Sihan Wang

IV
h-index42
22papers
165citations
Novelty47%
AI Score56

22 Papers

IRMay 27Code
Fine-Tuned LLM as a Complementary Predictor Improving Ads System

Hui Yang, Daiwei He, Kevin Jiang et al.

Recommendation systems power engagement and monetization across feeds, ads, and short-video platforms, but translating the latest advances in Large Language Models into Recommendation Systems (RecSys) gains remains rare, particularly in advertising and production-scale real-world industry setups. Prior real-world LLM successes typically fall into three buckets: (a) generative retrieval that directly predicts the next items for candidate generation, (b) late-stage re-ranking that uses LLMs, and (c) auxiliary signal enrichment with LLMs. We introduce a complementary paradigm for ads: a fine-tuned open-source LLM used not as a ranker, but as an ads-specific ancillary predictor, forecasting likely advertisers from user profiles and histories. This LLM-driven advertiser prediction augments conventional candidate generation and provides informative priors to downstream ranking. Developed in a large-scale production advertising system, our approach produces substantial offline improvements and measurable online business impact, demonstrating that LLM world knowledge and predictive capacity can be efficiently harnessed. Beyond validating LLMs for ads applications, our results show that targeted ancillary predictions can unlock end-to-end gains across both retrieval and late-stage ranking, offering a practical path to LLM-enhanced recommendation at scale.

MAJun 1
RadioMaster: Multi-Agent System for Autonomous Radio Signal Generation

Jiazhen Lei, Tianze Cao, Yuxin Sha et al.

Translating user intents into physical radio signals represents the critical yet notoriously tedious final step in wireless prototyping, as it requires intricate knowledge of physical layer details and presents immense implementation challenges. Large Language Models (LLMs) and multi-agent systems have revolutionized conventional software engineering, raising the compelling question of whether they can resolve these formidable difficulties. However, our investigations reveal that current models experience significant limitations and fail to accomplish this task when applied to radio signal generation. This performance degradation primarily stems from severe domain ignorance and a fundamental insensitivity to physical hardware constraints. To bridge this gap, we introduce RadioMaster, a fully autonomous multi-agent framework designed to seamlessly translate user input into real-world wireless emissions. RadioMaster operates on three synergistic pillars: RadioWiki for domain-specific knowledge retrieval, RadioAgent for collaborative I/Q sample generation alongside hardware configuration, and RadioEmulator for closed-loop physical layer verification. Furthermore, we construct RadioBench, the first comprehensive benchmark tailored specifically for the radio signal generation domain. Extensive real-world evaluations demonstrate that RadioMaster significantly outperforms state-of-the-art (SOTA) baselines regarding configuration viability and signal fidelity.

IVJun 10, 2022Code
Decoupling Predictions in Distributed Learning for Multi-Center Left Atrial MRI Segmentation

Zheyao Gao, Lei Li, Fuping Wu et al.

Distributed learning has shown great potential in medical image analysis. It allows to use multi-center training data with privacy protection. However, data distributions in local centers can vary from each other due to different imaging vendors, and annotation protocols. Such variation degrades the performance of learning-based methods. To mitigate the influence, two groups of methods have been proposed for different aims, i.e., the global methods and the personalized methods. The former are aimed to improve the performance of a single global model for all test data from unseen centers (known as generic data); while the latter target multiple models for each center (denoted as local data). However, little has been researched to achieve both goals simultaneously. In this work, we propose a new framework of distributed learning that bridges the gap between two groups, and improves the performance for both generic and local data. Specifically, our method decouples the predictions for generic data and local data, via distribution-conditioned adaptation matrices. Results on multi-center left atrial (LA) MRI segmentation showed that our method demonstrated superior performance over existing methods on both generic and local data. Our code is available at https://github.com/key1589745/decouple_predict

IVNov 6, 2022
MyoPS-Net: Myocardial Pathology Segmentation with Flexible Combination of Multi-Sequence CMR Images

Junyi Qiu, Lei Li, Sihan Wang et al.

