Yun Gu

Yulei Qin, Xingyu Chen, Chao Chen et al.

Recently, webly supervised learning (WSL) has been studied to leverage numerous and accessible data from the Internet. Most existing methods focus on learning noise-robust models from web images while neglecting the performance drop caused by the differences between web domain and real-world domain. However, only by tackling the performance gap above can we fully exploit the practical value of web datasets. To this end, we propose a Few-shot guided Prototypical (FoPro) representation learning method, which only needs a few labeled examples from reality and can significantly improve the performance in the real-world domain. Specifically, we initialize each class center with few-shot real-world data as the ``realistic" prototype. Then, the intra-class distance between web instances and ``realistic" prototypes is narrowed by contrastive learning. Finally, we measure image-prototype distance with a learnable metric. Prototypes are polished by adjacent high-quality web images and involved in removing distant out-of-distribution samples. In experiments, FoPro is trained on web datasets with a few real-world examples guided and evaluated on real-world datasets. Our method achieves the state-of-the-art performance on three fine-grained datasets and two large-scale datasets. Compared with existing WSL methods under the same few-shot settings, FoPro still excels in real-world generalization. Code is available at https://github.com/yuleiqin/fopro.

Yuncheng Yang, Meng Wei, Junjun He et al.

Transfer learning is a critical technique in training deep neural networks for the challenging medical image segmentation task that requires enormous resources. With the abundance of medical image data, many research institutions release models trained on various datasets that can form a huge pool of candidate source models to choose from. Hence, it's vital to estimate the source models' transferability (i.e., the ability to generalize across different downstream tasks) for proper and efficient model reuse. To make up for its deficiency when applying transfer learning to medical image segmentation, in this paper, we therefore propose a new Transferability Estimation (TE) method. We first analyze the drawbacks of using the existing TE algorithms for medical image segmentation and then design a source-free TE framework that considers both class consistency and feature variety for better estimation. Extensive experiments show that our method surpasses all current algorithms for transferability estimation in medical image segmentation. Code is available at https://github.com/EndoluminalSurgicalVision-IMR/CCFV

Chuyan Zhang, Yuncheng Yang, Hao Zheng et al.

Driven by the latest trend towards self-supervised learning (SSL), the paradigm of "pretraining-then-finetuning" has been extensively explored to enhance the performance of clinical applications with limited annotations. Previous literature on model finetuning has mainly focused on regularization terms and specific policy models, while the misalignment of channels between source and target models has not received sufficient attention. In this work, we revisited the dynamics of batch normalization (BN) layers and observed that the trainable affine parameters of BN serve as sensitive indicators of domain information. Therefore, Affine Collaborative Normalization (AC-Norm) is proposed for finetuning, which dynamically recalibrates the channels in the target model according to the cross-domain channel-wise correlations without adding extra parameters. Based on a single-step backpropagation, AC-Norm can also be utilized to measure the transferability of pretrained models. We evaluated AC-Norm against the vanilla finetuning and state-of-the-art fine-tuning methods on transferring diverse pretrained models to the diabetic retinopathy grade classification, retinal vessel segmentation, CT lung nodule segmentation/classification, CT liver-tumor segmentation and MRI cardiac segmentation tasks. Extensive experiments demonstrate that AC-Norm unanimously outperforms the vanilla finetuning by up to 4% improvement, even under significant domain shifts where the state-of-the-art methods bring no gains. We also prove the capability of AC-Norm in fast transferability estimation. Our code is available at https://github.com/EndoluminalSurgicalVision-IMR/ACNorm.

Yulei Qin, Xingyu Chen, Yunhang Shen et al.

