LGMar 16Code
Cross-RAG: Zero-Shot Retrieval-Augmented Time Series Forecasting via Cross-AttentionSeunghan Lee, Jaehoon Lee, Jun Seo et al.
Recent advances in time series foundation models (TSFMs) demonstrate strong expressive capacity through large-scale pretraining across diverse time series domains. Zero-shot time series forecasting with TSFMs, however, exhibits limited generalization to unseen datasets, which retrieval-augmented forecasting addresses by leveraging an external knowledge base. Existing approaches rely on a fixed number of retrieved samples that may introduce irrelevant information. To this end, we propose Cross-RAG, a zero-shot retrieval-augmented forecasting framework that selectively attends to query-relevant retrieved samples. Cross-RAG models input-level relevance between the query and retrieved samples via query-retrieval cross-attention, while jointly incorporating information from the query and retrieved samples. Extensive experiments demonstrate that Cross-RAG consistently improves zero-shot forecasting performance across various TSFMs and RAG methods, and additional analyses confirm its effectiveness across diverse retrieval scenarios. Code is available at https://github.com/seunghan96/cross-rag/.
LGMay 6Code
Mitigating Label Shift in Tabular In-Context Learning via Test-Time Posterior AdjustmentSeunghan Lee, Jaehoon Lee, Jun Seo et al.
TabPFN has recently gained attention as a foundation model for tabular datasets, achieving strong performance by leveraging in-context learning on synthetic data. However, we find that TabPFN is vulnerable to label shift, often overfitting to the majority class in the training dataset. To address this limitation, we propose DistPFN, the first test-time posterior adjustment method designed for tabular foundation models. DistPFN rescales predicted class probabilities by downweighting the influence of the training prior (i.e., the class distribution of the context) and emphasizing the contribution of the model's predicted posterior, without architectural modification or additional training. We further introduce DistPFN-T, which incorporates temperature scaling to adaptively control the adjustment strength based on the discrepancy between prior and posterior. We evaluate our methods on over 250 OpenML datasets, demonstrating substantial improvements for various TabPFN-based models in classification tasks under label shift, while maintaining strong performance in standard settings without label shift. Code is available at this repository: https://github.com/seunghan96/DistPFN.
AIMay 8Code
AdaTKG: Adaptive Memory for Temporal Knowledge Graph ReasoningSeunghan Lee, Jun Seo, Jaehoon Lee et al.
Temporal knowledge graphs (TKGs) represent time-stamped relational facts and support a wide range of reasoning tasks over evolving events. However, existing methods produce entity representations that are static at the entity level, in that each representation is a function of learned parameters only and retains no trace of the interactions in which the entity has participated. In this paper, we depart from this static view and propose that each entity be modeled as an adaptive process whose representation is refined every time the entity participates in a fact. To this end, we propose AdaTKG, which maintains a per-entity memory that is updated with every observed interaction, with the memory accumulating online and predictions improving as more interactions arrive. Specifically, we instantiate the memory update as a learnable exponential moving average governed by a single shared scalar instead of using learnable parameters for each entity, enabling AdaTKG to handle entities unseen during training. Extensive experiments confirm consistent gains over TKG baselines, demonstrating the effectiveness of adaptive memory. Code is publicly available at: https://github.com/seunghan96/AdaTKG.
LGMar 23Code
Rethinking Multimodal Fusion for Time Series: Auxiliary Modalities Need Constrained FusionSeunghan Lee, Jun Seo, Jaehoon Lee et al.
Recent advances in multimodal learning have motivated the integration of auxiliary modalities such as text or vision into time series (TS) forecasting. However, most existing methods provide limited gains, often improving performance only in specific datasets or relying on architecture-specific designs that limit generalization. In this paper, we show that multimodal models with naive fusion strategies (e.g., simple addition or concatenation) often underperform unimodal TS models, which we attribute to the uncontrolled integration of auxiliary modalities which may introduce irrelevant information. Motivated by this observation, we explore various constrained fusion methods designed to control such integration and find that they consistently outperform naive fusion methods. Furthermore, we propose Controlled Fusion Adapter (CFA), a simple plug-in method that enables controlled cross-modal interactions without modifying the TS backbone, integrating only relevant textual information aligned with TS dynamics. CFA employs low-rank adapters to filter irrelevant textual information before fusing it into temporal representations. We conduct over 20K experiments across various datasets and TS/text models, demonstrating the effectiveness of the constrained fusion methods including CFA. Code is publicly available at: https://github.com/seunghan96/cfa/.
