Chaozheng Huang

Hanzheng Li, Xi Fang, Yixuan Li et al.

The integration of Multimodal Large Language Models (MLLMs) into chemistry promises to revolutionize scientific discovery, yet their ability to comprehend the dense, graphical language of reactions within authentic literature remains underexplored. Here, we introduce RxnBench, a multi-tiered benchmark designed to rigorously evaluate MLLMs on chemical reaction understanding from scientific PDFs. RxnBench comprises two tasks: Single-Figure QA (SF-QA), which tests fine-grained visual perception and mechanistic reasoning using 1,525 questions derived from 305 curated reaction schemes, and Full-Document QA (FD-QA), which challenges models to synthesize information from 108 articles, requiring cross-modal integration of text, schemes, and tables. Our evaluation of MLLMs reveals a critical capability gap: while models excel at extracting explicit text, they struggle with deep chemical logic and precise structural recognition. Notably, models with inference-time reasoning significantly outperform standard architectures, yet none achieve 50\% accuracy on FD-QA. These findings underscore the urgent need for domain-specific visual encoders and stronger reasoning engines to advance autonomous AI chemists.

Jindi Guo, Xi Fang, Chaozheng Huang

We introduce MMTR-Bench, a benchmark designed to evaluate the intrinsic ability of Multimodal Large Language Models (MLLMs) to reconstruct masked text directly from visual context. Unlike conventional question-answering tasks, MMTR-Bench eliminates explicit prompts, requiring models to recover masked text from single- or multi-page inputs across real-world domains such as documents and webpages. This design isolates the reconstruction task from instruction-following abilities, enabling a direct assessment of a model's layout understanding, visual grounding, and knowledge integration. MMTR-Bench comprises 2,771 test samples spanning multiple languages and varying target lengths. To account for this diversity, we propose a level-aware evaluation protocol. Experiments on representative MLLMs show that the benchmark poses a significant challenge, especially for sentence- and paragraph-level reconstruction. The homepage is available at https://mmtr-bench-dataset.github.io/MMTR-Bench/.

Xi Fang, Haoyi Tao, Shuwen Yang et al.

This technical report introduces Uni-Parser, an industrial-grade document parsing engine tailored for scientific literature and patents, delivering high throughput, robust accuracy, and cost efficiency. Unlike pipeline-based document parsing methods, Uni-Parser employs a modular, loosely coupled multi-expert architecture that preserves fine-grained cross-modal alignments across text, equations, tables, figures, and chemical structures, while remaining easily extensible to emerging modalities. The system incorporates adaptive GPU load balancing, distributed inference, dynamic module orchestration, and configurable modes that support either holistic or modality-specific parsing. Optimized for large-scale cloud deployment, Uni-Parser achieves a processing rate of up to 20 PDF pages per second on 8 x NVIDIA RTX 4090D GPUs, enabling cost-efficient inference across billions of pages. This level of scalability facilitates a broad spectrum of downstream applications, ranging from literature retrieval and summarization to the extraction of chemical structures, reaction schemes, and bioactivity data, as well as the curation of large-scale corpora for training next-generation large language models and AI4Science models.