Washington Cunha

Pablo Cecilio, Antônio Perreira, Juliana Santos Rosa Viegas et al.

Pharmaceutical patents play an important role by protecting the innovation from copies but also drive researchers to innovate, create new products, and promote disruptive innovations focusing on collective health. The study of patent management usually refers to an exhaustive manual search. This happens, because patent documents are complex with a lot of details regarding the claims and methodology/results explanation of the invention. To mitigate the manual search, we proposed PATopics, a framework specially designed to extract relevant information for Pharmaceutical patents. PATopics is composed of four building blocks that extract textual information from the patents, build relevant topics that are capable of summarizing the patents, correlate these topics with useful patent characteristics and then, summarize the information in a friendly web interface to final users. The general contributions of PATopics are its ability to centralize patents and to manage patents into groups based on their similarities. We extensively analyzed the framework using 4,832 pharmaceutical patents concerning 809 molecules patented by 478 companies. In our analysis, we evaluate the use of the framework considering the demands of three user profiles -- researchers, chemists, and companies. We also designed four real-world use cases to evaluate the framework's applicability. Our analysis showed how practical and helpful PATopics are in the pharmaceutical scenario.

Claudio M. V. de Andrade, Washington Cunha, Davi Reis et al.

Transformer models have achieved state-of-the-art results, with Large Language Models (LLMs), an evolution of first-generation transformers (1stTR), being considered the cutting edge in several NLP tasks. However, the literature has yet to conclusively demonstrate that LLMs consistently outperform 1stTRs across all NLP tasks. This study compares three 1stTRs (BERT, RoBERTa, and BART) with two open LLMs (Llama 2 and Bloom) across 11 sentiment analysis datasets. The results indicate that open LLMs may moderately outperform or match 1stTRs in 8 out of 11 datasets but only when fine-tuned. Given this substantial cost for only moderate gains, the practical applicability of these models in cost-sensitive scenarios is questionable. In this context, a confidence-based strategy that seamlessly integrates 1stTRs with open LLMs based on prediction certainty is proposed. High-confidence documents are classified by the more cost-effective 1stTRs, while uncertain cases are handled by LLMs in zero-shot or few-shot modes, at a much lower cost than fine-tuned versions. Experiments in sentiment analysis demonstrate that our solution not only outperforms 1stTRs, zero-shot, and few-shot LLMs but also competes closely with fine-tuned LLMs at a fraction of the cost.

Washington Cunha, Celso França, Leonardo Rocha et al.

There is a niche of companies responsible for intermediating the purchase of large batches of varied products for other companies, for which the main challenge is to perform product description standardization, i.e., matching an item described by a client with a product described in a catalog. The problem is complex since the client's product description may be: (1) potentially noisy; (2) short and uninformative (e.g., missing information about model and size); and (3) cross-language. In this paper, we formalize this problem as a ranking task: given an initial client product specification (query), return the most appropriate standardized descriptions (response). In this paper, we propose TPDR, a two-step Transformer-based Product and Class Description Retrieval method that is able to explore the semantic correspondence between IS and SD, by exploiting attention mechanisms and contrastive learning. First, TPDR employs the transformers as two encoders sharing the embedding vector space: one for encoding the IS and another for the SD, in which corresponding pairs (IS, SD) must be close in the vector space. Closeness is further enforced by a contrastive learning mechanism leveraging a specialized loss function. TPDR also exploits a (second) re-ranking step based on syntactic features that are very important for the exact matching (model, dimension) of certain products that may have been neglected by the transformers. To evaluate our proposal, we consider 11 datasets from a real company, covering different application contexts. Our solution was able to retrieve the correct standardized product before the 5th ranking position in 71% of the cases and its correct category in the first position in 80% of the situations. Moreover, the effectiveness gains over purely syntactic or semantic baselines reach up to 3.7 times, solving cases that none of the approaches in isolation can do by themselves.

Washington Cunha, Leonardo Rocha, Marcos André Gonçalves

Progress in Natural Language Processing (NLP) has been dictated by the rule of more: more data, more computing power and more complexity, best exemplified by the Large Language Models. However, training (or fine-tuning) large dense models for specific applications usually requires significant amounts of computing resources. This \textbf{Ph.D. dissertation} focuses on an under-investi\-gated NLP data engineering technique, whose potential is enormous in the current scenario known as Instance Selection (IS). The IS goal is to reduce the training set size by removing noisy or redundant instances while maintaining the effectiveness of the trained models and reducing the training process cost. We provide a comprehensive and scientifically sound comparison of IS methods applied to an essential NLP task -- Automatic Text Classification (ATC), considering several classification solutions and many datasets. Our findings reveal a significant untapped potential for IS solutions. We also propose two novel IS solutions that are noise-oriented and redundancy-aware, specifically designed for large datasets and transformer architectures. Our final solution achieved an average reduction of 41\% in training sets, while maintaining the same levels of effectiveness in all datasets. Importantly, our solutions demonstrated speedup improvements of 1.67x (up to 2.46x), making them scalable for datasets with hundreds of thousands of documents.