Min He

Jiaxu Zheng, Meiman He, Xuhui Tang et al.

Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging and MR-only radiation therapy. These integrated approaches are critically dependent on accurate estimation of radiation attenuation, which is typically facilitated by synthesizing Computed Tomography (CT) images from MR scans to generate attenuation maps. However, existing MR-to-CT synthesis methods for whole-body imaging often suffer from poor spatial alignment between the generated CT and input MR images, and insufficient image quality for reliable use in downstream clinical tasks. In this paper, we present a novel 3D Wavelet Latent Diffusion Model (3D-WLDM) that addresses these limitations by performing modality translation in a learned latent space. By incorporating a Wavelet Residual Module into the encoder-decoder architecture, we enhance the capture and reconstruction of fine-scale features across image and latent spaces. To preserve anatomical integrity during the diffusion process, we disentangle structural and modality-specific characteristics and anchor the structural component to prevent warping. We also introduce a Dual Skip Connection Attention mechanism within the diffusion model, enabling the generation of high-resolution CT images with improved representation of bony structures and soft-tissue contrast.

Yuan Yuan, Muyu He, Muhammad Adil Shahid et al.

This paper introduces TurnaboutLLM, a novel framework and dataset for evaluating the deductive reasoning abilities of Large Language Models (LLMs) by leveraging the interactive gameplay of detective games Ace Attorney and Danganronpa. The framework tasks LLMs with identifying contradictions between testimonies and evidences within long narrative contexts, a challenging task due to the large answer space and diverse reasoning types presented by its questions. We evaluate twelve state-of-the-art LLMs on the dataset, hinting at limitations of popular strategies for enhancing deductive reasoning such as extensive thinking and Chain-of-Thought prompting. The results also suggest varying effects of context size, the number of reasoning step and answer space size on model performance. Overall, TurnaboutLLM presents a substantial challenge for LLMs' deductive reasoning abilities in complex, narrative-rich environments.