Webly supervised learning has attracted increasing attention for its effectiveness in exploring publicly accessible data at scale without manual annotation. However, most existing methods of learning with web datasets are faced with challenges from label noise, and they have limited assumptions on clean samples under various noise. For instance, web images retrieved with queries of tiger cat (a cat species) and drumstick (a musical instrument) are almost dominated by images of tigers and chickens, which exacerbates the challenge of fine-grained visual concept learning. In this case, exploiting both web images and their associated texts is a requisite solution to combat real-world noise. In this paper, we propose Cross-modality Aligned Prototypes (CAPro), a unified prototypical contrastive learning framework to learn visual representations with correct semantics. For one thing, we leverage textual prototypes, which stem from the distinct concept definition of classes, to select clean images by text matching and thus disambiguate the formation of visual prototypes. For another, to handle missing and mismatched noisy texts, we resort to the visual feature space to complete and enhance individual texts and thereafter improve text matching. Such semantically aligned visual prototypes are further polished up with high-quality samples, and engaged in both cluster regularization and noise removal. Besides, we propose collective bootstrapping to encourage smoother and wiser label reference from appearance-similar instances in a manner of dictionary look-up. Extensive experiments on WebVision1k and NUS-WIDE (Web) demonstrate that CAPro well handles realistic noise under both single-label and multi-label scenarios. CAPro achieves new state-of-the-art performance and exhibits robustness to open-set recognition. Codes are available at https://github.com/yuleiqin/capro.

Yulei Qin, Yuncheng Yang, Pengcheng Guo et al.

Instruction tuning plays a critical role in aligning large language models (LLMs) with human preference. Despite the vast amount of open instruction datasets, naively training a LLM on all existing instructions may not be optimal and practical. To pinpoint the most beneficial datapoints, data assessment and selection methods have been proposed in the fields of natural language processing (NLP) and deep learning. However, under the context of instruction tuning, there still exists a gap in knowledge on what kind of data evaluation metrics can be employed and how they can be integrated into the selection mechanism. To bridge this gap, we present a comprehensive review on existing literature of data assessment and selection especially for instruction tuning of LLMs. We systematically categorize all applicable methods into quality-based, diversity-based, and importance-based ones where a unified, fine-grained taxonomy is structured. For each category, representative methods are elaborated to describe the landscape of relevant research. In addition, comparison between the latest methods is conducted on their officially reported results to provide in-depth discussions on their limitations. Finally, we summarize the open challenges and propose the promosing avenues for future studies. All related contents are available at https://github.com/yuleiqin/fantastic-data-engineering.

Jiasheng Xu, Tianyi Zhang, Yangqian Wu et al.

Endobronchial intervention is increasingly used as a minimally invasive means for the treatment of pulmonary diseases. In order to reduce the difficulty of manipulation in complex airway networks, robust lumen detection is essential for intraoperative guidance. However, these methods are sensitive to visual artifacts which are inevitable during the surgery. In this work, a cross domain feature interaction (CDFI) network is proposed to extract the structural features of lumens, as well as to provide artifact cues to characterize the visual features. To effectively extract the structural and artifact features, the Quadruple Feature Constraints (QFC) module is designed to constrain the intrinsic connections of samples with various imaging-quality. Furthermore, we design a Guided Feature Fusion (GFF) module to supervise the model for adaptive feature fusion based on different types of artifacts. Results show that the features extracted by the proposed method can preserve the structural information of lumen in the presence of large visual variations, bringing much-improved lumen detection accuracy.

Xin You, Yixin Lou, Minghui Zhang et al.

Automatic and precise multi-class vertebrae segmentation from CT images is crucial for various clinical applications. However, due to similar appearances between adjacent vertebrae and the existence of various pathologies, existing single-stage and multi-stage methods suffer from imprecise vertebrae segmentation. Essentially, these methods fail to explicitly impose both contour precision and intra-vertebrae voxel consistency constraints synchronously, resulting in the intra-vertebrae segmentation inconsistency, which refers to multiple label predictions inside a singular vertebra. In this work, we intend to label complete binary masks with sequential indices to address that challenge. Specifically, a contour generation network is proposed based on Structural Low-Rank Descriptors for shape consistency, termed SLoRD. For a structural representation of vertebral contours, we adopt the spherical coordinate system and devise the spherical centroid to calculate contour descriptors. Due to vertebrae's similar appearances, basic contour descriptors can be acquired offline to restore original contours. Therefore, SLoRD leverages these contour priors and explicit shape constraints to facilitate regressed contour points close to vertebral surfaces. Quantitative and qualitative evaluations on VerSe 2019 and 2020 demonstrate the superior performance of our framework over other single-stage and multi-stage state-of-the-art (SOTA) methods. Further, SLoRD is a plug-and-play framework to refine the segmentation inconsistency existing in coarse predictions from other approaches. Source codes are available.

