Neeraj Kumar

Xiang Li, Yazhou Zhang, Prayag Tiwari et al.

Emotion recognition technology through analyzing the EEG signal is currently an essential concept in Artificial Intelligence and holds great potential in emotional health care, human-computer interaction, multimedia content recommendation, etc. Though there have been several works devoted to reviewing EEG-based emotion recognition, the content of these reviews needs to be updated. In addition, those works are either fragmented in content or only focus on specific techniques adopted in this area but neglect the holistic perspective of the entire technical routes. Hence, in this paper, we review from the perspective of researchers who try to take the first step on this topic. We review the recent representative works in the EEG-based emotion recognition research and provide a tutorial to guide the researchers to start from the beginning. The scientific basis of EEG-based emotion recognition in the psychological and physiological levels is introduced. Further, we categorize these reviewed works into different technical routes and illustrate the theoretical basis and the research motivation, which will help the readers better understand why those techniques are studied and employed. At last, existing challenges and future investigations are also discussed in this paper, which guides the researchers to decide potential future research directions.

Jamie C. Overbeek, Alexander Partin, Thomas S. Brettin et al.

Cancer drug response prediction (DRP) models present a promising approach towards precision oncology, tailoring treatments to individual patient profiles. While deep learning (DL) methods have shown great potential in this area, models that can be successfully translated into clinical practice and shed light on the molecular mechanisms underlying treatment response will likely emerge from collaborative research efforts. This highlights the need for reusable and adaptable models that can be improved and tested by the wider scientific community. In this study, we present a scoring system for assessing the reusability of prediction DRP models, and apply it to 17 peer-reviewed DL-based DRP models. As part of the IMPROVE (Innovative Methodologies and New Data for Predictive Oncology Model Evaluation) project, which aims to develop methods for systematic evaluation and comparison DL models across scientific domains, we analyzed these 17 DRP models focusing on three key categories: software environment, code modularity, and data availability and preprocessing. While not the primary focus, we also attempted to reproduce key performance metrics to verify model behavior and adaptability. Our assessment of 17 DRP models reveals both strengths and shortcomings in model reusability. To promote rigorous practices and open-source sharing, we offer recommendations for developing and sharing prediction models. Following these recommendations can address many of the issues identified in this study, improving model reusability without adding significant burdens on researchers. This work offers the first comprehensive assessment of reusability and reproducibility across diverse DRP models, providing insights into current model sharing practices and promoting standards within the DRP and broader AI-enabled scientific research community.

Nadia Mumtaz, Naveed Ejaz, Shabana Habib et al.

The Big Video Data generated in today's smart cities has raised concerns from its purposeful usage perspective, where surveillance cameras, among many others are the most prominent resources to contribute to the huge volumes of data, making its automated analysis a difficult task in terms of computation and preciseness. Violence Detection (VD), broadly plunging under Action and Activity recognition domain, is used to analyze Big Video data for anomalous actions incurred due to humans. The VD literature is traditionally based on manually engineered features, though advancements to deep learning based standalone models are developed for real-time VD analysis. This paper focuses on overview of deep sequence learning approaches along with localization strategies of the detected violence. This overview also dives into the initial image processing and machine learning-based VD literature and their possible advantages such as efficiency against the current complex models. Furthermore,the datasets are discussed, to provide an analysis of the current models, explaining their pros and cons with future directions in VD domain derived from an in-depth analysis of the previous methods.

Andrew D. McNaughton, Mridula S. Bontha, Carter R. Knutson et al.

