Yu Fu

Yu Fu, Yanyan Huang, Yalin Wang et al.

Chronological age of healthy brain is able to be predicted using deep neural networks from T1-weighted magnetic resonance images (T1 MRIs), and the predicted brain age could serve as an effective biomarker for detecting aging-related diseases or disorders. In this paper, we propose an end-to-end neural network architecture, referred to as optimal transport based feature pyramid fusion (OTFPF) network, for the brain age estimation with T1 MRIs. The OTFPF consists of three types of modules: Optimal Transport based Feature Pyramid Fusion (OTFPF) module, 3D overlapped ConvNeXt (3D OL-ConvNeXt) module and fusion module. These modules strengthen the OTFPF network's understanding of each brain's semi-multimodal and multi-level feature pyramid information, and significantly improve its estimation performances. Comparing with recent state-of-the-art models, the proposed OTFPF converges faster and performs better. The experiments with 11,728 MRIs aged 3-97 years show that OTFPF network could provide accurate brain age estimation, yielding mean absolute error (MAE) of 2.097, Pearson's correlation coefficient (PCC) of 0.993 and Spearman's rank correlation coefficient (SRCC) of 0.989, between the estimated and chronological ages. Widespread quantitative experiments and ablation experiments demonstrate the superiority and rationality of OTFPF network. The codes and implement details will be released on GitHub: https://github.com/ZJU-Brain/OTFPF after final decision.

Yu Fu, Deyi Xiong, Yue Dong · mila

To mitigate potential risks associated with language models, recent AI detection research proposes incorporating watermarks into machine-generated text through random vocabulary restrictions and utilizing this information for detection. While these watermarks only induce a slight deterioration in perplexity, our empirical investigation reveals a significant detriment to the performance of conditional text generation. To address this issue, we introduce a simple yet effective semantic-aware watermarking algorithm that considers the characteristics of conditional text generation and the input context. Experimental results demonstrate that our proposed method yields substantial improvements across various text generation models, including BART and Flan-T5, in tasks such as summarization and data-to-text generation while maintaining detection ability.

Yu Fu, Deyi Xiong, Yue Dong · mila

We introduce inverse reinforcement learning (IRL) as an effective paradigm for training abstractive summarization models, imitating human summarization behaviors. Our IRL model estimates the reward function using a suite of important sub-rewards for summarization and concurrently optimizes the policy network. Experimental results across datasets in different domains (CNN/DailyMail and WikiHow) and various model sizes (BART-base and BART-large) demonstrate the superiority of our proposed IRL model for summarization over MLE and RL baselines. The resulting summaries exhibit greater similarity to human-crafted gold references, outperforming MLE and RL baselines on metrics such as ROUGE, coverage, novelty, compression ratio, factuality, and human evaluations.

Huanli Gong, Zhipeng Wei, Yu Fu et al.

Multi-turn jailbreak attacks pose a growing threat to large language model (LLM) safety because they exploit feedback from auxiliary judge models to iteratively refine prompts toward harmful goals. Existing defenses largely detect or block unsafe content at individual turns or at the final response, leaving the judge-driven refinement loop intact and allowing attackers to extract informative feedback from intermediate interactions. We introduce D-Judge, a semantics-preserving output rewriting defense that intervenes directly in this loop by rewriting the victim LLM's responses before they are evaluated by the attacker's judge. By misaligning the judge's feedback signal without changing the meaning of the original response, D-Judge derails the attacker's prompt-refinement process, causing subsequent queries to be optimized against a distorted signal of attack progress. To improve D-Judge's ability to produce such rewrites, we construct a dataset of semantically equivalent response pairs that induce different judge-assigned harmfulness scores, and use it for supervised fine-tuning followed by direct preference optimization. Experiments on HarmBench show that D-Judge reduces the success rate of state-of-the-art multi-turn jailbreaks while preserving performance on benign benchmarks.

Longxuan Yu, Shaorong Zhang, Yu Fu et al.

Masked diffusion language models (MDLMs) re-predict every position at each denoising step, but standard samplers commit tokens once revealed, leaving this revision capability unused. Existing approaches either add heuristic or learned mechanisms to revise committed tokens, or remask them back to [MASK] before re-predicting; a principled sampler that directly revises visible tokens without auxiliary modules remains underexplored. We introduce D3IM, a parameter-free sampler derived as a corrector-style reverse update that permits direct visible-to-visible revision without additional modules or auxiliary passes. D3IM also reveals a model-side obstacle we term preservation bias: the model tends to reproduce its own wrong committed tokens rather than correct them. We address this with SCOPE (Self-Conditioned On Prediction Errors), a lightweight post-training procedure that simulates D3IM's sampling process. On LLaDA-8B at 64 denoising steps, SCOPE+D3IM improves over the original LLaDA-8B with standard unmasking by +13.0 on GSM8K (68.3%), +4.8 on MATH-500 (23.6%), +15.3 on HumanEval (29.3%), and +10.4 on MBPP (30.8%), with gains that increase as more denoising steps are used on math and HumanEval.

Yanyan Huang, Weiqin Zhao, Shujun Wang et al.

Whole slide image (WSI) analysis has become increasingly important in the medical imaging community, enabling automated and objective diagnosis, prognosis, and therapeutic-response prediction. However, in clinical practice, the ever-evolving environment hamper the utility of WSI analysis models. In this paper, we propose the FIRST continual learning framework for WSI analysis, named ConSlide, to tackle the challenges of enormous image size, utilization of hierarchical structure, and catastrophic forgetting by progressive model updating on multiple sequential datasets. Our framework contains three key components. The Hierarchical Interaction Transformer (HIT) is proposed to model and utilize the hierarchical structural knowledge of WSI. The Breakup-Reorganize (BuRo) rehearsal method is developed for WSI data replay with efficient region storing buffer and WSI reorganizing operation. The asynchronous updating mechanism is devised to encourage the network to learn generic and specific knowledge respectively during the replay stage, based on a nested cross-scale similarity learning (CSSL) module. We evaluated the proposed ConSlide on four public WSI datasets from TCGA projects. It performs best over other state-of-the-art methods with a fair WSI-based continual learning setting and achieves a better trade-off of the overall performance and forgetting on previous task

Longxuan Yu, Yunshu Wu, Yu Fu et al.

Discrete Masked diffusion language models generate text by iterative parallel decoding, but few-step decoding suffers from a tradeoff between length and quality: with a fixed step budget, standard methods can generate a short, high-quality output, or they can produce long but repetitive text. Continuous denoising can sidestep this tradeoff by evolving all positions jointly in embedding space, but building such a model from scratch at scale remains an open problem. We show that a pretrained masked DLM can instead be lightly adapted to support continuous embedding-space denoising. Starting from LLaDA-8B-Instruct, we continue-pretrain for only 1,000 steps with Discrete Stochastic Localization (DSL), replacing binary masking with continuous per-token Gaussian noise as a soft mask. The adapted model supports continuous inference that evolves all positions jointly in embedding space and defers hard token commitment to the final step. On zero-shot summarization at low step budgets (<=16 forward passes), DSL-LLaDA-SDE achieves the best ROUGE-1 on all four benchmarks and largely avoids the premature-termination / repetition tradeoff of iterative unmasking. The same adaptation also yields selective noisy-state robustness: the model corrects corrupted tokens while preserving clean ones. Control experiments using standard masked diffusion training with the same compute demonstrate neither behavior.

