-case error across all subpopulations that are large enough (occurring with at least a user-specified minimum probability). This approach uses a training loss function that does not know any demographic information to treat as sensitive. Despite this, we demonstrate that our proposed approach often scores better on recently established fairness metrics (without a significant drop in prediction accuracy) compared to various baselines, including ones which directly use sensitive demographic information in their training loss. Our code is available at: https://github.com/discovershu/DRO_COX

Shu Hu, Xin Wang, Siwei Lyu

Recent works have revealed an essential paradigm in designing loss functions that differentiate individual losses vs. aggregate losses. The individual loss measures the quality of the model on a sample, while the aggregate loss combines individual losses/scores over each training sample. Both have a common procedure that aggregates a set of individual values to a single numerical value. The ranking order reflects the most fundamental relation among individual values in designing losses. In addition, decomposability, in which a loss can be decomposed into an ensemble of individual terms, becomes a significant property of organizing losses/scores. This survey provides a systematic and comprehensive review of rank-based decomposable losses in machine learning. Specifically, we provide a new taxonomy of loss functions that follows the perspectives of aggregate loss and individual loss. We identify the aggregator to form such losses, which are examples of set functions. We organize the rank-based decomposable losses into eight categories. Following these categories, we review the literature on rank-based aggregate losses and rank-based individual losses. We describe general formulas for these losses and connect them with existing research topics. We also suggest future research directions spanning unexplored, remaining, and emerging issues in rank-based decomposable losses.

Asmita Yuki Pritha, Jason Xu, Daniel Ding et al.

Deep learning models for COVID-19 detection from chest CT scans generally perform well when the training and test data originate from the same institution, but they often struggle when scans are drawn from multiple centres with differing scanners, imaging protocols, and patient populations. One key reason is that existing methods treat COVID-19 classification as the sole training objective, without accounting for the data source of each scan. As a result, the learned representations tend to be biased toward centres that contribute more training data. To address this, we propose a multi-task learning approach in which the model is trained to predict both the COVID-19 diagnosis and the originating data centre. The two tasks share an EfficientNet-B7 backbone, which encourages the feature extractor to learn representations that hold across all four participating centres. Since the training data is not evenly distributed across sources, we apply a logit-adjusted cross-entropy loss [1] to the source classification head to prevent underrepresented centres from being overlooked. Our pre-processing follows the SSFL framework with KDS [2], selecting eight representative slices per scan. Our method achieves an F1 score of 0.9098 and an AUC-ROC of 0.9647 on a validation set of 308 scans. The code is publicly available at https://github.com/Purdue-M2/-multisource-covid-ct.

Shu Hu, Chun-Hao Liu, Jayanta Dutta et al.

Semi-supervised object detection methods are widely used in autonomous driving systems, where only a fraction of objects are labeled. To propagate information from the labeled objects to the unlabeled ones, pseudo-labels for unlabeled objects must be generated. Although pseudo-labels have proven to improve the performance of semi-supervised object detection significantly, the applications of image-based methods to video frames result in numerous miss or false detections using such generated pseudo-labels. In this paper, we propose a new approach, PseudoProp, to generate robust pseudo-labels by leveraging motion continuity in video frames. Specifically, PseudoProp uses a novel bidirectional pseudo-label propagation approach to compensate for misdetection. A feature-based fusion technique is also used to suppress inference noise. Extensive experiments on the large-scale Cityscapes dataset demonstrate that our method outperforms the state-of-the-art semi-supervised object detection methods by 7.4% on mAP75.

Jing Hu, Qinrui Fan, Shu Hu et al.

In the field of clinical medicine, computed tomography (CT) is an effective medical imaging modality for the diagnosis of various pathologies. Compared with X-ray images, CT images can provide more information, including multi-planar slices and three-dimensional structures for clinical diagnosis. However, CT imaging requires patients to be exposed to large doses of ionizing radiation for a long time, which may cause irreversible physical harm. In this paper, we propose an Uncertainty-aware MedNeRF (UMedNeRF) network based on generated radiation fields. The network can learn a continuous representation of CT projections from 2D X-ray images by obtaining the internal structure and depth information and using adaptive loss weights to ensure the quality of the generated images. Our model is trained on publicly available knee and chest datasets, and we show the results of CT projection rendering with a single X-ray and compare our method with other methods based on generated radiation fields.

Hui Guo, Shu Hu, Xin Wang et al.

AI-synthesized faces are visually challenging to discern from real ones. They have been used as profile images for fake social media accounts, which leads to high negative social impacts. Although progress has been made in developing automatic methods to detect AI-synthesized faces, there is no open platform to study the human performance of AI-synthesized faces detection. In this work, we develop an online platform called Open-eye to study the human performance of AI-synthesized face detection. We describe the design and workflow of the Open-eye in this paper.

Shanmin Yang, Hui Guo, Shu Hu et al.

Deepfake technology poses a significant threat to security and social trust. Although existing detection methods have shown high performance in identifying forgeries within datasets that use the same deepfake techniques for both training and testing, they suffer from sharp performance degradation when faced with cross-dataset scenarios where unseen deepfake techniques are tested. To address this challenge, we propose a Deep Information Decomposition (DID) framework to enhance the performance of Cross-dataset Deepfake Detection (CrossDF). Unlike most existing deepfake detection methods, our framework prioritizes high-level semantic features over specific visual artifacts. Specifically, it adaptively decomposes facial features into deepfake-related and irrelevant information, only using the intrinsic deepfake-related information for real/fake discrimination. Moreover, it optimizes these two kinds of information to be independent with a de-correlation learning module, thereby enhancing the model's robustness against various irrelevant information changes and generalization ability to unseen forgery methods. Our extensive experimental evaluation and comparison with existing state-of-the-art detection methods validate the effectiveness and superiority of the DID framework on cross-dataset deepfake detection.

