Xurui Li

Yongnan Jin, Xurui Li, Feng Cao et al.

The integration of large language models (LLMs) into medical practice holds transformative potential, yet their real-world clinical utility remains limited by critical alignment challenges: (1) a disconnect between static evaluation benchmarks and dynamic clinical cognitive needs, (2) difficulties in adapting to evolving, multi-source medical standards, and (3) the inability of conventional reward models to capture nuanced, multi-dimensional medical quality criteria. To address these gaps, we propose MR-RML (Multidimensional Rubric-oriented Reward Model Learning) via GPRC (Geometric Projection Reference Constraints), a novel alignment framework that integrates medical standards into a structured "Dimensions-Scenarios-Disciplines" matrix to guide data generation and model optimization. MR-RML introduces three core innovations: (1) a "Dimensions-Scenarios-Disciplines" medical standard system that embeds domain standards into the full training pipeline; (2) an independent multi-dimensional reward model that decomposes evaluation criteria, shifting from real-time rubric-based scoring to internalized reward modeling for improved consistency and cost-efficiency; (3) geometric projection reference constraints that transform medical cognitive logic into mathematical regularization, aligning scoring gradients with clinical reasoning and enabling synthetic data-driven training. Through extensive evaluations on the authoritative medical benchmark Healthbench, our method yields substantial performance gains over the base LLM Qwen-32B (45% on the full subset and 85% on Hard subset, respectively). It achieves a SOTA among open-source LLMs with scores of 62.7 (full subset) and 44.7 (hard subset), while also outperforming the majority of closed-source models.

Tianqianjin Lin, Kaisong Song, Zhuoren Jiang et al.

Heterogeneous graph neural networks have become popular in various domains. However, their generalizability and interpretability are limited due to the discrepancy between their inherent inference flows and human reasoning logic or underlying causal relationships for the learning problem. This study introduces a novel solution, HG-SCM (Heterogeneous Graph as Structural Causal Model). It can mimic the human perception and decision process through two key steps: constructing intelligible variables based on semantics derived from the graph schema and automatically learning task-level causal relationships among these variables by incorporating advanced causal discovery techniques. We compared HG-SCM to seven state-of-the-art baseline models on three real-world datasets, under three distinct and ubiquitous out-of-distribution settings. HG-SCM achieved the highest average performance rank with minimal standard deviation, substantiating its effectiveness and superiority in terms of both predictive power and generalizability. Additionally, the visualization and analysis of the auto-learned causal diagrams for the three tasks aligned well with domain knowledge and human cognition, demonstrating prominent interpretability. HG-SCM's human-like nature and its enhanced generalizability and interpretability make it a promising solution for special scenarios where transparency and trustworthiness are paramount.