Manuel Lage Cañellas

Constantino Álvarez Casado, Manuel Lage Cañellas, Miguel Bordallo López

Depression is a mental illness that may be harmful to an individual's health. The detection of mental health disorders in the early stages and a precise diagnosis are critical to avoid social, physiological, or psychological side effects. This work analyzes physiological signals to observe if different depressive states have a noticeable impact on the blood volume pulse (BVP) and the heart rate variability (HRV) response. Although typically, HRV features are calculated from biosignals obtained with contact-based sensors such as wearables, we propose instead a novel scheme that directly extracts them from facial videos, just based on visual information, removing the need for any contact-based device. Our solution is based on a pipeline that is able to extract complete remote photoplethysmography signals (rPPG) in a fully unsupervised manner. We use these rPPG signals to calculate over 60 statistical, geometrical, and physiological features that are further used to train several machine learning regressors to recognize different levels of depression. Experiments on two benchmark datasets indicate that this approach offers comparable results to other audiovisual modalities based on voice or facial expression, potentially complementing them. In addition, the results achieved for the proposed method show promising and solid performance that outperforms hand-engineered methods and is comparable to deep learning-based approaches.

Manuel Lage Cañellas, Constantino Álvarez Casado, Le Nguyen et al.

Deep learning models have shown promising results in recognizing depressive states using video-based facial expressions. While successful models typically leverage using 3D-CNNs or video distillation techniques, the different use of pretraining, data augmentation, preprocessing, and optimization techniques across experiments makes it difficult to make fair architectural comparisons. We propose instead to enhance two simple models based on ResNet-50 that use only static spatial information by using two specific face alignment methods and improved data augmentation, optimization, and scheduling techniques. Our extensive experiments on benchmark datasets obtain similar results to sophisticated spatio-temporal models for single streams, while the score-level fusion of two different streams outperforms state-of-the-art methods. Our findings suggest that specific modifications in the preprocessing and training process result in noticeable differences in the performance of the models and could hide the actual originally attributed to the use of different neural network architectures.

Constantino Álvarez Casado, Manuel Lage Cañellas, Matteo Pedone et al.

Respiratory diseases remain a leading cause of mortality worldwide, highlighting the need for faster and more accurate diagnostic tools. This work presents a novel approach leveraging digital stethoscope technology for automatic respiratory disease classification and biometric analysis. Our approach has the potential to significantly enhance traditional auscultation practices. By leveraging one of the largest publicly available medical database of respiratory sounds, we train machine learning models to classify various respiratory health conditions. Our method differs from conventional methods by using Empirical Mode Decomposition (EMD) and spectral analysis techniques to isolate clinically relevant biosignals embedded within acoustic data captured by digital stethoscopes. This approach focuses on information closely tied to cardiovascular and respiratory patterns within the acoustic data. Spectral analysis and filtering techniques isolate Intrinsic Mode Functions (IMFs) strongly correlated with these physiological phenomena. These biosignals undergo a comprehensive feature extraction process for predictive modeling. These features then serve as input to train several machine learning models for both classification and regression tasks. Our approach achieves high accuracy in both binary classification (89% balanced accuracy for healthy vs. diseased) and multi-class classification (72% balanced accuracy for specific diseases like pneumonia and COPD). For the first time, this work introduces regression models capable of estimating age and body mass index (BMI) based solely on acoustic data, as well as a model for sex classification. Our findings underscore the potential of intelligent digital stethoscopes to significantly enhance assistive and remote diagnostic capabilities, contributing to advancements in digital health, telehealth, and remote patient monitoring.

Constantino Álvarez Casado, Mohammad Rahman, Sasan Sharifipour et al.

Thermal infrared imaging captures skin temperature changes driven by autonomic regulation and can potentially provide contactless estimation of electrodermal activity (EDA), heart rate (HR), and breathing rate (BR). While visible-light methods address HR and BR, they cannot access EDA, a standard marker of sympathetic activation. This paper characterizes the extraction of these three biosignals from facial thermal video using a signal-processing pipeline that tracks anatomical regions, applies spatial aggregation, and separates slow sudomotor trends from faster cardiorespiratory components. For HR, we apply an orthogonal matrix image transformation (OMIT) decomposition across multiple facial regions of interest (ROIs), and for BR we average nasal and cheek signals before spectral peak detection. We evaluate 288 EDA configurations and the HR/BR pipeline on 31 sessions from the public SIMULATOR STUDY 1 (SIM1) driver monitoring dataset. The best fixed EDA configuration (nose region, exponential moving average) reaches a mean absolute correlation of $0.40 \pm 0.23$ against palm EDA, with individual sessions reaching 0.89. BR estimation achieves a mean absolute error of $3.1 \pm 1.1$ bpm, while HR estimation yields $13.8 \pm 7.5$ bpm MAE, limited by the low camera frame rate (7.5 Hz). We report signal polarity alternation across sessions, short thermodynamic latency for well-tracked signals, and condition-dependent and demographic effects on extraction quality. These results provide baseline performance bounds and design guidance for thermal contactless biosignal estimation.

