Bing Hu

Usman Syed, Ethan Light, Xingang Guo et al.

In this paper, we explore the capabilities of state-of-the-art large language models (LLMs) such as GPT-4, GPT-4o, Claude 3.5 Sonnet, Claude 3 Opus, Gemini 1.5 Pro, Llama 3, and Llama 3.1 in solving some selected undergraduate-level transportation engineering problems. We introduce TransportBench, a benchmark dataset that includes a sample of transportation engineering problems on a wide range of subjects in the context of planning, design, management, and control of transportation systems. This dataset is used by human experts to evaluate the capabilities of various commercial and open-sourced LLMs, especially their accuracy, consistency, and reasoning behaviors, in solving transportation engineering problems. Our comprehensive analysis uncovers the unique strengths and limitations of each LLM, e.g. our analysis shows the impressive accuracy and some unexpected inconsistent behaviors of Claude 3.5 Sonnet in solving TransportBench problems. Our study marks a thrilling first step toward harnessing artificial general intelligence for complex transportation challenges.

Xingang Guo, Darioush Keivan, Usman Syed et al.

Control system design is a crucial aspect of modern engineering with far-reaching applications across diverse sectors including aerospace, automotive systems, power grids, and robotics. Despite advances made by Large Language Models (LLMs) in various domains, their application in control system design remains limited due to the complexity and specificity of control theory. To bridge this gap, we introduce ControlAgent, a new paradigm that automates control system design via novel integration of LLM agents and control-oriented domain expertise. ControlAgent encodes expert control knowledge and emulates human iterative design processes by gradually tuning controller parameters to meet user-specified requirements for stability, performance, and robustness. ControlAgent integrates multiple collaborative LLM agents, including a central agent responsible for task distribution and task-specific agents dedicated to detailed controller design for various types of systems and requirements. ControlAgent also employs a Python computation agent that performs complex calculations and controller evaluations based on standard design information provided by task-specified LLM agents. Combined with a history and feedback module, the task-specific LLM agents iteratively refine controller parameters based on real-time feedback from prior designs. Overall, ControlAgent mimics the design processes used by (human) practicing engineers, but removes all the human efforts and can be run in a fully automated way to give end-to-end solutions for control system design with user-specified requirements. To validate ControlAgent's effectiveness, we develop ControlEval, an evaluation dataset that comprises 500 control tasks with various specific design goals. The effectiveness of ControlAgent is demonstrated via extensive comparative evaluations between LLM-based and traditional human-involved toolbox-based baselines.

Junyan Li, Bin Hu, Zhi-Hong Guan

Cross-subject variability in EEG degrades performance of current deep learning models, limiting the development of brain-computer interface (BCI). This paper proposes ISAM-MTL, which is a multi-task learning (MTL) EEG classification model based on identifiable spiking (IS) representations and associative memory (AM) networks. The proposed model treats EEG classification of each subject as an independent task and leverages cross-subject data training to facilitate feature sharing across subjects. ISAM-MTL consists of a spiking feature extractor that captures shared features across subjects and a subject-specific bidirectional associative memory network that is trained by Hebbian learning for efficient and fast within-subject EEG classification. ISAM-MTL integrates learned spiking neural representations with bidirectional associative memory for cross-subject EEG classification. The model employs label-guided variational inference to construct identifiable spike representations, enhancing classification accuracy. Experimental results on two BCI Competition datasets demonstrate that ISAM-MTL improves the average accuracy of cross-subject EEG classification while reducing performance variability among subjects. The model further exhibits the characteristics of few-shot learning and identifiable neural activity beneath EEG, enabling rapid and interpretable calibration for BCI systems.

Bing Hu, Ashish Saragadam, Anita Layton et al.

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new data challenge that slows the advancement of drug discovery AI: datasets are often collected independently from each other, often with little overlap, creating data sparsity. Data sparsity makes data curation difficult for researchers looking to answer key research questions requiring values posed across multiple datasets. We propose a novel diffusion GNN model Syngand capable of generating ligand and pharmacokinetic data end-to-end. We show and provide a methodology for sampling pharmacokinetic data for existing ligands using our Syngand model. We show the initial promising results on the efficacy of the Syngand-generated synthetic target property data on downstream regression tasks with AqSolDB, LD50, and hERG central. Using our proposed model and methodology, researchers can easily generate synthetic ligand data to help them explore research questions that require data spanning multiple datasets.