Hao Chen, Peng Zheng, Xin Wang et al.

As growing usage of social media websites in the recent decades, the amount of news articles spreading online rapidly, resulting in an unprecedented scale of potentially fraudulent information. Although a plenty of studies have applied the supervised machine learning approaches to detect such content, the lack of gold standard training data has hindered the development. Analysing the single data format, either fake text description or fake image, is the mainstream direction for the current research. However, the misinformation in real-world scenario is commonly formed as a text-image pair where the news article/news title is described as text content, and usually followed by the related image. Given the strong ability of learning features without labelled data, contrastive learning, as a self-learning approach, has emerged and achieved success on the computer vision. In this paper, our goal is to explore the constrastive learning in the domain of misinformation identification. We developed a self-learning model and carried out the comprehensive experiments on a public data set named COSMOS. Comparing to the baseline classifier, our model shows the superior performance of non-matched image-text pair detection (approximately 10%) when the training data is insufficient. In addition, we observed the stability for contrsative learning and suggested the use of it offers large reductions in the number of training data, whilst maintaining comparable classification results.

Chengming Feng, Jing Hu, Xin Wang et al.

Controlling the degree of stylization in the Neural Style Transfer (NST) is a little tricky since it usually needs hand-engineering on hyper-parameters. In this paper, we propose the first deep Reinforcement Learning (RL) based architecture that splits one-step style transfer into a step-wise process for the NST task. Our RL-based method tends to preserve more details and structures of the content image in early steps, and synthesize more style patterns in later steps. It is a user-easily-controlled style-transfer method. Additionally, as our RL-based model performs the stylization progressively, it is lightweight and has lower computational complexity than existing one-step Deep Learning (DL) based models. Experimental results demonstrate the effectiveness and robustness of our method.

Jingfu Yang, Peng Huang, Jing Hu et al.

The CNN has achieved excellent results in the automatic classification of medical images. In this study, we propose a novel deep residual 3D attention non-local network (NL-RAN) to classify CT images included COVID-19, common pneumonia, and normal to perform rapid and explainable COVID-19 diagnosis. We built a deep residual 3D attention non-local network that could achieve end-to-end training. The network is embedded with a nonlocal module to capture global information, while a 3D attention module is embedded to focus on the details of the lesion so that it can directly analyze the 3D lung CT and output the classification results. The output of the attention module can be used as a heat map to increase the interpretability of the model. 4079 3D CT scans were included in this study. Each scan had a unique label (novel coronavirus pneumonia, common pneumonia, and normal). The CT scans cohort was randomly split into a training set of 3263 scans, a validation set of 408 scans, and a testing set of 408 scans. And compare with existing mainstream classification methods, such as CovNet, CBAM, ResNet, etc. Simultaneously compare the visualization results with visualization methods such as CAM. Model performance was evaluated using the Area Under the ROC Curve(AUC), precision, and F1-score. The NL-RAN achieved the AUC of 0.9903, the precision of 0.9473, and the F1-score of 0.9462, surpass all the classification methods compared. The heat map output by the attention module is also clearer than the heat map output by CAM. Our experimental results indicate that our proposed method performs significantly better than existing methods. In addition, the first attention module outputs a heat map containing detailed outline information to increase the interpretability of the model. Our experiments indicate that the inference of our model is fast. It can provide real-time assistance with diagnosis.

Yunxu Xie, Shu Hu, Xin Wang et al.

Deep neural networks have been demonstrated to be vulnerable to adversarial attacks: subtle perturbation can completely change the prediction result. Existing adversarial attacks on object detection focus on attacking anchor-based detectors, which may not work well for anchor-free detectors. In this paper, we propose the first adversarial attack dedicated to anchor-free detectors. It is a category-wise attack that attacks important pixels of all instances of a category simultaneously. Our attack manifests in two forms, sparse category-wise attack (SCA) and dense category-wise attack (DCA), that minimize the $L_0$ and $L_\infty$ norm-based perturbations, respectively. For DCA, we present three variants, DCA-G, DCA-L, and DCA-S, that select a global region, a local region, and a semantic region, respectively, to attack. Our experiments on large-scale benchmark datasets including PascalVOC, MS-COCO, and MS-COCO Keypoints indicate that our proposed methods achieve state-of-the-art attack performance and transferability on both object detection and human pose estimation tasks.

Justin Li, Daniel Ding, Asmita Yuki Pritha et al.

Automated diagnosis from chest CT has improved considerably with deep learning, but models trained on skewed datasets tend to perform unevenly across patient demographics. However, the situation is worse than simple demographic bias. In clinical data, class imbalance and group underrepresentation often coincide, creating compound failure modes that neither standard rebalancing nor fairness corrections can fix alone. We introduce a two-level objective that targets both axes of this problem. Logit-adjusted cross-entropy loss operates at the sample level, shifting decision margins by class frequency with provable consistency guarantees. Conditional Value at Risk aggregation operates at the group level, directing optimization pressure toward whichever demographic group currently has the higher loss. We evaluate on the Fair Disease Diagnosis benchmark using a 3D ResNet-18 pretrained on Kinetics-400, classifying CT volumes into Adenocarcinoma, Squamous Cell Carcinoma, COVID-19, and Normal groups with patient sex annotations. The training set illustrates the compound problem concretely: squamous cell carcinoma has 84 samples total, 5 of them female. The combined loss reaches a gender-averaged macro F1 of 0.8403 with a fairness gap of 0.0239, a 13.3% improvement in score and 78% reduction in demographic disparity over the baseline. Ablations show that each component alone falls short. The code is publicly available at https://github.com/Purdue-M2/Fair-Disease-Diagnosis.

