Xiaofeng Liu

Xiaofeng Liu, Fangxu Xing, Nadya Shusharina et al. · cmu, harvard

Unsupervised domain adaptation (UDA) has been vastly explored to alleviate domain shifts between source and target domains, by applying a well-performed model in an unlabeled target domain via supervision of a labeled source domain. Recent literature, however, has indicated that the performance is still far from satisfactory in the presence of significant domain shifts. Nonetheless, delineating a few target samples is usually manageable and particularly worthwhile, due to the substantial performance gain. Inspired by this, we aim to develop semi-supervised domain adaptation (SSDA) for medical image segmentation, which is largely underexplored. We, thus, propose to exploit both labeled source and target domain data, in addition to unlabeled target data in a unified manner. Specifically, we present a novel asymmetric co-training (ACT) framework to integrate these subsets and avoid the domination of the source domain data. Following a divide-and-conquer strategy, we explicitly decouple the label supervisions in SSDA into two asymmetric sub-tasks, including semi-supervised learning (SSL) and UDA, and leverage different knowledge from two segmentors to take into account the distinction between the source and target label supervisions. The knowledge learned in the two modules is then adaptively integrated with ACT, by iteratively teaching each other, based on the confidence-aware pseudo-label. In addition, pseudo label noise is well-controlled with an exponential MixUp decay scheme for smooth propagation. Experiments on cross-modality brain tumor MRI segmentation tasks using the BraTS18 database showed, even with limited labeled target samples, ACT yielded marked improvements over UDA and state-of-the-art SSDA methods and approached an "upper bound" of supervised joint training.

Xiaofeng Liu, Chaehwa Yoo, Fangxu Xing et al. · cmu, harvard

Deep learning has become the method of choice to tackle real-world problems in different domains, partly because of its ability to learn from data and achieve impressive performance on a wide range of applications. However, its success usually relies on two assumptions: (i) vast troves of labeled datasets are required for accurate model fitting, and (ii) training and testing data are independent and identically distributed. Its performance on unseen target domains, thus, is not guaranteed, especially when encountering out-of-distribution data at the adaptation stage. The performance drop on data in a target domain is a critical problem in deploying deep neural networks that are successfully trained on data in a source domain. Unsupervised domain adaptation (UDA) is proposed to counter this, by leveraging both labeled source domain data and unlabeled target domain data to carry out various tasks in the target domain. UDA has yielded promising results on natural image processing, video analysis, natural language processing, time-series data analysis, medical image analysis, etc. In this review, as a rapidly evolving topic, we provide a systematic comparison of its methods and applications. In addition, the connection of UDA with its closely related tasks, e.g., domain generalization and out-of-distribution detection, has also been discussed. Furthermore, deficiencies in current methods and possible promising directions are highlighted.

Xiaofeng Liu, Fangxu Xing, Jia You et al. · cmu, harvard

Unsupervised domain adaptation (UDA) has been successfully applied to transfer knowledge from a labeled source domain to target domains without their labels. Recently introduced transferable prototypical networks (TPN) further addresses class-wise conditional alignment. In TPN, while the closeness of class centers between source and target domains is explicitly enforced in a latent space, the underlying fine-grained subtype structure and the cross-domain within-class compactness have not been fully investigated. To counter this, we propose a new approach to adaptively perform a fine-grained subtype-aware alignment to improve performance in the target domain without the subtype label in both domains. The insight of our approach is that the unlabeled subtypes in a class have the local proximity within a subtype, while exhibiting disparate characteristics, because of different conditional and label shifts. Specifically, we propose to simultaneously enforce subtype-wise compactness and class-wise separation, by utilizing intermediate pseudo-labels. In addition, we systematically investigate various scenarios with and without prior knowledge of subtype numbers, and propose to exploit the underlying subtype structure. Furthermore, a dynamic queue framework is developed to evolve the subtype cluster centroids steadily using an alternative processing scheme. Experimental results, carried out with multi-view congenital heart disease data and VisDA and DomainNet, show the effectiveness and validity of our subtype-aware UDA, compared with state-of-the-art UDA methods.

Jing Wang, Xiaofeng Liu, Fangyun Wang et al.

Congenital heart disease (CHD) is the most common birth defect and the leading cause of neonate death in China. Clinical diagnosis can be based on the selected 2D key-frames from five views. Limited by the availability of multi-view data, most methods have to rely on the insufficient single view analysis. This study proposes to automatically analyze the multi-view echocardiograms with a practical end-to-end framework. We collect the five-view echocardiograms video records of 1308 subjects (including normal controls, ventricular septal defect (VSD) patients and atrial septal defect (ASD) patients) with both disease labels and standard-view key-frame labels. Depthwise separable convolution-based multi-channel networks are adopted to largely reduce the network parameters. We also approach the imbalanced class problem by augmenting the positive training samples. Our 2D key-frame model can diagnose CHD or negative samples with an accuracy of 95.4\%, and in negative, VSD or ASD classification with an accuracy of 92.3\%. To further alleviate the work of key-frame selection in real-world implementation, we propose an adaptive soft attention scheme to directly explore the raw video data. Four kinds of neural aggregation methods are systematically investigated to fuse the information of an arbitrary number of frames in a video. Moreover, with a view detection module, the system can work without the view records. Our video-based model can diagnose with an accuracy of 93.9\% (binary classification), and 92.1\% (3-class classification) in a collected 2D video testing set, which does not need key-frame selection and view annotation in testing. The detailed ablation study and the interpretability analysis are provided.

Lingsheng Kong, Bo Hu, Xiongchang Liu et al. · cmu, harvard

Deep learning is usually data starved, and the unsupervised domain adaptation (UDA) is developed to introduce the knowledge in the labeled source domain to the unlabeled target domain. Recently, deep self-training presents a powerful means for UDA, involving an iterative process of predicting the target domain and then taking the confident predictions as hard pseudo-labels for retraining. However, the pseudo-labels are usually unreliable, thus easily leading to deviated solutions with propagated errors. In this paper, we resort to the energy-based model and constrain the training of the unlabeled target sample with an energy function minimization objective. It can be achieved via a simple additional regularization or an energy-based loss. This framework allows us to gain the benefits of the energy-based model, while retaining strong discriminative performance following a plug-and-play fashion. The convergence property and its connection with classification expectation minimization are investigated. We deliver extensive experiments on the most popular and large-scale UDA benchmarks of image classification as well as semantic segmentation to demonstrate its generality and effectiveness.

Jintang Xue, Yun-Cheng Wang, Chengwei Wei et al.

Chatbots have been studied for more than half a century. With the rapid development of natural language processing (NLP) technologies in recent years, chatbots using large language models (LLMs) have received much attention nowadays. Compared with traditional ones, modern chatbots are more powerful and have been used in real-world applications. There are however, bias and fairness concerns in modern chatbot design. Due to the huge amounts of training data, extremely large model sizes, and lack of interpretability, bias mitigation and fairness preservation of modern chatbots are challenging. Thus, a comprehensive overview on bias and fairness in chatbot systems is given in this paper. The history of chatbots and their categories are first reviewed. Then, bias sources and potential harms in applications are analyzed. Considerations in designing fair and unbiased chatbot systems are examined. Finally, future research directions are discussed.

Yongsong Huang, Tomo Miyazaki, Xiaofeng Liu et al.

