Suvrankar Datta

Hong-Yu Zhou, Julián Nicolás Acosta, Subathra Adithan et al.

Current medical AI systems are often limited to narrow applications, hindering widespread adoption. We present MedVersa, a generalist foundation model trained on tens of millions of compiled medical instances. MedVersa unlocks generalist learning from multimodal inputs and outputs, representing the first example of a generalist model reaching competitive performance with leading specialized solutions across a variety of medical imaging scenarios. MedVersa achieves state-of-the-art performance in nine tasks, sometimes outperforming counterparts by over 10%. Radiologist evaluation shows MedVersa-generated reports get superior performance in 95% of normal studies, while matching or exceeding human reports in 71% of cases overall. User studies showed notable reductions in report writing time and discrepancies with the use of MedVersa. Our findings underscore the value of flexible, multimodal AI systems in advancing medical image interpretation and supporting clinical expertise.

Suvrankar Datta, Divya Buchireddygari, Lakshmi Vennela Chowdary Kaza et al.

Generalist multimodal AI systems such as large language models (LLMs) and vision language models (VLMs) are increasingly accessed by clinicians and patients alike for medical image interpretation through widely available consumer-facing chatbots. Most evaluations claiming expert level performance are on public datasets containing common pathologies. Rigorous evaluation of frontier models on difficult diagnostic cases remains limited. We developed a pilot benchmark of 50 expert-level "spot diagnosis" cases across multiple imaging modalities to evaluate the performance of frontier AI models against board-certified radiologists and radiology trainees. To mirror real-world usage, the reasoning modes of five popular frontier AI models were tested through their native web interfaces, viz. OpenAI o3, OpenAI GPT-5, Gemini 2.5 Pro, Grok-4, and Claude Opus 4.1. Accuracy was scored by blinded experts, and reproducibility was assessed across three independent runs. GPT-5 was additionally evaluated across various reasoning modes. Reasoning quality errors were assessed and a taxonomy of visual reasoning errors was defined. Board-certified radiologists achieved the highest diagnostic accuracy (83%), outperforming trainees (45%) and all AI models (best performance shown by GPT-5: 30%). Reliability was substantial for GPT-5 and o3, moderate for Gemini 2.5 Pro and Grok-4, and poor for Claude Opus 4.1. These findings demonstrate that advanced frontier models fall far short of radiologists in challenging diagnostic cases. Our benchmark highlights the present limitations of generalist AI in medical imaging and cautions against unsupervised clinical use. We also provide a qualitative analysis of reasoning traces and propose a practical taxonomy of visual reasoning errors by AI models for better understanding their failure modes, informing evaluation standards and guiding more robust model development.

Shripad Pate, Aiman Farooq, Suvrankar Datta et al.

Accurate rib fracture identification and classification are essential for treatment planning. However, existing datasets often lack fine-grained annotations, particularly regarding rib fracture characterization, type, and precise anatomical location on individual ribs. To address this, we introduce a novel rib fracture annotation protocol tailored for fracture classification. Further, we enhance fracture classification by leveraging cross-modal embeddings that bridge radiological images and clinical descriptions. Our approach employs hyperbolic embeddings to capture the hierarchical nature of fracture, mapping visual features and textual descriptions into a shared non-Euclidean manifold. This framework enables more nuanced similarity computations between imaging characteristics and clinical descriptions, accounting for the inherent hierarchical relationships in fracture taxonomy. Experimental results demonstrate that our approach outperforms existing methods across multiple classification tasks, with average recall improvements of 6% on the AirRib dataset and 17.5% on the public RibFrac dataset.