Efficient design and discovery of target-driven molecules is a critical step in facilitating lead optimization in drug discovery. Current approaches to develop molecules for a target protein are intuition-driven, hampered by slow iterative design-test cycles due to computational challenges in utilizing 3D structural data, and ultimately limited by the expertise of the chemist - leading to bottlenecks in molecular design. In this contribution, we propose a novel framework, called 3D-MolGNN$_{RL}$, coupling reinforcement learning (RL) to a deep generative model based on 3D-Scaffold to generate target candidates specific to a protein building up atom by atom from the starting core scaffold. 3D-MolGNN$_{RL}$ provides an efficient way to optimize key features by multi-objective reward function within a protein pocket using parallel graph neural network models. The agent learns to build molecules in 3D space while optimizing the activity, binding affinity, potency, and synthetic accessibility of the candidates generated for infectious disease protein targets. Our approach can serve as an interpretable artificial intelligence (AI) tool for lead optimization with optimized activity, potency, and biophysical properties.

Andrew D. McNaughton, Gautham Ramalaxmi, Agustin Kruel et al.

Large language models (LLMs) have shown remarkable potential in various domains, but they often lack the ability to access and reason over domain-specific knowledge and tools. In this paper, we introduced CACTUS (Chemistry Agent Connecting Tool-Usage to Science), an LLM-based agent that integrates cheminformatics tools to enable advanced reasoning and problem-solving in chemistry and molecular discovery. We evaluate the performance of CACTUS using a diverse set of open-source LLMs, including Gemma-7b, Falcon-7b, MPT-7b, Llama2-7b, and Mistral-7b, on a benchmark of thousands of chemistry questions. Our results demonstrate that CACTUS significantly outperforms baseline LLMs, with the Gemma-7b and Mistral-7b models achieving the highest accuracy regardless of the prompting strategy used. Moreover, we explore the impact of domain-specific prompting and hardware configurations on model performance, highlighting the importance of prompt engineering and the potential for deploying smaller models on consumer-grade hardware without significant loss in accuracy. By combining the cognitive capabilities of open-source LLMs with domain-specific tools, CACTUS can assist researchers in tasks such as molecular property prediction, similarity searching, and drug-likeness assessment. Furthermore, CACTUS represents a significant milestone in the field of cheminformatics, offering an adaptable tool for researchers engaged in chemistry and molecular discovery. By integrating the strengths of open-source LLMs with domain-specific tools, CACTUS has the potential to accelerate scientific advancement and unlock new frontiers in the exploration of novel, effective, and safe therapeutic candidates, catalysts, and materials. Moreover, CACTUS's ability to integrate with automated experimentation platforms and make data-driven decisions in real time opens up new possibilities for autonomous discovery.

Atharvan Dogra, Deeksha Varshney, Ashwin Kalyan et al.

The generation of effective latent representations and their subsequent refinement to incorporate precise information is an essential prerequisite for Vision-Language Understanding (VLU) tasks such as Video Question Answering (VQA). However, most existing methods for VLU focus on sparsely sampling or fine-graining the input information (e.g., sampling a sparse set of frames or text tokens), or adding external knowledge. We present a novel "DRAX: Distraction Removal and Attended Cross-Alignment" method to rid our cross-modal representations of distractors in the latent space. We do not exclusively confine the perception of any input information from various modalities but instead use an attention-guided distraction removal method to increase focus on task-relevant information in latent embeddings. DRAX also ensures semantic alignment of embeddings during cross-modal fusions. We evaluate our approach on a challenging benchmark (SUTD-TrafficQA dataset), testing the framework's abilities for feature and event queries, temporal relation understanding, forecasting, hypothesis, and causal analysis through extensive experiments.

Carter Knutson, Gihan Panapitiya, Rohith Varikoti et al.

Neural Networks (GNNs) have revolutionized the molecular discovery to understand patterns and identify unknown features that can aid in predicting biophysical properties and protein-ligand interactions. However, current models typically rely on 2-dimensional molecular representations as input, and while utilization of 2\3- dimensional structural data has gained deserved traction in recent years as many of these models are still limited to static graph representations. We propose a novel approach based on the transformer model utilizing GNNs for characterizing dynamic features of protein-ligand interactions. Our message passing transformer pre-trains on a set of molecular dynamic data based off of physics-based simulations to learn coordinate construction and make binding probability and affinity predictions as a downstream task. Through extensive testing we compare our results with the existing models, our MDA-PLI model was able to outperform the molecular interaction prediction models with an RMSE of 1.2958. The geometric encodings enabled by our transformer architecture and the addition of time series data add a new dimensionality to this form of research.