Image Super-Resolution (SR) is essential for a wide range of computer vision and image processing tasks. Investigating infrared (IR) image (or thermal images) super-resolution is a continuing concern within the development of deep learning. This survey aims to provide a comprehensive perspective of IR image super-resolution, including its applications, hardware imaging system dilemmas, and taxonomy of image processing methodologies. In addition, the datasets and evaluation metrics in IR image super-resolution tasks are also discussed. Furthermore, the deficiencies in current technologies and possible promising directions for the community to explore are highlighted. To cope with the rapid development in this field, we intend to regularly update the relevant excellent work at https://github.com/yongsongH/Infrared_Image_SR_Survey.

Jiaqi Xu, Cheng Luo, Weicheng Xie et al.

Verbal and non-verbal human reaction generation is a challenging task, as different reactions could be appropriate for responding to the same behaviour. This paper proposes the first multiple and multimodal (verbal and nonverbal) appropriate human reaction generation framework that can generate appropriate and realistic human-style reactions (displayed in the form of synchronised text, audio and video streams) in response to an input user behaviour. This novel technique can be applied to various human-computer interaction scenarios by generating appropriate virtual agent/robot behaviours. Our demo is available at \url{https://github.com/SSYSteve/MRecGen}.

Chaopeng Shen, Alison P. Appling, Pierre Gentine et al.

Process-Based Modeling (PBM) and Machine Learning (ML) are often perceived as distinct paradigms in the geosciences. Here we present differentiable geoscientific modeling as a powerful pathway toward dissolving the perceived barrier between them and ushering in a paradigm shift. For decades, PBM offered benefits in interpretability and physical consistency but struggled to efficiently leverage large datasets. ML methods, especially deep networks, presented strong predictive skills yet lacked the ability to answer specific scientific questions. While various methods have been proposed for ML-physics integration, an important underlying theme -- differentiable modeling -- is not sufficiently recognized. Here we outline the concepts, applicability, and significance of differentiable geoscientific modeling (DG). "Differentiable" refers to accurately and efficiently calculating gradients with respect to model variables, critically enabling the learning of high-dimensional unknown relationships. DG refers to a range of methods connecting varying amounts of prior knowledge to neural networks and training them together, capturing a different scope than physics-guided machine learning and emphasizing first principles. Preliminary evidence suggests DG offers better interpretability and causality than ML, improved generalizability and extrapolation capability, and strong potential for knowledge discovery, while approaching the performance of purely data-driven ML. DG models require less training data while scaling favorably in performance and efficiency with increasing amounts of data. With DG, geoscientists may be better able to frame and investigate questions, test hypotheses, and discover unrecognized linkages.

Xiaofeng Liu, Chaehwa Yoo, Fangxu Xing et al.

Unsupervised domain adaptation (UDA) has been widely used to transfer knowledge from a labeled source domain to an unlabeled target domain to counter the difficulty of labeling in a new domain. The training of conventional solutions usually relies on the existence of both source and target domain data. However, privacy of the large-scale and well-labeled data in the source domain and trained model parameters can become the major concern of cross center/domain collaborations. In this work, to address this, we propose a practical solution to UDA for segmentation with a black-box segmentation model trained in the source domain only, rather than original source data or a white-box source model. Specifically, we resort to a knowledge distillation scheme with exponential mixup decay (EMD) to gradually learn target-specific representations. In addition, unsupervised entropy minimization is further applied to regularization of the target domain confidence. We evaluated our framework on the BraTS 2018 database, achieving performance on par with white-box source model adaptation approaches.

Saleh Afroogh, Seyd Ishtiaque Ahmed, Petra Ahrweiler et al. · cmu

This study provides a cross-disciplinary examination of Explainable Artificial Intelligence (XAI) approaches-focusing on deep neural networks (DNNs) and large language models (LLMs)-and identifies empirical and conceptual limitations in current XAI. We discuss critical symptoms that stem from deeper root causes (i.e., two paradoxes, two conceptual confusions, and five false assumptions). These fundamental problems within the current XAI research field reveal three insights: experimentally, XAI exhibits significant flaws; conceptually, it is paradoxical; and pragmatically, further attempts to reform the paradoxical XAI might exacerbate its confusion-demanding fundamental shifts and new research directions. To move beyond XAI's limitations, we propose a four-pronged synthesized paradigm shift toward reliable and certified AI development. These four components include: verification-focused Interactive AI (IAI) to establish scientific community protocols for certifying AI system performance rather than attempting post-hoc explanations, AI Epistemology for rigorous scientific foundations, User-Sensible AI to create context-aware systems tailored to specific user communities, and Model-Centered Interpretability for faithful technical analysis-together offering comprehensive post-XAI research directions.

Yongsong Huang, Tomo Miyazaki, Xiaofeng Liu et al.

Recent efforts have explored leveraging visible light images to enrich texture details in infrared (IR) super-resolution. However, this direct adaptation approach often becomes a double-edged sword, as it improves texture at the cost of introducing noise and blurring artifacts. To address these challenges, we propose the Target-oriented Domain Adaptation SRGAN (DASRGAN), an innovative framework specifically engineered for robust IR super-resolution model adaptation. DASRGAN operates on the synergy of two key components: 1) Texture-Oriented Adaptation (TOA) to refine texture details meticulously, and 2) Noise-Oriented Adaptation (NOA), dedicated to minimizing noise transfer. Specifically, TOA uniquely integrates a specialized discriminator, incorporating a prior extraction branch, and employs a Sobel-guided adversarial loss to align texture distributions effectively. Concurrently, NOA utilizes a noise adversarial loss to distinctly separate the generative and Gaussian noise pattern distributions during adversarial training. Our extensive experiments confirm DASRGAN's superiority. Comparative analyses against leading methods across multiple benchmarks and upsampling factors reveal that DASRGAN sets new state-of-the-art performance standards. Code are available at \url{https://github.com/yongsongH/DASRGAN}.

Xiaofeng Liu, Fangxu Xing, Hanna K. Gaggin et al.

Cardiac cine magnetic resonance imaging (MRI) has been used to characterize cardiovascular diseases (CVD), often providing a noninvasive phenotyping tool.~While recently flourished deep learning based approaches using cine MRI yield accurate characterization results, the performance is often degraded by small training samples. In addition, many deep learning models are deemed a ``black box," for which models remain largely elusive in how models yield a prediction and how reliable they are. To alleviate this, this work proposes a lightweight successive subspace learning (SSL) framework for CVD classification, based on an interpretable feedforward design, in conjunction with a cardiac atlas. Specifically, our hierarchical SSL model is based on (i) neighborhood voxel expansion, (ii) unsupervised subspace approximation, (iii) supervised regression, and (iv) multi-level feature integration. In addition, using two-phase 3D deformation fields, including end-diastolic and end-systolic phases, derived between the atlas and individual subjects as input offers objective means of assessing CVD, even with small training samples. We evaluate our framework on the ACDC2017 database, comprising one healthy group and four disease groups. Compared with 3D CNN-based approaches, our framework achieves superior classification performance with 140$\times$ fewer parameters, which supports its potential value in clinical use.

Kunlin Wu, Yanning Wang, Haofeng Tan et al.

