Can Chen

Can Chen, Xi Chen, Chen Ma et al.

Bi-level optimization, especially the gradient-based category, has been widely used in the deep learning community including hyperparameter optimization and meta-knowledge extraction. Bi-level optimization embeds one problem within another and the gradient-based category solves the outer-level task by computing the hypergradient, which is much more efficient than classical methods such as the evolutionary algorithm. In this survey, we first give a formal definition of the gradient-based bi-level optimization. Next, we delineate criteria to determine if a research problem is apt for bi-level optimization and provide a practical guide on structuring such problems into a bi-level optimization framework, a feature particularly beneficial for those new to this domain. More specifically, there are two formulations: the single-task formulation to optimize hyperparameters such as regularization parameters and the distilled data, and the multi-task formulation to extract meta-knowledge such as the model initialization. With a bi-level formulation, we then discuss four bi-level optimization solvers to update the outer variable including explicit gradient update, proxy update, implicit function update, and closed-form update. Finally, we wrap up the survey by highlighting two prospective future directions: (1) Effective Data Optimization for Science examined through the lens of task formulation. (2) Accurate Explicit Proxy Update analyzed from an optimization standpoint.

Can Chen, Scott T. Weiss, Yang-Yu Liu

Feature selection is a powerful dimension reduction technique which selects a subset of relevant features for model construction. Numerous feature selection methods have been proposed, but most of them fail under the high-dimensional and low-sample size (HDLSS) setting due to the challenge of overfitting. In this paper, we present a deep learning-based method - GRAph Convolutional nEtwork feature Selector (GRACES) - to select important features for HDLSS data. We demonstrate empirical evidence that GRACES outperforms other feature selection methods on both synthetic and real-world datasets.

Hao Zhou, Chengming Hu, Ye Yuan et al.

Large language models (LLMs) have received considerable attention recently due to their outstanding comprehension and reasoning capabilities, leading to great progress in many fields. The advancement of LLM techniques also offers promising opportunities to automate many tasks in the telecommunication (telecom) field. After pre-training and fine-tuning, LLMs can perform diverse downstream tasks based on human instructions, paving the way to artificial general intelligence (AGI)-enabled 6G. Given the great potential of LLM technologies, this work aims to provide a comprehensive overview of LLM-enabled telecom networks. In particular, we first present LLM fundamentals, including model architecture, pre-training, fine-tuning, inference and utilization, model evaluation, and telecom deployment. Then, we introduce LLM-enabled key techniques and telecom applications in terms of generation, classification, optimization, and prediction problems. Specifically, the LLM-enabled generation applications include telecom domain knowledge, code, and network configuration generation. After that, the LLM-based classification applications involve network security, text, image, and traffic classification problems. Moreover, multiple LLM-enabled optimization techniques are introduced, such as automated reward function design for reinforcement learning and verbal reinforcement learning. Furthermore, for LLM-aided prediction problems, we discussed time-series prediction models and multi-modality prediction problems for telecom. Finally, we highlight the challenges and identify the future directions of LLM-enabled telecom networks.

Can Chen, David Heurtel-Depeiges, Robert M. Vernon et al.

Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but lack the structural knowledge essential for many biological applications. To address this, we integrate structural insights from pre-trained protein graph neural networks (pGNNs) into pLMs through a latent-level contrastive learning task. This task aligns residue representations from pLMs with those from pGNNs across multiple proteins, enriching pLMs with inter-protein structural knowledge. Additionally, we incorporate a physical-level task that infuses intra-protein structural knowledge by optimizing pLMs to predict structural tokens. The proposed dual-task framework effectively incorporates both inter-protein and intra-protein structural knowledge into pLMs. Given the variability in the quality of protein structures in PDB, we further introduce a residue loss selection module, which uses a small model trained on high-quality structures to select reliable yet challenging residue losses for the pLM to learn. Applying our structure alignment method to the state-of-the-art ESM2 and AMPLIFY results in notable performance gains across a wide range of tasks, including a 12.7% increase in ESM2 contact prediction. The data, code, and resulting SaESM2 and SaAMPLIFY models will be released on Hugging Face.