Qingchao Chen

Ting Lei, Fabian Caba, Qingchao Chen et al.

Human Object Interaction (HOI) detection aims to localize and infer the relationships between a human and an object. Arguably, training supervised models for this task from scratch presents challenges due to the performance drop over rare classes and the high computational cost and time required to handle long-tailed distributions of HOIs in complex HOI scenes in realistic settings. This observation motivates us to design an HOI detector that can be trained even with long-tailed labeled data and can leverage existing knowledge from pre-trained models. Inspired by the powerful generalization ability of the large Vision-Language Models (VLM) on classification and retrieval tasks, we propose an efficient Adaptive HOI Detector with Concept-guided Memory (ADA-CM). ADA-CM has two operating modes. The first mode makes it tunable without learning new parameters in a training-free paradigm. Its second mode incorporates an instance-aware adapter mechanism that can further efficiently boost performance if updating a lightweight set of parameters can be afforded. Our proposed method achieves competitive results with state-of-the-art on the HICO-DET and V-COCO datasets with much less training time. Code can be found at https://github.com/ltttpku/ADA-CM.

Jiangbo Pei, Zhuqing Jiang, Aidong Men et al.

Source-free unsupervised domain adaptation (SFUDA) aims to learn a target domain model using unlabeled target data and the knowledge of a well-trained source domain model. Most previous SFUDA works focus on inferring semantics of target data based on the source knowledge. Without measuring the transferability of the source knowledge, these methods insufficiently exploit the source knowledge, and fail to identify the reliability of the inferred target semantics. However, existing transferability measurements require either source data or target labels, which are infeasible in SFUDA. To this end, firstly, we propose a novel Uncertainty-induced Transferability Representation (UTR), which leverages uncertainty as the tool to analyse the channel-wise transferability of the source encoder in the absence of the source data and target labels. The domain-level UTR unravels how transferable the encoder channels are to the target domain and the instance-level UTR characterizes the reliability of the inferred target semantics. Secondly, based on the UTR, we propose a novel Calibrated Adaption Framework (CAF) for SFUDA, including i)the source knowledge calibration module that guides the target model to learn the transferable source knowledge and discard the non-transferable one, and ii)the target semantics calibration module that calibrates the unreliable semantics. With the help of the calibrated source knowledge and the target semantics, the model adapts to the target domain safely and ultimately better. We verified the effectiveness of our method using experimental results and demonstrated that the proposed method achieves state-of-the-art performances on the three SFUDA benchmarks. Code is available at https://github.com/SPIresearch/UTR.

Yinsong Xu, Zhuqing Jiang, Aidong Men et al.

Existing domain adaptation methods assume that domain discrepancies are caused by a few discrete attributes and variations, e.g., art, real, painting, quickdraw, etc. We argue that this is not realistic as it is implausible to define the real-world datasets using a few discrete attributes. Therefore, we propose to investigate a new problem namely the Continuous Domain Adaptation (CDA) through the lens where infinite domains are formed by continuously varying attributes. Leveraging knowledge of two labeled source domains and several observed unlabeled target domains data, the objective of CDA is to learn a generalized model for whole data distribution with the continuous attribute. Besides the contributions of formulating a new problem, we also propose a novel approach as a strong CDA baseline. To be specific, firstly we propose a novel alternating training strategy to reduce discrepancies among multiple domains meanwhile generalize to unseen target domains. Secondly, we propose a continuity constraint when estimating the cross-domain divergence measurement. Finally, to decouple the discrepancy from the mini-batch size, we design a domain-specific queue to maintain the global view of the source domain that further boosts the adaptation performances. Our method is proven to achieve the state-of-the-art in CDA problem using extensive experiments. The code is available at https://github.com/SPIresearch/CDA.

Minghang Zheng, Jiahua Zhang, Qingchao Chen et al.

Visual grounding aims to localize the object referred to in an image based on a natural language query. Although progress has been made recently, accurately localizing target objects within multiple-instance distractions (multiple objects of the same category as the target) remains a significant challenge. Existing methods demonstrate a significant performance drop when there are multiple distractions in an image, indicating an insufficient understanding of the fine-grained semantics and spatial relationships between objects. In this paper, we propose a novel approach, the Relation and Semantic-sensitive Visual Grounding (ResVG) model, to address this issue. Firstly, we enhance the model's understanding of fine-grained semantics by injecting semantic prior information derived from text queries into the model. This is achieved by leveraging text-to-image generation models to produce images representing the semantic attributes of target objects described in queries. Secondly, we tackle the lack of training samples with multiple distractions by introducing a relation-sensitive data augmentation method. This method generates additional training data by synthesizing images containing multiple objects of the same category and pseudo queries based on their spatial relationships. The proposed ReSVG model significantly improves the model's ability to comprehend both object semantics and spatial relations, leading to enhanced performance in visual grounding tasks, particularly in scenarios with multiple-instance distractions. We conduct extensive experiments to validate the effectiveness of our methods on five datasets. Code is available at https://github.com/minghangz/ResVG.

Jianan Han, Shaoxing Zhang, Aidong Men et al.