Erfan Shayegani, Md Abdullah Al Mamun, Yu Fu et al.

Large Language Models (LLMs) are swiftly advancing in architecture and capability, and as they integrate more deeply into complex systems, the urgency to scrutinize their security properties grows. This paper surveys research in the emerging interdisciplinary field of adversarial attacks on LLMs, a subfield of trustworthy ML, combining the perspectives of Natural Language Processing and Security. Prior work has shown that even safety-aligned LLMs (via instruction tuning and reinforcement learning through human feedback) can be susceptible to adversarial attacks, which exploit weaknesses and mislead AI systems, as evidenced by the prevalence of `jailbreak' attacks on models like ChatGPT and Bard. In this survey, we first provide an overview of large language models, describe their safety alignment, and categorize existing research based on various learning structures: textual-only attacks, multi-modal attacks, and additional attack methods specifically targeting complex systems, such as federated learning or multi-agent systems. We also offer comprehensive remarks on works that focus on the fundamental sources of vulnerabilities and potential defenses. To make this field more accessible to newcomers, we present a systematic review of existing works, a structured typology of adversarial attack concepts, and additional resources, including slides for presentations on related topics at the 62nd Annual Meeting of the Association for Computational Linguistics (ACL'24).

Rui Hua, Yu Wei, Zixin Shu et al.

Large language models (LLMs) are advancing rapidly in medical NLP, yet Traditional Chinese Medicine (TCM) with its distinctive ontology, terminology, and reasoning patterns requires domain-faithful evaluation. Existing TCM benchmarks are fragmented in coverage and scale and rely on non-unified or generation-heavy scoring that hinders fair comparison. We present the LingLanMiDian (LingLan) benchmark, a large-scale, expert-curated, multi-task suite that unifies evaluation across knowledge recall, multi-hop reasoning, information extraction, and real-world clinical decision-making. LingLan introduces a consistent metric design, a synonym-tolerant protocol for clinical labels, a per-dataset 400-item Hard subset, and a reframing of diagnosis and treatment recommendation into single-choice decision recognition. We conduct comprehensive, zero-shot evaluations on 14 leading open-source and proprietary LLMs, providing a unified perspective on their strengths and limitations in TCM commonsense knowledge understanding, reasoning, and clinical decision support; critically, the evaluation on Hard subset reveals a substantial gap between current models and human experts in TCM-specialized reasoning. By bridging fundamental knowledge and applied reasoning through standardized evaluation, LingLan establishes a unified, quantitative, and extensible foundation for advancing TCM LLMs and domain-specific medical AI research. All evaluation data and code are available at https://github.com/TCMAI-BJTU/LingLan and http://tcmnlp.com.

Haitao Tang, Yu Fu, Lei Sun et al.

Transducer is one of the mainstream frameworks for streaming speech recognition. There is a performance gap between the streaming and non-streaming transducer models due to limited context. To reduce this gap, an effective way is to ensure that their hidden and output distributions are consistent, which can be achieved by hierarchical knowledge distillation. However, it is difficult to ensure the distribution consistency simultaneously because the learning of the output distribution depends on the hidden one. In this paper, we propose an adaptive two-stage knowledge distillation method consisting of hidden layer learning and output layer learning. In the former stage, we learn hidden representation with full context by applying mean square error loss function. In the latter stage, we design a power transformation based adaptive smoothness method to learn stable output distribution. It achieved 19\% relative reduction in word error rate, and a faster response for the first token compared with the original streaming model in LibriSpeech corpus.

Xuming Hu, Zhijiang Guo, Yu Fu et al.

A scene graph is a semantic representation that expresses the objects, attributes, and relationships between objects in a scene. Scene graphs play an important role in many cross modality tasks, as they are able to capture the interactions between images and texts. In this paper, we focus on scene graph modification (SGM), where the system is required to learn how to update an existing scene graph based on a natural language query. Unlike previous approaches that rebuilt the entire scene graph, we frame SGM as a graph expansion task by introducing the incremental structure expanding (ISE). ISE constructs the target graph by incrementally expanding the source graph without changing the unmodified structure. Based on ISE, we further propose a model that iterates between nodes prediction and edges prediction, inferring more accurate and harmonious expansion decisions progressively. In addition, we construct a challenging dataset that contains more complicated queries and larger scene graphs than existing datasets. Experiments on four benchmarks demonstrate the effectiveness of our approach, which surpasses the previous state-of-the-art model by large margins.

Shangjian Yin, Yu Fu, Yue Dong et al.

Post-training has become a crucial step for unlocking the capabilities of large language models, with reinforcement learning (RL) emerging as a critical paradigm. Recent RL-based post-training has increasingly split into two paradigms: reinforcement learning from human feedback (RLHF), which optimizes models using human preference signals in target domains, and reinforcement learning from verifiable rewards (RLVR), which operates in verifier-backed environments. The latter has dominated recent reasoning-oriented post-training because it delivers stronger gains and higher efficiency on domain-specific tasks (e.g., reasoning). However, although in-domain RL training achieves promising performance, it still requires a substantial amount of GPU compute, which remains a major barrier to broad adoption. In this work, we study the generalization ability of RLHF learned from scratch from a small set of interactions in open-ended environments, and investigate whether the conversational abilities it explicitly acquires can implicitly transfer to downstream tasks such as mathematical reasoning and code generation, namely GRLO. Specifically, on Qwen3-4B-Base backbone, GRLO improves the average performance across all domains from 24.1 to 63.1 with only 5K prompts and 22.7 GPU hours, requiring about $46\times$ less data and $68\times$ less compute than a strong in-domain RLVR baseline. The resulting model is even competitive with Qwen's released post-trained models which required a much larger training cost. Notably, a subsequent in-domain RLVR stage brings only selective gains, mainly on harder competition-math benchmarks. We hope GRLO offers a simple and efficient recipe for building broadly capable post-trained models. Our code and data will be available at: \href{https://github.com/SJY8460/GRLO}{https://github.com/SJY8460/GRLO}.

Abdulhamid M. Mousa, Yu Fu, Rakhmonberdi Khajiev et al.