Li Lin, Neeraj Gupta, Yue Zhang et al.

The rapid advancement of Large AI Models (LAIMs), particularly diffusion models and large language models, has marked a new era where AI-generated multimedia is increasingly integrated into various aspects of daily life. Although beneficial in numerous fields, this content presents significant risks, including potential misuse, societal disruptions, and ethical concerns. Consequently, detecting multimedia generated by LAIMs has become crucial, with a marked rise in related research. Despite this, there remains a notable gap in systematic surveys that focus specifically on detecting LAIM-generated multimedia. Addressing this, we provide the first survey to comprehensively cover existing research on detecting multimedia (such as text, images, videos, audio, and multimodal content) created by LAIMs. Specifically, we introduce a novel taxonomy for detection methods, categorized by media modality, and aligned with two perspectives: pure detection (aiming to enhance detection performance) and beyond detection (adding attributes like generalizability, robustness, and interpretability to detectors). Additionally, we have presented a brief overview of generation mechanisms, public datasets, online detection tools, and evaluation metrics to provide a valuable resource for researchers and practitioners in this field. Most importantly, we offer a focused analysis from a social media perspective to highlight their broader societal impact. Furthermore, we identify current challenges in detection and propose directions for future research that address unexplored, ongoing, and emerging issues in detecting multimedia generated by LAIMs. Our aim for this survey is to fill an academic gap and contribute to global AI security efforts, helping to ensure the integrity of information in the digital realm. The project link is https://github.com/Purdue-M2/Detect-LAIM-generated-Multimedia-Survey.

Li Lin, Xinan He, Yan Ju et al.

Although effective deepfake detection models have been developed in recent years, recent studies have revealed that these models can result in unfair performance disparities among demographic groups, such as race and gender. This can lead to particular groups facing unfair targeting or exclusion from detection, potentially allowing misclassified deepfakes to manipulate public opinion and undermine trust in the model. The existing method for addressing this problem is providing a fair loss function. It shows good fairness performance for intra-domain evaluation but does not maintain fairness for cross-domain testing. This highlights the significance of fairness generalization in the fight against deepfakes. In this work, we propose the first method to address the fairness generalization problem in deepfake detection by simultaneously considering features, loss, and optimization aspects. Our method employs disentanglement learning to extract demographic and domain-agnostic forgery features, fusing them to encourage fair learning across a flattened loss landscape. Extensive experiments on prominent deepfake datasets demonstrate our method's effectiveness, surpassing state-of-the-art approaches in preserving fairness during cross-domain deepfake detection. The code is available at https://github.com/Purdue-M2/Fairness-Generalization

Lei Zhang, Hao Chen, Shu Hu et al.

Generative adversarial networks (GANs) have remarkably advanced in diverse domains, especially image generation and editing. However, the misuse of GANs for generating deceptive images, such as face replacement, raises significant security concerns, which have gained widespread attention. Therefore, it is urgent to develop effective detection methods to distinguish between real and fake images. Current research centers around the application of transfer learning. Nevertheless, it encounters challenges such as knowledge forgetting from the original dataset and inadequate performance when dealing with imbalanced data during training. To alleviate this issue, this paper introduces a novel GAN-generated image detection algorithm called X-Transfer, which enhances transfer learning by utilizing two neural networks that employ interleaved parallel gradient transmission. In addition, we combine AUC loss and cross-entropy loss to improve the model's performance. We carry out comprehensive experiments on multiple facial image datasets. The results show that our model outperforms the general transferring approach, and the best metric achieves 99.04%, which is increased by approximately 10%. Furthermore, we demonstrate excellent performance on non-face datasets, validating its generality and broader application prospects.

Ting Yu Tsai, Liangqiao Gui, Yineng Chen et al.

Deep learning models have achieved significant success in segmenting cardiovascular structures, but there is a growing need to improve their generalization and robustness. Current methods often face challenges such as overfitting and limited accuracy, largely due to their reliance on large annotated datasets and limited optimization techniques. This paper introduces the UU-Mamba model, an extension of the U-Mamba architecture, designed to address these challenges in both cardiac and vascular segmentation. By incorporating Sharpness-Aware Minimization (SAM), the model enhances generalization by seeking flatter minima in the loss landscape. Additionally, we propose an uncertainty-aware loss function that integrates region-based, distribution-based, and pixel-based components, improving segmentation accuracy by capturing both local and global features. We expand our evaluations on the ImageCAS (coronary artery) and Aorta (aortic branches and zones) datasets, which present more complex segmentation challenges than the ACDC dataset (left and right ventricles) used in prior work, showcasing the model's adaptability and resilience. Our results confirm UU-Mamba's superior performance compared to leading models such as TransUNet, Swin-Unet, nnUNet, and nnFormer. We also provide a more in-depth assessment of the model's robustness and segmentation accuracy through extensive experiments.

Santosh, Li Lin, Irene Amerini et al.

