Sonit Singh

Louisa Canepa, Sonit Singh, Arcot Sowmya

Medical visual question answering (Med-VQA) is a machine learning task that aims to create a system that can answer natural language questions based on given medical images. Although there has been rapid progress on the general VQA task, less progress has been made on Med-VQA due to the lack of large-scale annotated datasets. In this paper, we present domain-specific pre-training strategies, including a novel contrastive learning pretraining method, to mitigate the problem of small datasets for the Med-VQA task. We find that the model benefits from components that use fewer parameters. We also evaluate and discuss the model's visual reasoning using evidence verification techniques. Our proposed model obtained an accuracy of 60% on the VQA-Med 2019 test set, giving comparable results to other state-of-the-art Med-VQA models.

Shisheng Zhang, Ramtin Gharleghi, Sonit Singh et al.

Coronary artery diseases are among the leading causes of mortality worldwide. Timely and accurate diagnosis, facilitated by precise coronary artery segmentation, is pivotal in changing patient outcomes. In the realm of biomedical imaging, convolutional neural networks, especially the U-Net architecture, have revolutionised segmentation processes. However, one of the primary challenges remains the lack of benchmarking datasets specific to coronary arteries. However through the use of the recently published public dataset ASOCA, the potential of deep learning for accurate coronary segmentation can be improved. This paper delves deep into examining the performance of 25 distinct encoder-decoder combinations. Through analysis of the 40 cases provided to ASOCA participants, it is revealed that the EfficientNet-LinkNet combination, serving as encoder and decoder, stands out. It achieves a Dice coefficient of 0.882 and a 95th percentile Hausdorff distance of 4.753. These findings not only underscore the superiority of our model in comparison to those presented at the MICCAI 2020 challenge but also set the stage for future advancements in coronary artery segmentation, opening doors to enhanced diagnostic and treatment strategies.

Md Akizur Rahman, Sonit Singh, Kuruparan Shanmugalingam et al.

Segmentation of the sigmoid colon is a crucial aspect of treating diverticulitis. It enables accurate identification and localisation of inflammation, which in turn helps healthcare professionals make informed decisions about the most appropriate treatment options. This research presents a novel deep learning architecture for segmenting the sigmoid colon from Computed Tomography (CT) images using a modified 3D U-Net architecture. Several variations of the 3D U-Net model with modified hyper-parameters were examined in this study. Pyramid pooling (PyP) and channel-spatial Squeeze and Excitation (csSE) were also used to improve the model performance. The networks were trained using manually annotated sigmoid colon. A five-fold cross-validation procedure was used on a test dataset to evaluate the network's performance. As indicated by the maximum Dice similarity coefficient (DSC) of 56.92+/-1.42%, the application of PyP and csSE techniques improves segmentation precision. We explored ensemble methods including averaging, weighted averaging, majority voting, and max ensemble. The results show that average and majority voting approaches with a threshold value of 0.5 and consistent weight distribution among the top three models produced comparable and optimal results with DSC of 88.11+/-3.52%. The results indicate that the application of a modified 3D U-Net architecture is effective for segmenting the sigmoid colon in Computed Tomography (CT) images. In addition, the study highlights the potential benefits of integrating ensemble methods to improve segmentation precision.

Lachlan Nguyen, Aidan Cousins, Arcot Sowmya et al.

Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive semiautomatic analysis of cardiac computed tomography by radiologists and trained radiographers. The purpose of this study is to develop a deep learning convolutional neural networks (CNN) model to classify the calcium score in cardiac, non-contrast computed tomography images into one of six clinical categories. A total of 68 patient scans were retrospectively obtained together with their respective reported semiautomatic calcium score using an ECG-gated GE Discovery 570 Cardiac SPECT/CT camera. The dataset was divided into training, validation and test sets. Using the semiautomatic CAC score as the reference label, the model demonstrated high performance on a six-class CAC scoring categorisation task. Of the scans analysed, the model misclassified 32 cases, tending towards overestimating the CAC in 26 out of 32 misclassifications. Overall, the model showed high agreement (Cohen's kappa of 0.962), an overall accuracy of 96.5% and high generalisability. The results suggest that the model outputs were accurate and consistent with current semiautomatic practice, with good generalisability to test data. The model demonstrates the viability of a CNN model to stratify the calcium score into an expanded set of six clinical categories.