It is inevitably crucial to classify sleep stage for the diagnosis of various diseases. However, existing automated diagnosis methods mostly adopt the "gold-standard" lectroencephalogram (EEG) or other uni-modal sensing signal of the PolySomnoGraphy (PSG) machine in hospital, that are expensive, importable and therefore unsuitable for point-of-care monitoring at home. To enable the sleep stage monitoring at home, in this paper, we analyze the relationship between infrared videos and the EEG signal and propose a new task: to classify the sleep stage using infrared videos by distilling useful knowledge from EEG signals to the visual ones. To establish a solid cross-modal benchmark for this application, we develop a new dataset termed as Seeing your Sleep Stage via Infrared Video and EEG ($S^3VE$). $S^3VE$ is a large-scale dataset including synchronized infrared video and EEG signal for sleep stage classification, including 105 subjects and 154,573 video clips that is more than 1100 hours long. Our contributions are not limited to datasets but also about a novel cross-modal distillation baseline model namely the structure-aware contrastive distillation (SACD) to distill the EEG knowledge to infrared video features. The SACD achieved the state-of-the-art performances on both our $S^3VE$ and the existing cross-modal distillation benchmark. Both the benchmark and the baseline methods will be released to the community. We expect to raise more attentions and promote more developments in the sleep stage classification and more importantly the cross-modal distillation from clinical signal/media to the conventional media.

Minghang Zheng, Xinhao Cai, Qingchao Chen et al.

Video temporal grounding aims to identify video segments within untrimmed videos that are most relevant to a given natural language query. Existing video temporal localization models rely on specific datasets for training and have high data collection costs, but they exhibit poor generalization capability under the across-dataset and out-of-distribution (OOD) settings. In this paper, we propose a Training-Free Video Temporal Grounding (TFVTG) approach that leverages the ability of pre-trained large models. A naive baseline is to enumerate proposals in the video and use the pre-trained visual language models (VLMs) to select the best proposal according to the vision-language alignment. However, most existing VLMs are trained on image-text pairs or trimmed video clip-text pairs, making it struggle to (1) grasp the relationship and distinguish the temporal boundaries of multiple events within the same video; (2) comprehend and be sensitive to the dynamic transition of events (the transition from one event to another) in the video. To address these issues, we propose leveraging large language models (LLMs) to analyze multiple sub-events contained in the query text and analyze the temporal order and relationships between these events. Secondly, we split a sub-event into dynamic transition and static status parts and propose the dynamic and static scoring functions using VLMs to better evaluate the relevance between the event and the description. Finally, for each sub-event description, we use VLMs to locate the top-k proposals and leverage the order and relationships between sub-events provided by LLMs to filter and integrate these proposals. Our method achieves the best performance on zero-shot video temporal grounding on Charades-STA and ActivityNet Captions datasets without any training and demonstrates better generalization capabilities in cross-dataset and OOD settings.

Yinsong Xu, Yipei Wang, Ziyi Shen et al.

The Gleason groups serve as the primary histological grading system for prostate cancer, providing crucial insights into the cancer's potential for growth and metastasis. In clinical practice, pathologists determine the Gleason groups based on specimens obtained from ultrasound-guided biopsies. In this study, we investigate the feasibility of directly estimating the Gleason groups from MRI scans to reduce otherwise required biopsies. We identify two characteristics of this task, ordinality and the resulting dependent yet unknown variances between Gleason groups. In addition to the inter- / intra- observer variability in a multi-step Gleason scoring process based on the interpretation of Gleason patterns, our MR-based prediction is also subject to specimen sampling variance and, to a lesser degree, varying MR imaging protocols. To address this challenge, we propose a novel Poisson ordinal network (PON). PONs model the prediction using a Poisson distribution and leverages Poisson encoding and Poisson focal loss to capture a learnable dependency between ordinal classes (here, Gleason groups), rather than relying solely on the numerical ground-truth (e.g. Gleason Groups 1-5 or Gleason Scores 6-10). To improve this modelling efficacy, PONs also employ contrastive learning with a memory bank to regularise intra-class variance, decoupling the memory requirement of contrast learning from the batch size. Experimental results based on the images labelled by saturation biopsies from 265 prior-biopsy-blind patients, across two tasks demonstrate the superiority and effectiveness of our proposed method.

Dejie Yang, Zhu Xu, Wentao Mo et al.

3D Vision-Language Pre-training (3D-VLP) aims to provide a pre-train model which can bridge 3D scenes with natural language, which is an important technique for embodied intelligence. However, current 3D-VLP datasets are hindered by limited scene-level diversity and insufficient fine-grained annotations (only 1.2K scenes and 280K textual annotations in ScanScribe), primarily due to the labor-intensive of collecting and annotating 3D scenes. To overcome these obstacles, we construct SynVL3D, a comprehensive synthetic scene-text corpus with 10K indoor scenes and 1M descriptions at object, view, and room levels, which has the advantages of diverse scene data, rich textual descriptions, multi-grained 3D-text associations, and low collection cost. Utilizing the rich annotations in SynVL3D, we pre-train a simple and unified Transformer for aligning 3D and language with multi-grained pretraining tasks. Moreover, we propose a synthetic-to-real domain adaptation in downstream task fine-tuning process to address the domain shift. Through extensive experiments, we verify the effectiveness of our model design by achieving state-of-the-art performance on downstream tasks including visual grounding, dense captioning, and question answering.