Myocardial pathology segmentation (MyoPS) can be a prerequisite for the accurate diagnosis and treatment planning of myocardial infarction. However, achieving this segmentation is challenging, mainly due to the inadequate and indistinct information from an image. In this work, we develop an end-to-end deep neural network, referred to as MyoPS-Net, to flexibly combine five-sequence cardiac magnetic resonance (CMR) images for MyoPS. To extract precise and adequate information, we design an effective yet flexible architecture to extract and fuse cross-modal features. This architecture can tackle different numbers of CMR images and complex combinations of modalities, with output branches targeting specific pathologies. To impose anatomical knowledge on the segmentation results, we first propose a module to regularize myocardium consistency and localize the pathologies, and then introduce an inclusiveness loss to utilize relations between myocardial scars and edema. We evaluated the proposed MyoPS-Net on two datasets, i.e., a private one consisting of 50 paired multi-sequence CMR images and a public one from MICCAI2020 MyoPS Challenge. Experimental results showed that MyoPS-Net could achieve state-of-the-art performance in various scenarios. Note that in practical clinics, the subjects may not have full sequences, such as missing LGE CMR or mapping CMR scans. We therefore conducted extensive experiments to investigate the performance of the proposed method in dealing with such complex combinations of different CMR sequences. Results proved the superiority and generalizability of MyoPS-Net, and more importantly, indicated a practical clinical application.

IVFeb 7, 2023
Aligning Multi-Sequence CMR Towards Fully Automated Myocardial Pathology Segmentation

Wangbin Ding, Lei Li, Junyi Qiu et al.

Myocardial pathology segmentation (MyoPS) is critical for the risk stratification and treatment planning of myocardial infarction (MI). Multi-sequence cardiac magnetic resonance (MS-CMR) images can provide valuable information. For instance, balanced steady-state free precession cine sequences present clear anatomical boundaries, while late gadolinium enhancement and T2-weighted CMR sequences visualize myocardial scar and edema of MI, respectively. Existing methods usually fuse anatomical and pathological information from different CMR sequences for MyoPS, but assume that these images have been spatially aligned. However, MS-CMR images are usually unaligned due to the respiratory motions in clinical practices, which poses additional challenges for MyoPS. This work presents an automatic MyoPS framework for unaligned MS-CMR images. Specifically, we design a combined computing model for simultaneous image registration and information fusion, which aggregates multi-sequence features into a common space to extract anatomical structures (i.e., myocardium). Consequently, we can highlight the informative regions in the common space via the extracted myocardium to improve MyoPS performance, considering the spatial relationship between myocardial pathologies and myocardium. Experiments on a private MS-CMR dataset and a public dataset from the MYOPS2020 challenge show that our framework could achieve promising performance for fully automatic MyoPS.

IVJan 15, 2023
Unsupervised Cardiac Segmentation Utilizing Synthesized Images from Anatomical Labels

Sihan Wang, Fuping Wu, Lei Li et al.

Cardiac segmentation is in great demand for clinical practice. Due to the enormous labor of manual delineation, unsupervised segmentation is desired. The ill-posed optimization problem of this task is inherently challenging, requiring well-designed constraints. In this work, we propose an unsupervised framework for multi-class segmentation with both intensity and shape constraints. Firstly, we extend a conventional non-convex energy function as an intensity constraint and implement it with U-Net. For shape constraint, synthetic images are generated from anatomical labels via image-to-image translation, as shape supervision for the segmentation network. Moreover, augmentation invariance is applied to facilitate the segmentation network to learn the latent features in terms of shape. We evaluated the proposed framework using the public datasets from MICCAI2019 MSCMR Challenge and achieved promising results on cardiac MRIs with Dice scores of 0.5737, 0.7796, and 0.6287 in Myo, LV, and RV, respectively.

LGMay 17
FishBack: Pullback Fisher Geometry for Optimal Activation Steering in Transformers

Sihan Wang, Jiayi Zhao

Activation steering methods modify intermediate representations of language models to control output behavior, but universally assume the activation space is Euclidean. We show this assumption fails drastically: the local geometry induced by the model's own output behavior -- the Fisher information metric of the softmax layer, pulled back through the Jacobian of subsequent layers -- deviates from the Euclidean metric by over 97% in relative spectral norm on GPT-2, with an effective dimensionality of only 2--17% of the ambient space. From this pullback Fisher metric, we derive a closed-form steering equation that identifies the minimum-distortion direction for any target concept, yielding a closed-form optimal direction at each point that can be applied iteratively without manifold fitting or data-driven geometry estimation. We call the resulting framework FishBack. The metric admits a layer-wise recursive decomposition, which reveals that existing methods -- CAA, ActAdd, ITI, and others -- each implicitly adopt a particular approximate metric, and that their performance gaps are quantitatively predicted by a single spectral diagnostic: the ratio of their implicit metric's cost to the Fisher-optimal cost. On GPT-2, iterative pullback steering consistently outperforms all Euclidean baselines across three verb-morphology concepts and four layers, with off-target KL reductions of $1.3\times$--$2.5\times$ relative to Euclidean gradient ascent and $1.5\times$ relative to CAA at matched concept probability.