Diffusion models (DMs) have revolutionized image generation, producing high-quality images with applications spanning various fields. However, their ability to create hyper-realistic images poses significant challenges in distinguishing between real and synthetic content, raising concerns about digital authenticity and potential misuse in creating deepfakes. This work introduces a robust detection framework that integrates image and text features extracted by CLIP model with a Multilayer Perceptron (MLP) classifier. We propose a novel loss that can improve the detector's robustness and handle imbalanced datasets. Additionally, we flatten the loss landscape during the model training to improve the detector's generalization capabilities. The effectiveness of our method, which outperforms traditional detection techniques, is demonstrated through extensive experiments, underscoring its potential to set a new state-of-the-art approach in DM-generated image detection. The code is available at https://github.com/Purdue-M2/Robust_DM_Generated_Image_Detection.

Xin Wang, Xiaoyu Liu, Peng Huang et al.

Medical Image Foundation Models have proven to be powerful tools for mask prediction across various datasets. However, accurately assessing the uncertainty of their predictions remains a significant challenge. To address this, we propose a new model, U-MedSAM, which integrates the MedSAM model with an uncertainty-aware loss function and the Sharpness-Aware Minimization (SharpMin) optimizer. The uncertainty-aware loss function automatically combines region-based, distribution-based, and pixel-based loss designs to enhance segmentation accuracy and robustness. SharpMin improves generalization by finding flat minima in the loss landscape, thereby reducing overfitting. Our method was evaluated in the CVPR24 MedSAM on Laptop challenge, where U-MedSAM demonstrated promising performance.

Li Lin, Yamini Sri Krubha, Zhenhuan Yang et al.

In the realm of medical imaging, particularly for COVID-19 detection, deep learning models face substantial challenges such as the necessity for extensive computational resources, the paucity of well-annotated datasets, and a significant amount of unlabeled data. In this work, we introduce the first lightweight detector designed to overcome these obstacles, leveraging a frozen CLIP image encoder and a trainable multilayer perception (MLP). Enhanced with Conditional Value at Risk (CVaR) for robustness and a loss landscape flattening strategy for improved generalization, our model is tailored for high efficacy in COVID-19 detection. Furthermore, we integrate a teacher-student framework to capitalize on the vast amounts of unlabeled data, enabling our model to achieve superior performance despite the inherent data limitations. Experimental results on the COV19-CT-DB dataset demonstrate the effectiveness of our approach, surpassing baseline by up to 10.6% in `macro' F1 score in supervised learning. The code is available at https://github.com/Purdue-M2/COVID-19_Detection_M2_PURDUE.

Shu Hu, George H. Chen

We propose a general approach for encouraging fairness in survival analysis models based on minimizing a worst-case error across all subpopulations that occur with at least a user-specified probability. This approach can be used to convert many existing survival analysis models into ones that simultaneously encourage fairness, without requiring the user to specify which attributes or features to treat as sensitive in the training loss function. From a technical standpoint, our approach applies recent developments of distributionally robust optimization (DRO) to survival analysis. The complication is that existing DRO theory uses a training loss function that decomposes across contributions of individual data points, i.e., any term that shows up in the loss function depends only on a single training point. This decomposition does not hold for commonly used survival loss functions, including for the Cox proportional hazards model, its deep neural network variants, and many other recently developed models that use loss functions involving ranking or similarity score calculations. We address this technical hurdle using a sample splitting strategy. We demonstrate our sample splitting DRO approach by using it to create fair versions of a diverse set of existing survival analysis models including the Cox model (and its deep variant DeepSurv), the discrete-time model DeepHit, and the neural ODE model SODEN. We also establish a finite-sample theoretical guarantee to show what our sample splitting DRO loss converges to. For the Cox model, we further derive an exact DRO approach that does not use sample splitting. For all the models that we convert into DRO variants, we show that the DRO variants often score better on recently established fairness metrics (without incurring a significant drop in accuracy) compared to existing survival analysis fairness regularization techniques.

Peng Huang, Shu Hu, Bo Peng et al.

MedSAM, a medical foundation model derived from the SAM architecture, has demonstrated notable success across diverse medical domains. However, its clinical application faces two major challenges: the dependency on labor-intensive manual prompt generation, which imposes a significant burden on clinicians, and the absence of semantic labeling in the generated segmentation masks for organs or lesions, limiting its practicality for non-expert users. To address these limitations, we propose AutoMedSAM, an end-to-end framework derived from SAM, designed to enhance usability and segmentation performance. AutoMedSAM retains MedSAM's image encoder and mask decoder structure while introducing a novel diffusion-based class prompt encoder. The diffusion-based encoder employs a dual-decoder structure to collaboratively generate prompt embeddings guided by sparse and dense prompt definitions. These embeddings enhance the model's ability to understand and process clinical imagery autonomously. With this encoder, AutoMedSAM leverages class prompts to embed semantic information into the model's predictions, transforming MedSAM's semi-automated pipeline into a fully automated workflow. Furthermore, AutoMedSAM employs an uncertainty-aware joint optimization strategy during training to effectively inherit MedSAM's pre-trained knowledge while improving generalization by integrating multiple loss functions. Experimental results across diverse datasets demonstrate that AutoMedSAM achieves superior performance while broadening its applicability to both clinical settings and non-expert users. Code is available at https://github.com/HP-ML/AutoPromptMedSAM.git.

Qingxiao Li, Lifeng Xu, QingLi Wang et al.