Yinsong Xu, Aidong Men, Yang Liu et al.

In deep learning, initializing models with pre-trained weights has become the de facto practice for various downstream tasks. Many unsupervised domain adaptation (UDA) methods typically adopt a backbone pre-trained on ImageNet, and focus on reducing the source-target domain discrepancy. However, the impact of pre-training on adaptation received little attention. In this study, we delve into UDA from the novel perspective of pre-training. We first demonstrate the impact of pre-training by analyzing the dynamic distribution discrepancies between pre-training data domain and the source/ target domain during adaptation. Then, we reveal that the target error also stems from the pre-training in the following two factors: 1) empirically, target error arises from the gradually degenerative pre-trained knowledge during adaptation; 2) theoretically, the error bound depends on difference between the gradient of loss function, \ie, on the target domain and pre-training data domain. To address these two issues, we redefine UDA as a three-domain problem, \ie, source domain, target domain, and pre-training data domain; then we propose a novel framework, named TriDA. We maintain the pre-trained knowledge and improve the error bound by incorporating pre-training data into adaptation for both vanilla UDA and source-free UDA scenarios. For efficiency, we introduce a selection strategy for pre-training data, and offer a solution with synthesized images when pre-training data is unavailable during adaptation. Notably, TriDA is effective even with a small amount of pre-training or synthesized images, and seamlessly complements the two scenario UDA methods, demonstrating state-of-the-art performance across multiple benchmarks. We hope our work provides new insights for better understanding and application of domain adaptation.

Jinye Li, Aidong Men, Yang Liu et al.

Cardiovascular diseases (CVDs) remain a leading cause of death globally, necessitating continuous, accurate non-invasive cardiac monitoring. While non-contact radar-based approaches show great promise, they often employ a single "distortion-driven" or "perception-driven" paradigm, frequently facing a trade-off between "low distortion but weak semantic information" and "high perceptual fidelity but poor interpretability." To address this, we propose a Three-stage Distortion-Perception Pre-Training Model (TriDP-PTM), a radar-based multi-scale fusion dual-path framework that systematically compares the "direct radar-to-task" path against an "indirect radar-to-ECG-to-task" path. By integrating an ECG generator with a feature discriminator to form a composite loss function, our approach effectively incorporates medical priors - such as ECG morphology and rhythm - into downstream tasks. Through empirical analysis, we reveal that this trade-off manifests in three distinct phases (Positive-Sum, Coopetitive, and Negative-Sum), showing optimal downstream clinical accuracy typically emerges in the coopetitive stage. Extensive experiments on a dataset involving 30 subjects across 5 physiological states reveal that the indirect path consistently outperforms the direct path in diverse tasks, achieving 0.80 mean IoU in waveform segmentation, 98.3% average classification accuracy across four tasks, and a 56% MAE reduction in blood pressure regression compared to the strongest baselines. These findings validate our framework and indicate that, within the indirect radar-to-ECG pathway, appropriately weighting distortion and perception losses to operate in the coopetitive regime is critical for achieving both clinically interpretable ECG morphology and strong downstream accuracy in non-contact cardiac monitoring.

Jinye Li, Chenxi Fu, Minghang Zheng et al.

Cardiac function evaluation necessitates continuous, non-invasive monitoring, a capability limited in MRI. Millimeter-wave (mmWave) radar and its Synthetic Aperture Radar (SAR) mode offer a privacy-preserving and portable point-of-care clinical applications. However, reconstructing high-fidelity 3D cardiac geometry from SAR remains an open challenge. Traditional radar methods generate sparse point clouds that lack continuous surface topology. Meanwhile, direct application of optical reconstruction networks performs poorly due to the severe speckle noise and ambiguous boundaries inherent in SAR images. To bridge this gap, we propose SAR2Mesh, a novel framework that reformulates the task as a coarse-to-fine mesh deformation process. By initializing with a topological template, our approach explicitly preserves anatomical connectivity through progressive mesh deformation.We introduce a geometry-aware feature projection module to extract multi-view features via 3D-to-2D sampling, and a physics-informed radar loss to enforce consistency between the predicted geometry and raw radar echoes. Furthermore, we present Cardiac Mesh-SAR, the first large-scale paired SAR-mesh dataset. Extensive experiments demonstrate that SAR2Mesh significantly outperforms existing image-based baselines, achieving accurate and physically consistent cardiac reconstructions.

Jiaqi Tang, Weixuan Xu, Shu Zhang et al.