CLApr 28Code
DV-World: Benchmarking Data Visualization Agents in Real-World Scenarios

Jinxiang Meng, Shaoping Huang, Fangyu Lei et al.

Real-world data visualization (DV) requires native environmental grounding, cross-platform evolution, and proactive intent alignment. Yet, existing benchmarks often suffer from code-sandbox confinement, single-language creation-only tasks, and assumption of perfect intent. To bridge these gaps, we introduce DV-World, a benchmark of 260 tasks designed to evaluate DV agents across real-world professional lifecycles. DV-World spans three domains: DV-Sheet for native spreadsheet manipulation including chart and dashboard creation as well as diagnostic repair; DV-Evolution for adapting and restructuring reference visual artifacts to fit new data across diverse programming paradigms and DV-Interact for proactive intent alignment with a user simulator that mimics real-world ambiguous requirements. Our hybrid evaluation framework integrates Table-value Alignment for numerical precision and MLLM-as-a-Judge with rubrics for semantic-visual assessment. Experiments reveal that state-of-the-art models achieve less than 50% overall performance, exposing critical deficits in handling the complex challenges of real-world data visualization. DV-World provides a realistic testbed to steer development toward the versatile expertise required in enterprise workflows. Our data and code are available at \href{https://github.com/DA-Open/DV-World}{this project page}.

CVMay 20, 2025Code
Learning Concept-Driven Logical Rules for Interpretable and Generalizable Medical Image Classification

Yibo Gao, Hangqi Zhou, Zheyao Gao et al.

The pursuit of decision safety in clinical applications highlights the potential of concept-based methods in medical imaging. While these models offer active interpretability, they often suffer from concept leakages, where unintended information within soft concept representations undermines both interpretability and generalizability. Moreover, most concept-based models focus solely on local explanations (instance-level), neglecting the global decision logic (dataset-level). To address these limitations, we propose Concept Rule Learner (CRL), a novel framework to learn Boolean logical rules from binarized visual concepts. CRL employs logical layers to capture concept correlations and extract clinically meaningful rules, thereby providing both local and global interpretability. Experiments on two medical image classification tasks show that CRL achieves competitive performance with existing methods while significantly improving generalizability to out-of-distribution data. The code of our work is available at https://github.com/obiyoag/crl.

DSMay 7
Discrete Optimal Transport: Rapid Convergence of Simulated Annealing Algorithms

Yuchen He, Tianhui Jiang, Sihan Wang et al.

We develop a discrete optimal transport framework for analyzing simulated annealing algorithms on finite state spaces. Building on the discrete Wasserstein metric introduced by Maas (J. Funct. Anal., 2011), we define a generalized discrete Wasserstein-2 distance and the associated notion of \emph{discrete action} for paths of probability measures on graphs. Using these tools, we establish non-asymptotic convergence guarantees for simulated annealing: the KL divergence between the algorithm's output and the target distribution is controlled by the discrete action of the annealing path. This can be viewed as the discrete counterpart of the action-based analysis of annealed Langevin dynamics in continuous spaces by Guo, Tao, and Chen (ICLR 2025). As applications, we analyze simulated annealing for two fundamental models in statistical physics. For the \emph{mean-field Ising model}, we show that annealed single-site Glauber dynamics achieves $\varepsilon$ error in KL divergence in $O(n^5β^2/\varepsilon)$ steps at \emph{any} inverse temperature $β\ge 0$. For the \emph{mean-field $q$-state Potts model}, we show that annealed $(q-1)$-block Glauber dynamics achieves $\varepsilon$ error in $\mathrm{poly}(n, β, 1/\varepsilon)$ steps for all $β\ge β_{\mathsf{s}}=q/2$, the regime where the disordered phase has completely lost stability. In both cases, the key technical contribution is a polynomial upper bound on the discrete action, obtained by exploiting the symmetry of the model to reduce the analysis to a low-dimensional projected chain.

AISep 29, 2025Code
Evaluating Foundation Models with Pathological Concept Learning for Kidney Cancer

Shangqi Gao, Sihan Wang, Yibo Gao et al.

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological concepts for kidney cancer. Then, we extract deep features from whole slide images using foundation models, construct pathological graphs to capture spatial correlations, and trained graph neural networks to identify these concepts. Finally, we demonstrate the effectiveness of this approach in kidney cancer survival analysis, highlighting its explainability and fairness in identifying low- and high-risk patients. The source code has been released by https://github.com/shangqigao/RadioPath.

