Yanhua Zhao

Yanhua Zhao

Histopathology analysis relies on Hematoxylin and Eosin (H&E) staining, but fluorescence microscopy offers complementary information. Converting fluorescence images to H&E-like appearance can aid interpretation and integration with standard workflows. We present a Cycle-Consistent Adversarial Network (CycleGAN) approach for unpaired image-to-image translation from multi-channel fluorescence microscopy to pseudo H&E stained histopathology images. The method combines C01 and C02 fluorescence channels into RGB and learns a bidirectional mapping between fluorescence and H&E domains without paired training data. The architecture uses ResNet-based generators with residual blocks and PatchGAN discriminators, trained with adversarial, cycle-consistency, and identity losses. Experiments on fluorescence microscopy datasets show the model generates realistic pseudo H&E images that preserve morphological structures while adopting H&E-like color characteristics. This enables visualization of fluorescence data in a format familiar to pathologists and supports integration with existing H&E-based analysis pipelines.

Yanhua Zhao

Smart insoles equipped with pressure sensors, accelerometers, and gyroscopes offer a non-intrusive means of monitoring human gait and posture. We present an activity classification system based on a circular dilated convolutional neural network (CDCNN) that processes multi-modal time-series data from such insoles. The model operates on 160-frame windows with 24 channels (18 pressure, 3 accelerometer, 3 gyroscope axes), achieving 86.42% test accuracy in a subject-independent evaluation on a four-class task (Standing, Walking, Sitting, Tandem), compared with 87.83% for an extreme gradient-boosted tree (XGBoost) model trained on flattened data. Permutation feature importance reveals that inertial sensors (accelerometer and gyroscope) contribute substantially to discrimination. The approach is suitable for embedded deployment and real-time inference.

Yanhua Zhao

Early-exit neural networks enable adaptive inference by allowing predictions at intermediate layers, reducing computational cost. However, early exits often lack interpretability and may focus on different features than deeper layers, limiting trust and explainability. This paper presents Explanation-Guided Training (EGT), a multi-objective framework that improves interpretability and consistency in early-exit networks through attention-based regularization. EGT introduces an attention consistency loss that aligns early-exit attention maps with the final exit. The framework jointly optimizes classification accuracy and attention consistency through a weighted combination of losses. Experiments on a real-world image classification dataset demonstrate that EGT achieves up to 98.97% overall accuracy (matching baseline performance) with a 1.97x inference speedup through early exits, while improving attention consistency by up to 18.5% compared to baseline models. The proposed method provides more interpretable and consistent explanations across all exit points, making early-exit networks more suitable for explainable AI applications in resource-constrained environments.