Vision Transformers (ViTs) have revolutionized medical image analysis, yet their data-hungry nature clashes with the scarcity and privacy constraints of clinical archives. Formula-Driven Supervised Learning (FDSL) has emerged as a promising solution to this bottleneck, synthesizing infinite annotated samples from mathematical formulas without utilizing real patient data. However, existing FDSL paradigms rely on simple geometric shapes with homogeneous intensities, creating a substantial gap by neglecting tissue textures and noise patterns inherent in modalities like CT and MRI. In this paper, we identify a critical optimization conflict termed boundary aliasing: when high-frequency synthetic textures are naively added, they corrupt the image gradient signals necessary for learning structural boundaries, causing the model to fail in delineating real anatomical margins. To bridge this gap, we propose a novel Physics-inspired Spatially-Decoupled Synthesis framework. Our approach orthogonalizes the synthesis process: it first constructs a gradient-shielded buffer zone based on boundary distance to ensure stable shape learning, and subsequently injects physics-driven spectral textures into the object core. This design effectively reconciles robust shape representation learning with invariance to acquisition noise. Extensive experiments on the BTCV and MSD datasets demonstrate that our method significantly outperforms previous FDSL, as well as SSL methods trained on real-world medical datasets, by 1.43% on BTCV and up to 1.51% on MSD task, offering a scalable, annotation-free foundation for medical ViTs. The code will be made publicly available upon acceptance.

Jiaqi Tang, Mengyan Zheng, Shu Zhang et al.

Vision Transformers (ViTs) excel in 3D medical segmentation but require massive annotated datasets. While Self-Supervised Learning (SSL) mitigates this using unlabeled data, it still faces strict privacy and logistical barriers. Formula-Driven Supervised Learning (FDSL) offers a privacy-preserving alternative by pre-training on synthetic mathematical primitives. However, a critical semantic gap limits its efficacy: generic shapes lack the morphological fidelity, fixed spatial layouts, and inter-organ relationships of real anatomy, preventing models from learning essential global structural priors. To bridge this gap, we propose an Anatomy-Informed Synthetic Supervised Pre-training framework unifying FDSL's infinite scalability with anatomical realism. We replace basic primitives with a lightweight shape bank with de-identified, label-only segmentation masks from 5 subjects. Furthermore, we introduce a structure-aware sequential placement strategy to govern the patch synthesis process. Instead of random placement, we enforce physiological plausibility using spatial anchors for correct localization and a topological graph to manage inter-organ interactions (e.g., preventing impossible overlaps). Extensive experiments on BTCV and MSD datasets demonstrate that our method significantly outperforms state-of-the-art FDSL baselines and SSL methods by 1.74\% and up to 1.66\%, while exhibiting a robust scaling effect where performance improves with increased synthetic data volume. This provides a data-efficient, privacy-compliant solution for medical segmentation. The code will be made publicly available upon acceptance.

Yuanye Liu, Zheyao Gao, Nannan Shi et al.

Accurate staging of liver fibrosis from magnetic resonance imaging (MRI) is crucial in clinical practice. While conventional methods often focus on a specific sub-region, multi-view learning captures more information by analyzing multiple patches simultaneously. However, previous multi-view approaches could not typically calculate uncertainty by nature, and they generally integrate features from different views in a black-box fashion, hence compromising reliability as well as interpretability of the resulting models. In this work, we propose a new multi-view method based on evidential learning, referred to as MERIT, which tackles the two challenges in a unified framework. MERIT enables uncertainty quantification of the predictions to enhance reliability, and employs a logic-based combination rule to improve interpretability. Specifically, MERIT models the prediction from each sub-view as an opinion with quantified uncertainty under the guidance of the subjective logic theory. Furthermore, a distribution-aware base rate is introduced to enhance performance, particularly in scenarios involving class distribution shifts. Finally, MERIT adopts a feature-specific combination rule to explicitly fuse multi-view predictions, thereby enhancing interpretability. Results have showcased the effectiveness of the proposed MERIT, highlighting the reliability and offering both ad-hoc and post-hoc interpretability. They also illustrate that MERIT can elucidate the significance of each view in the decision-making process for liver fibrosis staging. Our code has be released via https://github.com/HenryLau7/MERIT.

Yinsong Xu, Jiaqi Tang, Aidong Men et al.

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention and the domain gap between natural and medical images poses significant obstacles. This paper introduces a novel training-free evidential prompt generation method named EviPrompt to overcome these issues. The proposed method, built on the inherent similarities within medical images, requires only a single reference image-annotation pair, making it a training-free solution that significantly reduces the need for extensive labeling and computational resources. First, to automatically generate prompts for SAM in medical images, we introduce an evidential method based on uncertainty estimation without the interaction of clinical experts. Then, we incorporate the human prior into the prompts, which is vital for alleviating the domain gap between natural and medical images and enhancing the applicability and usefulness of SAM in medical scenarios. EviPrompt represents an efficient and robust approach to medical image segmentation, with evaluations across a broad range of tasks and modalities confirming its efficacy.

