Xu Shuoyu

Huang Jiayan, Ji Zheng, Kuang Jinbo et al.

This manuscript presents an image segmentation algorithm developed for the Cross-Organ and Cross-Scanner Adenocarcinoma Segmentation (COSAS 2024) challenge. We adopted an organ-stratified and scanner-stratified approach to train multiple Upernet-based segmentation models and subsequently ensembled the results. Despite the challenges posed by the varying tumor characteristics across different organs and the differing imaging conditions of various scanners, our method achieved a final test score of 0.7643 for Task 1 and 0.8354 for Task 2. These results demonstrate the adaptability and efficacy of our approach across diverse conditions. Our model's ability to generalize across various datasets underscores its potential for real-world applications.

Ruining Deng, Tianyuan Yao, Yucheng Tang et al.

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney Pathology Image Segmentation (KPIs) Challenge, introducing a dataset that incorporates preclinical rodent models of CKD with over 10,000 annotated glomeruli from 60+ Periodic Acid Schiff (PAS)-stained whole slide images. The challenge includes two tasks, patch-level segmentation and whole slide image segmentation and detection, evaluated using the Dice Similarity Coefficient (DSC) and F1-score. By encouraging innovative segmentation methods that adapt to diverse CKD models and tissue conditions, the KPIs Challenge aims to advance kidney pathology analysis, establish new benchmarks, and enable precise, large-scale quantification for disease research and diagnosis.

JaeWoong Shin, Jeongun Ryu, Aaron Valero Puche et al.

Pathologists routinely alternate between different magnifications when examining Whole-Slide Images, allowing them to evaluate both broad tissue morphology and intricate cellular details to form comprehensive diagnoses. However, existing deep learning-based cell detection models struggle to replicate these behaviors and learn the interdependent semantics between structures at different magnifications. A key barrier in the field is the lack of datasets with multi-scale overlapping cell and tissue annotations. The OCELOT 2023 challenge was initiated to gather insights from the community to validate the hypothesis that understanding cell and tissue (cell-tissue) interactions is crucial for achieving human-level performance, and to accelerate the research in this field. The challenge dataset includes overlapping cell detection and tissue segmentation annotations from six organs, comprising 673 pairs sourced from 306 The Cancer Genome Atlas (TCGA) Whole-Slide Images with hematoxylin and eosin staining, divided into training, validation, and test subsets. Participants presented models that significantly enhanced the understanding of cell-tissue relationships. Top entries achieved up to a 7.99 increase in F1-score on the test set compared to the baseline cell-only model that did not incorporate cell-tissue relationships. This is a substantial improvement in performance over traditional cell-only detection methods, demonstrating the need for incorporating multi-scale semantics into the models. This paper provides a comparative analysis of the methods used by participants, highlighting innovative strategies implemented in the OCELOT 2023 challenge.

Alper Bahcekapili, Duygu Arslan, Umut Ozdemir et al.

Colorectal cancer (CRC) is the third most diagnosed cancer and the second leading cause of cancer-related death worldwide. Accurate histopathological grading of CRC is essential for prognosis and treatment planning but remains a subjective process prone to observer variability and limited by global shortages of trained pathologists. To promote automated and standardized solutions, we organized the ICIP Grand Challenge on Colorectal Cancer Tumor Grading and Segmentation using the publicly available METU CCTGS dataset. The dataset comprises 103 whole-slide images with expert pixel-level annotations for five tissue classes. Participants submitted segmentation masks via Codalab, evaluated using metrics such as macro F-score and mIoU. Among 39 participating teams, six outperformed the Swin Transformer baseline (62.92 F-score). This paper presents an overview of the challenge, dataset, and the top-performing methods