Shinnosuke Ono

Shinnosuke Ono, Issey Sukeda, Takuro Fujii et al.

We present a Japanese domain-specific language model for the pharmaceutical field, developed through continual pretraining on 2 billion Japanese pharmaceutical tokens and 8 billion English biomedical tokens. To enable rigorous evaluation, we introduce three new benchmarks: YakugakuQA, based on national pharmacist licensing exams; NayoseQA, which tests cross-lingual synonym and terminology normalization; and SogoCheck, a novel task designed to assess consistency reasoning between paired statements. We evaluate our model against both open-source medical LLMs and commercial models, including GPT-4o. Results show that our domain-specific model outperforms existing open models and achieves competitive performance with commercial ones, particularly on terminology-heavy and knowledge-based tasks. Interestingly, even GPT-4o performs poorly on SogoCheck, suggesting that cross-sentence consistency reasoning remains an open challenge. Our benchmark suite offers a broader diagnostic lens for pharmaceutical NLP, covering factual recall, lexical variation, and logical consistency. This work demonstrates the feasibility of building practical, secure, and cost-effective language models for Japanese domain-specific applications, and provides reusable evaluation resources for future research in pharmaceutical and healthcare NLP. Our model, codes, and datasets are released at https://github.com/EQUES-Inc/pharma-LLM-eval.

Ryosuke Takanami, Petr Khrapchenkov, Shu Morikuni et al.

As robots transition from controlled settings to unstructured human environments, building generalist agents that can reliably follow natural language instructions remains a central challenge. Progress in robust mobile manipulation requires large-scale multimodal datasets that capture contact-rich and long-horizon tasks, yet existing resources lack synchronized force-torque sensing, hierarchical annotations, and explicit failure cases. We address this gap with the AIRoA MoMa Dataset, a large-scale real-world multimodal dataset for mobile manipulation. It includes synchronized RGB images, joint states, six-axis wrist force-torque signals, and internal robot states, together with a novel two-layer annotation schema of sub-goals and primitive actions for hierarchical learning and error analysis. The initial dataset comprises 25,469 episodes (approx. 94 hours) collected with the Human Support Robot (HSR) and is fully standardized in the LeRobot v2.1 format. By uniquely integrating mobile manipulation, contact-rich interaction, and long-horizon structure, AIRoA MoMa provides a critical benchmark for advancing the next generation of Vision-Language-Action models. The first version of our dataset is now available at https://huggingface.co/datasets/airoa-org/airoa-moma .

Shinnosuke Ono, Johannes Ackermann, Soichiro Nishimori et al.

Reward models (RMs) used in reinforcement learning from human feedback (RLHF) are vulnerable to reward hacking: as the policy maximizes a learned proxy reward, true quality plateaus or degrades. We make the assumption that reward hacking is often caused by flipped advantage signs: instead of reducing the likelihood of a bad response, a flipped sign causes the update to increase it. By considering an adversarial perturbation in the RM parameter space, we can derive a certified sign-preservation radius, which is the smallest perturbation that can flip the advantage sign during policy optimization. Based on this formulation, we propose Sign-Certified Policy Optimization (SignCert-PO), down-weighting non-robust completions in the policy gradient update. Unlike prior approaches that require multiple RMs or access to the RM training data, SignCert-PO is lightweight and operates purely at the policy optimization stage using only the RM parameters and on-policy completions. On TL;DR summarization and AlpacaFarm benchmarks, SignCert-PO consistently achieves a better win rate than baselines and reduces reward hacking.