Rongxiao Guo, Qingchao Chen

Millimeter-wave (mmWave) radar has shown great potential for contactless, privacy-preserving, and robust human sensing, yet existing mmWave-based human mesh reconstruction (HMR) studies are still limited by the lack of benchmarks for generalization analysis under configuration shifts and fair comparison of different algorithms. To address the limitation, we present DGHMesh, a large-scale dual-radar mmWave dataset and generalization-focused benchmark for HMR. It contains data from 15 subjects performing 8 actions, with 360,000 synchronized frames collected from FMCW radar, SFCW radar, RGB images, and high-precision 3D HMR annotations. In addition, the dataset provides synchronized raw I/Q data from both radar modalities and accurately calibrated radar spatial positions. The benchmark is designed to evaluate HMR methods under diverse measurement configurations, including human position shifts, human orientation shifts, subarray size variations, and cross-subject settings. Based on DGHMesh, we also propose mmPTM, a query-based multi-radar fusion framework that jointly exploits point clouds and imaging tubes for HMR. Extensive experiments are conducted against representative baselines under different settings. The results demonstrate that mmPTM consistently achieves outstanding accuracy and competitive generalization capability across multiple sub-benchmarks, validating the effectiveness of multi-radar fusion and the practical value of the proposed dataset and benchmark for mmWave-based HMR research. DGHMesh and mmPTM are publicly available at https://github.com/SPIresearch/DGHMesh.(The complete benchmark and code will be released after paper publication)

Jiayi Gao, Changcheng Hua, Qingchao Chen et al.

Identity-preserving text-to-video (IPT2V) generation creates videos faithful to both a reference subject image and a text prompt. While fine-tuning large pretrained video diffusion models on ID-matched data achieves state-of-the-art results on IPT2V, data scarcity and high tuning costs hinder broader improvement. We thus introduce a Training-Free Prompt, Image, and Guidance Enhancement (TPIGE) framework that bridges the semantic gap between the video description and the reference image and design sampling guidance that enhances identity preservation and video quality, achieving performance gains at minimal cost.Specifically, we first propose Face Aware Prompt Enhancement, using GPT-4o to enhance the text prompt with facial details derived from the reference image. We then propose Prompt Aware Reference Image Enhancement, leveraging an identity-preserving image generator to refine the reference image, rectifying conflicts with the text prompt. The above mutual refinement significantly improves input quality before video generation. Finally, we propose ID-Aware Spatiotemporal Guidance Enhancement, utilizing unified gradients to optimize identity preservation and video quality jointly during generation.Our method outperforms prior work and is validated by automatic and human evaluations on a 1000 video test set, winning first place in the ACM Multimedia 2025 Identity-Preserving Video Generation Challenge, demonstrating state-of-the-art performance and strong generality. The code is available at https://github.com/Andyplus1/IPT2V.git.

Chuanchuan Sun, Zhen Yu, Qin Fan et al.

Background: Pregnancy-associated thrombotic microangiopathy (P-TMA) is rare but life-threatening. Early risk prediction before overt clinical presentation remains challenging, as the associated laboratory abnormalities are subtle, multidimensional, and frequently masked by common physiological changes such as gestational thrombocytopenia and pregnancy-related proteinuria, thus overlapping heavily with benign obstetric and renal conditions. This complexity is poorly captured by univariate or rule-based approaches; however, it is addressable by machine learning, which can extract latent, time-dependent risk signatures from longitudinal clinical tests. Methods: This retrospective study included 300 pregnancies comprising 142 P-TMA cases and 158 controls. After exclusion of identifiers and non-informative variables, 146 longitudinal laboratory predictors were retained. Participants were divided into a training cohort (80%) and a held-out test cohort (20%) using stratified sampling. Five algorithms were evaluated: logistic regression, support vector machine with radial basis function kernel, random forest, extra trees, and gradient boosting. The final model was selected by mean cross-validated AUROC, refitted on the full training cohort, and evaluated once in the held-out test cohort. Interpretability analyses examined global feature importance and distributional patterns of leading predictors. Results: Gradient boosting was prespecified by cross-validation in the training cohort. The model achieved an AUROC of 0.872 (95% CI: 0.769-0.952) and an AUPRC of 0.883 (95% CI: 0.780-0.959) in a held-out test cohort, with sensitivity of 0.750 and specificity of 0.812. Conclusions: Longitudinal clinical laboratory tests obtained during routine care contained informative and clinically plausible signals for P-TMA risk. Notably, cystatin C at week 6 showed promise as an early monitoring indicator.

Zhu Xu, Ting Lei, Zhimin Li et al.

Dynamic Scene Graph Generation (DSGG) aims to create a scene graph for each video frame by detecting objects and predicting their relationships. Weakly Supervised DSGG (WS-DSGG) reduces annotation workload by using an unlocalized scene graph from a single frame per video for training. Existing WS-DSGG methods depend on an off-the-shelf external object detector to generate pseudo labels for subsequent DSGG training. However, detectors trained on static, object-centric images struggle in dynamic, relation-aware scenarios required for DSGG, leading to inaccurate localization and low-confidence proposals. To address the challenges posed by external object detectors in WS-DSGG, we propose a Temporal-enhanced Relation-aware Knowledge Transferring (TRKT) method, which leverages knowledge to enhance detection in relation-aware dynamic scenarios. TRKT is built on two key components:(1)Relation-aware knowledge mining: we first employ object and relation class decoders that generate category-specific attention maps to highlight both object regions and interactive areas. Then we propose an Inter-frame Attention Augmentation strategy that exploits optical flow for neighboring frames to enhance the attention maps, making them motion-aware and robust to motion blur. This step yields relation- and motion-aware knowledge mining for WS-DSGG. (2) we introduce a Dual-stream Fusion Module that integrates category-specific attention maps into external detections to refine object localization and boost confidence scores for object proposals. Extensive experiments demonstrate that TRKT achieves state-of-the-art performance on Action Genome dataset. Our code is avaliable at https://github.com/XZPKU/TRKT.git.