CLJul 21, 2025
Interaction as Intelligence: Deep Research With Human-AI Partnership

Lyumanshan Ye, Xiaojie Cai, Xinkai Wang et al.

This paper introduces "Interaction as Intelligence" research series, presenting a reconceptualization of human-AI relationships in deep research tasks. Traditional approaches treat interaction merely as an interface for accessing AI capabilities-a conduit between human intent and machine output. We propose that interaction itself constitutes a fundamental dimension of intelligence. As AI systems engage in extended thinking processes for research tasks, meaningful interaction transitions from an optional enhancement to an essential component of effective intelligence. Current deep research systems adopt an "input-wait-output" paradigm where users initiate queries and receive results after black-box processing. This approach leads to error cascade effects, inflexible research boundaries that prevent question refinement during investigation, and missed opportunities for expertise integration. To address these limitations, we introduce Deep Cognition, a system that transforms the human role from giving instructions to cognitive oversight-a mode of engagement where humans guide AI thinking processes through strategic intervention at critical junctures. Deep cognition implements three key innovations: (1)Transparent, controllable, and interruptible interaction that reveals AI reasoning and enables intervention at any point; (2)Fine-grained bidirectional dialogue; and (3)Shared cognitive context where the system observes and adapts to user behaviors without explicit instruction. User evaluation demonstrates that this cognitive oversight paradigm outperforms the strongest baseline across six key metrics: Transparency(+20.0%), Fine-Grained Interaction(+29.2%), Real-Time Intervention(+18.5%), Ease of Collaboration(+27.7%), Results-Worth-Effort(+8.8%), and Interruptibility(+20.7%). Evaluations on challenging research problems show 31.8% to 50.0% points of improvements over deep research systems.

AIMar 19, 2025
Empowering Medical Multi-Agents with Clinical Consultation Flow for Dynamic Diagnosis

Sihan Wang, Suiyang Jiang, Yibo Gao et al.

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis combining multi-modal information. While these models excel in static tasks, they struggle with dynamic diagnosis, failing to manage multi-turn interactions and often making premature diagnostic decisions due to insufficient persistence in information collection.To address this, we propose a multi-agent framework inspired by consultation flow and reinforcement learning (RL) to simulate the entire consultation process, integrating multiple clinical information for effective diagnosis. Our approach incorporates a hierarchical action set, structured from clinic consultation flow and medical textbook, to effectively guide the decision-making process. This strategy improves agent interactions, enabling them to adapt and optimize actions based on the dynamic state. We evaluated our framework on a public dynamic diagnosis benchmark. The proposed framework evidentially improves the baseline methods and achieves state-of-the-art performance compared to existing foundation model-based methods.

IRSep 4, 2025
Decoupled Entity Representation Learning for Pinterest Ads Ranking

Jie Liu, Yinrui Li, Jiankai Sun et al.

In this paper, we introduce a novel framework following an upstream-downstream paradigm to construct user and item (Pin) embeddings from diverse data sources, which are essential for Pinterest to deliver personalized Pins and ads effectively. Our upstream models are trained on extensive data sources featuring varied signals, utilizing complex architectures to capture intricate relationships between users and Pins on Pinterest. To ensure scalability of the upstream models, entity embeddings are learned, and regularly refreshed, rather than real-time computation, allowing for asynchronous interaction between the upstream and downstream models. These embeddings are then integrated as input features in numerous downstream tasks, including ad retrieval and ranking models for CTR and CVR predictions. We demonstrate that our framework achieves notable performance improvements in both offline and online settings across various downstream tasks. This framework has been deployed in Pinterest's production ad ranking systems, resulting in significant gains in online metrics.

CVAug 11, 2025
Decoupled Functional Evaluation of Autonomous Driving Models via Feature Map Quality Scoring

Ludan Zhang, Sihan Wang, Yuqi Dai et al.