Chuyan Zhang, Kefan Wang, Yun Gu

Low-Rank Adaptation (LoRA) has proven effective in reducing computational costs while maintaining performance comparable to fully fine-tuned foundation models across various tasks. However, its fixed low-rank structure restricts its adaptability in scenarios with substantial domain gaps, where higher ranks are often required to capture domain-specific complexities. Current adaptive LoRA methods attempt to overcome this limitation by dynamically expanding or selectively allocating ranks, but these approaches frequently depend on computationally intensive techniques such as iterative pruning, rank searches, or additional regularization. To address these challenges, we introduce Stable Rank-Guided Low-Rank Adaptation (SR-LoRA), a novel framework that utilizes the stable rank of pre-trained weight matrices as a natural prior for layer-wise rank allocation. By leveraging the stable rank, which reflects the intrinsic dimensionality of the weights, SR-LoRA enables a principled and efficient redistribution of ranks across layers, enhancing adaptability without incurring additional search costs. Empirical evaluations on few-shot tasks with significant domain gaps show that SR-LoRA consistently outperforms recent adaptive LoRA variants, achieving a superior trade-off between performance and efficiency. Our code is available at https://github.com/EndoluminalSurgicalVision-IMR/SR-LoRA.

Chuyan Zhang, Yun Gu

Self-supervised learning (SSL) has achieved remarkable performance in various medical imaging tasks by dint of priors from massive unlabelled data. However, regarding a specific downstream task, there is still a lack of an instruction book on how to select suitable pretext tasks and implementation details throughout the standard ``pretrain-then-finetune'' workflow. In this work, we focus on exploiting the capacity of SSL in terms of four realistic and significant issues: (1) the impact of SSL on imbalanced datasets, (2) the network architecture, (3) the applicability of upstream tasks to downstream tasks and (4) the stacking effect of SSL and common policies for deep learning. We provide a large-scale, in-depth and fine-grained study through extensive experiments on predictive, contrastive, generative and multi-SSL algorithms. Based on the results, we have uncovered several insights. Positively, SSL advances class-imbalanced learning mainly by boosting the performance of the rare class, which is of interest to clinical diagnosis. Unfortunately, SSL offers marginal or even negative returns in some cases, including severely imbalanced and relatively balanced data regimes, as well as combinations with common training policies. Our intriguing findings provide practical guidelines for the usage of SSL in the medical context and highlight the need for developing universal pretext tasks to accommodate diverse application scenarios.

Yang Nan, Xiaodan Xing, Shiyi Wang et al.

Airway-related quantitative imaging biomarkers are crucial for examination, diagnosis, and prognosis in pulmonary diseases. However, the manual delineation of airway trees remains prohibitively time-consuming. While significant efforts have been made towards enhancing airway modelling, current public-available datasets concentrate on lung diseases with moderate morphological variations. The intricate honeycombing patterns present in the lung tissues of fibrotic lung disease patients exacerbate the challenges, often leading to various prediction errors. To address this issue, the 'Airway-Informed Quantitative CT Imaging Biomarker for Fibrotic Lung Disease 2023' (AIIB23) competition was organized in conjunction with the official 2023 International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI). The airway structures were meticulously annotated by three experienced radiologists. Competitors were encouraged to develop automatic airway segmentation models with high robustness and generalization abilities, followed by exploring the most correlated QIB of mortality prediction. A training set of 120 high-resolution computerised tomography (HRCT) scans were publicly released with expert annotations and mortality status. The online validation set incorporated 52 HRCT scans from patients with fibrotic lung disease and the offline test set included 140 cases from fibrosis and COVID-19 patients. The results have shown that the capacity of extracting airway trees from patients with fibrotic lung disease could be enhanced by introducing voxel-wise weighted general union loss and continuity loss. In addition to the competitive image biomarkers for prognosis, a strong airway-derived biomarker (Hazard ratio>1.5, p<0.0001) was revealed for survival prognostication compared with existing clinical measurements, clinician assessment and AI-based biomarkers.