Reinforcement learning (RL), large language models (LLMs), and vision-language models (VLMs) have been widely studied in isolation. However, existing infrastructure lacks the ability to deploy agents from different decision-making paradigms within the same environment, making it difficult to study them in hybrid multi-agent settings or to compare their behaviour fairly under identical conditions. We present MOSAIC, an open-source platform that bridges this gap by incorporating a diverse set of existing reinforcement learning environments and enabling heterogeneous agents (RL policies, LLMs, VLMs, and human players) to operate within them in ad-hoc team settings with reproducible results. MOSAIC introduces three contributions. (i) An IPC-based worker protocol that wraps both native and third-party frameworks as isolated subprocess workers, each executing its native training and inference logic unmodified, communicating through a versioned inter-process protocol. (ii) An operator abstraction that forms an agent-level interface by mapping workers to agents: each operator, regardless of whether it is backed by an RL policy, an LLM, or a human, conforms to a minimal unified interface. (iii) A deterministic cross-paradigm evaluation framework offering two complementary modes: a manual mode that advances up to N concurrent operators in lock-step under shared seeds for fine-grained visual inspection of behavioural differences, and a script mode that drives automated, long-running evaluation through declarative Python scripts, for reproducible experiments. We release MOSAIC as an open, visual-first platform to facilitate reproducible cross-paradigm research across the RL, LLM, and human-in-the-loop communities.

Yanyan Huang, Yong Wang, Kun Shi et al.

Gait recognition is widely used in diversified practical applications. Currently, the most prevalent approach is to recognize human gait from RGB images, owing to the progress of computer vision technologies. Nevertheless, the perception capability of RGB cameras deteriorates in rough circumstances, and visual surveillance may cause privacy invasion. Due to the robustness and non-invasive feature of millimeter wave (mmWave) radar, radar-based gait recognition has attracted increasing attention in recent years. In this research, we propose a Hierarchical Dynamic Network (HDNet) for gait recognition using mmWave radar. In order to explore more dynamic information, we propose point flow as a novel point clouds descriptor. We also devise a dynamic frame sampling module to promote the efficiency of computation without deteriorating performance noticeably. To prove the superiority of our methods, we perform extensive experiments on two public mmWave radar-based gait recognition datasets, and the results demonstrate that our model is superior to existing state-of-the-art methods.

Yinpeng Dong, Peng Chen, Senyou Deng et al.

The security of artificial intelligence (AI) is an important research area towards safe, reliable, and trustworthy AI systems. To accelerate the research on AI security, the Artificial Intelligence Security Competition (AISC) was organized by the Zhongguancun Laboratory, China Industrial Control Systems Cyber Emergency Response Team, Institute for Artificial Intelligence, Tsinghua University, and RealAI as part of the Zhongguancun International Frontier Technology Innovation Competition (https://www.zgc-aisc.com/en). The competition consists of three tracks, including Deepfake Security Competition, Autonomous Driving Security Competition, and Face Recognition Security Competition. This report will introduce the competition rules of these three tracks and the solutions of top-ranking teams in each track.

Ju Dong, Liding Zhang, Lei Zhang et al.

Generative policies based on diffusion and flow matching achieve strong performance in robotic manipulation by modeling multi-modal human demonstrations. However, their reliance on iterative Ordinary Differential Equation (ODE) integration introduces substantial latency, limiting high-frequency closed-loop control. Recent single-step acceleration methods alleviate this overhead but often exhibit distributional collapse, producing averaged trajectories that fail to execute coherent manipulation strategies. We propose a framework that distills a Conditional Flow Matching (CFM) expert into a fast single-step student via Implicit Maximum Likelihood Estimation (IMLE). A bi-directional Chamfer distance provides a set-level objective that promotes both mode coverage and fidelity, enabling preservation of the teacher multi-modal action distribution in a single forward pass. A unified perception encoder further integrates multi-view RGB, depth, point clouds, and proprioception into a geometry-aware representation. The resulting high-frequency control supports real-time receding-horizon re-planning and improved robustness under dynamic disturbances.

Haz Sameen Shahgir, Xiaofu Chen, Yu Fu et al.

Vision Language Models (VLMs) achieve impressive performance across a wide range of multimodal tasks. However, on some tasks that demand fine-grained visual perception, they often fail even when the required information is present in their internal representations. In this work, we demonstrate that this gap arises from their narrow training pipeline which focuses on moving visual information to the textual space. Consequently, VLMs can only reason about visual entities that can be mapped to known concepts in the language space, leaving vision-focused tasks such as visual correspondence and reasoning about novel visual entities poorly supported. As a result, VLMs are severely limited in several important multimodal capabilities because they rely on brittle, hallucinated textual descriptions of visual entities that they cannot map to textual representations. We verify this behavior through visual correspondence tasks, in which VLMs must detect matching entities between two images. Testing across semantic, shape, and face correspondence tasks, we find that VLMs perform much better when the relevant entities are nameable in language than when they are unnameable. Mechanistically, our Logit Lens analyses confirm that VLMs explicitly assign semantic labels to nameable entities and surface more unique corresponding tokens compared to unnameable entities. Furthermore, we show that teaching completely arbitrary names for unknown entities improves performance, yet task-specific finetuning yields even stronger generalization without relying on language priors. Our findings suggest that current VLM failures on visual tasks reflect learned shortcuts from their training, rather than a fundamental limitation of multimodal architectures.

Longxuan Yu, Yu Fu, Shaorong Zhang et al.

Autoregressive (AR) language models enforce a fixed left-to-right generation order, creating a fundamental limitation when the required output structure conflicts with natural reasoning (e.g., producing answers before explanations due to presentation or schema constraints). In such cases, AR models must commit to answers before generating intermediate reasoning, and this rigid constraint forces premature commitment. Masked diffusion language models (MDLMs), which iteratively refine all tokens in parallel, offer a way to decouple computation order from output structure. We validate this capability on GSM8K, Math500, and ReasonOrderQA, a benchmark we introduce with controlled difficulty and order-level evaluation. When prompts request answers before reasoning, AR models exhibit large accuracy gaps compared to standard chain-of-thought ordering (up to 67% relative drop), while MDLMs remain stable ($\leq$14% relative drop), a property we term "order robustness". Using ReasonOrderQA, we present evidence that MDLMs achieve order robustness by stabilizing simpler tokens (e.g., reasoning steps) earlier in the diffusion process than complex ones (e.g., final answers), enabling reasoning tokens to stabilize before answer commitment. Finally, we identify failure conditions where this advantage weakens, outlining the limits required for order robustness.

Yu Fu, Zefan Cai, Abedelkadir Asi et al.

