Nancy E. Thomas

Yi Cui, Yao Li, Jayson R. Miedema et al.

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology help us to reduce costs and increase the speed and accuracy of regions of interest detection and cancer diagnosis. In this work, we propose a patch-based region of interest detection method for melanocytic skin tumor whole-slide images. We work with a dataset that contains 165 primary melanomas and nevi Hematoxylin and Eosin whole-slide images and build a deep-learning method. The proposed method performs well on a hold-out test data set including five TCGA-SKCM slides (accuracy of 93.94\% in slide classification task and intersection over union rate of 41.27\% in the region of interest detection task), showing the outstanding performance of our model on melanocytic skin tumor. Even though we test the experiments on the skin tumor dataset, our work could also be extended to other medical image detection problems, such as various tumors' classification and prediction, to help and benefit the clinical evaluation and diagnosis of different tumors.

Yi Cui, Yao Li, Jayson R. Miedema et al.

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to reduce costs and increase the speed and accuracy of cancer diagnosis. We started with the UNC Melanocytic Tumor Dataset cohort that contains 160 hematoxylin and eosin whole-slide images of primary melanomas (86) and nevi (74). We randomly assigned 80% (134) as a training set and built an in-house deep-learning method to allow for classification, at the slide level, of nevi and melanomas. The proposed method performed well on the other 20% (26) test dataset; the accuracy of the slide classification task was 92.3% and our model also performed well in terms of predicting the region of interest annotated by the pathologists, showing excellent performance of our model on melanocytic skin tumors. Even though we tested the experiments on the skin tumor dataset, our work could also be extended to other medical image detection problems to benefit the clinical evaluation and diagnosis of different tumors.

Nancy Thomas, Saba Rahimi, Annita Vapsi et al.

Amidst escalating climate change, hurricanes are inflicting severe socioeconomic impacts, marked by heightened economic losses and increased displacement. Previous research utilized nighttime light data to predict the impact of hurricanes on economic losses. However, prior work did not provide a thorough analysis of the impact of combining different techniques for pre-processing nighttime light (NTL) data. Addressing this gap, our research explores a variety of NTL pre-processing techniques, including value thresholding, built masking, and quality filtering and imputation, applied to two distinct datasets, VSC-NTL and VNP46A2, at the zip code level. Experiments evaluate the correlation of the denoised NTL data with economic damages of Category 4-5 hurricanes in Florida. They reveal that the quality masking and imputation technique applied to VNP46A2 show a substantial correlation with economic damage data.

Victor Radermecker, Andrea Zanon, Nancy Thomas et al.

Understanding land cover holds considerable potential for a myriad of practical applications, particularly as data accessibility transitions from being exclusive to governmental and commercial entities to now including the broader research community. Nevertheless, although the data is accessible to any community member interested in exploration, there exists a formidable learning curve and no standardized process for accessing, pre-processing, and leveraging the data for subsequent tasks. In this study, we democratize this data by presenting a flexible and efficient end to end pipeline for working with the Dynamic World dataset, a cutting-edge near-real-time land use/land cover (LULC) dataset. This includes a pre-processing and representation framework which tackles noise removal, efficient extraction of large amounts of data, and re-representation of LULC data in a format well suited for several downstream tasks. To demonstrate the power of our pipeline, we use it to extract data for an urbanization prediction problem and build a suite of machine learning models with excellent performance. This task is easily generalizable to the prediction of any type of land cover and our pipeline is also compatible with a series of other downstream tasks.