Xueyuan Li

Xueyuan Li, Ruining Deng, Yucheng Tang et al.

Precise identification of multiple cell classes in high-resolution Giga-pixel whole slide imaging (WSI) is critical for various clinical scenarios. Building an AI model for this purpose typically requires pixel-level annotations, which are often unscalable and must be done by skilled domain experts (e.g., pathologists). However, these annotations can be prone to errors, especially when distinguishing between intricate cell types (e.g., podocytes and mesangial cells) using only visual inspection. Interestingly, a recent study showed that lay annotators, when using extra immunofluorescence (IF) images for reference (referred to as molecular-empowered learning), can sometimes outperform domain experts in labeling. Despite this, the resource-intensive task of manual delineation remains a necessity during the annotation process. In this paper, we explore the potential of bypassing pixel-level delineation by employing the recent segment anything model (SAM) on weak box annotation in a zero-shot learning approach. Specifically, we harness SAM's ability to produce pixel-level annotations from box annotations and utilize these SAM-generated labels to train a segmentation model. Our findings show that the proposed SAM-assisted molecular-empowered learning (SAM-L) can diminish the labeling efforts for lay annotators by only requiring weak box annotations. This is achieved without compromising annotation accuracy or the performance of the deep learning-based segmentation. This research represents a significant advancement in democratizing the annotation process for training pathological image segmentation, relying solely on non-expert annotators.

Xin Gao, Xueyuan Li, Hao Liu et al.

Platooning technology is renowned for its precise vehicle control, traffic flow optimization, and energy efficiency enhancement. However, in large-scale mixed platoons, vehicle heterogeneity and unpredictable traffic conditions lead to virtual bottlenecks. These bottlenecks result in reduced traffic throughput and increased energy consumption within the platoon. To address these challenges, we introduce a decision-making strategy based on nested graph reinforcement learning. This strategy improves collaborative decision-making, ensuring energy efficiency and alleviating congestion. We propose a theory of nested traffic graph representation that maps dynamic interactions between vehicles and platoons in non-Euclidean spaces. By incorporating spatio-temporal weighted graph into a multi-head attention mechanism, we further enhance the model's capacity to process both local and global data. Additionally, we have developed a nested graph reinforcement learning framework to enhance the self-iterative learning capabilities of platooning. Using the I-24 dataset, we designed and conducted comparative algorithm experiments, generalizability testing, and permeability ablation experiments, thereby validating the proposed strategy's effectiveness. Compared to the baseline, our strategy increases throughput by 10% and decreases energy use by 9%. Specifically, increasing the penetration rate of CAVs significantly enhances traffic throughput, though it also increases energy consumption.

Qi Liu, Zirui Li, Xueyuan Li et al.

An efficient and reliable multi-agent decision-making system is highly demanded for the safe and efficient operation of connected autonomous vehicles in intelligent transportation systems. Current researches mainly focus on the Deep Reinforcement Learning (DRL) methods. However, utilizing DRL methods in interactive traffic scenarios is hard to represent the mutual effects between different vehicles and model the dynamic traffic environments due to the lack of interactive information in the representation of the environments, which results in low accuracy of cooperative decisions generation. To tackle these difficulties, this research proposes a framework to enable different Graph Reinforcement Learning (GRL) methods for decision-making, and compares their performance in interactive driving scenarios. GRL methods combinate the Graph Neural Network (GNN) and DRL to achieve the better decisions generation in interactive scenarios of autonomous vehicles, where the features of interactive scenarios are extracted by the GNN, and cooperative behaviors are generated by DRL framework. Several GRL approaches are summarized and implemented in the proposed framework. To evaluate the performance of the proposed GRL methods, an interactive driving scenarios on highway with two ramps is constructed, and simulated experiment in the SUMO platform is carried out to evaluate the performance of different GRL approaches. Finally, results are analyzed in multiple perspectives and dimensions to compare the characteristic of different GRL approaches in intelligent transportation scenarios. Results show that the implementation of GNN can well represents the interaction between vehicles, and the combination of GNN and DRL is able to improve the performance of the generation of lane-change behaviors. The source code of our work can be found at https://github.com/Jacklinkk/TorchGRL.

Xueyuan Li, Can Cui, Ruining Deng et al.

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods: prompt-based zero-shot segmentation and the use of cell-specific SAM models for direct segmentation. These approaches enable effective segmentation across a range of nuclei and cells. However, general vision foundation models often face challenges with fine-grained semantic segmentation, such as identifying specific nuclei subtypes or particular cells. Approach: In this paper, we propose the molecular-empowered All-in-SAM Model to advance computational pathology by leveraging the capabilities of vision foundation models. This model incorporates a full-stack approach, focusing on: (1) annotation-engaging lay annotators through molecular-empowered learning to reduce the need for detailed pixel-level annotations, (2) learning-adapting the SAM model to emphasize specific semantics, which utilizes its strong generalizability with SAM adapter, and (3) refinement-enhancing segmentation accuracy by integrating Molecular-Oriented Corrective Learning (MOCL). Results: Experimental results from both in-house and public datasets show that the All-in-SAM model significantly improves cell classification performance, even when faced with varying annotation quality. Conclusions: Our approach not only reduces the workload for annotators but also extends the accessibility of precise biomedical image analysis to resource-limited settings, thereby advancing medical diagnostics and automating pathology image analysis.