AIMay 5Code
FinSTaR: Towards Financial Reasoning with Time Series Reasoning ModelsSeunghan Lee, Jun Seo, Jaehoon Lee et al.
Time series (TS) reasoning models (TSRMs) have shown promising capabilities in general domains, yet they consistently fail on financial domain, which exhibit unique characteristics. We propose a general 2x2 capability taxonomy for TSRMs by crossing 1) single-entity vs. multi-entity analysis with 2) assessment of the current state vs. prediction of future behavior. We instantiate this taxonomy in the financial domain -- where the distinction between deterministic assessment and stochastic prediction is particularly critical -- as ten financial reasoning tasks, forming the FinTSR-Bench benchmark based on S&P stocks. To this end, we propose FinSTaR (Financial Time Series Thinking and Reasoning), trained on FinTSR-Bench with distinct chain-of-thought (CoT) strategies tailored to each category. For assessment, which is deterministic (i.e., computable from observable data), we employ Compute-in-CoT, a programmatic CoT that enables models to derive answers directly from raw prices. For prediction, which is inherently stochastic (i.e., subject to unobservable factors), we adopt Scenario-Aware CoT, which generates diverse scenarios before making a judgment, mirroring how financial analysts reason under uncertainty. The proposed method achieves 78.9% average accuracy on FinTSR-Bench, substantially outperforming LLM and TSRM baselines. Furthermore, we show that the four capability categories are complementary and mutually reinforcing through joint training, and that Scenario-Aware CoT consistently improves prediction accuracy over standard CoT. Code is publicly available at: https://github.com/seunghan96/FinSTaR.
CVAug 13, 2024
Bi-directional Contextual Attention for 3D Dense CaptioningMinjung Kim, Hyung Suk Lim, Soonyoung Lee et al.
3D dense captioning is a task involving the localization of objects and the generation of descriptions for each object in a 3D scene. Recent approaches have attempted to incorporate contextual information by modeling relationships with object pairs or aggregating the nearest neighbor features of an object. However, the contextual information constructed in these scenarios is limited in two aspects: first, objects have multiple positional relationships that exist across the entire global scene, not only near the object itself. Second, it faces with contradicting objectives--where localization and attribute descriptions are generated better with tight localization, while descriptions involving global positional relations are generated better with contextualized features of the global scene. To overcome this challenge, we introduce BiCA, a transformer encoder-decoder pipeline that engages in 3D dense captioning for each object with Bi-directional Contextual Attention. Leveraging parallelly decoded instance queries for objects and context queries for non-object contexts, BiCA generates object-aware contexts, where the contexts relevant to each object is summarized, and context-aware objects, where the objects relevant to the summarized object-aware contexts are aggregated. This extension relieves previous methods from the contradicting objectives, enhancing both localization performance and enabling the aggregation of contextual features throughout the global scene; thus improving caption generation performance simultaneously. Extensive experiments on two of the most widely-used 3D dense captioning datasets demonstrate that our proposed method achieves a significant improvement over prior methods.
CVAug 14, 2024
See It All: Contextualized Late Aggregation for 3D Dense CaptioningMinjung Kim, Hyung Suk Lim, Seung Hwan Kim et al.