Neo Wang, Sonit Singh

The course forums are increasingly significant and play vital role in facilitating student discussions and answering their questions related to the course. It provides a platform for students to post their questions related to the content and admin issues related to the course. However, there are several challenges due to the increase in the number of students enrolled in the course. The primary challenge is that students' queries cannot be responded immediately and the instructors have to face lots of repetitive questions. To mitigate these issues, we propose a question answering system based on large language model with retrieval augmented generation (RAG) method. This work focuses on designing a question answering system with open source Large Language Model (LLM) and fine-tuning it on the relevant course dataset. To further improve the performance, we use a local knowledge base and applied RAG method to retrieve relevant documents relevant to students' queries, where the local knowledge base contains all the course content. To mitigate the hallucination of LLMs, We also integrate it with multi chain-of-thought reasoning to overcome the challenge of hallucination in LLMs. In this work, we experiment fine-tuned LLM with RAG method on the HotpotQA dataset. The experimental results demonstrate that the fine-tuned LLM with RAG method has a strong performance on question answering task.

Dylan Saeed, Ramtin Gharleghi, Susann Bier et al.

Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest X-rays (CXRs) are inexpensive but lack reliable ground truth labels, constraining deep learning development. Digitally reconstructed radiographs (DRRs) offer a scalable alternative by projecting CT volumes into CXR-like images while inheriting precise labels. In this work, we provide the first systematic evaluation of DRRs as a surrogate training domain for CAC detection. Using 667 CT scans from the COCA dataset, we generate synthetic DRRs and assess model capacity, super-resolution fidelity enhancement, preprocessing, and training strategies. Lightweight CNNs trained from scratch outperform large pretrained networks; pairing super-resolution with contrast enhancement yields significant gains; and curriculum learning stabilises training under weak supervision. Our best configuration achieves a mean AUC of 0.754, comparable to or exceeding prior CXR-based studies. These results establish DRRs as a scalable, label-rich foundation for CAC detection, while laying the foundation for future transfer learning and domain adaptation to real CXRs.

Sonit Singh

Recent developments in the field of Natural Language Processing, especially language models such as the transformer have brought state-of-the-art results in language understanding and language generation. In this work, we investigate the use of the transformer model for radiology report generation from chest X-rays. We also highlight limitations in evaluating radiology report generation using only the standard language generation metrics. We then applied a transformer based radiology report generation architecture, and also compare the performance of a transformer based decoder with the recurrence based decoder. Experiments were performed using the IU-CXR dataset, showing superior results to its LSTM counterpart and being significantly faster. Finally, we identify the need of evaluating radiology report generation system using both language generation metrics and classification metrics, which helps to provide robust measure of generated reports in terms of their coherence and diagnostic value.

Dhruv Gulwani, Basem Suleiman, Aditya Joshi et al.

Project-based learning improves student engagement and learning outcomes, yet allocating students to appropriately challenging projects while forming cognitively diverse teams remains difficult at scale. Traditional allocation methods (manual spreadsheets, preference surveys) can't construct the cognitively diverse teams that that collaborate cognitively. This mismatch perpetuates equity issues: high-performing students self-select visible projects while under-represented students face reduced access to opportunity. We propose TeamUp, a lightweight, embedding-based team-forming system designed to improve learning outcomes and equity in large-scale project-based courses. TeamUp uses semantic embeddings from pretrained language models to match students to projects aligned with their skill level. The system employs a hybrid ranking algorithm combining cosine similarity with pedagogical constraints (difficulty alignment, domain preferences, and demand balancing) to generate personalised and transparent recommendations. Beyond individual matching, TeamUp constructs cognitively diverse teams by modelling skill complementarity through embedding variance, ensuring teams possess well-distributed capabilities rather than homogeneous strengths. We evaluated TeamUp through a virtual experiment using 250 student profiles and 60 project descriptions. Results show: (1) substantially higher match quality (mean cosine similarity of 0.74 vs. 0.43); (2) better difficulty alignment (83% placed within one level vs. 34%); (3) more diverse teams (82% covering three or more technical areas vs. 41%); and (4) sub-second recommendation latency at operational costs under $0.10 per student.

Ruban Goyal, Rohitash Chandra, Sonit Singh

Personal attacks have become a notable feature of U.S. presidential debates and play an important role in shaping public perception during elections. Detecting such attacks can improve transparency in political discourse and provide insights for journalists, analysts and the public. Advances in deep learning and transformer-based models, particularly BERT and large language models (LLMs) have created new opportunities for automated detection of harmful language. Motivated by these developments, we present a framework for analysing personal attacks in U.S. presidential debates. Our work involves manual annotation of debate transcripts across the 2016, 2020 and 2024 election cycles, followed by statistical and language-model based analysis. We investigate the potential of fine-tuned transformer models alongside general-purpose LLMs to detect personal attacks in formal political speech. This study demonstrates how task-specific adaptation of modern language models can contribute to a deeper understanding of political communication.