Recent image-to-audio models have shown impressive performance on object-centric visual scenes. However, their application to satellite imagery remains limited by the complex, wide-area semantic ambiguity of top-down views. While satellite imagery provides a uniquely scalable source for global soundscape generation, matching these views to real acoustic environments with unique spatial structures is inherently difficult. To address this challenge, we introduce Geo2Sound, a novel task and framework for generating geographically realistic soundscapes from satellite imagery. Specifically, Geo2Sound combines structural geospatial attributes modeling, semantic hypothesis expansion, and geo-acoustic alignment in a unified framework. A lightweight classifier summarizes overhead scenes into compact geographic attributes, multiple sound-oriented semantic hypotheses are used to generate diverse acoustically plausible candidates, and a geo-acoustic alignment module projects geographic attributes into the acoustic embedding space and identifies the candidate most consistent with the candidate sets. Moreover, we establish SatSound-Bench, the first benchmark comprising over 20k high-quality paired satellite images, text descriptions, and real-world audio recordings, collected from the field across more than 10 countries and complemented by three public datasets. Experiments show that Geo2Sound achieves a SOTA FAD of 1.765, outperforming the strongest baseline by 50.0%. Human evaluations further confirm substantial gains in both realism (26.5%) and semantic alignment, validating our high-fidelity synthesis on scale. Project page and source code: https://github.com/Blanketzzz/Geo2Sound

Xiaofeng Liu, Fangxu Xing, Georges El Fakhri et al.

Unsupervised domain adaptation (UDA) has been a vital protocol for migrating information learned from a labeled source domain to facilitate the implementation in an unlabeled heterogeneous target domain. Although UDA is typically jointly trained on data from both domains, accessing the labeled source domain data is often restricted, due to concerns over patient data privacy or intellectual property. To sidestep this, we propose "off-the-shelf (OS)" UDA (OSUDA), aimed at image segmentation, by adapting an OS segmentor trained in a source domain to a target domain, in the absence of source domain data in adaptation. Toward this goal, we aim to develop a novel batch-wise normalization (BN) statistics adaptation framework. In particular, we gradually adapt the domain-specific low-order BN statistics, e.g., mean and variance, through an exponential momentum decay strategy, while explicitly enforcing the consistency of the domain shareable high-order BN statistics, e.g., scaling and shifting factors, via our optimization objective. We also adaptively quantify the channel-wise transferability to gauge the importance of each channel, via both low-order statistics divergence and a scaling factor.~Furthermore, we incorporate unsupervised self-entropy minimization into our framework to boost performance alongside a novel queued, memory-consistent self-training strategy to utilize the reliable pseudo label for stable and efficient unsupervised adaptation. We evaluated our OSUDA-based framework on both cross-modality and cross-subtype brain tumor segmentation and cardiac MR to CT segmentation tasks. Our experimental results showed that our memory consistent OSUDA performs better than existing source-relaxed UDA methods and yields similar performance to UDA methods with source data.

Xiaofeng Liu, Fangxu Xing, Maureen Stone et al.

The tongue's intricate 3D structure, comprising localized functional units, plays a crucial role in the production of speech. When measured using tagged MRI, these functional units exhibit cohesive displacements and derived quantities that facilitate the complex process of speech production. Non-negative matrix factorization-based approaches have been shown to estimate the functional units through motion features, yielding a set of building blocks and a corresponding weighting map. Investigating the link between weighting maps and speech acoustics can offer significant insights into the intricate process of speech production. To this end, in this work, we utilize two-dimensional spectrograms as a proxy representation, and develop an end-to-end deep learning framework for translating weighting maps to their corresponding audio waveforms. Our proposed plastic light transformer (PLT) framework is based on directional product relative position bias and single-level spatial pyramid pooling, thus enabling flexible processing of weighting maps with variable size to fixed-size spectrograms, without input information loss or dimension expansion. Additionally, our PLT framework efficiently models the global correlation of wide matrix input. To improve the realism of our generated spectrograms with relatively limited training samples, we apply pair-wise utterance consistency with Maximum Mean Discrepancy constraint and adversarial training. Experimental results on a dataset of 29 subjects speaking two utterances demonstrated that our framework is able to synthesize speech audio waveforms from weighting maps, outperforming conventional convolution and transformer models.

Xiaofeng Liu, Qianru Zhang, Thibault Marin et al.

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT remain largely task-specific, are often trained on single-center cohorts, or adopt dual-branch fusion schemes that delay cross-modal interaction and underutilize early spatial correspondence between PET and CT. To address these limitations, we present an open-source, multi-center, whole-body FDG PET/CT foundation model utilizing 4,997 harmonized scans from four public datasets. Our framework employs hierarchical UNet-shaped backbones with early channel-wise concatenation, enabling anatomical and metabolic features to interact from the first embedding layer onward. We further introduce a masked autoencoding objective based on zero-mean imputation, combined with a weighted global reconstruction loss. This design avoids non-physical intensity discontinuities at masked-region boundaries that arise from learnable mask tokens. On downstream AutoPET lesion segmentation, the proposed models demonstrate strong label efficiency: with only 10\% of the labeled training data, they achieve performance comparable to models trained from scratch on the full dataset. Under extreme 5-shot linear probing, joint PET/CT pretraining also achieves higher Dice scores than separated-modality pretraining. This multi-center foundation model demonstrates label efficiency and cross-modality representation learning for PET/CT tumor segmentation. It provides a robust, open-source basis for advancing automated oncologic imaging, significantly reducing the need for large-scale manual annotations in clinical practice.

Xiaofeng Liu, Yalan Song, Chaopeng Shen

River bathymetry is critical for many aspects of water resources management. We propose and demonstrate a bathymetry inversion method using a deep-learning-based surrogate for shallow water equations solvers. The surrogate uses the convolutional autoencoder with a shared-encoder, separate-decoder architecture. It encodes the input bathymetry and decodes to separate outputs for flow-field variables. A gradient-based optimizer is used to perform bathymetry inversion with the trained surrogate. Two physically-based constraints on both bed elevation value and slope have to be added as inversion loss regularizations to obtain usable inversion results. Using the "L-curve" criterion, a heuristic approach was proposed to determine the regularization parameters. Both the surrogate model and the inversion algorithm show good performance. We found the bathymetry inversion process has two distinctive stages, which resembles the sculptural process of initial broad-brush calving and final detailing. The inversion loss due to flow prediction error reaches its minimum in the first stage and remains almost constant afterward. The bed elevation value and slope regularizations play the dominant role in the second stage in selecting the most probable solution. We also found the surrogate architecture (whether with both velocity and water surface elevation or velocity only as outputs) does not show significant impact on inversion result.

Xiaofeng Liu, Fangxu Xing, Jerry L. Prince et al.

Investigating the relationship between internal tissue point motion of the tongue and oropharyngeal muscle deformation measured from tagged MRI and intelligible speech can aid in advancing speech motor control theories and developing novel treatment methods for speech related-disorders. However, elucidating the relationship between these two sources of information is challenging, due in part to the disparity in data structure between spatiotemporal motion fields (i.e., 4D motion fields) and one-dimensional audio waveforms. In this work, we present an efficient encoder-decoder translation network for exploring the predictive information inherent in 4D motion fields via 2D spectrograms as a surrogate of the audio data. Specifically, our encoder is based on 3D convolutional spatial modeling and transformer-based temporal modeling. The extracted features are processed by an asymmetric 2D convolution decoder to generate spectrograms that correspond to 4D motion fields. Furthermore, we incorporate a generative adversarial training approach into our framework to further improve synthesis quality on our generated spectrograms. We experiment on 63 paired motion field sequences and speech waveforms, demonstrating that our framework enables the generation of clear audio waveforms from a sequence of motion fields. Thus, our framework has the potential to improve our understanding of the relationship between these two modalities and inform the development of treatments for speech disorders.

Xiaofeng Liu, Fangxu Xing, Jerry L. Prince et al.

