Yinsong Xu

Yinsong Xu, Wei Jing, Liuxin Zhang et al.

Understanding long-form egocentric videos remains challenging for multimodal large language models (MLLMs) due to limited context length and insufficient grounding of fine-grained visual details. The recently proposed HD-EPIC benchmark highlights these limitations: even strong long-context models achieve relatively low performance across diverse video question answering tasks. In this paper, we propose a unified framework that decouples long-video reasoning into two complementary forms of evidence: semantic evidence and visual evidence. Semantic evidence captures global procedural structure through a coarse-to-fine extraction pipeline, while object-centric visual evidence preserves fine-grained grounding through bounding boxes and visual embeddings. During inference, we formulate reasoning as a query-conditioned evidence retrieval and integration process, dynamically selecting relevant information from both sources. Our approach achieves competitive performance in the HD-EPIC-VQA Challenge across multiple task categories. More broadly, our results demonstrate that explicitly structuring, retrieving, and integrating semantic and visual evidence is critical for effective long-video understanding with MLLMs.

Yinsong Xu, Zhuqing Jiang, Aidong Men et al.

Existing domain adaptation methods assume that domain discrepancies are caused by a few discrete attributes and variations, e.g., art, real, painting, quickdraw, etc. We argue that this is not realistic as it is implausible to define the real-world datasets using a few discrete attributes. Therefore, we propose to investigate a new problem namely the Continuous Domain Adaptation (CDA) through the lens where infinite domains are formed by continuously varying attributes. Leveraging knowledge of two labeled source domains and several observed unlabeled target domains data, the objective of CDA is to learn a generalized model for whole data distribution with the continuous attribute. Besides the contributions of formulating a new problem, we also propose a novel approach as a strong CDA baseline. To be specific, firstly we propose a novel alternating training strategy to reduce discrepancies among multiple domains meanwhile generalize to unseen target domains. Secondly, we propose a continuity constraint when estimating the cross-domain divergence measurement. Finally, to decouple the discrepancy from the mini-batch size, we design a domain-specific queue to maintain the global view of the source domain that further boosts the adaptation performances. Our method is proven to achieve the state-of-the-art in CDA problem using extensive experiments. The code is available at https://github.com/SPIresearch/CDA.

Yinsong Xu, Yipei Wang, Ziyi Shen et al.

The Gleason groups serve as the primary histological grading system for prostate cancer, providing crucial insights into the cancer's potential for growth and metastasis. In clinical practice, pathologists determine the Gleason groups based on specimens obtained from ultrasound-guided biopsies. In this study, we investigate the feasibility of directly estimating the Gleason groups from MRI scans to reduce otherwise required biopsies. We identify two characteristics of this task, ordinality and the resulting dependent yet unknown variances between Gleason groups. In addition to the inter- / intra- observer variability in a multi-step Gleason scoring process based on the interpretation of Gleason patterns, our MR-based prediction is also subject to specimen sampling variance and, to a lesser degree, varying MR imaging protocols. To address this challenge, we propose a novel Poisson ordinal network (PON). PONs model the prediction using a Poisson distribution and leverages Poisson encoding and Poisson focal loss to capture a learnable dependency between ordinal classes (here, Gleason groups), rather than relying solely on the numerical ground-truth (e.g. Gleason Groups 1-5 or Gleason Scores 6-10). To improve this modelling efficacy, PONs also employ contrastive learning with a memory bank to regularise intra-class variance, decoupling the memory requirement of contrast learning from the batch size. Experimental results based on the images labelled by saturation biopsies from 265 prior-biopsy-blind patients, across two tasks demonstrate the superiority and effectiveness of our proposed method.

Yipei Wang, Yinsong Xu, Weixi Yi et al.

Many diagnostic and therapeutic clinical tasks for prostate cancer increasingly rely on multi-parametric MRI. Automating these tasks is challenging because they necessitate expert interpretations, which are difficult to scale to capitalise on modern deep learning. Although modern automated systems achieve expert-level performance in isolated tasks, their general clinical utility remains limited by the requirement of large task-specific labelled datasets. In this paper, we present ProFound, a domain-specialised vision foundation model for volumetric prostate mpMRI. ProFound is pre-trained using several variants of self-supervised approaches on a diverse, multi-institutional collection of 5,000 patients, with a total of over 22,000 unique 3D MRI volumes (over 1,800,000 2D image slices). We conducted a systematic evaluation of ProFound across a broad spectrum of $11$ downstream clinical tasks on over 3,000 independent patients, including prostate cancer detection, Gleason grading, lesion localisation, gland volume estimation, zonal and surrounding structure segmentation. Experimental results demonstrate that finetuned ProFound consistently outperforms or remains competitive with state-of-the-art specialised models and existing medical vision foundation models trained/finetuned on the same data.

Yinsong Xu, Aidong Men, Yang Liu et al.

