Luyang Fang

Luyang Fang, Yongkai Chen, Jiazhang Cai et al.

Knowledge distillation is a powerful method for model compression, enabling the efficient deployment of complex deep learning models (teachers), including large language models. However, its underlying statistical mechanisms remain unclear, and uncertainty evaluation is often overlooked, especially in real-world scenarios requiring diverse teacher expertise. To address these challenges, we introduce \textit{Multi-Teacher Bayesian Knowledge Distillation} (MT-BKD), where a distilled student model learns from multiple teachers within the Bayesian framework. Our approach leverages Bayesian inference to capture inherent uncertainty in the distillation process. We introduce a teacher-informed prior, integrating external knowledge from teacher models and task-specific training data, offering better generalization, robustness, and scalability. Additionally, an entropy-based weighting mechanism adaptively adjusts each teacher's influence, allowing the student to combine multiple sources of expertise effectively. MT-BKD enhances the interpretability of the student model's learning process, improves predictive accuracy, and provides uncertainty quantification. We validate MT-BKD on both synthetic and real-world tasks, including protein subcellular location prediction and image classification. Our experiments show improved performance and robust uncertainty quantification, highlighting the strengths of our MT-BKD framework.

Luyang Fang, Gyeong-Geon Lee, Xiaoming Zhai

Machine learning-based automatic scoring faces challenges with unbalanced student responses across scoring categories. To address this, we introduce a novel text data augmentation framework leveraging GPT-4, a generative large language model, specifically tailored for unbalanced datasets in automatic scoring. Our experimental dataset comprised student written responses to four science items. We crafted prompts for GPT-4 to generate responses, especially for minority scoring classes, enhancing the data set. We then finetuned DistillBERT for automatic scoring based on the augmented and original datasets. Model performance was assessed using accuracy, precision, recall, and F1 metrics. Our findings revealed that incorporating GPT-4-augmented data remarkedly improved model performance, particularly for precision and F1 scores. Interestingly, the extent of improvement varied depending on the specific dataset and the proportion of augmented data used. Notably, we found that a varying amount of augmented data (20%-40%) was needed to obtain stable improvement for automatic scoring. Comparisons with models trained on additional student-written responses suggest that GPT-4 augmented models match those trained with student data. This research underscores the potential and effectiveness of data augmentation techniques utilizing generative large language models like GPT-4 in addressing unbalanced datasets within automated assessment.

Huimin Cheng, Xiaowei Yu, Shushan Wu et al.

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures through stochastic binary masking, they suffer from non-differentiability, training instability, and the inability to model complex community structure. We present DCMM-Transformer, a novel ViT architecture for medical image analysis that incorporates a Degree-Corrected Mixed-Membership (DCMM) model as an additive bias in self-attention. Unlike prior approaches that rely on multiplicative masking and binary sampling, our method introduces community structure and degree heterogeneity in a fully differentiable and interpretable manner. Comprehensive experiments across diverse medical imaging datasets, including brain, chest, breast, and ocular modalities, demonstrate the superior performance and generalizability of the proposed approach. Furthermore, the learned group structure and structured attention modulation substantially enhance interpretability by yielding attention maps that are anatomically meaningful and semantically coherent.

Haoran Lu, Luyang Fang, Wenxuan Zhong et al.

Multi-agent language systems are often built as hand-designed workflows, where agents are assigned semantic roles and communication protocols are specified in advance. We propose NeuroMAS, a method that first treats a multi-agent language system as a trainable and scalable neural-network-like architecture with LLM agents as nodes and intermediate textual signals as edges. In NeuroMAS, agent nodes are role-free but structure-aware: the topology only determines how information can flow in general, while reinforcement learning training determines how nodes communicate, specialize, and coordinate. This formulation shifts multi-agent design from workflow engineering toward architecture design, where depth, width, connectivity, and growth protocol become scalable sources of capability. Further, we provide a theoretical perspective showing why such modular textual computation is more parameter-efficient when tasks admit hierarchical decompositions. Experiments show that NeuroMAS improves significantly over both inference-time and trained multi-agent baselines. We further find that organizational scaling is path-dependent: larger systems can be challenging to train from scratch, but become feasible when grown progressively from smaller trained systems. These results suggest that learned neural multi-agent systems are a promising scaling axis for LLMs.

Ehsan Latif, Yifan Zhou, Shuchen Guo et al.

As artificial intelligence (AI) continues to advance, it demonstrates capabilities comparable to human intelligence, with significant potential to transform education and workforce development. This study evaluates OpenAI o1-preview's ability to perform higher-order cognitive tasks across 14 dimensions, including critical thinking, systems thinking, computational thinking, design thinking, metacognition, data literacy, creative thinking, abstract reasoning, quantitative reasoning, logical reasoning, analogical reasoning, and scientific reasoning. We used validated instruments like the Ennis-Weir Critical Thinking Essay Test and the Biological Systems Thinking Test to compare the o1-preview's performance with human performance systematically. Our findings reveal that o1-preview outperforms humans in most categories, achieving 150% better results in systems thinking, computational thinking, data literacy, creative thinking, scientific reasoning, and abstract reasoning. However, compared to humans, it underperforms by around 25% in logical reasoning, critical thinking, and quantitative reasoning. In analogical reasoning, both o1-preview and humans achieved perfect scores. Despite these strengths, the o1-preview shows limitations in abstract reasoning, where human psychology students outperform it, highlighting the continued importance of human oversight in tasks requiring high-level abstraction. These results have significant educational implications, suggesting a shift toward developing human skills that complement AI, such as creativity, abstract reasoning, and critical thinking. This study emphasizes the transformative potential of AI in education and calls for a recalibration of educational goals, teaching methods, and curricula to align with an AI-driven world.