3D dense captioning is a task to localize objects in a 3D scene and generate descriptive sentences for each object. Recent approaches in 3D dense captioning have adopted transformer encoder-decoder frameworks from object detection to build an end-to-end pipeline without hand-crafted components. However, these approaches struggle with contradicting objectives where a single query attention has to simultaneously view both the tightly localized object regions and contextual environment. To overcome this challenge, we introduce SIA (See-It-All), a transformer pipeline that engages in 3D dense captioning with a novel paradigm called late aggregation. SIA simultaneously decodes two sets of queries-context query and instance query. The instance query focuses on localization and object attribute descriptions, while the context query versatilely captures the region-of-interest of relationships between multiple objects or with the global scene, then aggregated afterwards (i.e., late aggregation) via simple distance-based measures. To further enhance the quality of contextualized caption generation, we design a novel aggregator to generate a fully informed caption based on the surrounding context, the global environment, and object instances. Extensive experiments on two of the most widely-used 3D dense captioning datasets demonstrate that our proposed method achieves a significant improvement over prior methods.
LGAug 1, 2024
EXAONEPath 1.0 Patch-level Foundation Model for PathologyJuseung Yun, Yi Hu, Jinhyung Kim et al.
Recent advancements in digital pathology have led to the development of numerous foundational models that utilize self-supervised learning on patches extracted from gigapixel whole slide images (WSIs). While this approach leverages vast amounts of unlabeled data, we have discovered a significant issue: features extracted from these self-supervised models tend to cluster by individual WSIs, a phenomenon we term WSI-specific feature collapse. This problem can potentially limit the model's generalization ability and performance on various downstream tasks. To address this issue, we introduce EXAONEPath, a novel foundational model trained on patches that have undergone stain normalization. Stain normalization helps reduce color variability arising from different laboratories and scanners, enabling the model to learn more consistent features. EXAONEPath is trained using 285,153,903 patches extracted from a total of 34,795 WSIs. Our experiments demonstrate that EXAONEPath significantly mitigates the feature collapse problem, indicating that the model has learned more generalized features rather than overfitting to individual WSI characteristics. We compared EXAONEPath with state-of-the-art models across six downstream task datasets, and our results show that EXAONEPath achieves superior performance relative to the number of WSIs used and the model's parameter count. This suggests that the application of stain normalization has substantially improved the model's efficiency and generalization capabilities.
LGApr 7
Channel-wise Retrieval for Multivariate Time Series ForecastingJunhyeok Kang, Jun Seo, Soyeon Park et al.
Multivariate time series forecasting often struggles to capture long-range dependencies due to fixed lookback windows. Retrieval-augmented forecasting addresses this by retrieving historical segments from memory, but existing approaches rely on a channel-agnostic strategy that applies the same references to all variables. This neglects inter-variable heterogeneity, where different channels exhibit distinct periodicities and spectral profiles. We propose CRAFT (Channel-wise retrieval-augmented forecasting), a novel framework that performs retrieval independently for each channel. To ensure efficiency, CRAFT adopts a two-stage pipeline: a sparse relation graph constructed in the time domain prunes irrelevant candidates, and spectral similarity in the frequency domain ranks references, emphasizing dominant periodic components while suppressing noise. Experiments on seven public benchmarks demonstrate that CRAFT outperforms state-of-the-art forecasting baselines, achieving superior accuracy with practical inference efficiency.
CVDec 21, 2023Code
Universal Noise Annotation: Unveiling the Impact of Noisy annotation on Object DetectionKwangrok Ryoo, Yeonsik Jo, Seungjun Lee et al.
For object detection task with noisy labels, it is important to consider not only categorization noise, as in image classification, but also localization noise, missing annotations, and bogus bounding boxes. However, previous studies have only addressed certain types of noise (e.g., localization or categorization). In this paper, we propose Universal-Noise Annotation (UNA), a more practical setting that encompasses all types of noise that can occur in object detection, and analyze how UNA affects the performance of the detector. We analyzed the development direction of previous works of detection algorithms and examined the factors that impact the robustness of detection model learning method. We open-source the code for injecting UNA into the dataset and all the training log and weight are also shared.