Ramya Kumar, Dhruv Gulwani, Sonit Singh

This paper explores the automatic classification of exam questions and learning outcomes according to Bloom's Taxonomy. A small dataset of 600 sentences labeled with six cognitive categories - Knowledge, Comprehension, Application, Analysis, Synthesis, and Evaluation - was processed using traditional machine learning (ML) models (Naive Bayes, Logistic Regression, Support Vector Machines), recurrent neural network architectures (LSTM, BiLSTM, GRU, BiGRU), transformer-based models (BERT and RoBERTa), and large language models (OpenAI, Gemini, Ollama, Anthropic). Each model was evaluated under different preprocessing and augmentation strategies (for example, synonym replacement, word embeddings, etc.). Among traditional ML approaches, Support Vector Machines (SVM) with data augmentation achieved the best overall performance, reaching 94 percent accuracy, recall, and F1 scores with minimal overfitting. In contrast, the RNN models and BERT suffered from severe overfitting, while RoBERTa initially overcame it but began to show signs as training progressed. Finally, zero-shot evaluations of large language models (LLMs) indicated that OpenAI and Gemini performed best among the tested LLMs, achieving approximately 0.72-0.73 accuracy and comparable F1 scores. These findings highlight the challenges of training complex deep models on limited data and underscore the value of careful data augmentation and simpler algorithms (such as augmented SVM) for Bloom's Taxonomy classification.

Rahul Soni, Basem Suleiman, Sonit Singh

This paper aims to address the challenge of selecting relevant courses for students by proposing the design and development of a course recommendation system. The course recommendation system utilises a combination of data analytics techniques and machine learning algorithms to recommend courses that align with current industry trends and requirements. In order to provide customised suggestions, the study entails the design and implementation of an extensive algorithmic framework that combines machine learning methods, user preferences, and academic criteria. The system employs data mining and collaborative filtering techniques to examine past courses and individual career goals in order to provide course recommendations. Moreover, to improve the accessibility and usefulness of the recommendation system, special attention is given to the development of an easy-to-use front-end interface. The front-end design prioritises visual clarity, interaction, and simplicity through iterative prototyping and user input revisions, guaranteeing a smooth and captivating user experience. We refined and optimised the proposed system by incorporating user feedback, ensuring that it effectively meets the needs and preferences of its target users. The proposed course recommendation system could be a useful tool for students, instructors, and career advisers to use in promoting lifelong learning and professional progression as it fills the gap between university learning and industry expectations. We hope that the proposed course recommendation system will help university students in making data-drive and industry-informed course decisions, in turn, improving graduate outcomes for the university sector.

Sonit Singh

Medical imaging has been used for diagnosis of various conditions, making it one of the most powerful resources for effective patient care. Due to widespread availability, low cost, and low radiation, chest X-ray is one of the most sought after radiology examination for the diagnosis of various thoracic diseases. Due to advancements in medical imaging technologies and increasing patient load, current radiology workflow faces various challenges including increasing backlogs, working long hours, and increase in diagnostic errors. An automated computer-aided diagnosis system that can interpret chest X-rays to augment radiologists by providing actionable insights has potential to provide second opinion to radiologists, highlight relevant regions in the image, in turn expediting clinical workflow, reducing diagnostic errors, and improving patient care. In this study, we applied a novel architecture augmenting the DenseNet121 Convolutional Neural Network (CNN) with multi-head self-attention mechanism using transformer, namely SA-DenseNet121, that can identify multiple thoracic diseases in chest X-rays. We conducted experiments on four of the largest chest X-ray datasets, namely, ChestX-ray14, CheXpert, MIMIC-CXR-JPG, and IU-CXR. Experimental results in terms of area under the receiver operating characteristics (AUC-ROC) shows that augmenting CNN with self-attention has potential in diagnosing different thoracic diseases from chest X-rays. The proposed methodology has the potential to support the reading workflow, improve efficiency, and reduce diagnostic errors.

Sonit Singh

Recent advances in deep learning have enabled researchers to explore tasks at the intersection of computer vision and natural language processing, such as image captioning, visual question answering, visual dialogue, and visual language navigation. Taking inspiration from image captioning, the task of radiology report generation aims at automatically generating radiology reports by having a comprehensive understanding of medical images. However, automatically generating radiology reports from medical images is a challenging task due to the complexity, diversity, and nature of medical images. In this paper, we outline the design of a robust radiology report generation system by integrating different modules and highlighting best practices drawing upon lessons from our past work and also from relevant studies in the literature. We also discuss the impact of integrating different components to form a single integrated system. We believe that these best practices, when implemented, could improve automatic radiology report generation, augment radiologists in decision making, and expedite diagnostic workflow, in turn improve healthcare and save human lives.

