Jun Li

Mingxin Liu, Chengfei Cai, Jun Li et al.

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions. Current methods often employ straightforward fusion strategies for multimodal feature integration, failing to comprehensively capture modality-specific and modality-common interactions, resulting in a limited understanding of multimodal correlations and suboptimal predictive performance. To mitigate these limitations, this paper presents a Multimodal Representation Decoupling Network (MurreNet) to advance cancer survival analysis. Specifically, we first propose a Multimodal Representation Decomposition (MRD) module to explicitly decompose paired input data into modality-specific and modality-shared representations, thereby reducing redundancy between modalities. Furthermore, the disentangled representations are further refined then updated through a novel training regularization strategy that imposes constraints on distributional similarity, difference, and representativeness of modality features. Finally, the augmented multimodal features are integrated into a joint representation via proposed Deep Holistic Orthogonal Fusion (DHOF) strategy. Extensive experiments conducted on six TCGA cancer cohorts demonstrate that our MurreNet achieves state-of-the-art (SOTA) performance in survival prediction.

Congqi Cao, Yajuan Li, Qinyi Lv et al.

Few-shot learning aims to recognize instances from novel classes with few labeled samples, which has great value in research and application. Although there has been a lot of work in this area recently, most of the existing work is based on image classification tasks. Video-based few-shot action recognition has not been explored well and remains challenging: 1) the differences of implementation details among different papers make a fair comparison difficult; 2) the wide variations and misalignment of temporal sequences make the video-level similarity comparison difficult; 3) the scarcity of labeled data makes the optimization difficult. To solve these problems, this paper presents 1) a specific setting to evaluate the performance of few-shot action recognition algorithms; 2) an implicit sequence-alignment algorithm for better video-level similarity comparison; 3) an advanced loss for few-shot learning to optimize pair similarity with limited data. Specifically, we propose a novel few-shot action recognition framework that uses long short-term memory following 3D convolutional layers for sequence modeling and alignment. Circle loss is introduced to maximize the within-class similarity and minimize the between-class similarity flexibly towards a more definite convergence target. Instead of using random or ambiguous experimental settings, we set a concrete criterion analogous to the standard image-based few-shot learning setting for few-shot action recognition evaluation. Extensive experiments on two datasets demonstrate the effectiveness of our proposed method.