CVApr 21, 2025Code
ReSpec: Relevance and Specificity Grounded Online Filtering for Learning on Video-Text Data StreamsChris Dongjoo Kim, Jihwan Moon, Sangwoo Moon et al. · allen-ai
The rapid growth of video-text data presents challenges in storage and computation during training. Online learning, which processes streaming data in real-time, offers a promising solution to these issues while also allowing swift adaptations in scenarios demanding real-time responsiveness. One strategy to enhance the efficiency and effectiveness of learning involves identifying and prioritizing data that enhances performance on target downstream tasks. We propose Relevance and Specificity-based online filtering framework (ReSpec) that selects data based on four criteria: (i) modality alignment for clean data, (ii) task relevance for target focused data, (iii) specificity for informative and detailed data, and (iv) efficiency for low-latency processing. Relevance is determined by the probabilistic alignment of incoming data with downstream tasks, while specificity employs the distance to a root embedding representing the least specific data as an efficient proxy for informativeness. By establishing reference points from target task data, ReSpec filters incoming data in real-time, eliminating the need for extensive storage and compute. Evaluating on large-scale datasets WebVid2M and VideoCC3M, ReSpec attains state-of-the-art performance on five zeroshot video retrieval tasks, using as little as 5% of the data while incurring minimal compute. The source code is available at https://github.com/cdjkim/ReSpec.
CVJun 13, 2024Code
Exploring the Spectrum of Visio-Linguistic Compositionality and RecognitionYoungtaek Oh, Pyunghwan Ahn, Jinhyung Kim et al.
Vision and language models (VLMs) such as CLIP have showcased remarkable zero-shot recognition abilities yet face challenges in visio-linguistic compositionality, particularly in linguistic comprehension and fine-grained image-text alignment. This paper explores the intricate relationship between compositionality and recognition -- two pivotal aspects of VLM capability. We conduct a comprehensive evaluation of existing VLMs, covering both pre-training approaches aimed at recognition and the fine-tuning methods designed to improve compositionality. Our evaluation employs 12 benchmarks for compositionality, along with 21 zero-shot classification and two retrieval benchmarks for recognition. In our analysis from 274 CLIP model checkpoints, we reveal patterns and trade-offs that emerge between compositional understanding and recognition accuracy. Ultimately, this necessitates strategic efforts towards developing models that improve both capabilities, as well as the meticulous formulation of benchmarks for compositionality. We open our evaluation framework at https://github.com/ytaek-oh/vl_compo.
AIMar 3
FinTexTS: Financial Text-Paired Time-Series Dataset via Semantic-Based and Multi-Level PairingJaehoon Lee, Suhwan Park, Tae Yoon Lim et al.
The financial domain involves a variety of important time-series problems. Recently, time-series analysis methods that jointly leverage textual and numerical information have gained increasing attention. Accordingly, numerous efforts have been made to construct text-paired time-series datasets in the financial domain. However, financial markets are characterized by complex interdependencies, in which a company's stock price is influenced not only by company-specific events but also by events in other companies and broader macroeconomic factors. Existing approaches that pair text with financial time-series data based on simple keyword matching often fail to capture such complex relationships. To address this limitation, we propose a semantic-based and multi-level pairing framework. Specifically, we extract company-specific context for the target company from SEC filings and apply an embedding-based matching mechanism to retrieve semantically relevant news articles based on this context. Furthermore, we classify news articles into four levels (macro-level, sector-level, related company-level, and target-company level) using large language models (LLMs), enabling multi-level pairing of news articles with the target company. Applying this framework to publicly-available news datasets, we construct \textbf{FinTexTS}, a new large-scale text-paired stock price dataset. Experimental results on \textbf{FinTexTS} demonstrate the effectiveness of our semantic-based and multi-level pairing strategy in stock price forecasting. In addition to publicly-available news underlying \textbf{FinTexTS}, we show that applying our method to proprietary yet carefully curated news sources leads to higher-quality paired data and improved stock price forecasting performance.
LGFeb 9
CADO: From Imitation to Cost Minimization for Heatmap-based Solvers in Combinatorial OptimizationHyungseok Song, Deunsol Yoon, Kanghoon Lee et al.