Agustin Kruel, Andrew D. McNaughton, Neeraj Kumar

In therapeutic design, balancing various physiochemical properties is crucial for molecule development, similar to how Multiparameter Optimization (MPO) evaluates multiple variables to meet a primary goal. While many molecular features can now be predicted using \textit{in silico} methods, aiding early drug development, the vast data generated from high throughput virtual screening challenges the practicality of traditional MPO approaches. Addressing this, we introduce a scaffold focused graph-based Markov chain Monte Carlo framework (ScaMARS) built to generate molecules with optimal properties. This innovative framework is capable of self-training and handling a wider array of properties, sampling different chemical spaces according to the starting scaffold. The benchmark analysis on several properties shows that ScaMARS has a diversity score of 84.6\% and has a much higher success rate of 99.5\% compared to conditional models. The integration of new features into MPO significantly enhances its adaptability and effectiveness in therapeutic design, facilitating the discovery of candidates that efficiently optimize multiple properties.

Shivraj Singh Bhatti, Aryan Yadav, Mitali Monga et al.

The classification of harmful brain activities, such as seizures and periodic discharges, play a vital role in neurocritical care, enabling timely diagnosis and intervention. Electroencephalography (EEG) provides a non-invasive method for monitoring brain activity, but the manual interpretation of EEG signals are time-consuming and rely heavily on expert judgment. This study presents a comparative analysis of deep learning architectures, including Convolutional Neural Networks (CNNs), Vision Transformers (ViTs), and EEGNet, applied to the classification of harmful brain activities using both raw EEG data and time-frequency representations generated through Continuous Wavelet Transform (CWT). We evaluate the performance of these models use multimodal data representations, including high-resolution spectrograms and waveform data, and introduce a multi-stage training strategy to improve model robustness. Our results show that training strategies, data preprocessing, and augmentation techniques are as critical to model success as architecture choice, with multi-stage TinyViT and EfficientNet demonstrating superior performance. The findings underscore the importance of robust training regimes in achieving accurate and efficient EEG classification, providing valuable insights for deploying AI models in clinical practice.

Peiying Zhang, Xue Pang, Neeraj Kumar et al.

With the advent of the Internet of things (IoT) era, more and more devices are connected to the IoT. Under the traditional cloud-thing centralized management mode, the transmission of massive data is facing many difficulties, and the reliability of data is difficult to be guaranteed. As emerging technologies, blockchain technology and edge computing (EC) technology have attracted the attention of academia in improving the reliability, privacy and invariability of IoT technology. In this paper, we combine the characteristics of the EC and blockchain to ensure the reliability of data transmission in the IoT. First of all, we propose a data transmission mechanism based on blockchain, which uses the distributed architecture of blockchain to ensure that the data is not tampered with; secondly, we introduce the three-tier structure in the architecture in turn; finally, we introduce the four working steps of the mechanism, which are similar to the working mechanism of blockchain. In the end, the simulation results show that the proposed scheme can ensure the reliability of data transmission in the Internet of things to a great extent.

Peiying Zhang, Chao Wang, Gagangeet Singh Aujla et al.

The wireless network communication mode represented by the Internet of vehicles (IoV) has been widely used. However, due to the limitations of traditional network architecture, resource scheduling in wireless network environment is still facing great challenges. This paper focuses on the allocation of bandwidth resources in the virtual network environment. This paper proposes a bandwidth aware multi domain virtual network embedding algorithm (BA-VNE). The algorithm is mainly aimed at the problem that users need a lot of bandwidth in wireless communication mode, and solves the problem of bandwidth resource allocation from the perspective of virtual network embedding (VNE). In order to improve the performance of the algorithm, we introduce particle swarm optimization (PSO) algorithm to optimize the performance of the algorithm. In order to verify the effectiveness of the algorithm, we have carried out simulation experiments from link bandwidth, mapping cost and virtual network request (VNR) acceptance rate. The final results show that the proposed algorithm is better than other representative algorithms in the above indicators.

