Ivanoe De Falco

Giovanna Sannino, Ivanoe De Falco, Nadia Brancati et al.

Recent advances in Artificial Intelligence (AI) and the exploration of noninvasive, objective biomarkers, such as speech signals, have encouraged the development of algorithms to support the early diagnosis of neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS). Voice changes in subjects suffering from ALS typically manifest as progressive dysarthria, which is a prominent neurodegenerative symptom because it affects patients as the disease progresses. Since voice signals are complex data, the development and use of advanced AI techniques are fundamental to extracting distinctive patterns from them. Validating AI algorithms for ALS diagnosis and monitoring using voice signals is challenging, particularly due to the lack of annotated reference datasets. In this work, we present the outcome of a collaboration between a multidisciplinary team of clinicians and Machine Learning experts to create both a clinically annotated validation dataset and the "Speech Analysis for Neurodegenerative Diseases" (SAND) challenge based on it. Specifically, by analyzing voice disorders, the SAND challenge provides an opportunity to develop, test, and evaluate AI models for the automatic early identification and prediction of ALS disease progression.

Antonio Di Marino, Vincenzo Bevilacqua, Emanuel Di Nardo et al.

In the literature, several studies have shown that state-of-the-art image similarity metrics are not perceptual metrics; moreover, they have difficulty evaluating images, especially when texture distortion is also present. In this work, we propose a new perceptual metric composed of two terms. The first term evaluates the dissimilarity between the textures of two images using Earth Mover's Distance. The second term evaluates the chromatic dissimilarity between two images in the Oklab perceptual color space. We evaluated the performance of our metric on a non-traditional dataset, called Berkeley-Adobe Perceptual Patch Similarity, which contains a wide range of complex distortions in shapes and colors. We have shown that our metric outperforms the state of the art, especially when images contain shape distortions, confirming also its greater perceptiveness. Furthermore, although deep black-box metrics could be very accurate, they only provide similarity scores between two images, without explaining their main differences and similarities. Our metric, on the other hand, provides visual explanations to support the calculated score, making the similarity assessment transparent and justified.