Lei Wang

Biwen Lei, Yang Li, Xinhai Liu et al.

The creation of high-quality 3D assets, a cornerstone of modern game development, has long been characterized by labor-intensive and specialized workflows. This paper presents Hunyuan3D Studio, an end-to-end AI-powered content creation platform designed to revolutionize the game production pipeline by automating and streamlining the generation of game-ready 3D assets. At its core, Hunyuan3D Studio integrates a suite of advanced neural modules (such as Part-level 3D Generation, Polygon Generation, Semantic UV, etc.) into a cohesive and user-friendly system. This unified framework allows for the rapid transformation of a single concept image or textual description into a fully-realized, production-quality 3D model complete with optimized geometry and high-fidelity PBR textures. We demonstrate that assets generated by Hunyuan3D Studio are not only visually compelling but also adhere to the stringent technical requirements of contemporary game engines, significantly reducing iteration time and lowering the barrier to entry for 3D content creation. By providing a seamless bridge from creative intent to technical asset, Hunyuan3D Studio represents a significant leap forward for AI-assisted workflows in game development and interactive media.

Han Zhang, Fengji Ma, Jiamin Su et al.

Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on single-task learning (STL), which often fails to fully exploit the complementarities between tasks. Besides, it requires more computational resources while training and inference of each task independently. To address these issues, we propose a new unified Quantum-enhanced and task-Weighted Multi-Task Learning (QW-MTL) framework, specifically designed for ADMET classification tasks. Built upon the Chemprop-RDKit backbone, QW-MTL adopts quantum chemical descriptors to enrich molecular representations with additional information about the electronic structure and interactions. Meanwhile, it introduces a novel exponential task weighting scheme that combines dataset-scale priors with learnable parameters to achieve dynamic loss balancing across tasks. To the best of our knowledge, this is the first work to systematically conduct joint multi-task training across all 13 Therapeutics Data Commons (TDC) classification benchmarks, using leaderboard-style data splits to ensure a standardized and realistic evaluation setting. Extensive experimental results show that QW-MTL significantly outperforms single-task baselines on 12 out of 13 tasks, achieving high predictive performance with minimal model complexity and fast inference, demonstrating the effectiveness and efficiency of multi-task molecular learning enhanced by quantum-informed features and adaptive task weighting.