End-to-end models are emerging as the mainstream in autonomous driving perception and planning. However, the lack of explicit supervision signals for intermediate functional modules leads to opaque operational mechanisms and limited interpretability, making it challenging for traditional methods to independently evaluate and train these modules. Pioneering in the issue, this study builds upon the feature map-truth representation similarity-based evaluation framework and proposes an independent evaluation method based on Feature Map Convergence Score (FMCS). A Dual-Granularity Dynamic Weighted Scoring System (DG-DWSS) is constructed, formulating a unified quantitative metric - Feature Map Quality Score - to enable comprehensive evaluation of the quality of feature maps generated by functional modules. A CLIP-based Feature Map Quality Evaluation Network (CLIP-FMQE-Net) is further developed, combining feature-truth encoders and quality score prediction heads to enable real-time quality analysis of feature maps generated by functional modules. Experimental results on the NuScenes dataset demonstrate that integrating our evaluation module into the training improves 3D object detection performance, achieving a 3.89 percent gain in NDS. These results verify the effectiveness of our method in enhancing feature representation quality and overall model performance.

IRAug 7, 2025
Multi-Faceted Large Embedding Tables for Pinterest Ads Ranking

Runze Su, Jiayin Jin, Jiacheng Li et al.

Large embedding tables are indispensable in modern recommendation systems, thanks to their ability to effectively capture and memorize intricate details of interactions among diverse entities. As we explore integrating large embedding tables into Pinterest's ads ranking models, we encountered not only common challenges such as sparsity and scalability, but also several obstacles unique to our context. Notably, our initial attempts to train large embedding tables from scratch resulted in neutral metrics. To tackle this, we introduced a novel multi-faceted pretraining scheme that incorporates multiple pretraining algorithms. This approach greatly enriched the embedding tables and resulted in significant performance improvements. As a result, the multi-faceted large embedding tables bring great performance gain on both the Click-Through Rate (CTR) and Conversion Rate (CVR) domains. Moreover, we designed a CPU-GPU hybrid serving infrastructure to overcome GPU memory limits and elevate the scalability. This framework has been deployed in the Pinterest Ads system and achieved 1.34% online CPC reduction and 2.60% CTR increase with neutral end-to-end latency change.

IVJul 3, 2025
CineMyoPS: Segmenting Myocardial Pathologies from Cine Cardiac MR

Wangbin Ding, Lei Li, Junyi Qiu et al.

Myocardial infarction (MI) is a leading cause of death worldwide. Late gadolinium enhancement (LGE) and T2-weighted cardiac magnetic resonance (CMR) imaging can respectively identify scarring and edema areas, both of which are essential for MI risk stratification and prognosis assessment. Although combining complementary information from multi-sequence CMR is useful, acquiring these sequences can be time-consuming and prohibitive, e.g., due to the administration of contrast agents. Cine CMR is a rapid and contrast-free imaging technique that can visualize both motion and structural abnormalities of the myocardium induced by acute MI. Therefore, we present a new end-to-end deep neural network, referred to as CineMyoPS, to segment myocardial pathologies, \ie scars and edema, solely from cine CMR images. Specifically, CineMyoPS extracts both motion and anatomy features associated with MI. Given the interdependence between these features, we design a consistency loss (resembling the co-training strategy) to facilitate their joint learning. Furthermore, we propose a time-series aggregation strategy to integrate MI-related features across the cardiac cycle, thereby enhancing segmentation accuracy for myocardial pathologies. Experimental results on a multi-center dataset demonstrate that CineMyoPS achieves promising performance in myocardial pathology segmentation, motion estimation, and anatomy segmentation.

CVJan 2, 2025
InDeed: Interpretable image deep decomposition with guaranteed generalizability

Sihan Wang, Shangqi Gao, Fuping Wu et al.

Image decomposition aims to analyze an image into elementary components, which is essential for numerous downstream tasks and also by nature provides certain interpretability to the analysis. Deep learning can be powerful for such tasks, but surprisingly their combination with a focus on interpretability and generalizability is rarely explored. In this work, we introduce a novel framework for interpretable deep image decomposition, combining hierarchical Bayesian modeling and deep learning to create an architecture-modularized and model-generalizable deep neural network (DNN). The proposed framework includes three steps: (1) hierarchical Bayesian modeling of image decomposition, (2) transforming the inference problem into optimization tasks, and (3) deep inference via a modularized Bayesian DNN. We further establish a theoretical connection between the loss function and the generalization error bound, which inspires a new test-time adaptation approach for out-of-distribution scenarios. We instantiated the application using two downstream tasks, \textit{i.e.}, image denoising, and unsupervised anomaly detection, and the results demonstrated improved generalizability as well as interpretability of our methods. The source code will be released upon the acceptance of this paper.

IVJan 10, 2022
MyoPS: A Benchmark of Myocardial Pathology Segmentation Combining Three-Sequence Cardiac Magnetic Resonance Images

Lei Li, Fuping Wu, Sihan Wang et al.