We present S1-VL, a multimodal reasoning model for scientific domains that natively supports two complementary reasoning paradigms: Scientific Reasoning, which relies on structured chain-of-thought, and Thinking-with-Images, which enables the model to actively manipulate images through Python code execution during reasoning. In the Thinking-with-Images mode, the model generates and executes image-processing code in a sandbox environment, obtains intermediate visual results, and continues reasoning in a multi-turn iterative manner. This design is particularly effective for challenging scenarios such as high-resolution scientific chart interpretation, microscopic image understanding, and geometry-assisted reasoning. To construct the training data, we collect scientific multimodal datasets spanning six disciplines: mathematics, physics, chemistry, astronomy, geography, and biology. We further develop a six-dimensional quality filtering framework for reasoning trajectories. To mitigate redundant, ineffective, and erroneous visual operations commonly found in existing datasets, we propose a multi-stage filtering pipeline together with an adaptive data routing strategy. This strategy converts samples with low visual information gain into pure Reasoning-mode data, enabling the model to learn when image operations are truly necessary. S1-VL is trained through a four-stage progressive pipeline: scientific multimodal SFT, Thinking-with-Images cold-start SFT, and two stages of reinforcement learning with SAPO. We build S1-VL-32B on top of Qwen3-VL-32B-Thinking and evaluate it on 13 benchmarks. Experimental results show that S1-VL-32B achieves state-of-the-art performance on all five Thinking-with-Images benchmarks, including HRBench-4K, HRBench-8K, MME-RealWorld-CN, MME-RealWorld-Lite, and V*, and outperforms compared systems on scientific reasoning benchmarks such as Physics and VRSBench.

Mingyang Wu, Li Lin, Wenbin Zhang et al.

The Area Under the ROC Curve (AUC) is a key metric for classification, especially under class imbalance, with growing research focus on optimizing AUC over accuracy in applications like medical image analysis and deepfake detection. This leads to fairness in AUC optimization becoming crucial as biases can impact protected groups. While various fairness mitigation techniques exist, fairness considerations in AUC optimization remain in their early stages, with most research focusing on improving AUC fairness under the assumption of clean protected groups. However, these studies often overlook the impact of noisy protected groups, leading to fairness violations in practice. To address this, we propose the first robust AUC fairness approach under noisy protected groups with fairness theoretical guarantees using distributionally robust optimization. Extensive experiments on tabular and image datasets show that our method outperforms state-of-the-art approaches in preserving AUC fairness. The code is in https://github.com/Purdue-M2/AUC_Fairness_with_Noisy_Groups.

Yamini Sri Krubha, Aryana Hou, Braden Vester et al.

Deepfakes, created using advanced AI techniques such as Variational Autoencoder and Generative Adversarial Networks, have evolved from research and entertainment applications into tools for malicious activities, posing significant threats to digital trust. Current deepfake detection techniques have evolved from CNN-based methods focused on local artifacts to more advanced approaches using vision transformers and multimodal models like CLIP, which capture global anomalies and improve cross-domain generalization. Despite recent progress, state-of-the-art deepfake detectors still face major challenges in handling distribution shifts from emerging generative models and addressing severe class imbalance between authentic and fake samples in deepfake datasets, which limits their robustness and detection accuracy. To address these challenges, we propose a framework that combines dynamic loss reweighting and ranking-based optimization, which achieves superior generalization and performance under imbalanced dataset conditions. The code is available at https://github.com/Purdue-M2/SP_CUP.

Aryana Hou, Li Lin, Justin Li et al.

Generative AI models have substantially improved the realism of synthetic media, yet their misuse through sophisticated DeepFakes poses significant risks. Despite recent advances in deepfake detection, fairness remains inadequately addressed, enabling deepfake markers to exploit biases against specific populations. While previous studies have emphasized group-level fairness, individual fairness (i.e., ensuring similar predictions for similar individuals) remains largely unexplored. In this work, we identify for the first time that the original principle of individual fairness fundamentally fails in the context of deepfake detection, revealing a critical gap previously unexplored in the literature. To mitigate it, we propose the first generalizable framework that can be integrated into existing deepfake detectors to enhance individual fairness and generalization. Extensive experiments conducted on leading deepfake datasets demonstrate that our approach significantly improves individual fairness while maintaining robust detection performance, outperforming state-of-the-art methods. The code is available at https://github.com/Purdue-M2/Individual-Fairness-Deepfake-Detection.

Philip R. Liu, Sparsh Bansal, Jimmy Dinh et al.

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to medical imaging remains challenging due to hallucinations, limited interpretability, and insufficient domain-specific medical knowledge, which can potentially reduce clinical accuracy. Although recent approaches combining imaging models with LLM reasoning have improved reporting, they typically rely on a single generalist agent, restricting their capacity to emulate the diverse and complex reasoning found in multidisciplinary medical teams. To address these limitations, we propose MedChat, a multi-agent diagnostic framework and platform that combines specialized vision models with multiple role-specific LLM agents, all coordinated by a director agent. This design enhances reliability, reduces hallucination risk, and enables interactive diagnostic reporting through an interface tailored for clinical review and educational use. Code available at https://github.com/Purdue-M2/MedChat.

Jing Hu, Kaiwei Yu, Hongjiang Xian et al.

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but are limited by computational efficiency. Although deep learning approaches have significantly improved registration speed and accuracy, they often lack flexibility and generalizability across different datasets and tasks. In recent years, foundation models have emerged as a promising direction, leveraging large and diverse datasets to learn universal features and transformation patterns for image registration, thus demonstrating strong cross-task transferability. However, these models still face challenges in generalization and robustness when encountering novel anatomical structures, varying imaging conditions, or unseen modalities. To address these limitations, this paper incorporates Sharpness-Aware Minimization (SAM) into foundation models to enhance their generalization and robustness in medical image registration. By optimizing the flatness of the loss landscape, SAM improves model stability across diverse data distributions and strengthens its ability to handle complex clinical scenarios. Experimental results show that foundation models integrated with SAM achieve significant improvements in cross-dataset registration performance, offering new insights for the advancement of medical image registration technology. Our code is available at https://github.com/Promise13/fm_sam}{https://github.com/Promise13/fm\_sam.