Understanding the underlying relationship between tongue and oropharyngeal muscle deformation seen in tagged-MRI and intelligible speech plays an important role in advancing speech motor control theories and treatment of speech related-disorders. Because of their heterogeneous representations, however, direct mapping between the two modalities -- i.e., two-dimensional (mid-sagittal slice) plus time tagged-MRI sequence and its corresponding one-dimensional waveform -- is not straightforward. Instead, we resort to two-dimensional spectrograms as an intermediate representation, which contains both pitch and resonance, from which to develop an end-to-end deep learning framework to translate from a sequence of tagged-MRI to its corresponding audio waveform with limited dataset size.~Our framework is based on a novel fully convolutional asymmetry translator with guidance of a self residual attention strategy to specifically exploit the moving muscular structures during speech.~In addition, we leverage a pairwise correlation of the samples with the same utterances with a latent space representation disentanglement strategy.~Furthermore, we incorporate an adversarial training approach with generative adversarial networks to offer improved realism on our generated spectrograms.~Our experimental results, carried out with a total of 63 tagged-MRI sequences alongside speech acoustics, showed that our framework enabled the generation of clear audio waveforms from a sequence of tagged-MRI, surpassing competing methods. Thus, our framework provides the great potential to help better understand the relationship between the two modalities.

Xiaofeng Liu, Jun Zhang, Fang-Wei Fu

Motivated by the studies of twisted generalized Reed-Solomon (TGRS) codes, we initiate the study of twisted elliptic curve codes (TECCs) in this paper. In particular, we study a class of TECCs with one twist. The parity-check matrices of the TECCs are explicitly given by computing the Weil differentials. Then the sufficient and necessary conditions of self-duality are presented. The minimum distances of the TECCs are also determined. Moreover, examples of MDS, AMDS, self-dual and MDS self-dual TECCs are given. Finally, we calculate the dimensions of the Schur squares of TECCs and show the non-equivalence between TECCs and ECCs/GRS codes.

Xiaofeng Liu, Jun Zhang, Fang-Wei Fu

Motivated by the constructions of binary sequences by utilizing the cyclic elliptic function fields over the finite field $\mathbb{F}_{2^{n}}$ by Jin \textit{et al.} in [IEEE Trans. Inf. Theory 71(8), 2025], we extend the construction to the cyclic elliptic function fields with odd characteristic by using the quadratic residue map $η$ instead of the trace map used therein. For any cyclic elliptic function field with $q+1+t$ rational points and any positive integer $d$ with $\gcd(d, q+1+t)=1$, we construct a new family of binary sequences of length $q+1+t$, size $q^{d-1}-1$, balance upper bounded by $(d+1)\cdot\lfloor2\sqrt{q}\rfloor+|t|+d,$ the correlation upper bounded by $(2d+1)\cdot\lfloor2\sqrt{q}\rfloor+|t|+2d$ and the linear complexity lower bounded by $\frac{q+1+2t-d-(d+1)\cdot\lfloor2\sqrt{q}\rfloor}{d+d\cdot\lfloor2\sqrt{q}\rfloor}$ where $\lfloor x\rfloor$ stands for the integer part of $x\in\mathbb{R}$.

Carson Dudley, Yutong Bi, Xiaofeng Liu et al.

Non-stationary sequences arise naturally in control, forecasting, and decision-making. The data-generating process shifts at unknown times, and models must detect the change, discard or downweight obsolete evidence, and adapt to new dynamics on the fly. Transformer-based foundation models increasingly rely on in-context learning for time series forecasting, tabular prediction, and continuous control. As these models are deployed in non-stationary environments, understanding their ability to detect and adapt to regime shifts is important. We formalize this as an in-context change-point detection problem and formally establish the existence of transformer models that solve this problem. Our construction demonstrates that model complexity, in layers and parameters, depends on the level of information available about the change-point location, from no knowledge to knowing exact timing. We validate our results with experiments on synthetic linear regression and linear dynamical systems, where trained transformers match the performance of optimal baselines across information levels. We also show that encoding and incorporating changepoint knowledge indeed improves the real-world performance of a pretrained foundation models on infectious disease forecasting and on financial volatility forecasting around Federal Open Market Committee (FOMC) announcements without retraining, demonstrating practical applicability to real-world regime changes.

Xiaofeng Liu, Qing Wang, Yunfeng Shao et al.

Federated learning (FL) can achieve privacy-safe and reliable collaborative training without collecting users' private data. Its excellent privacy security potential promotes a wide range of FL applications in Internet-of-Things (IoT), wireless networks, mobile devices, autonomous vehicles, and cloud medical treatment. However, the FL method suffers from poor model performance on non-i.i.d. data and excessive traffic volume. To this end, we propose a personalized FL algorithm using a hierarchical proximal mapping based on the moreau envelop, named sparse federated learning with hierarchical personalized models (sFedHP), which significantly improves the global model performance facing diverse data. A continuously differentiable approximated L1-norm is also used as the sparse constraint to reduce the communication cost. Convergence analysis shows that sFedHP's convergence rate is state-of-the-art with linear speedup and the sparse constraint only reduces the convergence rate to a small extent while significantly reducing the communication cost. Experimentally, we demonstrate the benefits of sFedHP compared with the FedAvg, HierFAVG (hierarchical FedAvg), and personalized FL methods based on local customization, including FedAMP, FedProx, Per-FedAvg, pFedMe, and pFedGP.

Xiaofeng Liu, Jonghye Woo, Chao Ma et al.

Delineating lesions and anatomical structure is important for image-guided interventions. Point-supervised medical image segmentation (PSS) has great potential to alleviate costly expert delineation labeling. However, due to the lack of precise size and boundary guidance, the effectiveness of PSS often falls short of expectations. Although recent vision foundational models, such as the medical segment anything model (MedSAM), have made significant advancements in bounding-box-prompted segmentation, it is not straightforward to utilize point annotation, and is prone to semantic ambiguity. In this preliminary study, we introduce an iterative framework to facilitate semantic-aware point-supervised MedSAM. Specifically, the semantic box-prompt generator (SBPG) module has the capacity to convert the point input into potential pseudo bounding box suggestions, which are explicitly refined by the prototype-based semantic similarity. This is then succeeded by a prompt-guided spatial refinement (PGSR) module that harnesses the exceptional generalizability of MedSAM to infer the segmentation mask, which also updates the box proposal seed in SBPG. Performance can be progressively improved with adequate iterations. We conducted an evaluation on BraTS2018 for the segmentation of whole brain tumors and demonstrated its superior performance compared to traditional PSS methods and on par with box-supervised methods.

Xiaofeng Liu, Thibault Marin, Tiss Amal et al.

Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging parameters, which in turn can be used to derive the most probable parameters as well as their uncertainties. Methods: Our deep learning-based approaches are based on a variational Bayesian inference framework, which is implemented using two different deep neural networks based on conditional variational auto-encoder (CVAE), CVAE-dual-encoder and CVAE-dual-decoder. The conventional CVAE framework, i.e., CVAE-vanilla, can be regarded as a simplified case of these two neural networks. We applied these approaches to a simulation study of dynamic brain PET imaging using a reference region-based kinetic model. Results: In the simulation study, we estimated posterior distributions of PET kinetic parameters given a measurement of time-activity curve. Our proposed CVAE-dual-encoder and CVAE-dual-decoder yield results that are in good agreement with the asymptotically unbiased posterior distributions sampled by Markov Chain Monte Carlo (MCMC). The CVAE-vanilla can also be used for estimating posterior distributions, although it has an inferior performance to both CVAE-dual-encoder and CVAE-dual-decoder. Conclusions: We have evaluated the performance of our deep learning approaches for estimating posterior distributions in dynamic brain PET. Our deep learning approaches yield posterior distributions, which are in good agreement with unbiased distributions estimated by MCMC. All these neural networks have different characteristics and can be chosen by the user for specific applications. The proposed methods are general and can be adapted to other problems.