Key-Value (KV) caching is a common technique to enhance the computational efficiency of Large Language Models (LLMs), but its memory overhead grows rapidly with input length. Prior work has shown that not all tokens are equally important for text generation, proposing layer-level KV cache compression to selectively retain key information. Recognizing the distinct roles of attention heads in generation, we propose HeadKV, a head-level KV cache compression method, and HeadKV-R2, which leverages a novel contextual reasoning ability estimation for compression. Our approach operates at the level of individual heads, estimating their importance for contextual QA tasks that require both retrieval and reasoning capabilities. Extensive experiments across diverse benchmarks (LongBench, LooGLE), model architectures (e.g., Llama-3-8B-Instruct, Mistral-7B-Instruct), and long-context abilities tests demonstrate that our head-level KV cache compression significantly outperforms strong baselines, particularly in low-resource settings (KV size = 64 & 128). Notably, our method retains just 1.5% of the KV cache while achieving 97% of the performance of the full KV cache on the contextual question answering benchmark. Codes are available at https://github.com/FYYFU/HeadKV

Kaiyan Zhang, Yuxin Zuo, Bingxiang He et al. · pku, tsinghua

In this paper, we survey recent advances in Reinforcement Learning (RL) for reasoning with Large Language Models (LLMs). RL has achieved remarkable success in advancing the frontier of LLM capabilities, particularly in addressing complex logical tasks such as mathematics and coding. As a result, RL has emerged as a foundational methodology for transforming LLMs into LRMs. With the rapid progress of the field, further scaling of RL for LRMs now faces foundational challenges not only in computational resources but also in algorithm design, training data, and infrastructure. To this end, it is timely to revisit the development of this domain, reassess its trajectory, and explore strategies to enhance the scalability of RL toward Artificial SuperIntelligence (ASI). In particular, we examine research applying RL to LLMs and LRMs for reasoning abilities, especially since the release of DeepSeek-R1, including foundational components, core problems, training resources, and downstream applications, to identify future opportunities and directions for this rapidly evolving area. We hope this review will promote future research on RL for broader reasoning models. Github: https://github.com/TsinghuaC3I/Awesome-RL-for-LRMs

Yu Fu, Haz Sameen Shahgir, Huanli Gong et al.

Large language models (LLMs) increasingly combine long-context processing with advanced reasoning, enabling them to retrieve and synthesize information distributed across tens of thousands of tokens. A hypothesis is that stronger reasoning capability should improve safety by helping models recognize harmful intent even when it is not stated explicitly. We test this hypothesis in long-context settings where harmful intent is implicit and must be inferred through reasoning, and find that it does not hold. We introduce compositional reasoning attacks, a new threat model in which a harmful query is decomposed into incomplete fragments that scattered throughout a long context. The model is then prompted with a neutral reasoning query that induces retrieval and synthesis, causing the harmful intent to emerge only after composition. Evaluating 14 frontier LLMs on contexts up to 64k tokens, we uncover three findings: (1) models with stronger general reasoning capability are not more robust to compositional reasoning attacks, often assembling the intent yet failing to refuse; (2) safety alignment consistently degrades as context length increases; and (3) inference-time reasoning effort is a key mitigating factor: increasing inference-time compute reduces attack success by over 50 percentage points on GPT-oss-120b model. Together, these results suggest that safety does not automatically scale with reasoning capability, especially under long-context inference.

Yuchen Liu, Wenbo Zhang, Liling Peng et al.

PET/CT imaging is pivotal in oncology and nuclear medicine, yet summarizing complex findings into precise diagnostic impressions is labor-intensive. While LLMs have shown promise in medical text generation, their capability in the highly specialized domain of PET/CT remains underexplored. We introduce PET-F2I-41K (PET Findings-to-Impression Benchmark), a large-scale benchmark for PET/CT impression generation using LLMs, constructed from over 41k real-world reports. Using PET-F2I-41K, we conduct a comprehensive evaluation of 27 models across proprietary frontier LLMs, open-source generalist models, and medical-domain LLMs, and we develop a domain-adapted 7B model (PET-F2I-7B) fine-tuned from Qwen2.5-7B-Instruct via LoRA. Beyond standard NLG metrics (e.g., BLEU-4, ROUGE-L, BERTScore), we propose three clinically grounded metrics - Entity Coverage Rate (ECR), Uncovered Entity Rate (UER), and Factual Consistency Rate (FCR) - to assess diagnostic completeness and factual reliability. Experiments reveal that neither frontier nor medical-domain LLMs perform adequately in zero-shot settings. In contrast, PET-F2I-7B achieves substantial gains (e.g., 0.708 BLEU-4) and a 3.0x improvement in entity coverage over the strongest baseline, while offering advantages in cost, latency, and privacy. Beyond this modeling contribution, PET-F2I-41K establishes a standardized evaluation framework to accelerate the development of reliable and clinically deployable reporting systems for PET/CT.

Yu Fu, Seongho Son, Ilija Bogunovic

Existing alignment paradigms remain limited in capturing the pluralistic nature of human values. Overton Pluralism addresses this gap by generating responses with diverse perspectives from a single query. This paper introduces OP-GRPO (Overton Pluralistic Group Relative Policy Optimization), a reinforcement learning framework for implicit Overton Pluralism that enables a single large language model to produce pluralistic responses without explicit prompting or modular orchestration. Our workflow consists of two main steps. First, similarity estimator training fine-tunes a Sentence Transformer for Overton Pluralism tasks to provide more accurate coverage evaluation of generated responses. Second, OP-GRPO training incorporates this similarity estimator into a dual-reward system designed to ensure both broad coverage of genuine human perspectives and the uniqueness of each perspective, thereby promoting diversity. Empirical results demonstrate a "small models, big perspective coverage" effect. The trained Qwen2.5-3B-Instruct model surpasses a 20B GPT-OSS baseline with a 37.4 percent relative accuracy gain on a Natural Language Inference benchmark, and also outperforms a modular architecture baseline with a 19.1 percent relative improvement. Additional evaluations using GPT-4.1 as a large language model judge further confirm the robustness of the approach.

Yanyan Huang, Weiqin Zhao, Yihang Chen et al.

Whole slide image (WSI) analysis is gaining prominence within the medical imaging field. Recent advances in pathology foundation models have shown the potential to extract powerful feature representations from WSIs for downstream tasks. However, these foundation models are usually designed for general-purpose pathology image analysis and may not be optimal for specific downstream tasks or cancer types. In this work, we present Concept Anchor-guided Task-specific Feature Enhancement (CATE), an adaptable paradigm that can boost the expressivity and discriminativeness of pathology foundation models for specific downstream tasks. Based on a set of task-specific concepts derived from the pathology vision-language model with expert-designed prompts, we introduce two interconnected modules to dynamically calibrate the generic image features extracted by foundation models for certain tasks or cancer types. Specifically, we design a Concept-guided Information Bottleneck module to enhance task-relevant characteristics by maximizing the mutual information between image features and concept anchors while suppressing superfluous information. Moreover, a Concept-Feature Interference module is proposed to utilize the similarity between calibrated features and concept anchors to further generate discriminative task-specific features. The extensive experiments on public WSI datasets demonstrate that CATE significantly enhances the performance and generalizability of MIL models. Additionally, heatmap and umap visualization results also reveal the effectiveness and interpretability of CATE. The source code is available at https://github.com/HKU-MedAI/CATE.

Yu Fu, Longxuan Yu, Haz Sameen Shahgir et al.