Ting Lei, Shaofeng Yin, Qingchao Chen et al.

Open Vocabulary Human-Object Interaction (HOI) detection aims to detect interactions between humans and objects while generalizing to novel interaction classes beyond the training set. Current methods often rely on Vision and Language Models (VLMs) but face challenges due to suboptimal image encoders, as image-level pre-training does not align well with the fine-grained region-level interaction detection required for HOI. Additionally, effectively encoding textual descriptions of visual appearances remains difficult, limiting the model's ability to capture detailed HOI relationships. To address these issues, we propose INteraction-aware Prompting with Concept Calibration (INP-CC), an end-to-end open-vocabulary HOI detector that integrates interaction-aware prompts and concept calibration. Specifically, we propose an interaction-aware prompt generator that dynamically generates a compact set of prompts based on the input scene, enabling selective sharing among similar interactions. This approach directs the model's attention to key interaction patterns rather than generic image-level semantics, enhancing HOI detection. Furthermore, we refine HOI concept representations through language model-guided calibration, which helps distinguish diverse HOI concepts by investigating visual similarities across categories. A negative sampling strategy is also employed to improve inter-modal similarity modeling, enabling the model to better differentiate visually similar but semantically distinct actions. Extensive experimental results demonstrate that INP-CC significantly outperforms state-of-the-art models on the SWIG-HOI and HICO-DET datasets. Code is available at https://github.com/ltttpku/INP-CC.

Yu Wang, Qingchao Chen

Self-supervised pretraining has become the mainstream approach for learning MRI representations from unlabeled scans. However, most existing objectives still treat each scan primarily as static aggregations of slices, patches or volumes. We ask whether there exists an intrinsic form of self-supervision signal that is different from reconstructing the masked patches, through transforming the 3D volumes into controllable 2D rendered sequences: by rendering slices at continuous positions, orientations, and scales, a 3D volume can be converted into dense video-action sequences whose controls are the action trajectories. We study this formulation with an action-conditioned pretraining objective, where a tokenizer encodes slice observations and a latent dynamics model predicts the evolution of latent features. Across representative anatomical and spatial downstream tasks, the proposed pretraining is evaluated against standard static-volume baselines, tokenizer-only pretraining, and dynamics variants without aligned actions. These results suggest that controllable MRI slice navigation provides a useful complementary pretraining interface for learning anatomical and spatial representations from large unlabeled MRI collections.

Zhen Yu, Yang Liu, Qingchao Chen

It is essential but challenging to share medical image datasets due to privacy issues, which prohibit building foundation models and knowledge transfer. In this paper, we propose a novel dataset distillation method to condense the original medical image datasets into a synthetic one that preserves useful information for building an analysis model without accessing the original datasets. Existing methods tackle only natural images by randomly matching parts of the training trajectories of the model parameters trained by the whole real datasets. However, through extensive experiments on medical image datasets, the training process is extremely unstable and achieves inferior distillation results. To solve these barriers, we propose to design a novel progressive trajectory matching strategy to improve the training stability for medical image dataset distillation. Additionally, it is observed that improved stability prevents the synthetic dataset diversity and final performance improvements. Therefore, we propose a dynamic overlap mitigation module that improves the synthetic dataset diversity by dynamically eliminating the overlap across different images and retraining parts of the synthetic images for better convergence. Finally, we propose a new medical image dataset distillation benchmark of various modalities and configurations to promote fair evaluations. It is validated that our proposed method achieves 8.33% improvement over previous state-of-the-art methods on average, and 11.7% improvement when ipc=2 (i.e., image per class is 2). Codes and benchmarks will be released.

Wentao Mo, Qingchao Chen, Yuxin Peng et al.

The advancement of 3D vision-language (3D VL) learning is hindered by several limitations in existing 3D VL datasets: they rarely necessitate reasoning beyond a close range of objects in single viewpoint, and annotations often link instructions to single objects, missing richer contextual alignments between multiple objects. This significantly curtails the development of models capable of deep, multi-view 3D scene understanding over distant objects. To address these challenges, we introduce MV-ScanQA, a novel 3D question answering dataset where 68% of questions explicitly require integrating information from multiple views (compared to less than 7% in existing datasets), thereby rigorously testing multi-view compositional reasoning. To facilitate the training of models for such demanding scenarios, we present TripAlign dataset, a large-scale and low-cost 2D-3D-language pre-training corpus containing 1M <2D view, set of 3D objects, text> triplets that explicitly aligns groups of contextually related objects with text, providing richer, view-grounded multi-object multimodal alignment signals than previous single-object annotations. We further develop LEGO, a baseline method for the multi-view reasoning challenge in MV-ScanQA, transferring knowledge from pre-trained 2D LVLMs to 3D domain with TripAlign. Empirically, LEGO pre-trained on TripAlign achieves state-of-the-art performance not only on the proposed MV-ScanQA, but also on existing benchmarks for 3D dense captioning and question answering. Datasets and code are available at https://matthewdm0816.github.io/tripalign-mvscanqa.

