Zexi Wu

Jing Dai, Chen Wu, Ming Wu et al.

Recent advances in multimodal learning have significantly improved cancer survival risk prediction. However, the joint prognostic potential of protein markers and histopathology images remains underexplored, largely due to the high cost and limited availability of protein expression profiling. To address this challenge, we propose HGP-Mamba, a Mamba-based multimodal framework that efficiently integrates histological with generated protein features for survival risk prediction. Specifically, we introduce a protein feature extractor (PFE) that leverages pretrained foundation models to derive high-throughput protein embeddings directly from Whole Slide Images (WSIs), enabling data-efficient incorporation of molecular information. Together with histology embeddings that capture morphological patterns, we further introduce the Local Interaction-aware Mamba (LiAM) for fine-grained feature interaction and the Global Interaction-enhanced Mamba (GiEM) to promote holistic modality fusion at the slide level, thus capture complex cross-modal dependencies. Experiments on four public cancer datasets demonstrate that HGP-Mamba achieves state-of-the-art performance while maintaining superior computational efficiency compared with existing methods. Our source code is publicly available at https://github.com/Daijing-ai/HGP-Mamba.git.

Xian Zhang, Zexi Wu, Zinuo Li et al.

Understanding long-form videos remains a significant challenge for vision--language models (VLMs) due to their extensive temporal length and high information density. Most current multimodal large language models (MLLMs) rely on uniform sampling, which often overlooks critical moments, leading to incorrect responses to queries. In parallel, many keyframe selection approaches impose rigid temporal spacing: once a frame is chosen, an exclusion window suppresses adjacent timestamps to reduce redundancy. While effective at limiting overlap, this strategy frequently misses short, fine-grained cues near important events. Other methods instead emphasize visual diversity but neglect query relevance. We propose AdaRD-Key, a training-free keyframe sampling module for query-driven long-form video understanding. AdaRD-Key maximizes a unified Relevance--Diversity Max-Volume (RD-MV) objective, combining a query-conditioned relevance score with a log-determinant diversity component to yield informative yet non-redundant frames. To handle broad queries with weak alignment to the video, AdaRD-Key employs a lightweight relevance-aware gating mechanism; when the relevance distribution indicates weak alignment, the method seamlessly shifts into a diversity-only mode, enhancing coverage without additional supervision. Our pipeline is training-free, computationally efficient (running in real time on a single GPU), and compatible with existing VLMs in a plug-and-play manner. Extensive experiments on LongVideoBench and Video-MME demonstrate state-of-the-art performance, particularly on long-form videos. Code available at https://github.com/Xian867/AdaRD-Key.

Zexi Wu, Qinghe Wang, Jing Dai et al.

Achieving semantic alignment across diverse video generation conditions remains a significant challenge. Methods that rely on explicit structural guidance often enforce rigid spatial constraints that limit semantic flexibility, whereas models tailored for individual control types lack interoperability and adaptability. These design bottlenecks hinder progress toward flexible and efficient semantic video generation. To address this, we propose Video2LoRA, a scalable and generalizable framework for semantic-controlled video generation that conditions on a reference video. Video2LoRA employs a lightweight hypernetwork to predict personalized LoRA weights for each semantic input, which are combined with auxiliary matrices to form adaptive LoRA modules integrated into a frozen diffusion backbone. This design enables the model to generate videos consistent with the reference semantics while preserving key style and content variations, eliminating the need for any per-condition training. Notably, the final model weights less than 150MB, making it highly efficient for storage and deployment. Video2LoRA achieves coherent, semantically aligned generation across diverse conditions and exhibits strong zero-shot generalization to unseen semantics.