Peiying Zhang, Chao Wang, Neeraj Kumar et al.

Traditional ground wireless communication networks cannot provide high-quality services for artificial intelligence (AI) applications such as intelligent transportation systems (ITS) due to deployment, coverage and capacity issues. The space-air-ground integrated network (SAGIN) has become a research focus in the industry. Compared with traditional wireless communication networks, SAGIN is more flexible and reliable, and it has wider coverage and higher quality of seamless connection. However, due to its inherent heterogeneity, time-varying and self-organizing characteristics, the deployment and use of SAGIN still faces huge challenges, among which the orchestration of heterogeneous resources is a key issue. Based on virtual network architecture and deep reinforcement learning (DRL), we model SAGIN's heterogeneous resource orchestration as a multi-domain virtual network embedding (VNE) problem, and propose a SAGIN cross-domain VNE algorithm. We model the different network segments of SAGIN, and set the network attributes according to the actual situation of SAGIN and user needs. In DRL, the agent is acted by a five-layer policy network. We build a feature matrix based on network attributes extracted from SAGIN and use it as the agent training environment. Through training, the probability of each underlying node being embedded can be derived. In test phase, we complete the embedding process of virtual nodes and links in turn based on this probability. Finally, we verify the effectiveness of the algorithm from both training and testing.

Peiying Zhang, Chao Wang, Neeraj Kumar et al.

Network virtualization (NV) is a technology with broad application prospects. Virtual network embedding (VNE) is the core orientation of VN, which aims to provide more flexible underlying physical resource allocation for user function requests. The classical VNE problem is usually solved by heuristic method, but this method often limits the flexibility of the algorithm and ignores the time limit. In addition, the partition autonomy of physical domain and the dynamic characteristics of virtual network request (VNR) also increase the difficulty of VNE. This paper proposed a new type of VNE algorithm, which applied reinforcement learning (RL) and graph neural network (GNN) theory to the algorithm, especially the combination of graph convolutional neural network (GCNN) and RL algorithm. Based on a self-defined fitness matrix and fitness value, we set up the objective function of the algorithm implementation, realized an efficient dynamic VNE algorithm, and effectively reduced the degree of resource fragmentation. Finally, we used comparison algorithms to evaluate the proposed method. Simulation experiments verified that the dynamic VNE algorithm based on RL and GCNN has good basic VNE characteristics. By changing the resource attributes of physical network and virtual network, it can be proved that the algorithm has good flexibility.

Peiying Zhang, Chao Wang, Chunxiao Jiang et al.

The development of Intelligent Cyber-Physical Systems (ICPSs) in virtual network environment is facing severe challenges. On the one hand, the Internet of things (IoT) based on ICPSs construction needs a large amount of reasonable network resources support. On the other hand, ICPSs are facing severe network security problems. The integration of ICPSs and network virtualization (NV) can provide more efficient network resource support and security guarantees for IoT users. Based on the above two problems faced by ICPSs, we propose a virtual network embedded (VNE) algorithm with computing, storage resources and security constraints to ensure the rationality and security of resource allocation in ICPSs. In particular, we use reinforcement learning (RL) method as a means to improve algorithm performance. We extract the important attribute characteristics of underlying network as the training environment of RL agent. Agent can derive the optimal node embedding strategy through training, so as to meet the requirements of ICPSs for resource management and security. The embedding of virtual links is based on the breadth first search (BFS) strategy. Therefore, this is a comprehensive two-stage RL-VNE algorithm considering the constraints of computing, storage and security three-dimensional resources. Finally, we design a large number of simulation experiments from the perspective of typical indicators of VNE algorithms. The experimental results effectively illustrate the effectiveness of the algorithm in the application of ICPSs.