Xiaoqiong Liu, Yunhe Feng, Shu Hu et al.

The robustness of unmanned aerial vehicle (UAV) tracking is crucial in many tasks like surveillance and robotics. Despite its importance, little attention is paid to the performance of UAV trackers under common corruptions due to lack of a dedicated platform. Addressing this, we propose UAV-C, a large-scale benchmark for assessing robustness of UAV trackers under common corruptions. Specifically, UAV-C is built upon two popular UAV datasets by introducing 18 common corruptions from 4 representative categories including adversarial, sensor, blur, and composite corruptions in different levels. Finally, UAV-C contains more than 10K sequences. To understand the robustness of existing UAV trackers against corruptions, we extensively evaluate 12 representative algorithms on UAV-C. Our study reveals several key findings: 1) Current trackers are vulnerable to corruptions, indicating more attention needed in enhancing the robustness of UAV trackers; 2) When accompanying together, composite corruptions result in more severe degradation to trackers; and 3) While each tracker has its unique performance profile, some trackers may be more sensitive to specific corruptions. By releasing UAV-C, we hope it, along with comprehensive analysis, serves as a valuable resource for advancing the robustness of UAV tracking against corruption. Our UAV-C will be available at https://github.com/Xiaoqiong-Liu/UAV-C.

Mei Qiu, Wei Lin, Stanley Chien et al.

Vehicle weaving on highways contributes to traffic congestion, raises safety issues, and underscores the need for sophisticated traffic management systems. Current tools are inadequate in offering precise and comprehensive data on lane-specific weaving patterns. This paper introduces an innovative method for collecting non-overlapping video data in weaving zones, enabling the generation of quantitative insights into lane-specific weaving behaviors. Our experimental results confirm the efficacy of this approach, delivering critical data that can assist transportation authorities in enhancing traffic control and roadway infrastructure.

Dat Le, Khoa Nguyen, Xin Wang et al.

Recent advances in generative AI have democratized video creation at scale. AI-generated videos, including partially manipulated clips across visual and audio channels, pose escalating risks of semantic distortion and misuse, which motivates the need for reliable detection tools. Most existing AI-generated video detectors remain limited by single- or partial-modality of data modeling and the lack of fine-grained temporal forgery localization. To address these challenges, our primary novelty introduces a core architecture that jointly integrates an LMM semantic branch with a spatio-temporal (ST) visual branch and a multi-scale partial-spoof (PS) audio branch. This multi-modal approach enables simultaneous detection and fine-grained temporal localization of partially manipulated AI-generated video forgeries. Extensive experiments show that this approach outperforms existing state-of-the-art methods.

Feng Ding, Wenhui Yi, Yunpeng Zhou et al.

Fairness is a core element in the trustworthy deployment of deepfake detection models, especially in the field of digital identity security. Biases in detection models toward different demographic groups, such as gender and race, may lead to systemic misjudgments, exacerbating the digital divide and social inequities. However, current fairness-enhanced detectors often improve fairness at the cost of detection accuracy. To address this challenge, we propose a dual-mechanism collaborative optimization framework. Our proposed method innovatively integrates structural fairness decoupling and global distribution alignment: decoupling channels sensitive to demographic groups at the model architectural level, and subsequently reducing the distance between the overall sample distribution and the distributions corresponding to each demographic group at the feature level. Experimental results demonstrate that, compared with other methods, our framework improves both inter-group and intra-group fairness while maintaining overall detection accuracy across domains.

Jing Hu, Chengming Feng, Shu Hu et al.

Arbitrary style transfer aims to apply the style of any given artistic image to another content image. Still, existing deep learning-based methods often require significant computational costs to generate diverse stylized results. Motivated by this, we propose a novel reinforcement learning-based framework for arbitrary style transfer RLMiniStyler. This framework leverages a unified reinforcement learning policy to iteratively guide the style transfer process by exploring and exploiting stylization feedback, generating smooth sequences of stylized results while achieving model lightweight. Furthermore, we introduce an uncertainty-aware multi-task learning strategy that automatically adjusts loss weights to adapt to the content and style balance requirements at different training stages, thereby accelerating model convergence. Through a series of experiments across image various resolutions, we have validated the advantages of RLMiniStyler over other state-of-the-art methods in generating high-quality, diverse artistic image sequences at a lower cost. Codes are available at https://github.com/fengxiaoming520/RLMiniStyler.

Peng Huang, Shu Hu, Bo Peng et al.

Current medical image classification efforts mainly aim for higher average performance, often neglecting the balance between different classes. This can lead to significant differences in recognition accuracy between classes and obvious recognition weaknesses. Without the support of massive data, deep learning faces challenges in fine-grained classification of fatty liver. In this paper, we propose an innovative deep learning framework that combines feature decoupling and adaptive adversarial training. Firstly, we employ two iteratively compressed decouplers to supervised decouple common features and specific features related to fatty liver in abdominal ultrasound images. Subsequently, the decoupled features are concatenated with the original image after transforming the color space and are fed into the classifier. During adversarial training, we adaptively adjust the perturbation and balance the adversarial strength by the accuracy of each class. The model will eliminate recognition weaknesses by correctly classifying adversarial samples, thus improving recognition robustness. Finally, the accuracy of our method improved by 4.16%, achieving 82.95%. As demonstrated by extensive experiments, our method is a generalized learning framework that can be directly used to eliminate the recognition weaknesses of any classifier while improving its average performance. Code is available at https://github.com/HP-ML/MICCAI2024.

