Yue Yu

Huaiqian You, Quinn Zhang, Colton J. Ross et al.

We present a data-driven workflow to biological tissue modeling, which aims to predict the displacement field based on digital image correlation (DIC) measurements under unseen loading scenarios, without postulating a specific constitutive model form nor possessing knowledges on the material microstructure. To this end, a material database is constructed from the DIC displacement tracking measurements of multiple biaxial stretching protocols on a porcine tricuspid valve anterior leaflet, with which we build a neural operator learning model. The material response is modeled as a solution operator from the loading to the resultant displacement field, with the material microstructure properties learned implicitly from the data and naturally embedded in the network parameters. Using various combinations of loading protocols, we compare the predictivity of this framework with finite element analysis based on the phenomenological Fung-type model. From in-distribution tests, the predictivity of our approach presents good generalizability to different loading conditions and outperforms the conventional constitutive modeling at approximately one order of magnitude. When tested on out-of-distribution loading ratios, the neural operator learning approach becomes less effective. To improve the generalizability of our framework, we propose a physics-guided neural operator learning model via imposing partial physics knowledge. This method is shown to improve the model's extrapolative performance in the small-deformation regime. Our results demonstrate that with sufficient data coverage and/or guidance from partial physics constraints, the data-driven approach can be a more effective method for modeling biological materials than the traditional constitutive modeling.

Tiantian Fan, Lingjun Liu, Yu Yue et al.

Recently, test-time scaling Large Language Models (LLMs) have demonstrated exceptional reasoning capabilities across scientific and professional tasks by generating long chains-of-thought (CoT). As a crucial component for developing these reasoning models, reinforcement learning (RL), exemplified by Proximal Policy Optimization (PPO) and its variants, allows models to learn through trial and error. However, PPO can be time-consuming due to its inherent on-policy nature, which is further exacerbated by increasing response lengths. In this work, we propose Truncated Proximal Policy Optimization (T-PPO), a novel extension to PPO that improves training efficiency by streamlining policy update and length-restricted response generation. T-PPO mitigates the issue of low hardware utilization, an inherent drawback of fully synchronized long-generation procedures, where resources often sit idle during the waiting periods for complete rollouts. Our contributions are two-folds. First, we propose Extended Generalized Advantage Estimation (EGAE) for advantage estimation derived from incomplete responses while maintaining the integrity of policy learning. Second, we devise a computationally optimized mechanism that allows for the independent optimization of the policy and value models. By selectively filtering prompt and truncated tokens, this mechanism reduces redundant computations and accelerates the training process without sacrificing convergence performance. We demonstrate the effectiveness and efficacy of T-PPO on AIME 2024 with a 32B base model. The experimental results show that T-PPO improves the training efficiency of reasoning LLMs by up to 2.5x and outperforms its existing competitors.

Qi Wang, Hanyang Peng, Yue Yu

Mixture-of-Experts (MoE) models enable scalable performance by activating large parameter sets sparsely, minimizing computational overhead. To mitigate the prohibitive cost of training MoEs from scratch, recent work employs upcycling, reusing a single pre-trained dense model by replicating its feed-forward network (FFN) layers into experts. However, this limits expert diversity, as all experts originate from a single pre-trained dense model. This paper addresses this limitation by constructing powerful MoE models using experts sourced from multiple identically-architected but disparate pre-trained models (e.g., Qwen2.5-Coder and Qwen2). A key challenge lies in the fact that these source models occupy disparate, dissonant regions of the parameter space, making direct upcycling prone to severe performance degradation. To overcome this, we propose Symphony-MoE, a novel two-stage framework designed to harmonize these models into a single, coherent expert mixture. First, we establish this harmony in a training-free manner: we construct a shared backbone via a layer-aware fusion strategy and, crucially, alleviate parameter misalignment among experts using activation-based functional alignment. Subsequently, a stage of post-training coordinates the entire architecture. Experiments demonstrate that our method successfully integrates experts from heterogeneous sources, achieving an MoE model that significantly surpasses baselines in multi-domain tasks and out-of-distribution generalization.