Jihoon Cho, Suhyun Ahn, Beomju Kim et al.

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant challenge in many clinical applications. To address this issue, in this work, we propose a novel 3D brain segmentation approach using complementary 2D diffusion models. The core idea behind our approach is to first mine 2D features with semantic information extracted from the 2D diffusion models by taking orthogonal views as input, followed by fusing them into a 3D contextual feature representation. Then, we use these aggregated features to train multi-layer perceptrons to classify the segmentation labels. Our goal is to achieve reliable segmentation quality without requiring complete labels for each individual subject. Our experiments on training in brain subcortical structure segmentation with a dataset from only one subject demonstrate that our approach outperforms state-of-the-art self-supervised learning methods. Further experiments on the minimum requirement of annotation by sparse labeling yield promising results even with only nine slices and a labeled background region.

Qing Wang, Jing Jin, Xiaofeng Liu et al.

Federated learning (FL) is a new distributed machine learning framework that can achieve reliably collaborative training without collecting users' private data. However, due to FL's frequent communication and average aggregation strategy, they experience challenges scaling to statistical diversity data and large-scale models. In this paper, we propose a personalized FL framework, named Tensor Decomposition based Personalized Federated learning (TDPFed), in which we design a novel tensorized local model with tensorized linear layers and convolutional layers to reduce the communication cost. TDPFed uses a bi-level loss function to decouple personalized model optimization from the global model learning by controlling the gap between the personalized model and the tensorized local model. Moreover, an effective distributed learning strategy and two different model aggregation strategies are well designed for the proposed TDPFed framework. Theoretical convergence analysis and thorough experiments demonstrate that our proposed TDPFed framework achieves state-of-the-art performance while reducing the communication cost.

Xiaofeng Liu, Thibault Marin, Tiss Amal et al.

This work aims efficiently estimating the posterior distribution of kinetic parameters for dynamic positron emission tomography (PET) imaging given a measurement of time of activity curve. Considering the inherent information loss from parametric imaging to measurement space with the forward kinetic model, the inverse mapping is ambiguous. The conventional (but expensive) solution can be the Markov Chain Monte Carlo (MCMC) sampling, which is known to produce unbiased asymptotical estimation. We propose a deep-learning-based framework for efficient posterior estimation. Specifically, we counteract the information loss in the forward process by introducing latent variables. Then, we use a conditional variational autoencoder (CVAE) and optimize its evidence lower bound. The well-trained decoder is able to infer the posterior with a given measurement and the sampled latent variables following a simple multivariate Gaussian distribution. We validate our CVAE-based method using unbiased MCMC as the reference for low-dimensional data (a single brain region) with the simplified reference tissue model.

Huili Cai, Xiang Zhang, Xiaofeng Liu

Time series classification is a critical task in various domains, such as finance, healthcare, and sensor data analysis. Unsupervised contrastive learning has garnered significant interest in learning effective representations from time series data with limited labels. The prevalent approach in existing contrastive learning methods consists of two separate stages: pre-training the encoder on unlabeled datasets and fine-tuning the well-trained model on a small-scale labeled dataset. However, such two-stage approaches suffer from several shortcomings, such as the inability of unsupervised pre-training contrastive loss to directly affect downstream fine-tuning classifiers, and the lack of exploiting the classification loss which is guided by valuable ground truth. In this paper, we propose an end-to-end model called SLOTS (Semi-supervised Learning fOr Time clasSification). SLOTS receives semi-labeled datasets, comprising a large number of unlabeled samples and a small proportion of labeled samples, and maps them to an embedding space through an encoder. We calculate not only the unsupervised contrastive loss but also measure the supervised contrastive loss on the samples with ground truth. The learned embeddings are fed into a classifier, and the classification loss is calculated using the available true labels. The unsupervised, supervised contrastive losses and classification loss are jointly used to optimize the encoder and classifier. We evaluate SLOTS by comparing it with ten state-of-the-art methods across five datasets. The results demonstrate that SLOTS is a simple yet effective framework. When compared to the two-stage framework, our end-to-end SLOTS utilizes the same input data, consumes a similar computational cost, but delivers significantly improved performance. We release code and datasets at https://anonymous.4open.science/r/SLOTS-242E.

Xiaofeng Liu, Menghua Xia, Yanis Chemli et al.

In this work, we propose an unsupervised domain adaptation (UDA) framework for 3D volumetric lesion detection that adapts a detector trained on labeled FDG PET/CT to unlabeled PSMA PET/CT. Beyond covariate shift, cross tracer adaptation also exhibits label shift in both lesion size composition and the number of lesions per subject. We introduce self-training with two mechanisms that explicitly model and compensate for this label shift. First, we adaptively adjust the detection anchor shapes by re-estimating target domain box scales from selected pseudo labels and updating anchors with an exponential moving average. This increases positive anchor coverage for small PSMA lesions and stabilizes box regression. Second, instead of a fixed confidence threshold for pseudo-label selection, we allocate size bin-wise quotas according to the estimated target domain histogram over lesion volumes. The self-training alternates between supervised learning with prior-guided pseudo labeling on PSMA and supervised learning on labeled FDG. On AutoPET 2024, adapting from 501 labeled FDG studies to 369 $^{18}$F-PSMA studies, the proposed method improves both AP and FROC over the source-only baseline and conventional self-training without label-shift mitigation, indicating that modeling target lesion prevalence and size composition is an effective path to robust cross-tracer detection.

Weiwei Ma, Xiaobing Yu, Peijie Qiu et al.

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such diverse data, often sacrificing either generalization or domain-specific knowledge. To overcome these challenges, we propose a joint training method called Universal Harmonization (U-Harmony), which can be integrated into deep learning-based architectures with a domain-gated head, enabling a single segmentation model to learn from heterogeneous datasets simultaneously. By integrating U-Harmony, our approach sequentially normalizes and then denormalizes feature distributions to mitigate domain-specific variations while preserving original dataset-specific knowledge. More appealingly, our framework also supports universal modality adaptation, allowing the seamless learning of new imaging modalities and anatomical classes. Extensive experiments on cross-institutional brain lesion datasets demonstrate the effectiveness of our approach, establishing a new benchmark for robust and adaptable 3D medical image segmentation models in real-world clinical settings.

Yongsong Huang, Wanqing Xie, Mingzhen Li et al.