Chenyu Li, Minghui Zhang, Chuyan Zhang et al.

Accurate airway anatomical labeling is crucial for clinicians to identify and navigate complex bronchial structures during bronchoscopy. Automatic airway anatomical labeling is challenging due to significant individual variability and anatomical variations. Previous methods are prone to generate inconsistent predictions, which is harmful for preoperative planning and intraoperative navigation. This paper aims to address these challenges by proposing a novel method that enhances topological consistency and improves the detection of abnormal airway branches. We propose a novel approach incorporating two modules: the Soft Subtree Consistency (SSC) and the Abnormal Branch Saliency (ABS). The SSC module constructs a soft subtree to capture clinically relevant topological relationships, allowing for flexible feature aggregation within and across subtrees. The ABS module facilitates the interaction between node features and prototypes to distinguish abnormal branches, preventing the erroneous aggregation of features between normal and abnormal nodes. Evaluated on a challenging dataset characterized by severe airway distortion and atrophy, our method achieves superior performance compared to state-of-the-art approaches. Specifically, it attains a 91.4% accuracy at the segmental level and an 83.7% accuracy at the subsegmental level, representing a 1.4% increase in subsegmental accuracy and a 3.1% increase in topological consistency. Notably, the method demonstrates reliable performance in cases with disease-induced airway deformities, ensuring consistent and accurate labeling.

Minghui Zhang, Xin You, Hanxiao Zhang et al.

The Circle of Willis (CoW) vessels is critical to connecting major circulations of the brain. The topology of the vascular structure is clinical significance to evaluate the risk, severity of the neuro-vascular diseases. The CoW has two representative angiographic imaging modalities, computed tomography angiography (CTA) and magnetic resonance angiography (MRA). TopCow24 provided 125 paired CTA-MRA dataset for the analysis of CoW. To explore both CTA and MRA images in a unified framework to learn the inherent topology of Cow, we construct the universal dataset via independent intensity preprocess, followed by joint resampling and normarlization. Then, we utilize the topology-aware loss to enhance the topology completeness of the CoW and the discrimination between different classes. A complementary topology-aware refinement is further conducted to enhance the connectivity within the same class. Our method was evaluated on all the three tasks and two modalities, achieving competitive results. In the final test phase of TopCow24 Challenge, we achieved the second place in the CTA-Seg-Task, the third palce in the CTA-Box-Task, the first place in the CTA-Edg-Task, the second place in the MRA-Seg-Task, the third palce in the MRA-Box-Task, the second place in the MRA-Edg-Task.

Junyang Wu, Yun Gu, Guang-Zhong Yang

Robot assisted endoluminal intervention is an emerging technique for both benign and malignant luminal lesions. With vision-based navigation, when combined with pre-operative imaging data as priors, it is possible to recover position and pose of the endoscope without the need of additional sensors. In practice, however, aligning pre-operative and intra-operative domains is complicated by significant texture differences. Although methods such as style transfer can be used to address this issue, they require large datasets from both source and target domains with prolonged training times. This paper proposes an efficient domain transfer method based on stylized Gaussian splatting, only requiring a few of real images (10 images) with very fast training time. Specifically, the transfer process includes two phases. In the first phase, the 3D models reconstructed from CT scans are represented as differential Gaussian point clouds. In the second phase, only color appearance related parameters are optimized to transfer the style and preserve the visual content. A novel structure consistency loss is applied to latent features and depth levels to enhance the stability of the transferred images. Detailed validation was performed to demonstrate the performance advantages of the proposed method compared to that of the current state-of-the-art, highlighting the potential for intra-operative surgical navigation.

Junyang Wu, Fangfang Xie, Jiayuan Sun et al.

