Binbin Hu

Guohui Cai, Ruicheng Zhang, Hongyang He et al.

Pulmonary nodules are critical indicators for the early diagnosis of lung cancer, making their detection essential for timely treatment. However, traditional CT imaging methods suffered from cumbersome procedures, low detection rates, and poor localization accuracy. The subtle differences between pulmonary nodules and surrounding tissues in complex lung CT images, combined with repeated downsampling in feature extraction networks, often lead to missed or false detections of small nodules. Existing methods such as FPN, with its fixed feature fusion and limited receptive field, struggle to effectively overcome these issues. To address these challenges, our paper proposed three key contributions: Firstly, we proposed MSDet, a multiscale attention and receptive field network for detecting tiny pulmonary nodules. Secondly, we proposed the extended receptive domain (ERD) strategy to capture richer contextual information and reduce false positives caused by nodule occlusion. We also proposed the position channel attention mechanism (PCAM) to optimize feature learning and reduce multiscale detection errors, and designed the tiny object detection block (TODB) to enhance the detection of tiny nodules. Lastly, we conducted thorough experiments on the public LUNA16 dataset, achieving state-of-the-art performance, with an mAP improvement of 8.8% over the previous state-of-the-art method YOLOv8. These advancements significantly boosted detection accuracy and reliability, providing a more effective solution for early lung cancer diagnosis. The code will be available at https://github.com/CaiGuoHui123/MSDet

Shengbo Tan, Zeyu Zhang, Ying Cai et al.

Medical imaging segmentation plays a significant role in the automatic recognition and analysis of lesions. State-of-the-art methods, particularly those utilizing transformers, have been prominently adopted in 3D semantic segmentation due to their superior performance in scalability and generalizability. However, plain vision transformers encounter challenges due to their neglect of local features and their high computational complexity. To address these challenges, we introduce three key contributions: Firstly, we proposed SegStitch, an innovative architecture that integrates transformers with denoising ODE blocks. Instead of taking whole 3D volumes as inputs, we adapt axial patches and customize patch-wise queries to ensure semantic consistency. Additionally, we conducted extensive experiments on the BTCV and ACDC datasets, achieving improvements up to 11.48% and 6.71% respectively in mDSC, compared to state-of-the-art methods. Lastly, our proposed method demonstrates outstanding efficiency, reducing the number of parameters by 36.7% and the number of FLOPS by 10.7% compared to UNETR. This advancement holds promising potential for adapting our method to real-world clinical practice. The code will be available at https://github.com/goblin327/SegStitch

Binbin Hu, Zhicheng An, Zhengwei Wu et al.

Estimating individual treatment effects (ITE) from observational data is a critical task across various domains. However, many existing works on ITE estimation overlook the influence of hidden confounders, which remain unobserved at the individual unit level. To address this limitation, researchers have utilized graph neural networks to aggregate neighbors' features to capture the hidden confounders and mitigate confounding bias by minimizing the discrepancy of confounder representations between the treated and control groups. Despite the success of these approaches, practical scenarios often treat all features as confounders and involve substantial differences in feature distributions between the treated and control groups. Confusing the adjustment and confounder and enforcing strict balance on the confounder representations could potentially undermine the effectiveness of outcome prediction. To mitigate this issue, we propose a novel framework called the \textit{Graph Disentangle Causal model} (GDC) to conduct ITE estimation in the network setting. GDC utilizes a causal disentangle module to separate unit features into adjustment and confounder representations. Then we design a graph aggregation module consisting of three distinct graph aggregators to obtain adjustment, confounder, and counterfactual confounder representations. Finally, a causal constraint module is employed to enforce the disentangled representations as true causal factors. The effectiveness of our proposed method is demonstrated by conducting comprehensive experiments on two networked datasets.