Ufaq Khan

Sofiat Abioye, Ufaq Khan, Shazad Ashraf et al.

Clinical pathways are disseminated as visual flowcharts where spatial topology, arrow direction, colour coding, and font weight encode critical triage logic that remains inaccessible to computational systems. We present PathWISE, a five-phase pipeline combining four LLM-based agents with a deterministic depth-first search auditor and a Java compiler critic, transforming these non-computable artefacts into validated, executable HL7 Clinical Quality Language (CQL) libraries deployable as FHIR CDS Hooks services. Purpose-built agents extract flowchart structure into a typed directed graph, perform deterministic path enumeration, conduct a structured semantic audit of every node's computability, generate terminology-constrained CQL definitions verified by the official Java CQL-to-ELM compiler, and produce routing logic covering 100% of enumerated patient journeys. Demonstrated across five UK NHS cancer pathways (colorectal, lung, skin, upper GI, and breast), PathWISE audits up to 183 nodes (182 under the Hybrid configuration), identifies 544 structured governance findings across four issue categories, achieves 100% syntactic compilation success, with UNCOMPUTABLE nodes receiving false placeholders that preserve compilability while surfacing governance gaps for clinical review, and produces zero hallucinated terminology codes for dictionary-covered concepts. Critically, PathWISE confines non-deterministic LLM inference to knowledge extraction while deterministic graph mathematics and a standard compiler underpin every verification step.

Bonan Ding, Umair Nawaz, Ufaq Khan et al.

Pre-trained video large language models excel at visual reasoning. However, they struggle when videos arrive with auxiliary streams, such as audio, depth map, or dense temporal evidence. In such a scenario, uniform fusion induces modality interference, allowing irrelevant channels to distract the model. To address this issue, we present a unified multimodal video understanding framework, named UniMVU, that performs instruction-aware fusion across video, audio, depth map, or any other modality inputs via two levels of dynamic gating: inner-modality gates emphasize salient regions within each modality, whereas modality-level gates re-weight whole streams; both are conditioned on the text instruction to adaptively balance modality importance. Our UniMVU combines cross-modal self-attention with instruction-driven inner-modality gating module and a modality-level gating module with control token; for time-aligned streams we further adopt a fast-to-slow fusion scheme that reduces redundancy. Across six benchmarks (AVQA, AVSD, Music-AVQA, ScanQA, SQA3D and MVBench), our UniMVU achieves consistent gains over static-fusion baselines achieving gains as high as 13.5 in terms of CIDEr metric. Further, our analysis shows that the gating mechanism aligns with the human-interpretable modality relevance, and ablations show the contributions of inner-modality and modality-level gating. Our UniMVU provides a simple, unified recipe for instruction-aware multimodal video understanding that scales to diverse modalities without hand-crafted fusion rules.

Sofiat Abioye, Ufaq Khan, Shazad Ashraf et al.

Urgent suspected colorectal cancer (CRC) referrals create operational bottlenecks because semi-structured clinical documents often require manual review and transcription. The original RAPTOR system used Large Language Models for structured extraction but relied on a separate OCR stage, making it vulnerable to handwriting, layout variation, and loss of visual evidence linkage. We present RAPTOR+, a multimodal extension that uses Vision-Language Models (VLMs) for end-to-end referral understanding. We evaluate fine-tuned VLMs, commercial and open-source zero-shot VLMs, and the original OCR-based pipeline on 223 clinically curated CRC urgent referral forms. We also introduce a grounding-aware evaluation framework that measures both extraction accuracy and evidence localisation. Results show a clear grounding gap in zero-shot models. Gemini 2.5 Flash achieved 92.6% Reading Accuracy but only 1.2% Strict Safety. In contrast, fine-tuned Qwen3-VL-8B achieved 96.1% Reading Accuracy and 60.6% Strict Safety, substantially improving verifiable evidence grounding. These findings show that task-specific fine-tuning is essential for reliable, auditable clinical document understanding. RAPTOR+ enables extracted referral decisions to be linked to visual evidence, supporting safer and more efficient cancer referral triage.

L. D. M. S. Sai Teja, Ufaq Khan, Sathira Silva et al.

Post-training methods such as supervised fine-tuning (SFT) and preference optimization typically align language models toward a single global assistant behavior. While effective for improving average helpfulness, this can suppress the natural variation of human responses across languages, tasks, and dialogue settings. We study this problem as conditional human-distribution alignment: models should match the human response distribution appropriate to the current interaction context, rather than a universal response style. We introduce PolyAlign, a distribution-aware alignment framework that organizes bilingual interaction data into bucket-specific human reference distributions defined by language, interaction track, response family, and length. PolyAlign combines Bucket-Aware SFT, which balances optimization across heterogeneous buckets, with Human-Distribution Preference Optimization (HDPO), which regularizes preference learning using critic-estimated distance to bucket-specific human support. Across a bilingual evaluation suite covering English and Chinese single- and multi-turn settings, PolyAlign improves conditional naturalness and distributional faithfulness while preserving competitive task utility. The results suggest that post-training should move beyond global alignment objectives toward interaction-aware alignment with human response distributions.