Jiangbo Pei, Ruizhe Li, Aidong Men et al.

Conventional Multi-Source Free Domain Adaptation (MSFDA) assumes that each source domain provides a single source model, and all source models adopt a uniform architecture. This paper introduces Zoo-MSFDA, a more general setting that allows each source domain to offer a zoo of multiple source models with different architectures. While it enriches the source knowledge, Zoo-MSFDA risks being dominated by suboptimal/harmful models. To address this issue, we theoretically analyze the model selection problem in Zoo-MSFDA, and introduce two principles: transferability principle and diversity principle. Recognizing the challenge of measuring transferability, we subsequently propose a novel Source-Free Unsupervised Transferability Estimation (SUTE). It enables assessing and comparing transferability across multiple source models with different architectures under domain shift, without requiring target labels and source data. Based on above, we introduce a Selection, Ensemble, and Adaptation (SEA) framework to address Zoo-MSFDA, which consists of: 1) source models selection based on the proposed principles and SUTE; 2) ensemble construction based on SUTE-estimated transferability; 3) target-domain adaptation of the ensemble model. Evaluations demonstrate that our SEA framework, with the introduced Zoo-MSFDA setting, significantly improves adaptation performance (e.g., 13.5% on DomainNet). Additionally, our SUTE achieves state-of-the-art performance in transferability estimation.

Jiaying Zhou, Qingchao Chen

Open-Vocabulary Object Detection (OVOD) aims to generalize object recognition to novel categories, while Weakly Supervised OVOD (WS-OVOD) extends this by combining box-level annotations with image-level labels. Despite recent progress, two critical challenges persist in this setting. First, existing semantic prototypes, even when enriched by LLMs, are static and limited, failing to capture the rich intra-class visual variations induced by different object states (e.g., a cat's pose). Second, the standard pseudo-box generation introduces a semantic mismatch between visual region proposals (which contain context) and object-centric text embeddings. To tackle these issues, we introduce two complementary prototype enhancement strategies. To capture intra-class variations in appearance and state, we propose the State-Enhanced Semantic Prototypes (SESP), which generates state-aware textual descriptions (e.g., "a sleeping cat") to capture diverse object appearances, yielding more discriminative prototypes. Building on this, we further introduce Scene-Augmented Pseudo Prototypes (SAPP) to address the semantic mismatch. SAPP incorporates contextual semantics (e.g., "cat lying on sofa") and utilizes a soft alignment mechanism to promote contextually consistent visual-textual representations. By integrating SESP and SAPP, our method effectively enhances both the richness of semantic prototypes and the visual-textual alignment, achieving notable improvements.

Jiaqi Tang, Yinsong Xu, Yang Liu et al.

Multi-modal fusion often suffers from modality competition during joint training, where one modality dominates the learning process, leaving others under-optimized. Overlooking the critical impact of the model's initial state, most existing methods address this issue during the joint learning stage. In this study, we introduce a two-stage training framework to shape the initial states through unimodal training before the joint training. First, we propose the concept of Effective Competitive Strength (ECS) to quantify a modality's competitive strength. Our theoretical analysis further reveals that properly shaping the initial ECS by unimodal training achieves a provably tighter error bound. However, ECS is computationally intractable in deep neural networks. To bridge this gap, we develop a framework comprising two core components: a fine-grained computable diagnostic metric and an asynchronous training controller. For the metric, we first prove that mutual information(MI) is a principled proxy for ECS. Considering MI is induced by per-modality marginals and thus treats each modality in isolation, we further propose FastPID, a computationally efficient and differentiable solver for partial information decomposition, which decomposes the joint distribution's information into fine-grained measurements: modality-specific uniqueness, redundancy, and synergy. Guided by these measurements, our asynchronous controller dynamically balances modalities by monitoring uniqueness and locates the ideal initial state to start joint training by tracking peak synergy. Experiments on diverse benchmarks demonstrate that our method achieves state-of-the-art performance. Our work establishes that shaping the pre-fusion models' initial state is a powerful strategy that eases competition before it starts, reliably unlocking synergistic multi-modal fusion.

Zijing Zhao, Zhu Xu, Qingchao Chen et al.

As a fundamental task for indoor scene understanding, 3D object detection has been extensively studied, and the accuracy on indoor point cloud data has been substantially improved. However, existing researches have been conducted on limited datasets, where the training and testing sets share the same distribution. In this paper, we consider the task of adapting indoor 3D object detectors from one dataset to another, presenting a comprehensive benchmark with ScanNet, SUN RGB-D and 3D Front datasets, as well as our newly proposed large-scale datasets ProcTHOR-OD and ProcFront generated by a 3D simulator. Since indoor point cloud datasets are collected and constructed in different ways, the object detectors are likely to overfit to specific factors within each dataset, such as point cloud quality, bounding box layout and instance features. We conduct experiments across datasets on different adaptation scenarios including synthetic-to-real adaptation, point cloud quality adaptation, layout adaptation and instance feature adaptation, analyzing the impact of different domain gaps on 3D object detectors. We also introduce several approaches to improve adaptation performances, providing baselines for domain adaptive indoor 3D object detection, hoping that future works may propose detectors with stronger generalization ability across domains. Our project homepage can be found in https://jeremyzhao1998.github.io/DAVoteNet-release/.