Safety alignment often improves robustness to harmful queries at the cost of reasoning ability, a tradeoff known as the safety tax. A common cause is distributional mismatch: supervised fine-tuning trains the target model on safety demonstrations produced by humans, external models, or fixed self-generated traces, rather than on trajectories sampled from its own policy. We identify off-policy training mismatch as a second source of this tax and study on-policy self-distillation for safety alignment, which we call OPSA. The model generates its own rollouts and receives dense per-token KL supervision from a frozen teacher copy of itself conditioned on a privileged safety context. Because this teacher must be safer than the sampled student trajectory, we introduce \emph{teacher flip rate}: a criterion that measures how often a privileged context converts unsafe responses into safe ones. We use this signal to search for contexts that activate latent safety reasoning rather than merely elicit safe-looking demonstrations. Across two reasoning-model families and five model scales, OPSA achieves a stronger safety--reasoning tradeoff than off-policy self-distillation and external-teacher distillation under matched data and full-parameter fine-tuning, with the largest gains on smaller models (+8.85 points on R1-Distill-1.5B and +5.49 points on Qwen3-0.6B). The gains persist across training-set sizes and adaptive jailbreak evaluations. Token-level analyses further show that OPSA concentrates updates near early compliance-decision tokens, providing a mechanism for improving safety while preserving general reasoning.

Liang Zhang, Yu Fu, Xinyi Jin

Large Language Models (LLMs) are increasingly used in math education not only as problem solvers but also as assessors of learners' reasoning. However, it remains unclear whether stronger math problem-solving ability is associated with stronger step-level assessment performance. This study examines that relationship using the GSM8K and MATH subsets of PROCESSBENCH, a human-annotated benchmark for identifying the earliest erroneous step in mathematical reasoning. We evaluate two LLM-based math tutor agent settings, instantiated with GPT-4 and GPT-5, in two independent tasks on the same math problems: solving the original problem and assessing a benchmark-provided solution by predicting the earliest erroneous step. Results show a consistent within-model pattern: assessment accuracy is substantially higher on math problem items the same model solved correctly than on items it solved incorrectly, with statistically significant associations across both models and datasets. At the same time, assessment remains more difficult than direct problem solving, especially on error-present solutions. These findings suggest that math problem-solving expertise supports stronger assessment performance, but reliable step-level diagnosis also requires additional capabilities such as step tracking, monitoring, and precise error localization. The results have implications for the design and evaluation of AI-supported Adaptive Instructional Systems (AISs) for formative assessment in math education.

Zhengxu Yu, Yu Fu, Zhiyuan He et al.

Individual agent capabilities have advanced rapidly through modular skills and tool integrations, yet multi-agent systems remain constrained by fixed team structures, tightly coupled coordination logic, and session-bound learning. We argue that this reflects a deeper absence: a principled organisational layer that governs how a workforce of agents is assembled, governed, and improved over time, decoupled from what individual agents know. To fill this gap, we introduce \emph{OneManCompany (OMC)}, a framework that elevates multi-agent systems to the organisational level. OMC encapsulates skills, tools, and runtime configurations into portable agent identities called \emph{Talents}, orchestrated through typed organisational interfaces that abstract over heterogeneous backends. A community-driven \emph{Talent Market} enables on-demand recruitment, allowing the organisation to close capability gaps and reconfigure itself dynamically during execution. Organisational decision-making is operationalised through an \emph{Explore-Execute-Review} ($\text{E}^2$R) tree search, which unifies planning, execution, and evaluation in a single hierarchical loop: tasks are decomposed top-down into accountable units and execution outcomes are aggregated bottom-up to drive systematic review and refinement. This loop provides formal guarantees on termination and deadlock freedom while mirroring the feedback mechanisms of human enterprises. Together, these contributions transform multi-agent systems from static, pre-configured pipelines into self-organising and self-improving AI organisations capable of adapting to open-ended tasks across diverse domains. Empirical evaluation on PRDBench shows that OMC achieves an $84.67\%$ success rate, surpassing the state of the art by $15.48$ percentage points, with cross-domain case studies further demonstrating its generality.

Xueyuan Duan, Yu Fu, Kun Wang

To address the problem that traditional network traffic anomaly detection algorithms do not suffi-ciently mine potential features in long time domain, an anomaly detection method based on mul-ti-scale residual features of network traffic is proposed. The original traffic is divided into subse-quences of different time spans using sliding windows, and each subsequence is decomposed and reconstructed into data sequences of different levels using wavelet transform technique; the stacked autoencoder (SAE) constructs similar feature space using normal network traffic, and gen-erates reconstructed error vector using the difference between reconstructed samples and input samples in the similar feature space; the multi-path residual group is used to learn reconstructed error The traffic classification is completed by a lightweight classifier. The experimental results show that the detection performance of the proposed method for anomalous network traffic is sig-nificantly improved compared with traditional methods; it confirms that the longer time span and more S transformation scales have positive effects on discovering potential diversity information in the original network traffic.

Huimin Wang, Leilei Ouyang, Chang Xia et al.

Generating long-horizon music videos (MVs) is frequently constrained by prohibitive computational costs and difficulty maintaining cross-shot consistency. We propose AllocMV, a hierarchical framework formulating music video synthesis as a Multiple-Choice Knapsack Problem (MCKP). AllocMV represents the video's persistent state as a compact, structured object comprising character entities, scene priors, and sharing graphs, produced by a global planner prior to realization. By estimating segment saliency from multimodal cues, a group-level MCKP solver based on dynamic programming optimally allocates resources across High-Gen, Mid-Gen, and Reuse branches. For repetitive musical motifs, we implement a divergence-based forking strategy that reuses visual prefixes to reduce costs while ensuring motif-level continuity. Evaluated via the Cost-Quality Ratio (CQR), AllocMV achieves an optimal trade-off between perceived quality and resource expenditure under strict budgetary and rhythmic constraints.

Yu Fu, Michael Stanley Smith, Anastasios Panagiotelis

The key to VI is the selection of a tractable density to approximate the Bayesian posterior. For large and complex models a common choice is to assume independence between multivariate blocks in a partition of the parameter space. While this simplifies the problem it can reduce accuracy. This paper proposes using vector copulas to capture dependence between the blocks parsimoniously. Tailored multivariate marginals are constructed using learnable transport maps. We call the resulting joint distribution a ``dependent block posterior'' approximation. Vector copula models are suggested that make tractable and flexible variational approximations. They allow for differing marginals, numbers of blocks, block sizes and forms of between block dependence. They also allow for solution of the variational optimization using efficient stochastic gradient methods. The approach is demonstrated using four different statistical models and 16 datasets which have posteriors that are challenging to approximate. This includes models that use global-local shrinkage priors for regularization, and hierarchical models for smoothing and heteroscedastic time series. In all cases, our method produces more accurate posterior approximations than benchmark VI methods that either assume block independence or factor-based dependence, at limited additional computational cost. A python package implementing the method is available on GitHub at https://github.com/YuFuOliver/VCVI_Rep_PyPackage.

Yu Fu, Jie He, Yifan Yang et al.

Meta learning has been widely used to exploit rich-resource source tasks to improve the performance of low-resource target tasks. Unfortunately, most existing meta learning approaches treat different source tasks equally, ignoring the relatedness of source tasks to the target task in knowledge transfer. To mitigate this issue, we propose a reinforcement-based multi-source meta-transfer learning framework (Meta-RTL) for low-resource commonsense reasoning. In this framework, we present a reinforcement-based approach to dynamically estimating source task weights that measure the contribution of the corresponding tasks to the target task in the meta-transfer learning. The differences between the general loss of the meta model and task-specific losses of source-specific temporal meta models on sampled target data are fed into the policy network of the reinforcement learning module as rewards. The policy network is built upon LSTMs that capture long-term dependencies on source task weight estimation across meta learning iterations. We evaluate the proposed Meta-RTL using both BERT and ALBERT as the backbone of the meta model on three commonsense reasoning benchmark datasets. Experimental results demonstrate that Meta-RTL substantially outperforms strong baselines and previous task selection strategies and achieves larger improvements on extremely low-resource settings.