Carter Knutson, Mridula Bontha, Jenna A. Bilbrey et al.

Protein-ligand interactions (PLIs) are fundamental to biochemical research and their identification is crucial for estimating biophysical and biochemical properties for rational therapeutic design. Currently, experimental characterization of these properties is the most accurate method, however, this is very time-consuming and labor-intensive. A number of computational methods have been developed in this context but most of the existing PLI prediction heavily depends on 2D protein sequence data. Here, we present a novel parallel graph neural network (GNN) to integrate knowledge representation and reasoning for PLI prediction to perform deep learning guided by expert knowledge and informed by 3D structural data. We develop two distinct GNN architectures, GNNF is the base implementation that employs distinct featurization to enhance domain-awareness, while GNNP is a novel implementation that can predict with no prior knowledge of the intermolecular interactions. The comprehensive evaluation demonstrated that GNN can successfully capture the binary interactions between ligand and proteins 3D structure with 0.979 test accuracy for GNNF and 0.958 for GNNP for predicting activity of a protein-ligand complex. These models are further adapted for regression tasks to predict experimental binding affinities and pIC50 is crucial for drugs potency and efficacy. We achieve a Pearson correlation coefficient of 0.66 and 0.65 on experimental affinity and 0.50 and 0.51 on pIC50 with GNNF and GNNP, respectively, outperforming similar 2D sequence-based models. Our method can serve as an interpretable and explainable artificial intelligence (AI) tool for predicted activity, potency, and biophysical properties of lead candidates. To this end, we show the utility of GNNP on SARS-Cov-2 protein targets by screening a large compound library and comparing our prediction with the experimentally measured data.

Luca Pion-Tonachini, Kristofer Bouchard, Hector Garcia Martin et al.

We outline emerging opportunities and challenges to enhance the utility of AI for scientific discovery. The distinct goals of AI for industry versus the goals of AI for science create tension between identifying patterns in data versus discovering patterns in the world from data. If we address the fundamental challenges associated with "bridging the gap" between domain-driven scientific models and data-driven AI learning machines, then we expect that these AI models can transform hypothesis generation, scientific discovery, and the scientific process itself.

Neeraj Kumar, Siddhansh Narang

There has been a remarkable progress in learning a model which could recognise novel classes with only a few labeled examples in the last few years. Few-shot learning (FSL) for action recognition is a challenging task of recognising novel action categories which are represented by few instances in the training data. We propose a novel variational inference based architectural framework (HF-AR) for few shot activity recognition. Our framework leverages volume-preserving Householder Flow to learn a flexible posterior distribution of the novel classes. This results in better performance as compared to state-of-the-art few shot approaches for human activity recognition. approach consists of base model and an adapter model. Our architecture consists of a base model and an adapter model. The base model is trained on seen classes and it computes an embedding that represent the spatial and temporal insights extracted from the input video, e.g. combination of Resnet-152 and LSTM based encoder-decoder model. The adapter model applies a series of Householder transformations to compute a flexible posterior distribution that lends higher accuracy in the few shot approach. Extensive experiments on three well-known datasets: UCF101, HMDB51 and Something-Something-V2, demonstrate similar or better performance on 1-shot and 5-shot classification as compared to state-of-the-art few shot approaches that use only RGB frame sequence as input. To the best of our knowledge, we are the first to explore variational inference along with householder transformations to capture the full rank covariance matrix of posterior distribution, for few shot learning in activity recognition.

Waqas Ahmed, Amir Rasool, Neeraj Kumar et al.