In deep learning, initializing models with pre-trained weights has become the de facto practice for various downstream tasks. Many unsupervised domain adaptation (UDA) methods typically adopt a backbone pre-trained on ImageNet, and focus on reducing the source-target domain discrepancy. However, the impact of pre-training on adaptation received little attention. In this study, we delve into UDA from the novel perspective of pre-training. We first demonstrate the impact of pre-training by analyzing the dynamic distribution discrepancies between pre-training data domain and the source/ target domain during adaptation. Then, we reveal that the target error also stems from the pre-training in the following two factors: 1) empirically, target error arises from the gradually degenerative pre-trained knowledge during adaptation; 2) theoretically, the error bound depends on difference between the gradient of loss function, \ie, on the target domain and pre-training data domain. To address these two issues, we redefine UDA as a three-domain problem, \ie, source domain, target domain, and pre-training data domain; then we propose a novel framework, named TriDA. We maintain the pre-trained knowledge and improve the error bound by incorporating pre-training data into adaptation for both vanilla UDA and source-free UDA scenarios. For efficiency, we introduce a selection strategy for pre-training data, and offer a solution with synthesized images when pre-training data is unavailable during adaptation. Notably, TriDA is effective even with a small amount of pre-training or synthesized images, and seamlessly complements the two scenario UDA methods, demonstrating state-of-the-art performance across multiple benchmarks. We hope our work provides new insights for better understanding and application of domain adaptation.

Yinsong Xu, Jiaqi Tang, Aidong Men et al.

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention and the domain gap between natural and medical images poses significant obstacles. This paper introduces a novel training-free evidential prompt generation method named EviPrompt to overcome these issues. The proposed method, built on the inherent similarities within medical images, requires only a single reference image-annotation pair, making it a training-free solution that significantly reduces the need for extensive labeling and computational resources. First, to automatically generate prompts for SAM in medical images, we introduce an evidential method based on uncertainty estimation without the interaction of clinical experts. Then, we incorporate the human prior into the prompts, which is vital for alleviating the domain gap between natural and medical images and enhancing the applicability and usefulness of SAM in medical scenarios. EviPrompt represents an efficient and robust approach to medical image segmentation, with evaluations across a broad range of tasks and modalities confirming its efficacy.

Jiaqi Tang, Yinsong Xu, Yang Liu et al.

Multi-modal fusion often suffers from modality competition during joint training, where one modality dominates the learning process, leaving others under-optimized. Overlooking the critical impact of the model's initial state, most existing methods address this issue during the joint learning stage. In this study, we introduce a two-stage training framework to shape the initial states through unimodal training before the joint training. First, we propose the concept of Effective Competitive Strength (ECS) to quantify a modality's competitive strength. Our theoretical analysis further reveals that properly shaping the initial ECS by unimodal training achieves a provably tighter error bound. However, ECS is computationally intractable in deep neural networks. To bridge this gap, we develop a framework comprising two core components: a fine-grained computable diagnostic metric and an asynchronous training controller. For the metric, we first prove that mutual information(MI) is a principled proxy for ECS. Considering MI is induced by per-modality marginals and thus treats each modality in isolation, we further propose FastPID, a computationally efficient and differentiable solver for partial information decomposition, which decomposes the joint distribution's information into fine-grained measurements: modality-specific uniqueness, redundancy, and synergy. Guided by these measurements, our asynchronous controller dynamically balances modalities by monitoring uniqueness and locates the ideal initial state to start joint training by tracking peak synergy. Experiments on diverse benchmarks demonstrate that our method achieves state-of-the-art performance. Our work establishes that shaping the pre-fusion models' initial state is a powerful strategy that eases competition before it starts, reliably unlocking synergistic multi-modal fusion.

Jiaqi Tang, Yinsong Xu, Qingchao Chen

Object classification models utilizing point cloud data are fundamental for 3D media understanding, yet they often struggle with unseen or out-of-distribution (OOD) scenarios. Existing point cloud unsupervised domain adaptation (UDA) methods typically employ a multi-task learning (MTL) framework that combines primary classification tasks with auxiliary self-supervision tasks to bridge the gap between cross-domain feature distributions. However, our further experiments demonstrate that not all gradients from self-supervision tasks are beneficial and some may negatively impact the classification performance. In this paper, we propose a novel solution, termed Saliency Map-based Data Sampling Block (SM-DSB), to mitigate these gradient conflicts. Specifically, our method designs a new scoring mechanism based on the skewness of 3D saliency maps to estimate gradient conflicts without requiring target labels. Leveraging this, we develop a sample selection strategy that dynamically filters out samples whose self-supervision gradients are not beneficial for the classification. Our approach is scalable, introducing modest computational overhead, and can be integrated into all the point cloud UDA MTL frameworks. Extensive evaluations demonstrate that our method outperforms state-of-the-art approaches. In addition, we provide a new perspective on understanding the UDA problem through back-propagation analysis.

Yinsong Xu, Zheng Yuan

Inspired by Hosoyamada et al.'s work [14], we propose a new quantum meet-in-the-middle (QMITM) attack on $r$-round ($r \ge 7$) Feistel construction to reduce the time complexity. Similar to Hosoyamada et al.'s work, our attack on 7-round Feistel is also based on Guo et al.'s classical meet-in-the-middle (MITM) attack [13]. The classic MITM attack consumes a lot of time mainly in three aspects: construct the lookup table, query data and find a match. Therefore, parallel Grover search processors are used to reduce the time of constructing the lookup table. And we adjust the truncated differentials of the 5-round distinguisher proposed by Guo et al. to balance the complexities between constructing the lookup table and querying data. Finally, we introduce a quantum claw finding algorithm to find a match for reducing time. The subkeys can be recovered by this match. Furthermore, for $r$-round ($r > 7$) Feistel construction, we treat the above attack on the first 7 rounds as an inner loop and use Grover's algorithm to search the last $r-7$ rounds of subkeys as an outer loop. In summary, the total time complexity of our attack on $r$-round ($r \ge 7$) is only $O(2^{2n/3+(r-7)n/4})$ less than classical and quantum attacks. Moreover, our attack belongs to Q1 model and is more practical than other quantum attacks.