Yichi Zhang, Le Xue, Bichun Xu et al.

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to extremely limited annotation scenarios, they fail to maintain robust competitive performance in complex imaging modalities. In this paper, we propose SemiSAM-O1, an annotation-efficient framework using only one annotated template image for segmentation. SemiSAM-O1 extends the specialist-generalist collaborative learning framework to the extreme one-label setting by fully exploiting the foundation model's feature representation capability beyond its prompting interface. SemiSAM-O1 operates in two stages. In the first stage, the foundation model's encoder extracts dense features from all volumes, and class prototypes derived from the single annotated template are propagated to the unlabeled pool via feature similarity to produce coarse initial pseudo-labels. In the second stage, an iterative training-and-refinement loop progressively improves both the segmentation model and the pseudo-labels over multiple rounds, where each round trains the model from scratch on current pseudo-labels and generates updated predictions with voxel-wise uncertainty estimates. An uncertainty-guided refinement step further leverages the foundation model's global feature space to correct high-uncertainty regions by aggregating labels from their most similar confident neighbors, establishing a virtuous cycle of mutual improvement. Extensive experiments on a wide range of segmentation tasks across different modalities and anatomical targets demonstrate that SemiSAM-O1 significantly narrows the performance gap between one-label semi-supervised learning and full supervision, while significantly reducing the computational overhead of online foundation model inference.

Yu Fu, Yufei Li, Wen Xiao et al.

Recent developments in balancing the usefulness and safety of Large Language Models (LLMs) have raised a critical question: Are mainstream NLP tasks adequately aligned with safety consideration? Our study, focusing on safety-sensitive documents obtained through adversarial attacks, reveals significant disparities in the safety alignment of various NLP tasks. For instance, LLMs can effectively summarize malicious long documents but often refuse to translate them. This discrepancy highlights a previously unidentified vulnerability: attacks exploiting tasks with weaker safety alignment, like summarization, can potentially compromise the integrity of tasks traditionally deemed more robust, such as translation and question-answering (QA). Moreover, the concurrent use of multiple NLP tasks with lesser safety alignment increases the risk of LLMs inadvertently processing harmful content. We demonstrate these vulnerabilities in various safety-aligned LLMs, particularly Llama2 models, Gemini and GPT-4, indicating an urgent need for strengthening safety alignments across a broad spectrum of NLP tasks.

Yongrui Yu, Hanyu Chen, Zitian Zhang et al.

Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and indistinguishable lesions, and limited annotated data. To address these problems, we present a pipeline that integrates the conditional diffusion model for lymph node generation and the nnU-Net model for lymph node segmentation to improve the segmentation performance of abdominal lymph nodes through synthesizing a diversity of realistic abdominal lymph node data. We propose LN-DDPM, a conditional denoising diffusion probabilistic model (DDPM) for lymph node (LN) generation. LN-DDPM utilizes lymph node masks and anatomical structure masks as model conditions. These conditions work in two conditioning mechanisms: global structure conditioning and local detail conditioning, to distinguish between lymph nodes and their surroundings and better capture lymph node characteristics. The obtained paired abdominal lymph node images and masks are used for the downstream segmentation task. Experimental results on the abdominal lymph node datasets demonstrate that LN-DDPM outperforms other generative methods in the abdominal lymph node image synthesis and better assists the downstream abdominal lymph node segmentation task.

Yuchen Fan, Kaiyan Zhang, Heng Zhou et al. · pku, tsinghua

We investigate the potential of large language models (LLMs) to serve as efficient simulators for agentic search tasks in reinforcement learning (RL), thereby reducing dependence on costly interactions with external search engines. To this end, we first quantify the intrinsic search capability of LLMs via structured prompting and repeated sampling, which we term Self-Search. Our results reveal that LLMs exhibit strong scaling behavior with respect to the inference budget, achieving high pass@k on question-answering benchmarks, including the challenging BrowseComp task. Building on these observations, we introduce Self-Search RL (SSRL), which enhances LLMs' Self-Search capability through format-based and rule-based rewards. SSRL enables models to iteratively refine their knowledge utilization internally, without requiring access to external tools. Empirical evaluations demonstrate that SSRL-trained policy models provide a cost-effective and stable environment for search-driven RL training, reducing reliance on external search engines and facilitating robust sim-to-real transfer. We draw the following conclusions: 1) LLMs possess world knowledge that can be effectively elicited to achieve high performance; 2) SSRL demonstrates the potential of leveraging internal knowledge to reduce hallucination; 3) SSRL-trained models integrate seamlessly with external search engines without additional effort. Our findings highlight the potential of LLMs to support more scalable RL agent training.

Yichi Zhang, Bohao Lv, Le Xue et al.

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an appealing strategy due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods. Beyond existing model-centric advancements of SSL by designing novel regularization strategies, we anticipate a paradigmatic shift due to the emergence of promptable segmentation foundation models with universal segmentation capabilities using positional prompts represented by Segment Anything Model (SAM). In this paper, we present SemiSAM+, a foundation model-driven SSL framework to efficiently learn from limited labeled data for medical image segmentation. SemiSAM+ consists of one or multiple promptable foundation models as generalist models, and a trainable task-specific segmentation model as specialist model. For a given new segmentation task, the training is based on the specialist-generalist collaborative learning procedure, where the trainable specialist model delivers positional prompts to interact with the frozen generalist models to acquire pseudo-labels, and then the generalist model output provides the specialist model with informative and efficient supervision which benefits the automatic segmentation and prompt generation in turn. Extensive experiments on two public datasets and one in-house clinical dataset demonstrate that SemiSAM+ achieves significant performance improvement, especially under extremely limited annotation scenarios, and shows strong efficiency as a plug-and-play strategy that can be easily adapted to different specialist and generalist models.

Jie He, Yu Fu

Commonsense reasoning (CR) has been studied in many pieces of domain and has achieved great progress with the aid of large datasets. Unfortunately, most existing CR datasets are built in English, so most previous work focus on English. Furthermore, as the annotation of commonsense reasoning is costly, it is impossible to build a large dataset for every novel task. Therefore, there are growing appeals for Cross-lingual Low-Resource Commonsense Reasoning, which aims to leverage diverse existed English datasets to help the model adapt to new cross-lingual target datasets with limited labeled data. In this paper, we propose a multi-source adapter for cross-lingual low-resource Commonsense Reasoning (MetaXCR). In this framework, we first extend meta learning by incorporating multiple training datasets to learn a generalized task adapters across different tasks. Then, we further introduce a reinforcement-based sampling strategy to help the model sample the source task that is the most helpful to the target task. Finally, we introduce two types of cross-lingual meta-adaption methods to enhance the performance of models on target languages. Extensive experiments demonstrate MetaXCR is superior over state-of-the-arts, while being trained with fewer parameters than other work.