Sonit Singh

The novel coronavirus (COVID-19), a highly infectious respiratory disease caused by the SARS-CoV-2 has emerged as an unprecedented healthcare crisis. The pandemic had a devastating impact on the health, well-being, and economy of the global population. Early screening and diagnosis of symptomatic patients plays crucial role in isolation of patient to help stop community transmission as well as providing early treatment helping in reducing the mortality rate. Although, the RT-PCR test is the gold standard for COVID-19 testing, it is a manual, laborious, time consuming, uncomfortable, and invasive process. Due to its accessibility, availability, lower-cost, ease of sanitisation, and portable setup, chest X-Ray imaging can serve as an effective screening and diagnostic tool. In this study, we first highlight limitations of existing datasets and studies in terms of data quality, data imbalance, and evaluation strategy. Second, we curated a large-scale COVID-19 chest X-ray dataset from many publicly available COVID-19 imaging databases and proposed a pre-processing pipeline to improve quality of the dataset. We proposed CoVScreen, an CNN architecture to train and test the curated dataset. The experimental results applying different classification scenarios on the curated dataset in terms of various evaluation metrics demonstrate the effectiveness of proposed methodology in the screening of COVID-19 infection.

Sonit Singh, Gordon Stevenson, Brendan Mein et al.

Purpose: Ultrasound is the most commonly used medical imaging modality for diagnosis and screening in clinical practice. Due to its safety profile, noninvasive nature and portability, ultrasound is the primary imaging modality for fetal assessment in pregnancy. Current ultrasound processing methods are either manual or semi-automatic and are therefore laborious, time-consuming and prone to errors, and automation would go a long way in addressing these challenges. Automated identification of placental changes at earlier gestation could facilitate potential therapies for conditions such as fetal growth restriction and pre-eclampsia that are currently detected only at late gestational age, potentially preventing perinatal morbidity and mortality. Methods: We propose an automatic three-dimensional multi-modal (B-mode and power Doppler) ultrasound segmentation of the human placenta using deep learning combined with different fusion strategies.We collected data containing Bmode and power Doppler ultrasound scans for 400 studies. Results: We evaluated different fusion strategies and state-of-the-art image segmentation networks for placenta segmentation based on standard overlap- and boundary-based metrics. We found that multimodal information in the form of B-mode and power Doppler scans outperform any single modality. Furthermore, we found that B-mode and power Doppler input scans fused at the data level provide the best results with a mean Dice Similarity Coefficient (DSC) of 0.849. Conclusion: We conclude that the multi-modal approach of combining B-mode and power Doppler scans is effective in segmenting the placenta from 3D ultrasound scans in a fully automated manner and is robust to quality variation of the datasets.

Sammriddh Gupta, Sonit Singh, Aditya Joshi et al.

Language educators strive to create a rich experience for learners, while they may be restricted in the extend of feedback and practice they can provide. We present the design and development of LangLingual, a conversational agent built using the LangChain framework and powered by Large Language Models. The system is specifically designed to provide real-time, grammar-focused feedback, generate context-aware language exercises and track learner proficiency over time. The paper discusses the architecture, implementation and evaluation of LangLingual in detail. The results indicate strong usability, positive learning outcomes and encouraging learner engagement.

Shisheng Zhang, Ramtin Gharleghi, Sonit Singh et al.

Coronary artery disease (CAD) remains the leading cause of death globally, with computed tomography coronary angiography (CTCA) serving as a key diagnostic tool. However, coronary arterial analysis using CTCA, such as identifying artery-specific features from computational modelling, is labour-intensive and time-consuming. Automated anatomical labelling of coronary arteries offers a potential solution, yet the inherent anatomical variability of coronary trees presents a significant challenge. Traditional knowledge-based labelling methods fall short in leveraging data-driven insights, while recent deep-learning approaches often demand substantial computational resources and overlook critical clinical knowledge. To address these limitations, we propose a lightweight method that integrates anatomical knowledge with rule-based topology constraints for effective coronary artery labelling. Our approach achieves state-of-the-art performance on benchmark datasets, providing a promising alternative for automated coronary artery labelling.

Sonit Singh

With rise of digital age, there is an explosion of information in the form of news, articles, social media, and so on. Much of this data lies in unstructured form and manually managing and effectively making use of it is tedious, boring and labor intensive. This explosion of information and need for more sophisticated and efficient information handling tools gives rise to Information Extraction(IE) and Information Retrieval(IR) technology. Information Extraction systems takes natural language text as input and produces structured information specified by certain criteria, that is relevant to a particular application. Various sub-tasks of IE such as Named Entity Recognition, Coreference Resolution, Named Entity Linking, Relation Extraction, Knowledge Base reasoning forms the building blocks of various high end Natural Language Processing (NLP) tasks such as Machine Translation, Question-Answering System, Natural Language Understanding, Text Summarization and Digital Assistants like Siri, Cortana and Google Now. This paper introduces Information Extraction technology, its various sub-tasks, highlights state-of-the-art research in various IE subtasks, current challenges and future research directions.