Cash payment is still king in several markets, accounting for more than 90\ of the payments in almost all the developing countries. The usage of mobile phones is pretty ordinary in this present era. Mobile phones have become an inseparable friend for many users, serving much more than just communication tools. Every subsequent person is heavily relying on them due to multifaceted usage and affordability. Every person wants to manage his/her daily transactions and related issues by using his/her mobile phone. With the rise and advancements of mobile-specific security, threats are evolving as well. In this paper, we provide a survey of various security models for mobile phones. We explore multiple proposed models of the mobile payment system (MPS), their technologies and comparisons, payment methods, different security mechanisms involved in MPS, and provide analysis of the encryption technologies, authentication methods, and firewall in MPS. We also present current challenges and future directions of mobile phone security.

Longling Zhang, Bochen Shen, Ahmed Barnawi et al.

Existing deep learning technologies generally learn the features of chest X-ray data generated by Generative Adversarial Networks (GAN) to diagnose COVID-19 pneumonia. However, the above methods have a critical challenge: data privacy. GAN will leak the semantic information of the training data which can be used to reconstruct the training samples by attackers, thereby this method will leak the privacy of the patient. Furthermore, for this reason that is the limitation of the training data sample, different hospitals jointly train the model through data sharing, which will also cause the privacy leakage. To solve this problem, we adopt the Federated Learning (FL) frame-work which is a new technique being used to protect the data privacy. Under the FL framework and Differentially Private thinking, we propose a FederatedDifferentially Private Generative Adversarial Network (FedDPGAN) to detectCOVID-19 pneumonia for sustainable smart cities. Specifically, we use DP-GAN to privately generate diverse patient data in which differential privacy technology is introduced to make sure the privacy protection of the semantic information of training dataset. Furthermore, we leverage FL to allow hospitals to collaboratively train COVID-19 models without sharing the original data. Under Independent and Identically Distributed (IID) and non-IID settings, The evaluation of the proposed model is on three types of chest X-ray (CXR) images dataset (COVID-19, normal, and normal pneumonia). A large number of the truthful reports make the verification of our model can effectively diagnose COVID-19 without compromising privacy.

Neeraj Kumar, Srishti Goel, Ankur Narang et al.

We consider the challenging problem of audio to animated video generation. We propose a novel method OneShotAu2AV to generate an animated video of arbitrary length using an audio clip and a single unseen image of a person as an input. The proposed method consists of two stages. In the first stage, OneShotAu2AV generates the talking-head video in the human domain given an audio and a person's image. In the second stage, the talking-head video from the human domain is converted to the animated domain. The model architecture of the first stage consists of spatially adaptive normalization based multi-level generator and multiple multilevel discriminators along with multiple adversarial and non-adversarial losses. The second stage leverages attention based normalization driven GAN architecture along with temporal predictor based recycle loss and blink loss coupled with lipsync loss, for unsupervised generation of animated video. In our approach, the input audio clip is not restricted to any specific language, which gives the method multilingual applicability. OneShotAu2AV can generate animated videos that have: (a) lip movements that are in sync with the audio, (b) natural facial expressions such as blinks and eyebrow movements, (c) head movements. Experimental evaluation demonstrates superior performance of OneShotAu2AV as compared to U-GAT-IT and RecycleGan on multiple quantitative metrics including KID(Kernel Inception Distance), Word error rate, blinks/sec

Neeraj Kumar, Srishti Goel, Ankur Narang et al.