Li Lin, Santosh, Mingyang Wu et al.

AI-generated faces have enriched human life, such as entertainment, education, and art. However, they also pose misuse risks. Therefore, detecting AI-generated faces becomes crucial, yet current detectors show biased performance across different demographic groups. Mitigating biases can be done by designing algorithmic fairness methods, which usually require demographically annotated face datasets for model training. However, no existing dataset encompasses both demographic attributes and diverse generative methods simultaneously, which hinders the development of fair detectors for AI-generated faces. In this work, we introduce the AI-Face dataset, the first million-scale demographically annotated AI-generated face image dataset, including real faces, faces from deepfake videos, and faces generated by Generative Adversarial Networks and Diffusion Models. Based on this dataset, we conduct the first comprehensive fairness benchmark to assess various AI face detectors and provide valuable insights and findings to promote the future fair design of AI face detectors. Our AI-Face dataset and benchmark code are publicly available at https://github.com/Purdue-M2/AI-Face-FairnessBench

Li Lin, Sarah Papabathini, Xin Wang et al.

Human affective behavior analysis aims to delve into human expressions and behaviors to deepen our understanding of human emotions. Basic expression categories (EXPR) and Action Units (AUs) are two essential components in this analysis, which categorize emotions and break down facial movements into elemental units, respectively. Despite advancements, existing approaches in expression classification and AU detection often necessitate complex models and substantial computational resources, limiting their applicability in everyday settings. In this work, we introduce the first lightweight framework adept at efficiently tackling both expression classification and AU detection. This framework employs a frozen CLIP image encoder alongside a trainable multilayer perceptron (MLP), enhanced with Conditional Value at Risk (CVaR) for robustness and a loss landscape flattening strategy for improved generalization. Experimental results on the Aff-wild2 dataset demonstrate superior performance in comparison to the baseline while maintaining minimal computational demands, offering a practical solution for affective behavior analysis. The code is available at https://github.com/Purdue-M2/Affective_Behavior_Analysis_M2_PURDUE

Peng Huang, Yiming Wang, Yineng Chen et al.

Echocardiography plays an important role in the screening and diagnosis of cardiovascular diseases. However, automated intelligent analysis of echocardiographic data remains challenging due to complex cardiac dynamics and strong view heterogeneity. In recent years, visual language models (VLM) have opened a new avenue for building ultrasound understanding systems for clinical decision support. Nevertheless, most existing methods formulate this task as a direct mapping from video and question to answer, making them vulnerable to template shortcuts and spurious explanations. To address these issues, we propose EchoTrust, an evidence-driven Actor-Verifier framework for trustworthy reasoning in echocardiography VLM-based agents. EchoTrust produces a structured intermediate representation that is subsequently analyzed by distinct roles, enabling more reliable and interpretable decision-making for high-stakes clinical applications.

Bing Fan, Shu Hu, Feng Ding

DeepFake, an AI technology for creating facial forgeries, has garnered global attention. Amid such circumstances, forensics researchers focus on developing defensive algorithms to counter these threats. In contrast, there are techniques developed for enhancing the aggressiveness of DeepFake, e.g., through anti-forensics attacks, to disrupt forensic detectors. However, such attacks often sacrifice image visual quality for improved undetectability. To address this issue, we propose a method to generate novel adversarial sharpening masks for launching black-box anti-forensics attacks. Unlike many existing arts, with such perturbations injected, DeepFakes could achieve high anti-forensics performance while exhibiting pleasant sharpening visual effects. After experimental evaluations, we prove that the proposed method could successfully disrupt the state-of-the-art DeepFake detectors. Besides, compared with the images processed by existing DeepFake anti-forensics methods, the visual qualities of anti-forensics DeepFakes rendered by the proposed method are significantly refined.

Hang Yang, Hao Chen, Hui Guo et al.

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face significant challenges in medical question answering, particularly in understanding domain-specific terminologies and performing complex reasoning. These limitations undermine their effectiveness in critical medical applications. To address these issues, we propose a novel approach incorporating similar case generation within a multi-agent medical question-answering (MedQA) system. Specifically, we leverage the Llama3.1:70B model, a state-of-the-art LLM, in a multi-agent architecture to enhance performance on the MedQA dataset using zero-shot learning. Our method capitalizes on the model's inherent medical knowledge and reasoning capabilities, eliminating the need for additional training data. Experimental results show substantial performance gains over existing benchmark models, with improvements of 7% in both accuracy and F1-score across various medical QA tasks. Furthermore, we examine the model's interpretability and reliability in addressing complex medical queries. This research not only offers a robust solution for medical question answering but also establishes a foundation for broader applications of LLMs in the medical domain.

Yicui Peng, Hao Chen, Chingsheng Lin et al.