Luyang Fang, Xiaowei Yu, Jiazhang Cai et al.

The exponential growth of Large Language Models (LLMs) continues to highlight the need for efficient strategies to meet ever-expanding computational and data demands. This survey provides a comprehensive analysis of two complementary paradigms: Knowledge Distillation (KD) and Dataset Distillation (DD), both aimed at compressing LLMs while preserving their advanced reasoning capabilities and linguistic diversity. We first examine key methodologies in KD, such as task-specific alignment, rationale-based training, and multi-teacher frameworks, alongside DD techniques that synthesize compact, high-impact datasets through optimization-based gradient matching, latent space regularization, and generative synthesis. Building on these foundations, we explore how integrating KD and DD can produce more effective and scalable compression strategies. Together, these approaches address persistent challenges in model scalability, architectural heterogeneity, and the preservation of emergent LLM abilities. We further highlight applications across domains such as healthcare and education, where distillation enables efficient deployment without sacrificing performance. Despite substantial progress, open challenges remain in preserving emergent reasoning and linguistic diversity, enabling efficient adaptation to continually evolving teacher models and datasets, and establishing comprehensive evaluation protocols. By synthesizing methodological innovations, theoretical foundations, and practical insights, our survey charts a path toward sustainable, resource-efficient LLMs through the tighter integration of KD and DD principles.

Wei Ruan, Yanjun Lyu, Jing Zhang et al.

With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications. This survey aims to address this need by providing a thorough review of BioLMs, focusing on their evolution, classification, and distinguishing features, alongside a detailed examination of training methodologies, datasets, and evaluation frameworks. We explore the wide-ranging applications of BioLMs in critical areas such as disease diagnosis, drug discovery, and vaccine development, highlighting their impact and transformative potential in bioinformatics. We identify key challenges and limitations inherent in BioLMs, including data privacy and security concerns, interpretability issues, biases in training data and model outputs, and domain adaptation complexities. Finally, we highlight emerging trends and future directions, offering valuable insights to guide researchers and clinicians toward advancing BioLMs for increasingly sophisticated biological and clinical applications.

Ehsan Latif, Luyang Fang, Ping Ma et al.

This study proposes a method for knowledge distillation (KD) of fine-tuned Large Language Models (LLMs) into smaller, more efficient, and accurate neural networks. We specifically target the challenge of deploying these models on resource-constrained devices. Our methodology involves training the smaller student model (Neural Network) using the prediction probabilities (as soft labels) of the LLM, which serves as a teacher model. This is achieved through a specialized loss function tailored to learn from the LLM's output probabilities, ensuring that the student model closely mimics the teacher's performance. To validate the performance of the KD approach, we utilized a large dataset, 7T, containing 6,684 student-written responses to science questions and three mathematical reasoning datasets with student-written responses graded by human experts. We compared accuracy with state-of-the-art (SOTA) distilled models, TinyBERT, and artificial neural network (ANN) models. Results have shown that the KD approach has 3% and 2% higher scoring accuracy than ANN and TinyBERT, respectively, and comparable accuracy to the teacher model. Furthermore, the student model size is 0.03M, 4,000 times smaller in parameters and x10 faster in inferencing than the teacher model and TinyBERT, respectively. The significance of this research lies in its potential to make advanced AI technologies accessible in typical educational settings, particularly for automatic scoring.

Haoran Lu, Luyang Fang, Ruidong Zhang et al.

Due to the remarkable capabilities and growing impact of large language models (LLMs), they have been deeply integrated into many aspects of society. Thus, ensuring their alignment with human values and intentions has emerged as a critical challenge. This survey provides a comprehensive overview of practical alignment techniques, training protocols, and empirical findings in LLM alignment. We analyze the development of alignment methods across diverse paradigms, characterizing the fundamental trade-offs between core alignment objectives. Our analysis shows that while supervised fine-tuning enables basic instruction-following, preference-based methods offer more flexibility for aligning with nuanced human intent. We discuss state-of-the-art techniques, including Direct Preference Optimization (DPO), Constitutional AI, brain-inspired methods, and alignment uncertainty quantification (AUQ), highlighting their approaches to balancing quality and efficiency. We review existing evaluation frameworks and benchmarking datasets, emphasizing limitations such as reward misspecification, distributional robustness, and scalable oversight. We summarize strategies adopted by leading AI labs to illustrate the current state of practice. We conclude by outlining open problems in oversight, value pluralism, robustness, and continuous alignment. This survey aims to inform both researchers and practitioners navigating the evolving landscape of LLM alignment.

Luyang Fang, Ehsan Latif, Haoran Lu et al.

Automatic scoring of student responses enhances efficiency in education, but deploying a separate neural network for each task increases storage demands, maintenance efforts, and redundant computations. To address these challenges, this paper introduces the Gromov-Wasserstein Scoring Model Merging (GW-SMM) method, which merges models based on feature distribution similarities measured via the Gromov-Wasserstein distance. Our approach begins by extracting features from student responses using individual models, capturing both item-specific context and unique learned representations. The Gromov-Wasserstein distance then quantifies the similarity between these feature distributions, identifying the most compatible models for merging. Models exhibiting the smallest pairwise distances, typically in pairs or trios, are merged by combining only the shared layers preceding the classification head. This strategy results in a unified feature extractor while preserving separate classification heads for item-specific scoring. We validated our approach against human expert knowledge and a GPT-o1-based merging method. GW-SMM consistently outperformed both, achieving a higher micro F1 score, macro F1 score, exact match accuracy, and per-label accuracy. The improvements in micro F1 and per-label accuracy were statistically significant compared to GPT-o1-based merging (p=0.04, p=0.01). Additionally, GW-SMM reduced storage requirements by half without compromising much accuracy, demonstrating its computational efficiency alongside reliable scoring performance.