Yu Fu, Dennis Bromley, Vidya Setlur

Data-driven storytelling has gained prominence in journalism and other data reporting fields. However, the process of creating these stories remains challenging, often requiring the integration of effective visualizations with compelling narratives to form a cohesive, interactive presentation. To help streamline this process, we present an integrated authoring framework and system, DataWeaver, that supports both visualization-to-text and text-to-visualization composition. DataWeaver enables users to create data narratives anchored to data facts derived from "call-out" interactions, i.e., user-initiated highlights of visualization elements that prompt relevant narrative content. In addition to this "vis-to-text" composition, DataWeaver also supports a "text-initiated" approach, generating relevant interactive visualizations from existing narratives. Key findings from an evaluation with 13 participants highlighted the utility and usability of DataWeaver and the effectiveness of its integrated authoring framework. The evaluation also revealed opportunities to enhance the framework by refining filtering mechanisms and visualization recommendations and better support authoring creativity by introducing advanced customization options.

Ju Dong, Lei Zhang, Liding Zhang et al.

Mobile manipulation requires the coordinated control of a mobile base and a robotic arm while simultaneously perceiving both global scene context and fine-grained object details. Existing single-view approaches often fail in unstructured environments due to limited fields of view, exploration, and generalization abilities. Moreover, classical controllers, although stable, struggle with efficiency and manipulability near singularities. To address these challenges, we propose M4Diffuser, a hybrid framework that integrates a Multi-View Diffusion Policy with a novel Reduced and Manipulability-aware QP (ReM-QP) controller for mobile manipulation. The diffusion policy leverages proprioceptive states and complementary camera perspectives with both close-range object details and global scene context to generate task-relevant end-effector goals in the world frame. These high-level goals are then executed by the ReM-QP controller, which eliminates slack variables for computational efficiency and incorporates manipulability-aware preferences for robustness near singularities. Comprehensive experiments in simulation and real-world environments show that M4Diffuser achieves 7 to 56 percent higher success rates and reduces collisions by 3 to 31 percent over baselines. Our approach demonstrates robust performance for smooth whole-body coordination, and strong generalization to unseen tasks, paving the way for reliable mobile manipulation in unstructured environments. Details of the demo and supplemental material are available on our project website https://sites.google.com/view/m4diffuser.

Qinyan Zhang, Xinping Lei, Ruijie Miao et al.

Large Language Models (LLMs) achieve strong performance on diverse tasks but often exhibit cognitive inertia, struggling to follow instructions that conflict with the standardized patterns learned during supervised fine-tuning (SFT). To evaluate this limitation, we propose Inverse IFEval, a benchmark that measures models Counter-intuitive Abilitytheir capacity to override training-induced biases and comply with adversarial instructions. Inverse IFEval introduces eight types of such challenges, including Question Correction, Intentional Textual Flaws, Code without Comments, and Counterfactual Answering. Using a human-in-the-loop pipeline, we construct a dataset of 1012 high-quality Chinese and English questions across 23 domains, evaluated under an optimized LLM-as-a-Judge framework. Experiments on existing leading LLMs demonstrate the necessity of our proposed Inverse IFEval benchmark. Our findings emphasize that future alignment efforts should not only pursue fluency and factual correctness but also account for adaptability under unconventional contexts. We hope that Inverse IFEval serves as both a diagnostic tool and a foundation for developing methods that mitigate cognitive inertia, reduce overfitting to narrow patterns, and ultimately enhance the instruction-following reliability of LLMs in diverse and unpredictable real-world scenarios.

Yu Fu, Haz Sameen Shahgir, Hui Liu et al.

Recent advances in long-context models (LCMs), designed to handle extremely long input contexts, primarily focus on utilizing external contextual information, often leaving the influence of large language models' intrinsic knowledge underexplored. In this work, we investigate how this intrinsic knowledge affects content generation and demonstrate that its impact becomes increasingly pronounced as context length extends. Furthermore, we show that the model's ability to utilize intrinsic knowledge, which we call intrinsic retrieval ability, does not improve simultaneously with its ability to leverage contextual knowledge through extrinsic retrieval ability. Moreover, better extrinsic retrieval can interfere with the model's ability to use its own knowledge effectively, limiting its full potential. To bridge this gap, we design a simple yet effective Hybrid Needle-in-a-Haystack test that evaluates models based on their capabilities across both retrieval abilities, rather than solely emphasizing extrinsic retrieval ability. Our experimental results reveal that Qwen-2.5 models significantly outperform Llama-3.1 models, demonstrating superior intrinsic retrieval ability. Moreover, even the more powerful Llama-3.1-70B-Instruct model fails to exhibit better performance under LCM conditions, highlighting the importance of evaluating models from a dual-retrieval perspective.

Yufei Li, Yu Fu, Yue Dong et al.

Large language models (LLMs) deployed on edge servers are increasingly used in latency-sensitive applications such as personalized assistants, recommendation, and content moderation. However, the non-stationary nature of user data necessitates frequent retraining, which introduces a fundamental tension between inference latency and model accuracy under constrained GPU resources. Existing retraining strategies either delay model updates, over-commit resources to retraining, or overlook iteration-level retraining granularity. In this paper, we identify that iteration-level scheduling is crucial for adapting retraining frequency to model drift without violating service-level objectives (SLOs). We propose MACE, a hybrid LLM system that colocates concurrent inference (prefill, decode) and fine-tuning, with intelligent memory management to maximize task performance while promising inference throughput. MACE leverages the insight that not all model updates equally affect output alignment and allocates GPU cycles accordingly to balance throughput, latency, and update freshness. Our trace-driven evaluation shows that MACE matches or exceeds continuous retraining while reducing inference latency by up to 63% and maintaining throughput under resource constraints. Compared to periodic retraining, MACE improves latency breakdown across prefill, decode, and finetune stages, and sustains GPU utilization above 85% in NVIDIA AGX Orin. These results demonstrate that iteration-level hybrid scheduling is a promising direction for deploying LLMs with continual learning capabilities on edge platforms.

Yu Fu, Linyue Cai, Ruoyu Wu et al.

Personalized recipe recommendation faces challenges in handling fuzzy user intent, ensuring semantic accuracy, and providing sufficient detail coverage. We propose ChefMind, a hybrid architecture combining Chain of Exploration (CoE), Knowledge Graph (KG), Retrieval-Augmented Generation (RAG), and a Large Language Model (LLM). CoE refines ambiguous queries into structured conditions, KG offers semantic reasoning and interpretability, RAG supplements contextual culinary details, and LLM integrates outputs into coherent recommendations. We evaluate ChefMind on the Xiachufang dataset and manually annotated queries, comparing it with LLM-only, KG-only, and RAG-only baselines. Results show that ChefMind achieves superior performance in accuracy, relevance, completeness, and clarity, with an average score of 8.7 versus 6.4-6.7 for ablation models. Moreover, it reduces unprocessed queries to 1.6%, demonstrating robustness in handling fuzzy demands.