Domain adaptation, which bridges the distributions across different modalities, plays a crucial role in multimodal medical image analysis. In endoscopic imaging, combining pre-operative data with intra-operative imaging is important for surgical planning and navigation. However, existing domain adaptation methods are hampered by distribution shift caused by in vivo artifacts, necessitating robust techniques for aligning noisy and artifact abundant patient endoscopic videos with clean virtual images reconstructed from pre-operative tomographic data for pose estimation during intraoperative guidance. This paper presents an artifact-resilient image translation method and an associated benchmark for this purpose. The method incorporates a novel ``local-global'' translation framework and a noise-resilient feature extraction strategy. For the former, it decouples the image translation process into a local step for feature denoising, and a global step for global style transfer. For feature extraction, a new contrastive learning strategy is proposed, which can extract noise-resilient features for establishing robust correspondence across domains. Detailed validation on both public and in-house clinical datasets has been conducted, demonstrating significantly improved performance compared to the current state-of-the-art.

Yuncheng Yang, Chuyan Zhang, Zuopeng Yang et al.

Prompt learning is effective for fine-tuning foundation models to improve their generalization across a variety of downstream tasks. However, the prompts that are independently optimized along a single modality path, may sacrifice the vision-language alignment of pre-trained models in return for improved performance on specific tasks and classes, leading to poorer generalization. In this paper, we first demonstrate that prompt tuning along only one single branch of CLIP (e.g., language or vision) is the reason why the misalignment occurs. Without proper regularization across the learnable parameters in different modalities, prompt learning violates the original pre-training constraints inherent in the two-tower architecture. To address such misalignment, we first propose feature shift, which is defined as the variation of embeddings after introducing the learned prompts, to serve as an explanatory tool. We dive into its relation with generalizability and thereafter propose RESTORE, a multi-modal prompt learning method that exerts explicit constraints on cross-modal consistency. To be more specific, to prevent feature misalignment, a feature shift consistency is introduced to synchronize inter-modal feature shifts by measuring and regularizing the magnitude of discrepancy during prompt tuning. In addition, we propose a "surgery" block to avoid short-cut hacking, where cross-modal misalignment can still be severe if the feature shift of each modality varies drastically at the same rate. It is implemented as feed-forward adapters upon both modalities to alleviate the misalignment problem. Extensive experiments on 15 datasets demonstrate that our method outperforms the state-of-the-art prompt tuning methods without compromising feature alignment.

Minghui Zhang, Xin Yu, Hanxiao Zhang et al.

3D Convolutional Neural Networks (CNNs) have been widely adopted for airway segmentation. The performance of 3D CNNs is greatly influenced by the dataset while the public airway datasets are mainly clean CT scans with coarse annotation, thus difficult to be generalized to noisy CT scans (e.g. COVID-19 CT scans). In this work, we proposed a new dual-stream network to address the variability between the clean domain and noisy domain, which utilizes the clean CT scans and a small amount of labeled noisy CT scans for airway segmentation. We designed two different encoders to extract the transferable clean features and the unique noisy features separately, followed by two independent decoders. Further on, the transferable features are refined by the channel-wise feature recalibration and Signed Distance Map (SDM) regression. The feature recalibration module emphasizes critical features and the SDM pays more attention to the bronchi, which is beneficial to extracting the transferable topological features robust to the coarse labels. Extensive experimental results demonstrated the obvious improvement brought by our proposed method. Compared to other state-of-the-art transfer learning methods, our method accurately segmented more bronchi in the noisy CT scans.

Yulei Qin, Yun Gu, Hanxiao Zhang et al.

To investigate whether the pleurae, airways and vessels surrounding a nodule on non-contrast computed tomography (CT) can discriminate benign and malignant pulmonary nodules. The LIDC-IDRI dataset, one of the largest publicly available CT database, was exploited for study. A total of 1556 nodules from 694 patients were involved in statistical analysis, where nodules with average scorings <3 and >3 were respectively denoted as benign and malignant. Besides, 339 nodules from 113 patients with diagnosis ground-truth were independently evaluated. Computer algorithms were developed to segment pulmonary structures and quantify the distances to pleural surface, airways and vessels, as well as the counting number and normalized volume of airways and vessels near a nodule. Odds ratio (OR) and Chi-square (χ^2) testing were performed to demonstrate the correlation between features of surrounding structures and nodule malignancy. A non-parametric receiver operating characteristic (ROC) analysis was conducted in logistic regression to evaluate discrimination ability of each structure. For benign and malignant groups, the average distances from nodules to pleural surface, airways and vessels are respectively (6.56, 5.19), (37.08, 26.43) and (1.42, 1.07) mm. The correlation between nodules and the counting number of airways and vessels that contact or project towards nodules are respectively (OR=22.96, χ^2=105.04) and (OR=7.06, χ^2=290.11). The correlation between nodules and the volume of airways and vessels are (OR=9.19, χ^2=159.02) and (OR=2.29, χ^2=55.89). The areas-under-curves (AUCs) for pleurae, airways and vessels are respectively 0.5202, 0.6943 and 0.6529. Our results show that malignant nodules are often surrounded by more pulmonary structures compared with benign ones, suggesting that features of these structures could be viewed as lung cancer biomarkers.