Heatmap-based solvers have emerged as a promising paradigm for Combinatorial Optimization (CO). However, we argue that the dominant Supervised Learning (SL) training paradigm suffers from a fundamental objective mismatch: minimizing imitation loss (e.g., cross-entropy) does not guarantee solution cost minimization. We dissect this mismatch into two deficiencies: Decoder-Blindness (being oblivious to the non-differentiable decoding process) and Cost-Blindness (prioritizing structural imitation over solution quality). We empirically demonstrate that these intrinsic flaws impose a hard performance ceiling. To overcome this limitation, we propose CADO (Cost-Aware Diffusion models for Optimization), a streamlined Reinforcement Learning fine-tuning framework that formulates the diffusion denoising process as an MDP to directly optimize the post-decoded solution cost. We introduce Label-Centered Reward, which repurposes ground-truth labels as unbiased baselines rather than imitation targets, and Hybrid Fine-Tuning for parameter-efficient adaptation. CADO achieves state-of-the-art performance across diverse benchmarks, validating that objective alignment is essential for unlocking the full potential of heatmap-based solvers.
LGDec 16, 2025
EXAONE Path 2.5: Pathology Foundation Model with Multi-Omics AlignmentJuseung Yun, Sunwoo Yu, Sumin Ha et al.
Cancer progression arises from interactions across multiple biological layers, especially beyond morphological and across molecular layers that remain invisible to image-only models. To capture this broader biological landscape, we present EXAONE Path 2.5, a pathology foundation model that jointly models histologic, genomic, epigenetic and transcriptomic modalities, producing an integrated patient representation that reflects tumor biology more comprehensively. Our approach incorporates three key components: (1) multimodal SigLIP loss enabling all-pairwise contrastive learning across heterogeneous modalities, (2) a fragment-aware rotary positional encoding (F-RoPE) module that preserves spatial structure and tissue-fragment topology in WSI, and (3) domain-specialized internal foundation models for both WSI and RNA-seq to provide biologically grounded embeddings for robust multimodal alignment. We evaluate EXAONE Path 2.5 against six leading pathology foundation models across two complementary benchmarks: an internal real-world clinical dataset and the Patho-Bench benchmark covering 80 tasks. Our framework demonstrates high data and parameter efficiency, achieving on-par performance with state-of-the-art foundation models on Patho-Bench while exhibiting the highest adaptability in the internal clinical setting. These results highlight the value of biologically informed multimodal design and underscore the potential of integrated genotype-to-phenotype modeling for next-generation precision oncology.
CVMar 20, 2025
MASH-VLM: Mitigating Action-Scene Hallucination in Video-LLMs through Disentangled Spatial-Temporal RepresentationsKyungho Bae, Jinhyung Kim, Sihaeng Lee et al.
In this work, we tackle action-scene hallucination in Video Large Language Models (Video-LLMs), where models incorrectly predict actions based on the scene context or scenes based on observed actions. We observe that existing Video-LLMs often suffer from action-scene hallucination due to two main factors. First, existing Video-LLMs intermingle spatial and temporal features by applying an attention operation across all tokens. Second, they use the standard Rotary Position Embedding (RoPE), which causes the text tokens to overemphasize certain types of tokens depending on their sequential orders. To address these issues, we introduce MASH-VLM, Mitigating Action-Scene Hallucination in Video-LLMs through disentangled spatial-temporal representations. Our approach includes two key innovations: (1) DST-attention, a novel attention mechanism that disentangles the spatial and temporal tokens within the LLM by using masked attention to restrict direct interactions between the spatial and temporal tokens; (2) Harmonic-RoPE, which extends the dimensionality of the positional IDs, allowing the spatial and temporal tokens to maintain balanced positions relative to the text tokens. To evaluate the action-scene hallucination in Video-LLMs, we introduce the UNSCENE benchmark with 1,320 videos and 4,078 QA pairs. Extensive experiments demonstrate that MASH-VLM achieves state-of-the-art results on the UNSCENE benchmark, as well as on existing video understanding benchmarks.