Yiran Luo, Het Patel, Yu Fu et al.

Recent research has shown that pruning large-scale language models for inference is an effective approach to improving model efficiency, significantly reducing model weights with minimal impact on performance. Interestingly, pruning can sometimes even enhance accuracy by removing noise that accumulates during training, particularly through matrix decompositions. However, recent work has primarily focused on single matrix decompositions or lower precision techniques, which may fail to fully capture structural patterns. To address these limitations, we introduce TRAWL (Tensor Reduced and Approximated Weights for Large Language Models), a technique that applies tensor decomposition across multiple weight matrices to effectively denoise LLMs by capturing global structural patterns. Our experiments show that TRAWL improves model performance by up to 16% over baseline models on benchmark datasets, without requiring additional data, training, or fine-tuning.

Jingcheng Jiang, Haiyin Piao, Yu Fu et al.

Reviewing the previous work of diversity Rein-forcement Learning,diversity is often obtained via an augmented loss function,which requires a balance between reward and diversity.Generally,diversity optimization algorithms use Multi-armed Bandits algorithms to select the coefficient in the pre-defined space. However, the dynamic distribution of reward signals for MABs or the conflict between quality and diversity limits the performance of these methods. We introduce the Phasic Diversity Optimization (PDO) algorithm, a Population-Based Training framework that separates reward and diversity training into distinct phases instead of optimizing a multi-objective function. In the auxiliary phase, agents with poor performance diversified via determinants will not replace the better agents in the archive. The decoupling of reward and diversity allows us to use an aggressive diversity optimization in the auxiliary phase without performance degradation. Furthermore, we construct a dogfight scenario for aerial agents to demonstrate the practicality of the PDO algorithm. We introduce two implementations of PDO archive and conduct tests in the newly proposed adversarial dogfight and MuJoCo simulations. The results show that our proposed algorithm achieves better performance than baselines.

Xi Chen, MingKe You, Li Wang et al.

The efficacy of large language models (LLMs) in domain-specific medicine, particularly for managing complex diseases such as osteoarthritis (OA), remains largely unexplored. This study focused on evaluating and enhancing the clinical capabilities of LLMs in specific domains, using osteoarthritis (OA) management as a case study. A domain specific benchmark framework was developed, which evaluate LLMs across a spectrum from domain-specific knowledge to clinical applications in real-world clinical scenarios. DocOA, a specialized LLM tailored for OA management that integrates retrieval-augmented generation (RAG) and instruction prompts, was developed. The study compared the performance of GPT-3.5, GPT-4, and a specialized assistant, DocOA, using objective and human evaluations. Results showed that general LLMs like GPT-3.5 and GPT-4 were less effective in the specialized domain of OA management, particularly in providing personalized treatment recommendations. However, DocOA showed significant improvements. This study introduces a novel benchmark framework which assesses the domain-specific abilities of LLMs in multiple aspects, highlights the limitations of generalized LLMs in clinical contexts, and demonstrates the potential of tailored approaches for developing domain-specific medical LLMs.

Yu Fu, Yanyan Huang, Shunjie Dong et al.

Deep neural networks (DNN) have been designed to predict the chronological age of a healthy brain from T1-weighted magnetic resonance images (T1 MRIs), and the predicted brain age could serve as a valuable biomarker for the early detection of development-related or aging-related disorders. Recent DNN models for brain age estimations usually rely too much on large sample sizes and complex network structures for multi-stage feature refinement. However, in clinical application scenarios, researchers usually cannot obtain thousands or tens of thousands of MRIs in each data center for thorough training of these complex models. This paper proposes a simple fully convolutional network (SFCNeXt) for brain age estimation in small-sized cohorts with biased age distributions. The SFCNeXt consists of Single Pathway Encoded ConvNeXt (SPEC) and Hybrid Ranking Loss (HRL), aiming to estimate brain ages in a lightweight way with a sufficient exploration of MRI, age, and ranking features of each batch of subjects. Experimental results demonstrate the superiority and efficiency of our approach.

Yu Fu, Shunjie Dong, Yi Liao et al.

18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET) imaging usually needs a full-dose radioactive tracer to obtain satisfactory diagnostic results, which raises concerns about the potential health risks of radiation exposure, especially for pediatric patients. Reconstructing the low-dose PET (L-PET) images to the high-quality full-dose PET (F-PET) ones is an effective way that both reduces the radiation exposure and remains diagnostic accuracy. In this paper, we propose a resource-efficient deep learning framework for L-PET reconstruction and analysis, referred to as transGAN-SDAM, to generate F-PET from corresponding L-PET, and quantify the standard uptake value ratios (SUVRs) of these generated F-PET at whole brain. The transGAN-SDAM consists of two modules: a transformer-encoded Generative Adversarial Network (transGAN) and a Spatial Deformable Aggregation Module (SDAM). The transGAN generates higher quality F-PET images, and then the SDAM integrates the spatial information of a sequence of generated F-PET slices to synthesize whole-brain F-PET images. Experimental results demonstrate the superiority and rationality of our approach.

Hayeong Song, Yu Fu, Bahador Saket et al.

When performing data analysis, people often confront data sets containing missing values. We conducted an empirical study to understand the effects of visualizing those missing values on participants' decision-making processes while performing a visual data exploration task. More specifically, our study participants purchased a hypothetical portfolio of stocks based on a dataset where some stocks had missing values for attributes such as PE ratio, beta, and EPS. The experiment used scatterplots to communicate the stock data. For one group of participants, stocks with missing values simply were not shown, while the second group saw such stocks depicted with estimated values as points with error bars. We measured participants' cognitive load involved in decision-making with data with missing values. Our results indicate that their decision-making workflow was different across two conditions.

Yu Fu, TianYang Xu, XiaoJun Wu et al.

The Transformer architecture has witnessed a rapid development in recent years, outperforming the CNN architectures in many computer vision tasks, as exemplified by the Vision Transformers (ViT) for image classification. However, existing visual transformer models aim to extract semantic information for high-level tasks, such as classification and detection.These methods ignore the importance of the spatial resolution of the input image, thus sacrificing the local correlation information of neighboring pixels. In this paper, we propose a Patch Pyramid Transformer(PPT) to effectively address the above issues.Specifically, we first design a Patch Transformer to transform the image into a sequence of patches, where transformer encoding is performed for each patch to extract local representations. In addition, we construct a Pyramid Transformer to effectively extract the non-local information from the entire image. After obtaining a set of multi-scale, multi-dimensional, and multi-angle features of the original image, we design the image reconstruction network to ensure that the features can be reconstructed into the original input. To validate the effectiveness, we apply the proposed Patch Pyramid Transformer to image fusion tasks. The experimental results demonstrate its superior performance, compared to the state-of-the-art fusion approaches, achieving the best results on several evaluation indicators. Thanks to the underlying representational capacity of the PPT network, it can directly be applied to different image fusion tasks without redesigning or retraining the network.