Nhi Nguyen, Constantino Álvarez Casado, Le Nguyen et al.

Video-based respiratory rate (RR) estimation is often unreliable due to inconsistent signal quality across extraction methods. We present a predictive, quality-aware framework that integrates heterogeneous signal sources with dynamic assessment of reliability. Ten signals are extracted from facial remote photoplethysmography (rPPG), upper-body motion, and deep learning pipelines, and analyzed using four spectral estimators: Welch's method, Multiple Signal Classification (MUSIC), Fast Fourier Transform (FFT), and peak detection. Segment-level quality indices are then used to train machine learning models that predict accuracy or select the most reliable signal. This enables adaptive signal fusion and quality-based segment filtering. Experiments on three public datasets (OMuSense-23, COHFACE, MAHNOB-HCI) show that the proposed framework achieves lower RR estimation errors than individual methods in most cases, with performance gains depending on dataset characteristics. These findings highlight the potential of quality-driven predictive modeling to deliver scalable and generalizable video-based respiratory monitoring solutions.

Manuel Lage Cañellas, Constantino Álvarez Casado, Le Nguyen et al.

Exercise-induced fatigue resulting from physical activity can be an early indicator of overtraining, illness, or other health issues. In this article, we present an automated method for estimating exercise-induced fatigue levels through the use of thermal imaging and facial analysis techniques utilizing deep learning models. Leveraging a novel dataset comprising over 400,000 thermal facial images of rested and fatigued users, our results suggest that exercise-induced fatigue levels could be predicted with only one static thermal frame with an average error smaller than 15\%. The results emphasize the viability of using thermal imaging in conjunction with deep learning for reliable exercise-induced fatigue estimation.

Sasan Sharifipour, Constantino Álvarez Casado, Manuel Lage Cañellas et al.

Loss functions are fundamental to learning accurate 3D point cloud models, yet common choices trade geometric fidelity for computational cost. Chamfer Distance is efficient but permits many-to-one correspondences, while Earth Mover Distance better reflects one-to-one transport at high computational cost. APML approximates transport with differentiable Sinkhorn iterations and an analytically derived temperature, but its dense formulation scales quadratically in memory. We present CUDA-APML, a sparse GPU implementation that thresholds negligible assignments and runs adaptive softmax, bidirectional symmetrization, and Sinkhorn normalization directly in COO form. This yields near-linear memory scaling and preserves gradients on the stored support, while pairwise distance evaluation remains quadratic in the current implementation. On ShapeNet and MM-Fi, CUDA-APML matches dense APML within a small tolerance while reducing peak GPU memory by 99.9%. Code available at: https://github.com/Multimodal-Sensing-Lab/apml

Le Ngu Nguyen, Praneeth Susarla, Anirban Mukherjee et al.

Indoor human monitoring systems leverage a wide range of sensors, including cameras, radio devices, and inertial measurement units, to collect extensive data from users and the environment. These sensors contribute diverse data modalities, such as video feeds from cameras, received signal strength indicators and channel state information from WiFi devices, and three-axis acceleration data from inertial measurement units. In this context, we present a comprehensive survey of multimodal approaches for indoor human monitoring systems, with a specific focus on their relevance in elderly care. Our survey primarily highlights non-contact technologies, particularly cameras and radio devices, as key components in the development of indoor human monitoring systems. Throughout this article, we explore well-established techniques for extracting features from multimodal data sources. Our exploration extends to methodologies for fusing these features and harnessing multiple modalities to improve the accuracy and robustness of machine learning models. Furthermore, we conduct comparative analysis across different data modalities in diverse human monitoring tasks and undertake a comprehensive examination of existing multimodal datasets. This extensive survey not only highlights the significance of indoor human monitoring systems but also affirms their versatile applications. In particular, we emphasize their critical role in enhancing the quality of elderly care, offering valuable insights into the development of non-contact monitoring solutions applicable to the needs of aging populations.