Yulei Qin, Hao Zheng, Yun Gu et al.

Training convolutional neural networks (CNNs) for segmentation of pulmonary airway, artery, and vein is challenging due to sparse supervisory signals caused by the severe class imbalance between tubular targets and background. We present a CNNs-based method for accurate airway and artery-vein segmentation in non-contrast computed tomography. It enjoys superior sensitivity to tenuous peripheral bronchioles, arterioles, and venules. The method first uses a feature recalibration module to make the best use of features learned from the neural networks. Spatial information of features is properly integrated to retain relative priority of activated regions, which benefits the subsequent channel-wise recalibration. Then, attention distillation module is introduced to reinforce representation learning of tubular objects. Fine-grained details in high-resolution attention maps are passing down from one layer to its previous layer recursively to enrich context. Anatomy prior of lung context map and distance transform map is designed and incorporated for better artery-vein differentiation capacity. Extensive experiments demonstrated considerable performance gains brought by these components. Compared with state-of-the-art methods, our method extracted much more branches while maintaining competitive overall segmentation performance. Codes and models are available at http://www.pami.sjtu.edu.cn/News/56

Hao Zheng, Yulei Qin, Yun Gu et al.

Automated airway segmentation is a prerequisite for pre-operative diagnosis and intra-operative navigation for pulmonary intervention. Due to the small size and scattered spatial distribution of peripheral bronchi, this is hampered by severe class imbalance between foreground and background regions, which makes it challenging for CNN-based methods to parse distal small airways. In this paper, we demonstrate that this problem is arisen by gradient erosion and dilation of the neighborhood voxels. During back-propagation, if the ratio of the foreground gradient to background gradient is small while the class imbalance is local, the foreground gradients can be eroded by their neighborhoods. This process cumulatively increases the noise information included in the gradient flow from top layers to the bottom ones, limiting the learning of small structures in CNNs. To alleviate this problem, we use group supervision and the corresponding WingsNet to provide complementary gradient flows to enhance the training of shallow layers. To further address the intra-class imbalance between large and small airways, we design a General Union loss function which obviates the impact of airway size by distance-based weights and adaptively tunes the gradient ratio based on the learning process. Extensive experiments on public datasets demonstrate that the proposed method can predict the airway structures with higher accuracy and better morphological completeness than the baselines.

Tianyi Zhang, Yun Gu, Xiaolin Huang et al.

With the popularity of stereo cameras in computer assisted surgery techniques, a second viewpoint would provide additional information in surgery. However, how to effectively access and use stereo information for the super-resolution (SR) purpose is often a challenge. In this paper, we propose a disparity-constrained stereo super-resolution network (DCSSRnet) to simultaneously compute a super-resolved image in a stereo image pair. In particular, we incorporate a disparity-based constraint mechanism into the generation of SR images in a deep neural network framework with an additional atrous parallax-attention modules. Experiment results on laparoscopic images demonstrate that the proposed framework outperforms current SR methods on both quantitative and qualitative evaluations. Our DCSSRnet provides a promising solution on enhancing spatial resolution of stereo image pairs, which will be extremely beneficial for the endoscopic surgery.

Yulei Qin, Mingjian Chen, Hao Zheng et al.

