Mingya Zhang

Mingya Zhang, Liang Wang, Zhihao Chen et al.

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen rapid development in the field of image segmentation. Recently, SAM2 has garnered widespread attention in both natural image and medical image segmentation. Compared to SAM, it has significantly improved in terms of segmentation accuracy and generalization performance. We compared the foundational models based on SAM and found that their performance in semantic segmentation of pathological images was hardly satisfactory. In this paper, we propose Path-SAM2, which for the first time adapts the SAM2 model to cater to the task of pathological semantic segmentation. We integrate the largest pretrained vision encoder for histopathology (UNI) with the original SAM2 encoder, adding more pathology-based prior knowledge. Additionally, we introduce a learnable Kolmogorov-Arnold Networks (KAN) classification module to replace the manual prompt process. In three adenoma pathological datasets, Path-SAM2 has achieved state-of-the-art performance.This study demonstrates the great potential of adapting SAM2 to pathology image segmentation tasks. We plan to release the code and model weights for this paper at: https://github.com/simzhangbest/SAM2PATH

Mingya Zhang, Zhihao Chen, Yiyuan Ge et al.

In the field of medical image segmentation, models based on both CNN and Transformer have been thoroughly investigated. However, CNNs have limited modeling capabilities for long-range dependencies, making it challenging to exploit the semantic information within images fully. On the other hand, the quadratic computational complexity poses a challenge for Transformers. State Space Models (SSMs), such as Mamba, have been recognized as a promising method. They not only demonstrate superior performance in modeling long-range interactions, but also preserve a linear computational complexity. The hybrid mechanism of SSM (State Space Model) and Transformer, after meticulous design, can enhance its capability for efficient modeling of visual features. Extensive experiments have demonstrated that integrating the self-attention mechanism into the hybrid part behind the layers of Mamba's architecture can greatly improve the modeling capacity to capture long-range spatial dependencies. In this paper, leveraging the hybrid mechanism of SSM, we propose a U-shape architecture model for medical image segmentation, named Hybird Transformer vision Mamba UNet (HTM-UNet). We conduct comprehensive experiments on the ISIC17, ISIC18, CVC-300, CVC-ClinicDB, Kvasir, CVC-ColonDB, ETIS-Larib PolypDB public datasets and ZD-LCI-GIM private dataset. The results indicate that HTM-UNet exhibits competitive performance in medical image segmentation tasks. Our code is available at https://github.com/simzhangbest/HMT-Unet.

Shun Zou, Mingya Zhang, Bingjian Fan et al.

Skin lesion segmentation is a crucial method for identifying early skin cancer. In recent years, both convolutional neural network (CNN) and Transformer-based methods have been widely applied. Moreover, combining CNN and Transformer effectively integrates global and local relationships, but remains limited by the quadratic complexity of Transformer. To address this, we propose a hybrid architecture based on Mamba and CNN, called SkinMamba. It maintains linear complexity while offering powerful long-range dependency modeling and local feature extraction capabilities. Specifically, we introduce the Scale Residual State Space Block (SRSSB), which captures global contextual relationships and cross-scale information exchange at a macro level, enabling expert communication in a global state. This effectively addresses challenges in skin lesion segmentation related to varying lesion sizes and inconspicuous target areas. Additionally, to mitigate boundary blurring and information loss during model downsampling, we introduce the Frequency Boundary Guided Module (FBGM), providing sufficient boundary priors to guide precise boundary segmentation, while also using the retained information to assist the decoder in the decoding process. Finally, we conducted comparative and ablation experiments on two public lesion segmentation datasets (ISIC2017 and ISIC2018), and the results demonstrate the strong competitiveness of SkinMamba in skin lesion segmentation tasks. The code is available at https://github.com/zs1314/SkinMamba.

Mingya Zhang, Yue Yu, Limei Gu et al.

In the field of medical image segmentation, models based on both CNN and Transformer have been thoroughly investigated. However, CNNs have limited modeling capabilities for long-range dependencies, making it challenging to exploit the semantic information within images fully. On the other hand, the quadratic computational complexity poses a challenge for Transformers. Recently, State Space Models (SSMs), such as Mamba, have been recognized as a promising method. They not only demonstrate superior performance in modeling long-range interactions, but also preserve a linear computational complexity. Inspired by the Mamba architecture, We proposed Vison Mamba-UNetV2, the Visual State Space (VSS) Block is introduced to capture extensive contextual information, the Semantics and Detail Infusion (SDI) is introduced to augment the infusion of low-level and high-level features. We conduct comprehensive experiments on the ISIC17, ISIC18, CVC-300, CVC-ClinicDB, Kvasir, CVC-ColonDB and ETIS-LaribPolypDB public datasets. The results indicate that VM-UNetV2 exhibits competitive performance in medical image segmentation tasks. Our code is available at https://github.com/nobodyplayer1/VM-UNetV2.