Manuel Lage Cañellas, Le Nguyen, Anirban Mukherjee et al.

In the domain of non-contact biometrics and human activity recognition, the lack of a versatile, multimodal dataset poses a significant bottleneck. To address this, we introduce the Oulu Multi Sensing (OMuSense-23) dataset that includes biosignals obtained from a mmWave radar, and an RGB-D camera. The dataset features data from 50 individuals in three distinct poses -- standing, sitting, and lying down -- each featuring four specific breathing pattern activities: regular breathing, reading, guided breathing, and apnea, encompassing both typical situations (e.g., sitting with normal breathing) and critical conditions (e.g., lying down without breathing). In our work, we present a detailed overview of the OMuSense-23 dataset, detailing the data acquisition protocol, describing the process for each participant. In addition, we provide, a baseline evaluation of several data analysis tasks related to biometrics, breathing pattern recognition and pose identification. Our results achieve a pose identification accuracy of 87\% and breathing pattern activity recognition of 83\% using features extracted from biosignals. The OMuSense-23 dataset is publicly available as resource for other researchers and practitioners in the field.

Le Ngu Nguyen, Constantino Álvarez Casado, Manuel Lage Cañellas et al.

Radio frequency (RF) signals have facilitated the development of non-contact human monitoring tasks, such as vital signs measurement, activity recognition, and user identification. In some specific scenarios, an RF signal analysis framework may prioritize the performance of one task over that of others. In response to this requirement, we employ a multi-objective optimization approach inspired by biological principles to select discriminative features that enhance the accuracy of breathing patterns recognition while simultaneously impeding the identification of individual users. This approach is validated using a novel vital signs dataset consisting of 50 subjects engaged in four distinct breathing patterns. Our findings indicate a remarkable result: a substantial divergence in accuracy between breathing recognition and user identification. As a complementary viewpoint, we present a contrariwise result to maximize user identification accuracy and minimize the system's capacity for breathing activity recognition.

Sasan Sharifipour, Constantino Álvarez Casado, Le Nguyen et al.

Human Activity Recognition supports applications in healthcare, manufacturing, and human-machine interaction. LiDAR point clouds offer a privacy-preserving alternative to cameras and are robust to illumination. We propose a HAR method based on graph spectral analysis. Each LiDAR frame is mapped to a proximity graph (epsilon-graph) and the Laplacian spectrum is computed. Eigenvalues and statistics of eigenvectors form pose descriptors, and temporal statistics over sliding windows yield fixed vectors for classification with support vector machines and random forests. On the MM-Fi dataset with 40 subjects and 27 activities, under a strict subject-independent protocol, the method reaches 94.4% accuracy on a 13-class rehabilitation set and 90.3% on all 27 activities. It also surpasses the skeleton-based baselines reported for MM-Fi. The contribution is a compact and interpretable feature set derived directly from point cloud geometry that provides an accurate and efficient alternative to end-to-end deep learning.

Constantino Álvarez Casado, Sasan Sharifipour, Manuel Lage Cañellas et al.

The growing integration of smart environments and low-power computing devices, coupled with mass-market sensor technologies, is driving advancements in remote and non-contact physiological monitoring. However, deploying these systems in real-time on resource-constrained platforms introduces significant challenges related to scalability, interoperability, and performance. This paper presents a real-time remote photoplethysmography (rPPG) system optimized for low-power devices, designed to extract physiological signals, such as heart rate (HR), respiratory rate (RR), and oxygen saturation (SpO2), from facial video streams. The system is built on the Face2PPG pipeline, which processes video frames sequentially for rPPG signal extraction and analysis, while leveraging a multithreaded architecture to manage video capture, real-time processing, network communication, and graphical user interface (GUI) updates concurrently. This design ensures continuous, reliable operation at 30 frames per second (fps), with adaptive feedback through a collaborative user interface to guide optimal signal capture conditions. The network interface includes both an HTTP server for continuous video streaming and a RESTful API for on-demand vital sign retrieval. To ensure accurate performance despite the limitations of low-power devices, we use a hybrid programming model combining Functional Reactive Programming (FRP) and the Actor Model, allowing event-driven processing and efficient task parallelization. The system is evaluated under real-time constraints, demonstrating robustness while minimizing computational overhead. Our work addresses key challenges in real-time biosignal monitoring, offering practical solutions for optimizing performance in modern healthcare and human-computer interaction applications.