Jiaqi Tang, Yinsong Xu, Qingchao Chen

Object classification models utilizing point cloud data are fundamental for 3D media understanding, yet they often struggle with unseen or out-of-distribution (OOD) scenarios. Existing point cloud unsupervised domain adaptation (UDA) methods typically employ a multi-task learning (MTL) framework that combines primary classification tasks with auxiliary self-supervision tasks to bridge the gap between cross-domain feature distributions. However, our further experiments demonstrate that not all gradients from self-supervision tasks are beneficial and some may negatively impact the classification performance. In this paper, we propose a novel solution, termed Saliency Map-based Data Sampling Block (SM-DSB), to mitigate these gradient conflicts. Specifically, our method designs a new scoring mechanism based on the skewness of 3D saliency maps to estimate gradient conflicts without requiring target labels. Leveraging this, we develop a sample selection strategy that dynamically filters out samples whose self-supervision gradients are not beneficial for the classification. Our approach is scalable, introducing modest computational overhead, and can be integrated into all the point cloud UDA MTL frameworks. Extensive evaluations demonstrate that our method outperforms state-of-the-art approaches. In addition, we provide a new perspective on understanding the UDA problem through back-propagation analysis.

Tianqi Tu, Hui Wang, Jiangbo Pei et al.

Background: Renal chronicity indices (CI) have been identified as strong predictors of long-term outcomes in lupus nephritis (LN) patients. However, assessment by pathologists is hindered by challenges such as substantial time requirements, high interobserver variation, and susceptibility to fatigue. This study aims to develop an effective deep learning (DL) pipeline that automates the assessment of CI and provides valuable prognostic insights from a disease-specific perspective. Methods: We curated a dataset comprising 282 slides obtained from 141 patients across two independent cohorts with a complete 10-years follow-up. Our DL pipeline was developed on 60 slides (22,410 patch images) from 30 patients in the training cohort and evaluated on both an internal testing set (148 slides, 77,605 patch images) and an external testing set (74 slides, 27,522 patch images). Results: The study included two cohorts with slight demographic differences, particularly in age and hemoglobin levels. The DL pipeline showed high segmentation performance across tissue compartments and histopathologic lesions, outperforming state-of-the-art methods. The DL pipeline also demonstrated a strong correlation with pathologists in assessing CI, significantly improving interobserver agreement. Additionally, the DL pipeline enhanced prognostic accuracy, particularly in outcome prediction, when combined with clinical parameters and pathologist-assessed CIs Conclusions: The DL pipeline demonstrated accuracy and efficiency in assessing CI in LN, showing promise in improving interobserver agreement among pathologists. It also exhibited significant value in prognostic analysis and enhancing outcome prediction in LN patients, offering a valuable tool for clinical decision-making.

Zhen Yu, Jianan Han, Yang Liu et al.

Single-cell RNA sequencing (scRNA-seq) technology has profiled hundreds of millions of human cells across organs, diseases, development and perturbations to date. However, the high-dimensional sparsity, batch effect noise, category imbalance, and ever-increasing data scale of the original sequencing data pose significant challenges for multi-center knowledge transfer, data fusion, and cross-validation between scRNA-seq datasets. To address these barriers, (1) we first propose a latent codes-based scRNA-seq dataset distillation framework named scDD, which transfers and distills foundation model knowledge and original dataset information into a compact latent space and generates synthetic scRNA-seq dataset by a generator to replace the original dataset. Then, (2) we propose a single-step conditional diffusion generator named SCDG, which perform single-step gradient back-propagation to help scDD optimize distillation quality and avoid gradient decay caused by multi-step back-propagation. Meanwhile, SCDG ensures the scRNA-seq data characteristics and inter-class discriminability of the synthetic dataset through flexible conditional control and generation quality assurance. Finally, we propose a comprehensive benchmark to evaluate the performance of scRNA-seq dataset distillation in different data analysis tasks. It is validated that our proposed method can achieve 7.61% absolute and 15.70% relative improvement over previous state-of-the-art methods on average task.

Qianye Yang, Yunguan Fu, Francesco Giganti et al.

Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program. In this paper, we describe a learning-based image registration algorithm to quantify changes on regions of interest between a pair of images from the same patient, acquired at two different time points. Combining intensity-based similarity and gland segmentation as weak supervision, the population-data-trained registration networks significantly lowered the target registration errors (TREs) on holdout patient data, compared with those before registration and those from an iterative registration algorithm. Furthermore, this work provides a quantitative analysis on several longitudinal-data-sampling strategies and, in turn, we propose a novel regularisation method based on maximum mean discrepancy, between differently-sampled training image pairs. Based on 216 3D MR images from 86 patients, we report a mean TRE of 5.6 mm and show statistically significant differences between the different training data sampling strategies.