CUNSB-RFIE: Context-aware Unpaired Neural Schrödinger Bridge in Retinal Fundus Image EnhancementXuanzhao Dong, Vamsi Krishna Vasa, Wenhui Zhu et al.
Retinal fundus photography is significant in diagnosing and monitoring retinal diseases. However, systemic imperfections and operator/patient-related factors can hinder the acquisition of high-quality retinal images. Previous efforts in retinal image enhancement primarily relied on GANs, which are limited by the trade-off between training stability and output diversity. In contrast, the Schrödinger Bridge (SB), offers a more stable solution by utilizing Optimal Transport (OT) theory to model a stochastic differential equation (SDE) between two arbitrary distributions. This allows SB to effectively transform low-quality retinal images into their high-quality counterparts. In this work, we leverage the SB framework to propose an image-to-image translation pipeline for retinal image enhancement. Additionally, previous methods often fail to capture fine structural details, such as blood vessels. To address this, we enhance our pipeline by introducing Dynamic Snake Convolution, whose tortuous receptive field can better preserve tubular structures. We name the resulting retinal fundus image enhancement framework the Context-aware Unpaired Neural Schrödinger Bridge (CUNSB-RFIE). To the best of our knowledge, this is the first endeavor to use the SB approach for retinal image enhancement. Experimental results on a large-scale dataset demonstrate the advantage of the proposed method compared to several state-of-the-art supervised and unsupervised methods in terms of image quality and performance on downstream tasks.The code is available at https://github.com/Retinal-Research/CUNSB-RFIE .
40.8CLMar 31, 2025Code
Crossing the Reward Bridge: Expanding RL with Verifiable Rewards Across Diverse DomainsYi Su, Dian Yu, Linfeng Song et al.
Reinforcement learning with verifiable rewards (RLVR) has demonstrated significant success in enhancing mathematical reasoning and coding performance of large language models (LLMs), especially when structured reference answers are accessible for verification. However, its extension to broader, less structured domains remains unexplored. In this work, we investigate the effectiveness and scalability of RLVR across diverse real-world domains including medicine, chemistry, psychology, economics, and education, where structured reference answers are typically unavailable. We reveal that binary verification judgments on broad-domain tasks exhibit high consistency across various LLMs provided expert-written reference answers exist. Motivated by this finding, we utilize a generative scoring technique that yields soft, model-based reward signals to overcome limitations posed by binary verifications, especially in free-form, unstructured answer scenarios. We further demonstrate the feasibility of training cross-domain generative reward models using relatively small (7B) LLMs without the need for extensive domain-specific annotation. Through comprehensive experiments, our RLVR framework establishes clear performance gains, significantly outperforming state-of-the-art open-source aligned models such as Qwen2.5-72B and DeepSeek-R1-Distill-Qwen-32B across domains in free-form settings. Our approach notably enhances the robustness, flexibility, and scalability of RLVR, representing a substantial step towards practical reinforcement learning applications in complex, noisy-label scenarios.
TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image EnhancementXuanzhao Dong, Wenhui Zhu, Xin Li et al.
Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to preserve the complex topological information of blood vessels, resulting in spurious or missing vessel structures. The persistence diagram, which captures topological features based on the persistence of topological structures under different filtrations, provides a promising way to represent the structure information. In this work, we propose a topology-preserving training paradigm that regularizes blood vessel structures by minimizing the differences of persistence diagrams. We call the resulting framework Topology Preserving Optimal Transport (TPOT). Experimental results on a large-scale dataset demonstrate the superiority of the proposed method compared to several state-of-the-art supervised and unsupervised techniques, both in terms of image quality and performance in the downstream blood vessel segmentation task. The code is available at https://github.com/Retinal-Research/TPOT.
EyeBench: A Call for More Rigorous Evaluation of Retinal Image EnhancementWenhui Zhu, Xuanzhao Dong, Xin Li et al.
Over the past decade, generative models have achieved significant success in enhancement fundus images.However, the evaluation of these models still presents a considerable challenge. A comprehensive evaluation benchmark for fundus image enhancement is indispensable for three main reasons: 1) The existing denoising metrics (e.g., PSNR, SSIM) are hardly to extend to downstream real-world clinical research (e.g., Vessel morphology consistency). 2) There is a lack of comprehensive evaluation for both paired and unpaired enhancement methods, along with the need for expert protocols to accurately assess clinical value. 3) An ideal evaluation system should provide insights to inform future developments of fundus image enhancement. To this end, we propose a novel comprehensive benchmark, EyeBench, to provide insights that align enhancement models with clinical needs, offering a foundation for future work to improve the clinical relevance and applicability of generative models for fundus image enhancement. EyeBench has three appealing properties: 1) multi-dimensional clinical alignment downstream evaluation: In addition to evaluating the enhancement task, we provide several clinically significant downstream tasks for fundus images, including vessel segmentation, DR grading, denoising generalization, and lesion segmentation. 2) Medical expert-guided evaluation design: We introduce a novel dataset that promote comprehensive and fair comparisons between paired and unpaired methods and includes a manual evaluation protocol by medical experts. 3) Valuable insights: Our benchmark study provides a comprehensive and rigorous evaluation of existing methods across different downstream tasks, assisting medical experts in making informed choices. Additionally, we offer further analysis of the challenges faced by existing methods. The code is available at \url{https://github.com/Retinal-Research/EyeBench}
5.1IVJan 3, 2025
Compressed Domain Prior-Guided Video Super-Resolution for Cloud Gaming ContentQizhe Wang, Qian Yin, Zhimeng Huang et al.
Cloud gaming is an advanced form of Internet service that necessitates local terminals to decode within limited resources and time latency. Super-Resolution (SR) techniques are often employed on these terminals as an efficient way to reduce the required bit-rate bandwidth for cloud gaming. However, insufficient attention has been paid to SR of compressed game video content. Most SR networks amplify block artifacts and ringing effects in decoded frames while ignoring edge details of game content, leading to unsatisfactory reconstruction results. In this paper, we propose a novel lightweight network called Coding Prior-Guided Super-Resolution (CPGSR) to address the SR challenges in compressed game video content. First, we design a Compressed Domain Guided Block (CDGB) to extract features of different depths from coding priors, which are subsequently integrated with features from the U-net backbone. Then, a series of re-parameterization blocks are utilized for reconstruction. Ultimately, inspired by the quantization in video coding, we propose a partitioned focal frequency loss to effectively guide the model's focus on preserving high-frequency information. Extensive experiments demonstrate the advancement of our approach.