Providing explanations within the recommendation system would boost user satisfaction and foster trust, especially by elaborating on the reasons for selecting recommended items tailored to the user. The predominant approach in this domain revolves around generating text-based explanations, with a notable emphasis on applying large language models (LLMs). However, refining LLMs for explainable recommendations proves impractical due to time constraints and computing resource limitations. As an alternative, the current approach involves training the prompt rather than the LLM. In this study, we developed a model that utilizes the ID vectors of user and item inputs as prompts for GPT-2. We employed a joint training mechanism within a multi-task learning framework to optimize both the recommendation task and explanation task. This strategy enables a more effective exploration of users' interests, improving recommendation effectiveness and user satisfaction. Through the experiments, our method achieving 1.59 DIV, 0.57 USR and 0.41 FCR on the Yelp, TripAdvisor and Amazon dataset respectively, demonstrates superior performance over four SOTA methods in terms of explainability evaluation metric. In addition, we identified that the proposed model is able to ensure stable textual quality on the three public datasets.

Hainan Ren, Li Lin, Chun-Hao Liu et al.

AI-synthesized voice technology has the potential to create realistic human voices for beneficial applications, but it can also be misused for malicious purposes. While existing AI-synthesized voice detection models excel in intra-domain evaluation, they face challenges in generalizing across different domains, potentially becoming obsolete as new voice generators emerge. Current solutions use diverse data and advanced machine learning techniques (e.g., domain-invariant representation, self-supervised learning), but are limited by predefined vocoders and sensitivity to factors like background noise and speaker identity. In this work, we introduce an innovative disentanglement framework aimed at extracting domain-agnostic artifact features related to vocoders. Utilizing these features, we enhance model learning in a flat loss landscape, enabling escape from suboptimal solutions and improving generalization. Extensive experiments on benchmarks show our approach outperforms state-of-the-art methods, achieving up to 5.12% improvement in the equal error rate metric in intra-domain and 7.59% in cross-domain evaluations.

Tiewen Chen, Shanmin Yang, Shu Hu et al.

Recent studies on deepfake detection have achieved promising results when training and testing faces are from the same dataset. However, their results severely degrade when confronted with forged samples that the model has not yet seen during training. In this paper, deepfake data to help detect deepfakes. this paper present we put a new insight into diffusion model-based data augmentation, and propose a Masked Conditional Diffusion Model (MCDM) for enhancing deepfake detection. It generates a variety of forged faces from a masked pristine one, encouraging the deepfake detection model to learn generic and robust representations without overfitting to special artifacts. Extensive experiments demonstrate that forgery images generated with our method are of high quality and helpful to improve the performance of deepfake detection models.

Mei Qiu, Wei Lin, Lauren Ann Christopher et al.

In the US, thousands of Pan, Tilt, and Zoom (PTZ) traffic cameras monitor highway conditions. There is a great interest in using these highway cameras to gather valuable road traffic data to support traffic analysis and decision-making for highway safety and efficient traffic management. However, there are too many cameras for a few human traffic operators to effectively monitor, so a fully automated solution is desired. This paper introduces a novel system that learns the locations of highway lanes and traffic directions from these camera feeds automatically. It collects real-time, lane-specific traffic data continuously, even adjusting for changes in camera angle or zoom. This facilitates efficient traffic analysis, decision-making, and improved highway safety.

Chengxu Wu, Qinrui Fan, Shu Hu et al.

An important development direction in the Single-Image Super-Resolution (SISR) algorithms is to improve the efficiency of the algorithms. Recently, efficient Super-Resolution (SR) research focuses on reducing model complexity and improving efficiency through improved deep small kernel convolution, leading to a small receptive field. The large receptive field obtained by large kernel convolution can significantly improve image quality, but the computational cost is too high. To improve the reconstruction details of efficient super-resolution reconstruction, we propose a Symmetric Visual Attention Network (SVAN) by applying large receptive fields. The SVAN decomposes a large kernel convolution into three different combinations of convolution operations and combines them with an attention mechanism to form a Symmetric Large Kernel Attention Block (SLKAB), which forms a symmetric attention block with a bottleneck structure by the size of the receptive field in the convolution combination to extract depth features effectively as the basic component of the SVAN. Our network gets a large receptive field while minimizing the number of parameters and improving the perceptual ability of the model. The experimental results show that the proposed SVAN can obtain high-quality super-resolution reconstruction results using only about 30% of the parameters of existing SOTA methods.

Hao Chen, Hui Guo, Baochen Hu et al.

The rapid growth of social media has resulted in an explosion of online news content, leading to a significant increase in the spread of misleading or false information. While machine learning techniques have been widely applied to detect fake news, the scarcity of labeled datasets remains a critical challenge. Misinformation frequently appears as paired text and images, where a news article or headline is accompanied by a related visuals. In this paper, we introduce a self-learning multimodal model for fake news classification. The model leverages contrastive learning, a robust method for feature extraction that operates without requiring labeled data, and integrates the strengths of Large Language Models (LLMs) to jointly analyze both text and image features. LLMs are excel at this task due to their ability to process diverse linguistic data drawn from extensive training corpora. Our experimental results on a public dataset demonstrate that the proposed model outperforms several state-of-the-art classification approaches, achieving over 85% accuracy, precision, recall, and F1-score. These findings highlight the model's effectiveness in tackling the challenges of multimodal fake news detection.

Xin Wang, Yineng Chen, Shu Hu et al.

Neural Radiance Fields (NeRF), as a pioneering technique in computer vision, offer great potential to revolutionize medical imaging by synthesizing three-dimensional representations from the projected two-dimensional image data. However, they face unique challenges when applied to medical applications. This paper presents a comprehensive examination of applications of NeRFs in medical imaging, highlighting four imminent challenges, including fundamental imaging principles, inner structure requirement, object boundary definition, and color density significance. We discuss current methods on different organs and discuss related limitations. We also review several datasets and evaluation metrics and propose several promising directions for future research.