Federated learning (FL) enables multiple client medical institutes collaboratively train a deep learning (DL) model with privacy protection. However, the performance of FL can be constrained by the limited availability of labeled data in small institutes and the heterogeneous (i.e., non-i.i.d.) data distribution across institutes. Though data augmentation has been a proven technique to boost the generalization capabilities of conventional centralized DL as a "free lunch", its application in FL is largely underexplored. Notably, constrained by costly labeling, 3D medical segmentation generally relies on data augmentation. In this work, we aim to develop a vicinal feature-level data augmentation (VFDA) scheme to efficiently alleviate the local feature shift and facilitate collaborative training for privacy-aware FL segmentation. We take both the inner- and inter-institute divergence into consideration, without the need for cross-institute transfer of raw data or their mixup. Specifically, we exploit the batch-wise feature statistics (e.g., mean and standard deviation) in each institute to abstractly represent the discrepancy of data, and model each feature statistic probabilistically via a Gaussian prototype, with the mean corresponding to the original statistic and the variance quantifying the augmentation scope. From the vicinal risk minimization perspective, novel feature statistics can be drawn from the Gaussian distribution to fulfill augmentation. The variance is explicitly derived by the data bias in each individual institute and the underlying feature statistics characterized by all participating institutes. The added-on VFDA consistently yielded marked improvements over six advanced FL methods on both 3D brain tumor and cardiac segmentation.

Yongsong Huang, Tomo Miyazaki, Xiaofeng Liu et al.

Infrared image super-resolution demands long-range dependency modeling and multi-scale feature extraction to address challenges such as homogeneous backgrounds, weak edges, and sparse textures. While Mamba-based state-space models (SSMs) excel in global dependency modeling with linear complexity, their block-wise processing disrupts spatial consistency, limiting their effectiveness for IR image reconstruction. We propose IRSRMamba, a novel framework integrating wavelet transform feature modulation for multi-scale adaptation and an SSMs-based semantic consistency loss to restore fragmented contextual information. This design enhances global-local feature fusion, structural coherence, and fine-detail preservation while mitigating block-induced artifacts. Experiments on benchmark datasets demonstrate that IRSRMamba outperforms state-of-the-art methods in PSNR, SSIM, and perceptual quality. This work establishes Mamba-based architectures as a promising direction for high-fidelity IR image enhancement. Code are available at https://github.com/yongsongH/IRSRMamba.

Yuan Zhao, Youwei Pang, Jiaming Zuo et al.

Recent progress in promptable segmentation has shifted visual perception from object-level localization toward concept-level understanding. However, the notion of a concept remains under-specified, making it unclear whether current methods truly generalize beyond category recognition. In this work, we formalize generalized concept segmentation through a three-level taxonomy consisting of context-independent (CI), context-dependent (CD), and context-reasoning (CR) concepts, which reveals a clear capability gap across increasing levels of cognitive complexity. To address this challenge, we propose ConceptSeg-R1, a unified framework that reformulates concept segmentation as rule-induced concept grounding. At the core of our method is Meta-GRPO, a meta-reinforcement learning mechanism that learns transferable task rules from visual demonstrations and verifies them through proxy reasoning. The inferred reasoning states are then translated into segmentation-ready concept prompts via a lightweight concept translation module, enabling deductive application to target images. A shortcut routing strategy further preserves the native efficiency of segmentation models on simple cases. To systematically evaluate generalized concept segmentation, we conduct extensive experiments across diverse CI, CD, and CR concept segmentation benchmarks spanning natural, industrial, medical and reasoning-intensive domains. Without bells and whistles, ConceptSeg-R1 achieves strong performance across the full concept hierarchy while maintaining the native capability of promptable segmentation backbones. As an initial step toward segmenting any concept, we hope ConceptSeg-R1 can serve as a practical baseline for advancing segmentation from object-level prediction toward concept-level understanding.

Xu Han, Linghao Jin, Xuezhe Ma et al.

Fine-tuning pre-trained Vision-Language Models (VLMs) has shown remarkable capabilities in medical image and textual depiction synergy. Nevertheless, many pre-training datasets are restricted by patient privacy concerns, potentially containing noise that can adversely affect downstream performance. Moreover, the growing reliance on multi-modal generation exacerbates this issue because of its susceptibility to adversarial attacks. To investigate how VLMs trained on adversarial noisy data perform on downstream medical tasks, we first craft noisy upstream datasets using multi-modal adversarial attacks. Through our comprehensive analysis, we unveil that moderate noise enhances model robustness and transferability, but increasing noise levels negatively impact downstream task performance. To mitigate this issue, we propose rectify adversarial noise (RAN) framework, a recipe designed to effectively defend adversarial attacks and rectify the influence of upstream noise during fine-tuning.

Xiaoqi Zhao, Youwei Pang, Chenyang Yu et al.

Multi-modal image segmentation faces real-world deployment challenges from incomplete/corrupted modalities degrading performance. While existing methods address training-inference modality gaps via specialized per-combination models, they introduce high deployment costs by requiring exhaustive model subsets and model-modality matching. In this work, we propose a unified modality-relax segmentation network (UniMRSeg) through hierarchical self-supervised compensation (HSSC). Our approach hierarchically bridges representation gaps between complete and incomplete modalities across input, feature and output levels. % First, we adopt modality reconstruction with the hybrid shuffled-masking augmentation, encouraging the model to learn the intrinsic modality characteristics and generate meaningful representations for missing modalities through cross-modal fusion. % Next, modality-invariant contrastive learning implicitly compensates the feature space distance among incomplete-complete modality pairs. Furthermore, the proposed lightweight reverse attention adapter explicitly compensates for the weak perceptual semantics in the frozen encoder. Last, UniMRSeg is fine-tuned under the hybrid consistency constraint to ensure stable prediction under all modality combinations without large performance fluctuations. Without bells and whistles, UniMRSeg significantly outperforms the state-of-the-art methods under diverse missing modality scenarios on MRI-based brain tumor segmentation, RGB-D semantic segmentation, RGB-D/T salient object segmentation. The code will be released at https://github.com/Xiaoqi-Zhao-DLUT/UniMRSeg.

Yongsong Huang, Tomo Miyazaki, Xiaofeng Liu et al.

Infrared Image Super-Resolution (IRSR) is challenged by the low contrast and sparse textures of infrared data, requiring robust long-range modeling to maintain global coherence. While State-Space Models like Mamba offer proficiency in modeling long-range dependencies for this task, their inherent 1D causal scanning mechanism fragments the global context of 2D images, hindering fine-detail restoration. To address this, we propose Global Phase and Spectral Prompt-guided Mamba (GPSMamba), a framework that synergizes architectural guidance with non-causal supervision. First, our Adaptive Semantic-Frequency State Space Module (ASF-SSM) injects a fused semantic-frequency prompt directly into the Mamba block, integrating non-local context to guide reconstruction. Then, a novel Thermal-Spectral Attention and Phase Consistency Loss provides explicit, non-causal supervision to enforce global structural and spectral fidelity. By combining these two innovations, our work presents a systematic strategy to mitigate the limitations of causal modeling. Extensive experiments demonstrate that GPSMamba achieves state-of-the-art performance, validating our approach as a powerful new paradigm for infrared image restoration. Code is available at https://github.com/yongsongH/GPSMamba.

Nhan Ho, Luu Le, Thanh-Huy Nguyen et al.

Occlusion, where target structures are partially hidden by surgical instruments or overlapping tissues, remains a critical yet underexplored challenge for foundation segmentation models in clinical endoscopy. We introduce OccSAM-Bench, a benchmark designed to systematically evaluate SAM-family models under controlled, synthesized surgical occlusion. Our framework simulates two occlusion types (i.e., surgical tool overlay and cutout) across three calibrated severity levels on three public polyp datasets. We propose a novel three-region evaluation protocol that decomposes segmentation performance into full, visible-only, and invisible targets. This metric exposes behaviors that standard amodal evaluation obscures, revealing two distinct model archetypes: Occluder-Aware models (SAM, SAM 2, SAM 3, MedSAM3), which prioritize visible tissue delineation and reject instruments, and Occluder-Agnostic models (MedSAM, MedSAM2), which confidently predict into occluded regions. SAM-Med2D aligns with neither and underperforms across all conditions. Ultimately, our results demonstrate that occlusion robustness is not uniform across architectures, and model selection must be driven by specific clinical intent-whether prioritizing conservative visible-tissue segmentation or the amodal inference of hidden anatomy.

