Rainer A. Leitgeb

Thomas Schlegl, Heiko Stino, Michael Niederleithner et al.

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and localization in optical coherence tomography en face images of the retina. We examine the effect of domain knowledge driven spatial complexity reduction on the resulting optic nerve head segmentation and localization performance. We present a machine learning approach for segmenting optic nerve head in 2D en face projections of 3D widefield swept source optical coherence tomography scans that enables the automated assessment of large amounts of data. Evaluation on manually annotated 2D en face images of the retina demonstrates that training of a standard U-Net can yield improved optic nerve head segmentation and localization performance when the underlying pixel-level binary classification task is spatially relaxed through domain knowledge.

Ali Yavari, Alireza Mohamadi, Elham Beydaghi et al.

Ensuring the reliability of deep neural networks (DNNs) in the presence of real world noise and intentional perturbations remains a significant challenge. To address this, attribution methods have been proposed, though their efficacy remains suboptimal and necessitates further refinement. In this paper, we propose a novel category of transferable adversarial attacks, called transferable frequency-aware attacks, enabling frequency-aware exploration via both high-and low-frequency components. Based on this type of attacks, we also propose a novel attribution method, named Frequency-Aware Model Parameter Explorer (FAMPE), which improves the explainability for DNNs. Relative to the current state-of-the-art method AttEXplore, our FAMPE attains an average gain of 13.02% in Insertion Score, thereby outperforming existing approaches. Through detailed ablation studies, we also investigate the role of both high- and low-frequency components in explainability.