Qi Liu, Xueyuan Li, Zirui Li et al.

Navigating heterogeneous traffic environments with diverse driving styles poses a significant challenge for autonomous vehicles (AVs) due to their inherent complexity and dynamic interactions. This paper addresses this challenge by proposing a heterogeneous graph reinforcement learning (GRL) framework enhanced with an expert system to improve AV decision-making performance. Initially, a heterogeneous graph representation is introduced to capture the intricate interactions among vehicles. Then, a heterogeneous graph neural network with an expert model (HGNN-EM) is proposed to effectively encode diverse vehicle features and produce driving instructions informed by domain-specific knowledge. Moreover, the double deep Q-learning (DDQN) algorithm is utilized to train the decision-making model. A case study on a typical four-way intersection, involving various driving styles of human vehicles (HVs), demonstrates that the proposed method has superior performance over several baselines regarding safety, efficiency, stability, and convergence rate, all while maintaining favorable real-time performance.

Yinsong Chen, Kaifeng Wang, Xiaoqiang Meng et al.

Current research on decision-making in safety-critical scenarios often relies on inefficient data-driven scenario generation or specific modeling approaches, which fail to capture corner cases in real-world contexts. To address this issue, we propose a Red-Team Multi-Agent Reinforcement Learning framework, where background vehicles with interference capabilities are treated as red-team agents. Through active interference and exploration, red-team vehicles can uncover corner cases outside the data distribution. The framework uses a Constraint Graph Representation Markov Decision Process, ensuring that red-team vehicles comply with safety rules while continuously disrupting the autonomous vehicles (AVs). A policy threat zone model is constructed to quantify the threat posed by red-team vehicles to AVs, inducing more extreme actions to increase the danger level of the scenario. Experimental results show that the proposed framework significantly impacts AVs decision-making safety and generates various corner cases. This method also offers a novel direction for research in safety-critical scenarios.

Qi Liu, Xueyuan Li, Shihua Yuan et al.

Autonomous vehicles have a great potential in the application of both civil and military fields, and have become the focus of research with the rapid development of science and economy. This article proposes a brief review on learning-based decision-making technology for autonomous vehicles since it is significant for safer and efficient performance of autonomous vehicles. Firstly, the basic outline of decision-making technology is provided. Secondly, related works about learning-based decision-making methods for autonomous vehicles are mainly reviewed with the comparison to classical decision-making methods. In addition, applications of decision-making methods in existing autonomous vehicles are summarized. Finally, promising research topics in the future study of decision-making technology for autonomous vehicles are prospected.

Huanjie Wang, Wenshuo Wang, Shihua Yuan et al.

Humans make daily routine decisions based on their internal states in intricate interaction scenarios. This paper presents a probabilistically reconstructive learning approach to identify the internal states of multi-vehicle sequential interactions when merging at highway on-ramps. We treated the merging task's sequential decision as a dynamic, stochastic process and then integrated the internal states into an HMM-GMR model, a probabilistic combination of an extended Gaussian mixture regression (GMR) and hidden Markov models (HMM). We also developed a variant expectation-maximum (EM) algorithm to estimate the model parameters and verified it based on a real-world data set. Experiment results reveal that three interpretable internal states can semantically describe the interactive merge procedure at highway on-ramps. This finding provides a basis to develop an efficient model-based decision-making algorithm for autonomous vehicles (AVs) in a partially observable environment.

Huanjie Wang, Wenshuo Wang, Shihua Yuan et al.

Merging at highway on-ramps while interacting with other human-driven vehicles is challenging for autonomous vehicles (AVs). An efficient route to this challenge requires exploring and exploiting knowledge of the interaction process from demonstrations by humans. However, it is unclear what information (or environmental states) is utilized by the human driver to guide their behavior throughout the whole merging process. This paper provides quantitative analysis and evaluation of the merging behavior at highway on-ramps with congested traffic in a volume of time and space. Two types of social interaction scenarios are considered based on the social preferences of surrounding vehicles: courteous and rude. The significant levels of environmental states for characterizing the interactive merging process are empirically analyzed based on the real-world INTERACTION dataset. Experimental results reveal two fundamental mechanisms in the merging process: 1) Human drivers select different states to make sequential decisions at different moments of task execution, and 2) the social preference of surrounding vehicles can impact variable selection for making decisions. It implies that efficient decision-making design should filter out irrelevant information while considering social preference to achieve comparable human-level performance. These essential findings shed light on developing new decision-making approaches for AVs.

Tianyu Shi, Zhichao Wang, Chong hao Zou et al.

In this paper,we design a formation control systrm for multi-unmanned ground vehicles(UGV) from the prospective of path planning and path tracking.The master-slave control is adopted by electing out a main vehicle to address the problem of possible accumulation,tranmission and amplification of errors.In the process of formation transformation,we first generate an expected path by combing the methods of dynamic window and potential energy field.Then a path tracking algorithm based on Hermite curve is adopted to make the formation transformation process more stable and accurate.Finally,the evaluation system of the formation control system is constructed,which combines the expected position,the actual position,the expected speed, the actual speed and the actual acceleration,giving an evalutaion on the performance of the formation transformation,response of the formation driving process and the performance of the formation stability.