Airway segmentation on CT scans is critical for pulmonary disease diagnosis and endobronchial navigation. Manual extraction of airway requires strenuous efforts due to the complicated structure and various appearance of airway. For automatic airway extraction, convolutional neural networks (CNNs) based methods have recently become the state-of-the-art approach. However, there still remains a challenge for CNNs to perceive the tree-like pattern and comprehend the connectivity of airway. To address this, we propose a voxel-connectivity aware approach named AirwayNet for accurate airway segmentation. By connectivity modeling, conventional binary segmentation task is transformed into 26 tasks of connectivity prediction. Thus, our AirwayNet learns both airway structure and relationship between neighboring voxels. To take advantage of context knowledge, lung distance map and voxel coordinates are fed into AirwayNet as additional semantic information. Compared to existing approaches, AirwayNet achieved superior performance, demonstrating the effectiveness of the network's awareness of voxel connectivity.

Yang Hu, Yun Gu, Jie Yang et al.

In robotic surgery, task automation and learning from demonstration combined with human supervision is an emerging trend for many new surgical robot platforms. One such task is automated anastomosis, which requires bimanual needle handling and suture detection. Due to the complexity of the surgical environment and varying patient anatomies, reliable suture detection is difficult, which is further complicated by occlusion and thread topologies. In this paper, we propose a multi-stage framework for suture thread detection based on deep learning. Fully convolutional neural networks are used to obtain the initial detection and the overlapping status of suture thread, which are later fused with the original image to learn a gradient road map of the thread. Based on the gradient road map, multiple segments of the thread are extracted and linked to form the whole thread using a curvilinear structure detector. Experiments on two different types of sutures demonstrate the accuracy of the proposed framework.

Yun Gu, Guang-Zhong Yang, Jie Yang et al.

Echocardiography plays an important part in diagnostic aid in cardiac diseases. A critical step in echocardiography-aided diagnosis is to extract the standard planes since they tend to provide promising views to present different structures that are benefit to diagnosis. To this end, this paper proposes a spatial-temporal embedding framework to extract the standard view planes from 4D STIC (spatial-temporal image corre- lation) volumes. The proposed method is comprised of three stages, the frame smoothing, spatial-temporal embedding and final classification. In first stage, an L 0 smoothing filter is used to preprocess the frames that removes the noise and preserves the boundary. Then a compact repre- sentation is learned via embedding spatial and temporal features into a latent space in the supervised scheme considering both standard plane information and diagnosis result. In last stage, the learned features are fed into support vector machine to identify the standard plane. We eval- uate the proposed method on a 4D STIC volume dataset with 92 normal cases and 93 abnormal cases in three standard planes. It demonstrates that our method outperforms the baselines in both classification accuracy and computational efficiency.

Wei Liu, Yun Gu, Chunhua Shen et al.

Depth maps captured by modern depth cameras such as Kinect and Time-of-Flight (ToF) are usually contaminated by missing data, noises and suffer from being of low resolution. In this paper, we present a robust method for high-quality restoration of a degraded depth map with the guidance of the corresponding color image. We solve the problem in an energy optimization framework that consists of a novel robust data term and smoothness term. To accommodate not only the noise but also the inconsistency between depth discontinuities and the color edges, we model both the data term and smoothness term with a robust exponential error norm function. We propose to use Iteratively Re-weighted Least Squares (IRLS) methods for efficiently solving the resulting highly non-convex optimization problem. More importantly, we further develop a data-driven adaptive parameter selection scheme to properly determine the parameter in the model. We show that the proposed approach can preserve fine details and sharp depth discontinuities even for a large upsampling factor ($8\times$ for example). Experimental results on both simulated and real datasets demonstrate that the proposed method outperforms recent state-of-the-art methods in coping with the heavy noise, preserving sharp depth discontinuities and suppressing the texture copy artifacts.

Yun Gu, Haoyang Xue, Jie Yang

Learning a hashing function for cross-media search is very desirable due to its low storage cost and fast query speed. However, the data crawled from Internet cannot always guarantee good correspondence among different modalities which affects the learning for hashing function. In this paper, we focus on cross-modal hashing with partially corresponded data. The data without full correspondence are made in use to enhance the hashing performance. The experiments on Wiki and NUS-WIDE datasets demonstrates that the proposed method outperforms some state-of-the-art hashing approaches with fewer correspondence information.