CVJul 9, 2025
EXAONE Path 2.0: Pathology Foundation Model with End-to-End SupervisionMyeongjang Pyeon, Janghyeon Lee, Minsoo Lee et al.
In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via multiple instance learning (MIL) or slide encoders for downstream tasks. However, patch-level SSL may overlook complex domain-specific features that are essential for biomarker prediction, such as mutation status and molecular characteristics, as SSL methods rely only on basic augmentations selected for natural image domains on small patch-level area. Moreover, SSL methods remain less data efficient than fully supervised approaches, requiring extensive computational resources and datasets to achieve competitive performance. To address these limitations, we present EXAONE Path 2.0, a pathology foundation model that learns patch-level representations under direct slide-level supervision. Using only 37k WSIs for training, EXAONE Path 2.0 achieves state-of-the-art average performance across 10 biomarker prediction tasks, demonstrating remarkable data efficiency.
LGDec 11, 2025
Adaptive Information Routing for Multimodal Time Series ForecastingJun Seo, Hyeokjun Choe, Seohui Bae et al.
Time series forecasting is a critical task for artificial intelligence with numerous real-world applications. Traditional approaches primarily rely on historical time series data to predict the future values. However, in practical scenarios, this is often insufficient for accurate predictions due to the limited information available. To address this challenge, multimodal time series forecasting methods which incorporate additional data modalities, mainly text data, alongside time series data have been explored. In this work, we introduce the Adaptive Information Routing (AIR) framework, a novel approach for multimodal time series forecasting. Unlike existing methods that treat text data on par with time series data as interchangeable auxiliary features for forecasting, AIR leverages text information to dynamically guide the time series model by controlling how and to what extent multivariate time series information should be combined. We also present a text-refinement pipeline that employs a large language model to convert raw text data into a form suitable for multimodal forecasting, and we introduce a benchmark that facilitates multimodal forecasting experiments based on this pipeline. Experiment results with the real world market data such as crude oil price and exchange rates demonstrate that AIR effectively modulates the behavior of the time series model using textual inputs, significantly enhancing forecasting accuracy in various time series forecasting tasks.
AIOct 2, 2025
ReTabAD: A Benchmark for Restoring Semantic Context in Tabular Anomaly DetectionSanghyu Yoon, Dongmin Kim, Suhee Yoon et al.
In tabular anomaly detection (AD), textual semantics often carry critical signals, as the definition of an anomaly is closely tied to domain-specific context. However, existing benchmarks provide only raw data points without semantic context, overlooking rich textual metadata such as feature descriptions and domain knowledge that experts rely on in practice. This limitation restricts research flexibility and prevents models from fully leveraging domain knowledge for detection. ReTabAD addresses this gap by restoring textual semantics to enable context-aware tabular AD research. We provide (1) 20 carefully curated tabular datasets enriched with structured textual metadata, together with implementations of state-of-the-art AD algorithms including classical, deep learning, and LLM-based approaches, and (2) a zero-shot LLM framework that leverages semantic context without task-specific training, establishing a strong baseline for future research. Furthermore, this work provides insights into the role and utility of textual metadata in AD through experiments and analysis. Results show that semantic context improves detection performance and enhances interpretability by supporting domain-aware reasoning. These findings establish ReTabAD as a benchmark for systematic exploration of context-aware AD.
LGSep 25, 2025
Robust Multi-Omics Integration from Incomplete Modalities Significantly Improves Prediction of Alzheimer's DiseaseSungjoon Park, Kyungwook Lee, Soorin Yim et al.
Multi-omics data capture complex biomolecular interactions and provide insights into metabolism and disease. However, missing modalities hinder integrative analysis across heterogeneous omics. To address this, we present MOIRA (Multi-Omics Integration with Robustness to Absent modalities), an early integration method enabling robust learning from incomplete omics data via representation alignment and adaptive aggregation. MOIRA leverages all samples, including those with missing modalities, by projecting each omics dataset onto a shared embedding space where a learnable weighting mechanism fuses them. Evaluated on the Religious Order Study and Memory and Aging Project (ROSMAP) dataset for Alzheimer's Disease (AD), MOIRA outperformed existing approaches, and further ablation studies confirmed modality-wise contributions. Feature importance analysis revealed AD-related biomarkers consistent with prior literature, highlighting the biological relevance of our approach.
