Guanzhong Chen

Yukun Zhang, Guanzhong Chen, Zenglin Xu et al.

Cardiovascular diseases (CVDs) are currently the leading cause of death worldwide, highlighting the critical need for early diagnosis and treatment. Machine learning (ML) methods can help diagnose CVDs early, but their performance relies on access to substantial data with high quality. However, the sensitive nature of healthcare data often restricts individual clinical institutions from sharing data to train sufficiently generalized and unbiased ML models. Federated Learning (FL) is an emerging approach, which offers a promising solution by enabling collaborative model training across multiple participants without compromising the privacy of the individual data owners. However, to the best of our knowledge, there has been limited prior research applying FL to the cardiovascular disease domain. Moreover, existing FL benchmarks and datasets are typically simulated and may fall short of replicating the complexity of natural heterogeneity found in realistic datasets that challenges current FL algorithms. To address these gaps, this paper presents the first real-world FL benchmark for cardiovascular disease detection, named FedCVD. This benchmark comprises two major tasks: electrocardiogram (ECG) classification and echocardiogram (ECHO) segmentation, based on naturally scattered datasets constructed from the CVD data of seven institutions. Our extensive experiments on these datasets reveal that FL faces new challenges with real-world non-IID and long-tail data. The code and datasets of FedCVD are available https://github.com/SMILELab-FL/FedCVD.

Jinglong Luo, Guanzhong Chen, Yehong Zhang et al.

With the growing deployment of pre-trained models like Transformers on cloud platforms, privacy concerns about model parameters and inference data are intensifying. Existing Privacy-Preserving Transformer Inference (PPTI) frameworks face the "impossible trinity" of balancing privacy, efficiency, and performance: Secure Multi-Party Computation (SMPC)-based approaches ensure strong privacy but suffer from high computational overhead and performance losses; Conversely, permutation-based methods achieve near-plaintext efficiency and accuracy but compromise privacy by exposing sensitive model parameters and intermediate results. Bridging this gap with a single approach presents substantial challenges, motivating the introduction of CENTAUR, a groundbreaking PPTI framework that seamlessly integrates random permutations and SMPC to address the "impossible trinity". By designing efficient PPTI algorithms tailored to the structural properties of Transformer models, CENTAUR achieves an unprecedented balance among privacy, efficiency, and performance. Our experiments demonstrate CENTAUR's ability to resist diverse data reconstruction attacks, achieve plaintext-level inference accuracy, and boost inference speed by 5.0-30.4 times, unlocking new possibilities for secure and efficient AI deployment.