Xingsheng Chen, Regina Zhang, Bo Gao et al.

Time series prediction plays a pivotal role across diverse domains such as finance, healthcare, energy systems, and environmental modeling. However, existing approaches often struggle to balance efficiency, scalability, and accuracy, particularly when handling long-range dependencies and irregularly sampled data. To address these challenges, we propose MODE, a unified framework that integrates Low-Rank Neural Ordinary Differential Equations (Neural ODEs) with an Enhanced Mamba architecture. As illustrated in our framework, the input sequence is first transformed by a Linear Tokenization Layer and then processed through multiple Mamba Encoder blocks, each equipped with an Enhanced Mamba Layer that employs Causal Convolution, SiLU activation, and a Low-Rank Neural ODE enhancement to efficiently capture temporal dynamics. This low-rank formulation reduces computational overhead while maintaining expressive power. Furthermore, a segmented selective scanning mechanism, inspired by pseudo-ODE dynamics, adaptively focuses on salient subsequences to improve scalability and long-range sequence modeling. Extensive experiments on benchmark datasets demonstrate that MODE surpasses existing baselines in both predictive accuracy and computational efficiency. Overall, our contributions include: (1) a unified and efficient architecture for long-term time series modeling, (2) integration of Mamba's selective scanning with low-rank Neural ODEs for enhanced temporal representation, and (3) substantial improvements in efficiency and scalability enabled by low-rank approximation and dynamic selective scanning.

Ziyao Zeng, Chen Liu, Tianyu Liu et al.

Game balancing is a longstanding challenge requiring repeated playtesting, expert intuition, and extensive manual tuning. We introduce RuleSmith, the first framework that achieves automated game balancing by leveraging the reasoning capabilities of multi-agent LLMs. It couples a game engine, multi-agent LLMs self-play, and Bayesian optimization operating over a multi-dimensional rule space. As a proof of concept, we instantiate RuleSmith on CivMini, a simplified civilization-style game containing heterogeneous factions, economy systems, production rules, and combat mechanics, all governed by tunable parameters. LLM agents interpret textual rulebooks and game states to generate actions, to conduct fast evaluation of balance metrics such as win-rate disparities. To search the parameter landscape efficiently, we integrate Bayesian optimization with acquisition-based adaptive sampling and discrete projection: promising candidates receive more evaluation games for accurate assessment, while exploratory candidates receive fewer games for efficient exploration. Experiments show that RuleSmith converges to highly balanced configurations and provides interpretable rule adjustments that can be directly applied to downstream game systems. Our results illustrate that LLM simulation can serve as a powerful surrogate for automating design and balancing in complex multi-agent environments.

Youwei Pang, Xiaoqi Zhao, Lihe Zhang et al.

As an essential vision task, infrared small target detection (IRSTD) has seen significant advancements through deep learning. However, critical limitations in current evaluation protocols impede further progress. First, existing methods rely on fragmented pixel- and target-level specific metrics, which fails to provide a comprehensive view of model capabilities. Second, an excessive emphasis on overall performance scores obscures crucial error analysis, which is vital for identifying failure modes and improving real-world system performance. Third, the field predominantly adopts dataset-specific training-testing paradigms, hindering the understanding of model robustness and generalization across diverse infrared scenarios. This paper addresses these issues by introducing a hybrid-level metric incorporating pixel- and target-level performance, proposing a systematic error analysis method, and emphasizing the importance of cross-dataset evaluation. These aim to offer a more thorough and rational hierarchical analysis framework, ultimately fostering the development of more effective and robust IRSTD models. An open-source toolkit has be released to facilitate standardized benchmarking.

Xiaoqi Zhao, Peiqian Cao, Chenyang Yu et al.

Power batteries are essential components in electric vehicles, where internal structural defects can pose serious safety risks. We conduct a comprehensive study on a new task, power battery detection (PBD), which aims to localize the dense endpoints of cathode and anode plates from industrial X-ray images for quality inspection. Manual inspection is inefficient and error-prone, while traditional vision algorithms struggle with densely packed plates, low contrast, scale variation, and imaging artifacts. To address this issue and drive more attention into this meaningful task, we present PBD5K, the first large-scale benchmark for this task, consisting of 5,000 X-ray images from nine battery types with fine-grained annotations and eight types of real-world visual interference. To support scalable and consistent labeling, we develop an intelligent annotation pipeline that combines image filtering, model-assisted pre-labeling, cross-verification, and layered quality evaluation. We formulate PBD as a point-level segmentation problem and propose MDCNeXt, a model designed to extract and integrate multi-dimensional structure clues including point, line, and count information from the plate itself. To improve discrimination between plates and suppress visual interference, MDCNeXt incorporates two state space modules. The first is a prompt-filtered module that learns contrastive relationships guided by task-specific prompts. The second is a density-aware reordering module that refines segmentation in regions with high plate density. In addition, we propose a distance-adaptive mask generation strategy to provide robust supervision under varying spatial distributions of anode and cathode positions. The source code and datasets will be publicly available at \href{https://github.com/Xiaoqi-Zhao-DLUT/X-ray-PBD}{PBD5K}.

Pujun Xue, Junyi Ge, Xiaotong Jiang et al.

Malocclusion is a major challenge in orthodontics, and its complex presentation and diverse clinical manifestations make accurate localization and diagnosis particularly important. Currently, one of the major shortcomings facing the field of dental image analysis is the lack of large-scale, accurately labeled datasets dedicated to malocclusion issues, which limits the development of automated diagnostics in the field of dentistry and leads to a lack of diagnostic accuracy and efficiency in clinical practice. Therefore, in this study, we propose the Oral and Maxillofacial Natural Images (OMNI) dataset, a novel and comprehensive dental image dataset aimed at advancing the study of analyzing dental images for issues of malocclusion. Specifically, the dataset contains 4166 multi-view images with 384 participants in data collection and annotated by professional dentists. In addition, we performed a comprehensive validation of the created OMNI dataset, including three CNN-based methods, two Transformer-based methods, and one GNN-based method, and conducted automated diagnostic experiments for malocclusion issues. The experimental results show that the OMNI dataset can facilitate the automated diagnosis research of malocclusion issues and provide a new benchmark for the research in this field. Our OMNI dataset and baseline code are publicly available at https://github.com/RoundFaceJ/OMNI.

Liyan Wang, Cong Wang, Jinshan Pan et al.

Ultra-High-Definition (UHD) image restoration has acquired remarkable attention due to its practical demand. In this paper, we construct UHD snow and rain benchmarks, named UHD-Snow and UHD-Rain, to remedy the deficiency in this field. The UHD-Snow/UHD-Rain is established by simulating the physics process of rain/snow into consideration and each benchmark contains 3200 degraded/clear image pairs of 4K resolution. Furthermore, we propose an effective UHD image restoration solution by considering gradient and normal priors in model design thanks to these priors' spatial and detail contributions. Specifically, our method contains two branches: (a) feature fusion and reconstruction branch in high-resolution space and (b) prior feature interaction branch in low-resolution space. The former learns high-resolution features and fuses prior-guided low-resolution features to reconstruct clear images, while the latter utilizes normal and gradient priors to mine useful spatial features and detail features to guide high-resolution recovery better. To better utilize these priors, we introduce single prior feature interaction and dual prior feature interaction, where the former respectively fuses normal and gradient priors with high-resolution features to enhance prior ones, while the latter calculates the similarity between enhanced prior ones and further exploits dual guided filtering to boost the feature interaction of dual priors. We conduct experiments on both new and existing public datasets and demonstrate the state-of-the-art performance of our method on UHD image low-light enhancement, dehazing, deblurring, desonwing, and deraining. The source codes and benchmarks are available at \url{https://github.com/wlydlut/UHDDIP}.

