Javed Mostafa

Mohammad Golam Kibria, Lauren Kucirka, Alison Stuebe et al.

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in decision-making. However, the clinical adoption of such models is scarce due to multifaceted implementation issues, with the explainability of AI models being among them. One of the substantially documented areas of concern is the unclear AI explainability that negatively influences clinicians` considerations for accepting the complex model. With a usability study engaging 20 U.S.-based clinicians and following the qualitative reflexive thematic analysis, this study develops and presents a concrete framework and an operational definition of explainability. The framework can inform the required customizations and feature developments in AI tools to support clinicians` preferences and enhance their acceptance.

Michael Segundo Ortiz, Kazuhiro Seki, Javed Mostafa

The current mode of biomedical literature search is severely limited in effectively finding information relevant to specialists. A potential approach to solving this problem is exploratory search, which allows users to interactively navigate through a vast document collection. As the first step toward exploratory search for specialists in biomedicine, this paper develops a methodology to evaluate quality of document clusters. For this purpose, we incorporate human expertise into data set creation and evaluation framework by leveraging MeSH terms as semantic anchors. In addition, we investigate the benefit of full-text data for improving cluster quality.

Michael Segundo Ortiz, Sam Bubnovich, Mengqian Wang et al.

The largest collection of medical evidence in the world is PubMed. However, the significant barrier in accessing and extracting information is information organization. A factor that contributes towards this barrier is managing medical controlled vocabularies that allow us to systematically and consistently organize, index, and search biomedical literature. Additionally, from users' perspective, to ultimately improve access, visualization is likely to play a powerful role. There is a strong link between information organization and information visualization, as many powerful visualizations depend on clustering methods. To improve visualization, therefore, one has to develop concrete and scalable measures for vocabularies used in indexing and their impact on document clustering. The focus of this study is on the development and evaluation of clustering methods. The paper concludes with demonstration of downstream network visualizations and their impact on discovering potentially valuable and latent genetic and molecular associations.