LGApr 30, 2025
MolMole: Molecule Mining from Scientific LiteratureLG AI Research, Sehyun Chun, Jiye Kim et al.
The extraction of molecular structures and reaction data from scientific documents is challenging due to their varied, unstructured chemical formats and complex document layouts. To address this, we introduce MolMole, a vision-based deep learning framework that unifies molecule detection, reaction diagram parsing, and optical chemical structure recognition (OCSR) into a single pipeline for automating the extraction of chemical data directly from page-level documents. Recognizing the lack of a standard page-level benchmark and evaluation metric, we also present a testset of 550 pages annotated with molecule bounding boxes, reaction labels, and MOLfiles, along with a novel evaluation metric. Experimental results demonstrate that MolMole outperforms existing toolkits on both our benchmark and public datasets. The benchmark testset will be publicly available, and the MolMole toolkit will be accessible soon through an interactive demo on the LG AI Research website. For commercial inquiries, please contact us at \href{mailto:contact_ddu@lgresearch.ai}{contact\_ddu@lgresearch.ai}.
CLApr 17, 2025
ChatEXAONEPath: An Expert-level Multimodal Large Language Model for Histopathology Using Whole Slide ImagesSangwook Kim, Soonyoung Lee, Jongseong Jang
Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios. Studies have also witnessed the importance of integrating various modalities with the existing LLMs for a better understanding of complex clinical contexts, which are innately multi-faceted by nature. Although studies have demonstrated the ability of multimodal LLMs in histopathology to answer questions from given images, they lack in understanding of thorough clinical context due to the patch-level data with limited information from public datasets. Thus, developing WSI-level MLLMs is significant in terms of the scalability and applicability of MLLMs in histopathology. In this study, we introduce an expert-level MLLM for histopathology using WSIs, dubbed as ChatEXAONEPath. We present a retrieval-based data generation pipeline using 10,094 pairs of WSIs and histopathology reports from The Cancer Genome Atlas (TCGA). We also showcase an AI-based evaluation protocol for a comprehensive understanding of the medical context from given multimodal information and evaluate generated answers compared to the original histopathology reports. We demonstrate the ability of diagnosing the given histopathology images using ChatEXAONEPath with the acceptance rate of 62.9% from 1,134 pairs of WSIs and reports. Our proposed model can understand pan-cancer WSIs and clinical context from various cancer types. We argue that our proposed model has the potential to assist clinicians by comprehensively understanding complex morphology of WSIs for cancer diagnosis through the integration of multiple modalities.
CVNov 22, 2021
L-Verse: Bidirectional Generation Between Image and TextTaehoon Kim, Gwangmo Song, Sihaeng Lee et al.
Far beyond learning long-range interactions of natural language, transformers are becoming the de-facto standard for many vision tasks with their power and scalability. Especially with cross-modal tasks between image and text, vector quantized variational autoencoders (VQ-VAEs) are widely used to make a raw RGB image into a sequence of feature vectors. To better leverage the correlation between image and text, we propose L-Verse, a novel architecture consisting of feature-augmented variational autoencoder (AugVAE) and bidirectional auto-regressive transformer (BiART) for image-to-text and text-to-image generation. Our AugVAE shows the state-of-the-art reconstruction performance on ImageNet1K validation set, along with the robustness to unseen images in the wild. Unlike other models, BiART can distinguish between image (or text) as a conditional reference and a generation target. L-Verse can be directly used for image-to-text or text-to-image generation without any finetuning or extra object detection framework. In quantitative and qualitative experiments, L-Verse shows impressive results against previous methods in both image-to-text and text-to-image generation on MS-COCO Captions. We furthermore assess the scalability of L-Verse architecture on Conceptual Captions and present the initial result of bidirectional vision-language representation learning on general domain.