Speech-driven facial video generation has been a complex problem due to its multi-modal aspects namely audio and video domain. The audio comprises lots of underlying features such as expression, pitch, loudness, prosody(speaking style) and facial video has lots of variability in terms of head movement, eye blinks, lip synchronization and movements of various facial action units along with temporal smoothness. Synthesizing highly expressive facial videos from the audio input and static image is still a challenging task for generative adversarial networks. In this paper, we propose a multi-modal adaptive normalization(MAN) based architecture to synthesize a talking person video of arbitrary length using as input: an audio signal and a single image of a person. The architecture uses the multi-modal adaptive normalization, keypoint heatmap predictor, optical flow predictor and class activation map[58] based layers to learn movements of expressive facial components and hence generates a highly expressive talking-head video of the given person. The multi-modal adaptive normalization uses the various features of audio and video such as Mel spectrogram, pitch, energy from audio signals and predicted keypoint heatmap/optical flow and a single image to learn the respective affine parameters to generate highly expressive video. Experimental evaluation demonstrates superior performance of the proposed method as compared to Realistic Speech-Driven Facial Animation with GANs(RSDGAN) [53], Speech2Vid [10], and other approaches, on multiple quantitative metrics including: SSIM (structural similarity index), PSNR (peak signal to noise ratio), CPBD (image sharpness), WER(word error rate), blinks/sec and LMD(landmark distance). Further, qualitative evaluation and Online Turing tests demonstrate the efficacy of our approach.

Mohammed Hassanin, Ibrahim Radwan, Nour Moustafa et al.

Deep Neural Network (DNN) models have vulnerabilities related to security concerns, with attackers usually employing complex hacking techniques to expose their structures. Data poisoning-enabled perturbation attacks are complex adversarial ones that inject false data into models. They negatively impact the learning process, with no benefit to deeper networks, as they degrade a model's accuracy and convergence rates. In this paper, we propose an attack-agnostic-based defense method for mitigating their influence. In it, a Defensive Feature Layer (DFL) is integrated with a well-known DNN architecture which assists in neutralizing the effects of illegitimate perturbation samples in the feature space. To boost the robustness and trustworthiness of this method for correctly classifying attacked input samples, we regularize the hidden space of a trained model with a discriminative loss function called Polarized Contrastive Loss (PCL). It improves discrimination among samples in different classes and maintains the resemblance of those in the same class. Also, we integrate a DFL and PCL in a compact model for defending against data poisoning attacks. This method is trained and tested using the CIFAR-10 and MNIST datasets with data poisoning-enabled perturbation attacks, with the experimental results revealing its excellent performance compared with those of recent peer techniques.

Thippa Reddy Gadekallu, Manoj M K, Sivarama Krishnan S et al.

The application of machine learning (ML) algorithms are massively scaling-up due to rapid digitization and emergence of new tecnologies like Internet of Things (IoT). In today's digital era, we can find ML algorithms being applied in the areas of healthcare, IoT, engineering, finance and so on. However, all these algorithms need to be trained in order to predict/solve a particular problem. There is high possibility of tampering the training datasets and produce biased results. Hence, in this article, we have proposed blockchain based solution to secure the datasets generated from IoT devices for E-Health applications. The proposed blockchain based solution uses using private cloud to tackle the aforementioned issue. For evaluation, we have developed a system that can be used by dataset owners to secure their data.

Ashish Rana, Taranveer Singh, Harpreet Singh et al.

The big problem for neural network models which are trained to count instances is that whenever test range goes high training range generalization error increases i.e. they are not good generalizers outside training range. Consider the case of automating cell counting process where more dense images with higher cell counts are commonly encountered as compared to images used in training data. By making better predictions for higher ranges of cell count we are aiming to create better generalization systems for cell counting. With architecture proposal of neural arithmetic logic units (NALU) for arithmetic operations, task of counting has become feasible for higher numeric ranges which were not included in training data with better accuracy. As a part of our study we used these units and different other activation functions for learning cell counting task with two different architectures namely Fully Convolutional Regression Network and U-Net. These numerically biased units are added in the form of residual concatenated layers to original architectures and a comparative experimental study is done with these newly proposed changes. This comparative study is described in terms of optimizing regression loss problem from these models trained with extensive data augmentation techniques. We were able to achieve better results in our experiments of cell counting tasks with introduction of these numerically biased units to already existing architectures in the form of residual layer concatenation connections. Our results confirm that above stated numerically biased units does help models to learn numeric quantities for better generalization results.