Qingtao Pan

Jingxing Zhong, Qingtao Pan, Xuchang Zhou et al.

Breast cancer is one of the most common causes of death among women worldwide, with millions of fatalities annually. Magnetic Resonance Imaging (MRI) can provide various sequences for characterizing tumor morphology and internal patterns, and becomes an effective tool for detection and diagnosis of breast tumors. However, previous deep-learning based tumor segmentation methods have limitations in accurately locating tumor contours due to the challenge of low contrast between cancer and normal areas and blurred boundaries. Leveraging text prompt information holds promise in ameliorating tumor segmentation effect by delineating segmentation regions. Inspired by this, we propose text-guided Breast Tumor Segmentation model (TextBCS) with stage-divided vision-language interaction and evidential learning. Specifically, the proposed stage-divided vision-language interaction facilitates information mutual between visual and text features at each stage of down-sampling, further exerting the advantages of text prompts to assist in locating lesion areas in low contrast scenarios. Moreover, the evidential learning is adopted to quantify the segmentation uncertainty of the model for blurred boundary. It utilizes the variational Dirichlet to characterize the distribution of the segmentation probabilities, addressing the segmentation uncertainties of the boundaries. Extensive experiments validate the superiority of our TextBCS over other segmentation networks, showcasing the best breast tumor segmentation performance on publicly available datasets.

Qingtao Pan, Hongzan Sun, Bing Ji et al.

Vision Language Model (VLM) has great potential to enhance the quality of pseudo labels in semi-supervised spine segmentation by leveraging textual class prompts to generate segmentation map, but no one has studied it yet. Although promising, it lacks explicit constraints to ensure consistency between spine class prompts and spine unit region, resulting in unsatisfactory performance in multi-class segmentation map generation. In this paper, we propose CPS4, the first text-guided semi-supervised spine segmentation network using class prompts to enhance the quality of spine pseudo labels. Specifically, CPS4 is implemented through two training stages. (i) Class-specific consistency constrained VLM pretraining stage: we propose token- and pixel-level attention loss to optimize the consistency between class prompts and spine units, forcing the textual class prompt to be closely coupled with the target spine unit in the semantic space. (ii) Class Prompt driven semi-supervised spine segmentation stage: using the pretrained vision-text encoder, we derive each class-specific binary segmentation map for the unlabeled spine image and integrate them into an unified multi-class segmentation map, improving the quality of the spine pseudo label generated by the semi-supervised spine segmentation network. Experimental results show that our CPS4 achieves superior spine segmentation performance with Dice of 80.44%, only using 5% labeled data on the public spine segmentation dataset, surpassing popular semi-supervised learning and VLM methods. Our code will be available.

Qingtao Pan, Wenhao Qiao, Jingjiao Lou et al.

Semi-supervised medical image segmentation (SSMIS) uses consistency learning to regularize model training, which alleviates the burden of pixel-wise manual annotations. However, it often suffers from error supervision from low-quality pseudo labels. Vision-Language Model (VLM) has great potential to enhance pseudo labels by introducing text prompt guided multimodal supervision information. It nevertheless faces the cross-modal problem: the obtained messages tend to correspond to multiple targets. To address aforementioned problems, we propose a Dual Semantic Similarity-Supervised VLM (DuSSS) for SSMIS. Specifically, 1) a Dual Contrastive Learning (DCL) is designed to improve cross-modal semantic consistency by capturing intrinsic representations within each modality and semantic correlations across modalities. 2) To encourage the learning of multiple semantic correspondences, a Semantic Similarity-Supervision strategy (SSS) is proposed and injected into each contrastive learning process in DCL, supervising semantic similarity via the distribution-based uncertainty levels. Furthermore, a novel VLM-based SSMIS network is designed to compensate for the quality deficiencies of pseudo-labels. It utilizes the pretrained VLM to generate text prompt guided supervision information, refining the pseudo label for better consistency regularization. Experimental results demonstrate that our DuSSS achieves outstanding performance with Dice of 82.52%, 74.61% and 78.03% on three public datasets (QaTa-COV19, BM-Seg and MoNuSeg).