Wenqian Cui

Jinhu Qi, Muzhi Li, Jiahong Liu et al.

Agentic AI systems -- Large Language Models (LLMs) augmented with planning, tool use, memory, and long-horizon interactions -- can execute complex tasks autonomously, but their multi-step trajectories introduce new failure modes that challenge trustworthiness. This survey provides a focused examination of trustworthy agentic AI through two core dimensions that are critical for high-risk deployments: Safety and Robustness, and Privacy and System Security. For each dimension, we clarify key concepts, identify where risks emerge along the agent workflow, and summarize stage-targeted mitigation strategies. Other trustworthiness aspects (value alignment, transparency, fairness, and accountability) are discussed as relevant context rather than parallel chapters. To support consistent comparison and deployment decisions, we consolidate evaluation into a unified metrics-and-benchmarks hub, emphasizing both outcome and process signals (e.g., constraint violations, trace completeness, and adversarial success rates) and offering scenario-to-metric guidance for release gating. We conclude by outlining open challenges such as self-evolving agents, runtime monitoring and verification, privacy-preserving personalization, and the trust-utility trade-off, and present a case study of real-world security failures in open-source agentic systems. Our goal is to serve as a practical reference for researchers and practitioners building trustworthy agentic systems in high-stakes environments.

Wenqian Cui, Xiaoqi Jiao, Ziqiao Meng et al.

With the rising need for speech-based interaction models, end-to-end Spoken Language Models (SLMs) have emerged as a promising solution. While these models require comprehensive world knowledge for meaningful and reliable human interactions, existing question-answering (QA) benchmarks fall short in evaluating SLMs' knowledge understanding due to their inability to support end-to-end speech evaluation and account for varied input audio conditions. To address these limitations, we present VoxEval, a novel SpeechQA benchmark that assesses SLMs' knowledge understanding through pure speech interactions. Our benchmark 1) uniquely maintains speech format for both inputs and outputs, 2) evaluates model robustness across diverse input audio conditions, and 3) pioneers the assessment of complex tasks like mathematical reasoning in spoken format. Systematic evaluation demonstrates that VoxEval presents significant challenges to current SLMs, revealing their sensitivity to varying audio conditions and highlighting the need to enhance reasoning capabilities in future development. We hope this benchmark could guide the advancement of more sophisticated and reliable SLMs. VoxEval dataset is available at: https://github.com/dreamtheater123/VoxEval

Dianzhi Yu, Conghao Xiong, Yankai Chen et al.

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical environment and continuous data streams, limiting its practical utility. While continual learning (CL) offers a solution to learn dynamically from new datasets, existing CL methods primarily focus on unimodal inputs and suffer from severe catastrophic forgetting in survival prediction. In real-world scenarios, multimodal inputs often provide comprehensive and complementary information, such as whole slide images and genomics; and neglecting inter-modal correlations negatively impacts the performance. To address the two challenges of catastrophic forgetting and complex inter-modal interactions between gigapixel whole slide images and genomics, we propose ConSurv, the first multimodal continual learning (MMCL) method for survival analysis. ConSurv incorporates two key components: Multi-staged Mixture of Experts (MS-MoE) and Feature Constrained Replay (FCR). MS-MoE captures both task-shared and task-specific knowledge at different learning stages of the network, including two modality encoders and the modality fusion component, learning inter-modal relationships. FCR further enhances learned knowledge and mitigates forgetting by restricting feature deviation of previous data at different levels, including encoder-level features of two modalities and the fusion-level representations. Additionally, we introduce a new benchmark integrating four datasets, Multimodal Survival Analysis Incremental Learning (MSAIL), for comprehensive evaluation in the CL setting. Extensive experiments demonstrate that ConSurv outperforms competing methods across multiple metrics.

Wenqian Cui, Xiangling Fu, Shaohui Liu et al.

Disease name normalization is an important task in the medical domain. It classifies disease names written in various formats into standardized names, serving as a fundamental component in smart healthcare systems for various disease-related functions. Nevertheless, the most significant obstacle to existing disease name normalization systems is the severe shortage of training data. Consequently, we present a novel data augmentation approach that includes a series of data augmentation techniques and some supporting modules to help mitigate the problem. Our proposed methods rely on the Structural Invariance property of disease names and the Hierarchy property of the disease classification system. The goal is to equip the models with extensive understanding of the disease names and the hierarchical structure of the disease name classification system. Through extensive experimentation, we illustrate that our proposed approach exhibits significant performance improvements across various baseline models and training objectives, particularly in scenarios with limited training data.

Wenqian Cui, Lei Zhu, Xiaohui Li et al.

Full-Duplex Speech Language Models (FD-SLMs) are specialized foundation models designed to enable natural, real-time spoken interactions by modeling complex conversational dynamics such as interruptions, backchannels, and overlapping speech, and End-to-end (e2e) FD-SLMs leverage real-world double-channel conversational data to capture nuanced two-speaker dialogue patterns for human-like interactions. However, they face a critical challenge -- their conversational abilities often degrade compared to pure-text conversation due to prolonged speech sequences and limited high-quality spoken dialogue data. While text-guided speech generation could mitigate these issues, it suffers from timing and length issues when integrating textual guidance into double-channel audio streams, disrupting the precise time alignment essential for natural interactions. To address these challenges, we propose TurnGuide, a novel planning-inspired approach that mimics human conversational planning by dynamically segmenting assistant speech into dialogue turns and generating turn-level text guidance before speech output, which effectively resolves both insertion timing and length challenges. Extensive experiments demonstrate our approach significantly improves e2e FD-SLMs' conversational abilities, enabling them to generate semantically meaningful and coherent speech while maintaining natural conversational flow. Demos are available at https://dreamtheater123.github.io/TurnGuide-Demo/. Code will be available at https://github.com/dreamtheater123/TurnGuide.

Wenqian Cui, Xiangling Fu, Shaohui Liu et al.

Disease name normalization is an important task in the medical domain. It classifies disease names written in various formats into standardized names, serving as a fundamental component in smart healthcare systems for various disease-related functions. Nevertheless, the most significant obstacle to existing disease name normalization systems is the severe shortage of training data. Consequently, we present a novel data augmentation approach that includes a series of data augmentation techniques and some supporting modules to help mitigate the problem. Through extensive experimentation, we illustrate that our proposed approach exhibits significant performance improvements across various baseline models and training objectives, particularly in scenarios with limited training data