Assessment of myocardial viability is essential in diagnosis and treatment management of patients suffering from myocardial infarction, and classification of pathology on myocardium is the key to this assessment. This work defines a new task of medical image analysis, i.e., to perform myocardial pathology segmentation (MyoPS) combining three-sequence cardiac magnetic resonance (CMR) images, which was first proposed in the MyoPS challenge, in conjunction with MICCAI 2020. The challenge provided 45 paired and pre-aligned CMR images, allowing algorithms to combine the complementary information from the three CMR sequences for pathology segmentation. In this article, we provide details of the challenge, survey the works from fifteen participants and interpret their methods according to five aspects, i.e., preprocessing, data augmentation, learning strategy, model architecture and post-processing. In addition, we analyze the results with respect to different factors, in order to examine the key obstacles and explore potential of solutions, as well as to provide a benchmark for future research. We conclude that while promising results have been reported, the research is still in the early stage, and more in-depth exploration is needed before a successful application to the clinics. Note that MyoPS data and evaluation tool continue to be publicly available upon registration via its homepage (www.sdspeople.fudan.edu.cn/zhuangxiahai/0/myops20/).

ROOct 4, 2021
Design and Characterization of a 3D-printed Pneumatically-driven Bistable Valve with Tunable Characteristics

Sihan Wang, Liang He, Perla Maiolino

Although research studies in pneumatic soft robots develop rapidly, most pneumatic actuators are still controlled by rigid valves and conventional electronics. The existence of these rigid, electronic components sacrifices the compliance and adaptability of soft robots.} Current electronics-free valve designs based on soft materials are facing challenges in behaviour consistency, design flexibility, and fabrication complexity. Taking advantages of soft material 3D printing, this paper presents a new design of a bi-stable pneumatic valve, which utilises two soft, pneumatically-driven, and symmetrically-oriented conical shells with structural bistability to stabilise and regulate the airflow. The critical pressure required to operate the valve can be adjusted by changing the design features of the soft bi-stable structure. Multi-material printing simplifies the valve fabrication, enhances the flexibility in design feature optimisations, and improves the system repeatability. In this work, both a theoretical model and physical experiments are introduced to examine the relationships between the critical operating pressure and the key design features. Results with valve characteristic tuning via material stiffness changing show better effectiveness compared to the change of geometry design features (demonstrated largest tunable critical pressure range from 15.3 to 65.2 kPa and fastest response time $\leq$ 1.8 s.

IVNov 17, 2020
Anatomy Prior Based U-net for Pathology Segmentation with Attention

Yuncheng Zhou, Ke Zhang, Xinzhe Luo et al.

Pathological area segmentation in cardiac magnetic resonance (MR) images plays a vital role in the clinical diagnosis of cardiovascular diseases. Because of the irregular shape and small area, pathological segmentation has always been a challenging task. We propose an anatomy prior based framework, which combines the U-net segmentation network with the attention technique. Leveraging the fact that the pathology is inclusive, we propose a neighborhood penalty strategy to gauge the inclusion relationship between the myocardium and the myocardial infarction and no-reflow areas. This neighborhood penalty strategy can be applied to any two labels with inclusive relationships (such as the whole infarction and myocardium, etc.) to form a neighboring loss. The proposed framework is evaluated on the EMIDEC dataset. Results show that our framework is effective in pathological area segmentation.

IVAug 13, 2020
Multi-Modality Pathology Segmentation Framework: Application to Cardiac Magnetic Resonance Images

Zhen Zhang, Chenyu Liu, Wangbin Ding et al.

Multi-sequence of cardiac magnetic resonance (CMR) images can provide complementary information for myocardial pathology (scar and edema). However, it is still challenging to fuse these underlying information for pathology segmentation effectively. This work presents an automatic cascade pathology segmentation framework based on multi-modality CMR images. It mainly consists of two neural networks: an anatomical structure segmentation network (ASSN) and a pathological region segmentation network (PRSN). Specifically, the ASSN aims to segment the anatomical structure where the pathology may exist, and it can provide a spatial prior for the pathological region segmentation. In addition, we integrate a denoising auto-encoder (DAE) into the ASSN to generate segmentation results with plausible shapes. The PRSN is designed to segment pathological region based on the result of ASSN, in which a fusion block based on channel attention is proposed to better aggregate multi-modality information from multi-modality CMR images. Experiments from the MyoPS2020 challenge dataset show that our framework can achieve promising performance for myocardial scar and edema segmentation.