Fei Li, Chu Kiong Loo, Wei Shiung Liew et al.

In federated learning, data heterogeneity significantly impacts performance. A typical solution involves segregating these parameters into shared and personalized components, a concept also relevant in multi-task learning. Addressing this, we propose "Loop Improvement" (LI), a novel method enhancing this separation and feature extraction without necessitating a central server or data interchange among participants. Our experiments reveal LI's superiority in several aspects: In personalized federated learning environments, LI consistently outperforms the advanced FedALA algorithm in accuracy across diverse scenarios. Additionally, LI's feature extractor closely matches the performance achieved when aggregating data from all clients. In global model contexts, employing LI with stacked personalized layers and an additional network also yields comparable results to combined client data scenarios. Furthermore, LI's adaptability extends to multi-task learning, streamlining the extraction of common features across tasks and obviating the need for simultaneous training. This approach not only enhances individual task performance but also achieves accuracy levels on par with classic multi-task learning methods where all tasks are trained simultaneously. LI integrates a loop topology with layer-wise and end-to-end training, compatible with various neural network models. This paper also delves into the theoretical underpinnings of LI's effectiveness, offering insights into its potential applications. The code is on https://github.com/axedge1983/LI

Xiaofeng Liu, Jiaxin Gao, Xin Fan et al.

Contemporary Low-Light Image Enhancement (LLIE) techniques have made notable advancements in preserving image details and enhancing contrast, achieving commendable results on specific datasets. Nevertheless, these approaches encounter persistent challenges in efficiently mitigating dynamic noise and accommodating diverse low-light scenarios. Insufficient constraints on complex pixel-wise mapping learning lead to overfitting to specific types of noise and artifacts associated with low-light conditions, reducing effectiveness in variable lighting scenarios. To this end, we first propose a method for estimating the noise level in low light images in a quick and accurate way. This facilitates precise denoising, prevents over-smoothing, and adapts to dynamic noise patterns. Subsequently, we devise a Learnable Illumination Interpolator (LII), which employs learnlable interpolation operations between the input and unit vector to satisfy general constraints between illumination and input. Finally, we introduce a self-regularization loss that incorporates intrinsic image properties and essential visual attributes to guide the output towards meeting human visual expectations. Comprehensive experiments validate the competitiveness of our proposed algorithm in both qualitative and quantitative assessments. Notably, our noise estimation method, with linear time complexity and suitable for various denoisers, significantly improves both denoising and enhancement performance. Benefiting from this, our approach achieves a 0.675dB PSNR improvement on the LOL dataset and 0.818dB on the MIT dataset on LLIE task, even compared to supervised methods. The source code is available at \href{https://doi.org/10.5281/zenodo.11463142}{this DOI repository} and the specific code for noise estimation can be found at \href{https://github.com/GoogolplexGoodenough/noise_estimate}{this separate GitHub link}.

Yang Zou, Zhiding Yu, Xiaofeng Liu et al.

Recent advances in domain adaptation show that deep self-training presents a powerful means for unsupervised domain adaptation. These methods often involve an iterative process of predicting on target domain and then taking the confident predictions as pseudo-labels for retraining. However, since pseudo-labels can be noisy, self-training can put overconfident label belief on wrong classes, leading to deviated solutions with propagated errors. To address the problem, we propose a confidence regularized self-training (CRST) framework, formulated as regularized self-training. Our method treats pseudo-labels as continuous latent variables jointly optimized via alternating optimization. We propose two types of confidence regularization: label regularization (LR) and model regularization (MR). CRST-LR generates soft pseudo-labels while CRST-MR encourages the smoothness on network output. Extensive experiments on image classification and semantic segmentation show that CRSTs outperform their non-regularized counterpart with state-of-the-art performance. The code and models of this work are available at https://github.com/yzou2/CRST.

Xiaofeng Liu

Physics-informed neural networks (PINNs) are a simple surrogate-modelling paradigm for partial differential equations, but their standard strong-form residual formulation is ill suited to the shallow water equations (SWE). It cannot enforce local conservation, handle discontinuities, or leverage the boundary-conforming unstructured meshes used in real-world applications. We introduce ``Data-Guided FVM-PINN'', a framework that replaces the strong-form residual with a differentiable, well-balanced Roe Riemann-solver finite-volume (FVM) loss evaluated on unstructured meshes. The major finding is that physics-only FVM-PINN training often fails on realistic 2D problems: the network collapses to a trivial low-momentum state that nearly satisfies the FVM-PINN residual but bears no resemblance to the true flow. A loss-landscape diagnostic shows that the FVM-PINN loss at zero momentum is only about $7\times$ larger than at the trained solution, a shallow basin that an ordinary optimizer falls into; adding even sparse data turns this into a $310\times$ separation, breaking the degeneracy. On a 2D block-in-channel benchmark, just $200$ random velocity measurements drop the velocity-field $L_2$ error by $22\times$ versus physics-only; $50$ measurements still deliver a $7\times$ reduction. A controlled ablation isolates the contribution of the FVM-PINN loss: it reduces velocity-field $L_2$ by $\sim$$23\%$ in the sparse-data regime and is essentially neutral when dense reference data is available. On a real-world Savannah River reach ($1306$ cells, $3600$~s simulation, five Manning zones), the framework constructs an accurate surrogate from SRH-2D anchor data, with time-window decomposition reducing error monotonically via progressive initial-condition handoff.

Yubin Ge, Yongsong Huang, Xiaofeng Liu

Report-supervised (RSuper) learning seeks to alleviate the need for dense tumor voxel labels with constraints derived from radiology reports (e.g., volumes, counts, sizes, locations). In MRI studies of brain tumors, however, we often involve multi-parametric scans and substructures. Here, fine-grained modality/parameter-wise reports are usually provided along with global findings and are correlated with different substructures. Moreover, the reports often describe only the largest lesion and provide qualitative or uncertain cues (``mild,'' ``possible''). Classical RSuper losses (e.g., sum volume consistency) can over-constrain or hallucinate unreported findings under such incompleteness, and are unable to utilize these hierarchical findings or exploit the priors of varied lesion types in a merged dataset. We explicitly parse the global quantitative and modality-wise qualitative findings and introduce a unified, one-sided, uncertainty-aware formulation (MS-RSuper) that: (i) aligns modality-specific qualitative cues (e.g., T1c enhancement, FLAIR edema) with their corresponding substructures using existence and absence losses; (ii) enforces one-sided lower-bounds for partial quantitative cues (e.g., largest lesion size, minimal multiplicity); and (iii) adds extra- vs. intra-axial anatomical priors to respect cohort differences. Certainty tokens scale penalties; missing cues are down-weighted. On 1238 report-labeled BraTS-MET/MEN scans, our MS-RSuper largely outperforms both a sparsely-supervised baseline and a naive RSuper method.